{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:39:31Z","timestamp":1787020771811,"version":"build-2736575974"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T00:00:00Z","timestamp":1579651200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T00:00:00Z","timestamp":1579651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Crit Care"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1186\/s13054-019-2720-2","type":"journal-article","created":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T13:03:20Z","timestamp":1579698200000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Biomarkers to delineate bacteremia from candidemia remain a challenging issue"],"prefix":"10.1186","volume":"24","author":[{"given":"Patrick M.","family":"Honore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"David","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachid","family":"Attou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastien","family":"Redant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gallerani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"De Bels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,22]]},"reference":[{"issue":"1","key":"2720_CR1","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1186\/s13054-019-2481-y","volume":"23","author":"A Cortegiani","year":"2019","unstructured":"Cortegiani A, Misseri G, Ippolito M, Bassetti M, Giarratano A, Martin-Loeches I, et al. Procalcitonin levels in candidemia versus bacteremia: a systematic review. Crit Care. 2019;23(1):190. https:\/\/doi.org\/10.1186\/s13054-019-2481-y.","journal-title":"Crit Care"},{"key":"2720_CR2","doi-asserted-by":"publisher","first-page":"1808","DOI":"10.1097\/00003246-200208000-00023","volume":"30","author":"S Hadley","year":"2002","unstructured":"Hadley S, Lee WW, Ruthazer R, Nasraway SA Jr. Candidemia as a cause of septic shock and multiple organ failure in nonimmunocompromised patients. Crit Care Med. 2002;30:1808\u201314; PMID:12163798. https:\/\/doi.org\/10.1097\/00003246-200208000-00023.","journal-title":"Crit Care Med"},{"key":"2720_CR3","doi-asserted-by":"publisher","first-page":"R160","DOI":"10.1186\/cc2372","volume":"6","author":"C Level","year":"2003","unstructured":"Level C, Chauveau P, Guisset O, Cazin MC, Lasseur C, Gabinsky C, et al. Mass transfer, clearance and plasma concentration of procalcitonin during continuous venovenous hemofiltration in patients with septic shock and acute oliguric renal failure. Crit Care. 2003;6:R160\u20136.","journal-title":"Crit Care"},{"issue":"6","key":"2720_CR4","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1097\/MCC.0000000000000542","volume":"24","author":"PM Honor\u00e9","year":"2018","unstructured":"Honor\u00e9 PM, De Bels D, Spapen HD. An update on membranes and cartridges for extracorporeal blood purification in sepsis and septic shock. Curr Opin Crit Care. 2018;24(6):463\u20138. https:\/\/doi.org\/10.1097\/MCC.0000000000000542.","journal-title":"Curr Opin Crit Care"},{"issue":"1","key":"2720_CR5","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1097\/SHK.0000000000000896","volume":"49","author":"W Panpetch","year":"2018","unstructured":"Panpetch W, Somboonna N, Bulan DE, Issara-Amphorn J, Worasilchai N, Finkelman M, et al. Gastrointestinal colonization of candida albicans increases serum (1\u21923)-\u03b2-D-Glucan, without candidemia, and worsens cecal ligation and puncture sepsis in murine model. Shock. 2018;49(1):62\u201370. https:\/\/doi.org\/10.1097\/SHK.0000000000000896.","journal-title":"Shock."},{"key":"2720_CR6","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1186\/s13054-017-1763-5","volume":"21","author":"DR Giacobbe","year":"2017","unstructured":"Giacobbe DR, Mikulska M, Tumbarello M, Furfaro E, Spadaro M, Losito AR, et al. Combined use of serum (1,3)-beta-D-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units. Crit Care. 2017;21:176.","journal-title":"Crit Care"},{"key":"2720_CR7","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s13054-016-1182-z","volume":"20","author":"A Spec","year":"2016","unstructured":"Spec A, Shindo Y, Burnham C-AD, Wilson S, Ablordeppey EA, Beiter ER, et al. T cells from patients with Candida sepsis display a suppressive immunophenotype. Crit Care. 2016;20:15.","journal-title":"Crit Care"},{"key":"2720_CR8","doi-asserted-by":"publisher","first-page":"285","DOI":"10.5152\/TJAR.2016.0013","volume":"44","author":"A Cortegiani","year":"2016","unstructured":"Cortegiani A, Russotto V, Raineri SM, Gregoretti C, Giarratano A. Dying with or because of invasive fungal infection? The role of immunity exhaustion on patient outcome. Turk J Anaesthesiol Reanim. 2016;44:285\u20136.","journal-title":"Turk J Anaesthesiol Reanim"},{"key":"2720_CR9","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1186\/s13054-016-1378-2","volume":"20","author":"V Russotto","year":"2016","unstructured":"Russotto V, Cortegiani A, Raineri SM, Giarratano A. From bedside to bench: the missing brick for patients with fungal sepsis. Crit Care. 2016;20:191.","journal-title":"Crit Care"}],"container-title":["Critical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13054-019-2720-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13054-019-2720-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13054-019-2720-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T19:10:56Z","timestamp":1611169856000},"score":1,"resource":{"primary":{"URL":"https:\/\/ccforum.biomedcentral.com\/articles\/10.1186\/s13054-019-2720-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,22]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["2720"],"URL":"https:\/\/doi.org\/10.1186\/s13054-019-2720-2","relation":{},"ISSN":["1364-8535"],"issn-type":[{"value":"1364-8535","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,22]]},"assertion":[{"value":"10 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"20"}}