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The international lipids in PN Summit, encompassed discussions and the production of consensus guidelines concerning PN intravenous lipid emulsion (ILE) use in critical care. The Lipid Summit participants agreed that the inclusion of fish oil in ILEs is associated with meaningful clinical benefits without signals of harm, based on a strong biological rationale and current clinical evidence. Decisions concerning ILE choice should be made based on current evidence, thus addressing clinical requirements for guidance, particularly as further definitive evidence seems unlikely to occur. In addition, a future of individualized ICU care is envisioned, yielding better clinical outcomes. This approach will require the greater use of intelligent study designs incorporating the use of biomarkers of omega-3 derivatives, inflammatory-resolving processes, and\/or muscle protein breakdown.<\/jats:p>","DOI":"10.1186\/s13054-024-05053-4","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T09:12:08Z","timestamp":1723453928000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients"],"prefix":"10.1186","volume":"28","author":[{"given":"Christian","family":"Stoppe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Martindale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislaw","family":"Klek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip C.","family":"Calder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Wischmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayshil J.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,12]]},"reference":[{"issue":"Suppl 1","key":"5053_CR1","first-page":"S38","volume":"47","author":"E Dresen","year":"2023","unstructured":"Dresen E, Pimiento JM, Patel JJ, Heyland DK, Rice TW, Stoppe C. 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Braun, and DMS, and speaker honoraria from Baxter, B. Braun, and Fresenius Kabi. RM has served as an educational consultant for Fresenius Kabi and Nestl\u00e9. SK has received speaker\u2019s honoraria from Baxter, B. Braun, Fresenius Kabi, Nestle, Nutricia, Shire, and Vipharm and acted as an advisory board member for Fresenius Kabi, Shire, and Tracheron. PC has received consultancy honoraria from BASF, Cargill, DSM, Danone Nutricia Research, and Fresenius Kabi. PW has received investigator-initiated grant funding from the National Institutes of Health, Department of Defense, Abbott, Baxter, and Fresenius Kabi. He has served as a consultant to Abbott, Fresenius Kabi, Baxter, Mend Inc, and Nutricia, received unrestricted gift donations for nutrition research from Musclesound and DSM, and honoraria or travel expenses for CME lectures on improving nutrition care from Abbott, Baxter, Fresenius Kabi, Danone-Nutricia, DSM, and Nestl\u00e9. JP has received consulting honoraria from Fresenius Kabi and Baxter.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"271"}}