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Animal experiments were conducted in accordance with institutional and national guidelines and were approved by the relevant ethics committees (Approval Nos. QYFY WZLL 29506 and 20240701C576020240901128).","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors approved the final version of the manuscript and consented to its publication.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"62"}}