{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T08:00:43Z","timestamp":1782633643672,"version":"3.54.5"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T00:00:00Z","timestamp":1465171200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T00:00:00Z","timestamp":1465171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Lewis and Clark Fund for Exploration and Field Research"},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1501012"],"award-info":[{"award-number":["1501012"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Grand Challenges in Health Program at Princeton University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s13063-016-1406-1","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T13:34:54Z","timestamp":1465220094000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The impact of albendazole treatment on the incidence of viral- and bacterial-induced diarrhea in school children in southern Vietnam: study protocol for a randomized controlled trial"],"prefix":"10.1186","volume":"17","author":[{"given":"Jacqueline M.","family":"Leung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chau Tran Thi","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nghia Ho Dang","family":"Trung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoa Nhu","family":"Thi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chau Nguyen Ngoc","family":"Minh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuy Vu","family":"Thi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinh Thanh","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinh Nguyen Huy","family":"Man","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah C. L.","family":"Knowles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Wolbers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nhat Le Thanh","family":"Hoang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Thwaites","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea L.","family":"Graham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,6,6]]},"reference":[{"issue":"1","key":"1406_CR1","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/1756-3305-7-37","volume":"7","author":"RL Pullan","year":"2014","unstructured":"Pullan RL, Smith JL, Jasrasaria R, Brooker SJ. Global numbers of infection and disease burden of soil transmitted helminth infections in 2010. Parasites & vectors. 2014;7(1):37. doi: 10.1186\/1756-3305-7-37 .","journal-title":"Parasites & vectors"},{"key":"1406_CR2","unstructured":"Bundy DAP, Chan MS, Medley GF, Jamison D, Savioli L. In:\u00a0Global epidemiology of infectious disease: Global burden of disease volume IV.\u00a0Murray CJL, Lopez AD, Mathers CD, editor. Geneva: World Health Organization; 2004. Intestinal nematode infections; pp. 243\u2013300."},{"issue":"Pt 3","key":"1406_CR3","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1017\/S0031182000078410","volume":"109","author":"MS Chan","year":"1994","unstructured":"Chan MS, Medley GF, Jamison D, Bundy DA. The evaluation of potential global morbidity attributable to intestinal nematode infections. Parasitology. 1994;109(Pt 3):373\u201387.","journal-title":"Parasitology"},{"issue":"10","key":"1406_CR4","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1016\/j.ijpara.2010.04.004","volume":"40","author":"S Brooker","year":"2010","unstructured":"Brooker S. Estimating the global distribution and disease burden of intestinal nematode infections: adding up the numbers\u2014a review. Int J Parasitol. 2010;40(10):1137\u201344. doi: 10.1016\/j.ijpara.2010.04.004 .","journal-title":"Int J Parasitol"},{"key":"1406_CR5","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198545996.001.0001","volume-title":"Infectious diseases of humans","author":"RM Anderson","year":"1991","unstructured":"Anderson RM, May RMM. Infectious diseases of humans. Oxford: Oxford University Press; 1991."},{"issue":"Pt 1","key":"1406_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S003118200500884X","volume":"132","author":"DM McKay","year":"2006","unstructured":"McKay DM. The beneficial helminth parasite? Parasitology. 2006;132(Pt 1):1\u201312. doi: 10.1017\/S003118200500884X .","journal-title":"Parasitology"},{"issue":"8","key":"1406_CR7","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.pt.2006.06.003","volume":"22","author":"M Nacher","year":"2006","unstructured":"Nacher M. Worms and malaria: resisting the temptation to generalize. Trends Parasitol. 2006;22(8):350\u20131. doi: 10.1016\/j.pt.2006.06.003 . author reply 1\u20132.","journal-title":"Trends Parasitol"},{"issue":"60","key":"1406_CR8","doi-asserted-by":"publisher","first-page":"60ra88","DOI":"10.1126\/scitranslmed.3001500","volume":"2","author":"MJ Broadhurst","year":"2010","unstructured":"Broadhurst MJ, Leung JM, Kashyap V, McCune JM, Mahadevan U, McKerrow JH, et al. IL-22+ CD4+ T cells are associated with therapeutic Trichuris trichiura infection in an ulcerative colitis patient. Sci Transl Med. 2010;2(60):60ra88. doi: 10.1126\/scitranslmed.3001500 .","journal-title":"Sci Transl Med"},{"key":"1406_CR9","unstructured":"Montresor A, Crompton DWT, Gyorkos TW, Savioli L. Helminth Control in School-Age Children: A Guide for Managers of Control Programmes. 2002. Geneva: World Health Organization."},{"key":"1406_CR10","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000371.pub6","volume":"7","author":"DC Taylor-Robinson","year":"2015","unstructured":"Taylor-Robinson DC, Maayan N, Soares-Weiser K, Donegan S, Garner P. Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin, and school performance. The Cochrane database of systematic reviews. 2015;7, CD000371. doi: 10.1002\/14651858.CD000371.pub6 .","journal-title":"The Cochrane database of systematic reviews."},{"issue":"7","key":"1406_CR11","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1179\/136485906X118468","volume":"100","author":"TW Mwangi","year":"2006","unstructured":"Mwangi TW, Bethony JM, Brooker S. Malaria and helminth interactions in humans: an epidemiological viewpoint. Ann Trop Med Parasitol. 2006;100(7):551\u201370. doi: 10.1179\/136485906X118468 .","journal-title":"Ann Trop Med Parasitol"},{"issue":"5","key":"1406_CR12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030102","volume":"3","author":"PJ Hotez","year":"2006","unstructured":"Hotez PJ, Molyneux DH, Fenwick A, Ottesen E, Ehrlich Sachs S, Sachs JD. Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV\/AIDS, tuberculosis, and malaria. PLoS Med. 2006;3(5), e102. doi: 10.1371\/journal.pmed.0030102 .","journal-title":"PLoS Med"},{"issue":"5","key":"1406_CR13","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.pt.2015.02.004","volume":"31","author":"AB Pedersen","year":"2015","unstructured":"Pedersen AB, Fenton A. The role of antiparasite treatment experiments in assessing the impact of parasites on wildlife. Trends Parasitol. 2015;31(5):200\u201311. doi: 10.1016\/j.pt.2015.02.004 .","journal-title":"Trends Parasitol"},{"issue":"1762","key":"1406_CR14","doi-asserted-by":"publisher","first-page":"20130598","DOI":"10.1098\/rspb.2013.0598","volume":"280","author":"SC Knowles","year":"2013","unstructured":"Knowles SC, Fenton A, Petchey OL, Jones TR, Barber R, Pedersen AB. Stability of within-host-parasite communities in a wild mammal system. Proceedings Biological Sciences\/The Royal Society. 2013;280(1762):20130598. doi: 10.1098\/rspb.2013.0598 .","journal-title":"Proceedings Biological Sciences\/The Royal Society"},{"issue":"4","key":"1406_CR15","doi-asserted-by":"publisher","first-page":"20130205","DOI":"10.1098\/rsbl.2013.0205","volume":"9","author":"AB Pedersen","year":"2013","unstructured":"Pedersen AB, Antonovics J. Anthelmintic treatment alters the parasite community in a wild mouse host. Biol Lett. 2013;9(4):20130205. doi: 10.1098\/rsbl.2013.0205 .","journal-title":"Biol Lett"},{"issue":"1769","key":"1406_CR16","doi-asserted-by":"publisher","first-page":"20131671","DOI":"10.1098\/rspb.2013.1671","volume":"280","author":"AD Blackwell","year":"2013","unstructured":"Blackwell AD, Martin M, Kaplan H, Gurven M. Antagonism between two intestinal parasites in humans: the importance of co-infection for infection risk and recovery dynamics. Proceedings Biological Sciences\/The Royal Society. 2013;280(1769):20131671. doi: 10.1098\/rspb.2013.1671 .","journal-title":"Proceedings Biological Sciences\/The Royal Society"},{"issue":"6218","key":"1406_CR17","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1126\/science.1261714","volume":"347","author":"VO Ezenwa","year":"2015","unstructured":"Ezenwa VO, Jolles AE. Opposite effects of anthelmintic treatment on microbial infection at individual versus population scales. Science. 2015;347(6218):175\u20137. doi: 10.1126\/science.1261714 .","journal-title":"Science"},{"issue":"3","key":"1406_CR18","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1017\/S0031182008005404","volume":"136","author":"N Ferrari","year":"2009","unstructured":"Ferrari N, Cattadori IM, Rizzoli A, Hudson PJ. Heligmosomoides polygyrus reduces infestation of Ixodes ricinus in free-living yellow-necked mice, Apodemus flavicollis. Parasitology. 2009;136(3):305\u201316. doi: 10.1017\/S0031182008005404 .","journal-title":"Parasitology."},{"issue":"6","key":"1406_CR19","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1093\/tropej\/40.6.329","volume":"40","author":"EK Rousham","year":"1994","unstructured":"Rousham EK. An increase in Giardia duodenalis infection among children receiving periodic anthelmintic treatment in Bangladesh. J Trop Pediatr. 1994;40(6):329\u201333.","journal-title":"J Trop Pediatr"},{"key":"1406_CR20","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/B978-0-12-385897-9.00004-5","volume":"74","author":"AR Jex","year":"2011","unstructured":"Jex AR, Lim YA, Bethony JM, Hotez PJ, Young ND, Gasser RB. Soil-transmitted helminths of humans in Southeast Asia\u2014towards integrated control. Adv Parasitol. 2011;74:231\u201365. doi: 10.1016\/B978-0-12-385897-9.00004-5 .","journal-title":"Adv Parasitol."},{"issue":"9832","key":"1406_CR21","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1016\/S0140-6736(12)60560-1","volume":"379","author":"L Liu","year":"2012","unstructured":"Liu L, Johnson HL, Cousens S, Perin J, Scott S, Lawn JE, et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012;379(9832):2151\u201361. doi: 10.1016\/S0140-6736(12)60560-1 .","journal-title":"Lancet"},{"issue":"5","key":"1406_CR22","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.4269\/ajtmh.14-0655","volume":"92","author":"CN Thompson","year":"2015","unstructured":"Thompson CN, Phan MV, Hoang NV, Minh PV, Vinh NT, Thuy CT, et al. A prospective multi-center observational study of children hospitalized with diarrhea in Ho Chi Minh City, Vietnam. Am J Trop Med Hyg. 2015;92(5):1045\u201352. doi: 10.4269\/ajtmh.14-0655 .","journal-title":"Am J Trop Med Hyg."},{"issue":"12","key":"1406_CR23","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1016\/S2221-1691(13)60001-5","volume":"2","author":"JX Wang","year":"2012","unstructured":"Wang JX, Pan CS, Cui LW, Chen X. Application of a real-time PCR method for detecting and monitoring hookworm Necator americanus infections in Southern China. Asian Pacific journal of tropical biomedicine. 2012;2(12):925\u20139. doi: 10.1016\/S2221-1691(13)60001-5 .","journal-title":"Asian Pacific journal of tropical biomedicine"},{"key":"1406_CR24","unstructured":"General Statistics Office of Viet Nam. Population and employment. 2013. http:\/\/www.gso.gov.vn\/Default_en.aspx?tabid=491 . Accessed 8 Mar 2016."},{"key":"1406_CR25","unstructured":"Hoa NT, Huong TC, Diep LTN. Knowledge of parents and practice of children in hookworm infestation among primary pupils in Cu Chi district, HCM City. Ho Chi Minh Med Magazine. 2009;13(4):218-24."},{"issue":"4","key":"1406_CR26","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1172\/JCI34261","volume":"118","author":"PJ Hotez","year":"2008","unstructured":"Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. J Clin Invest. 2008;118(4):1311\u201321. doi: 10.1172\/JCI34261 .","journal-title":"J Clin Invest"},{"key":"1406_CR27","volume-title":"Helminth control in school-age children: a guide for managers of control programmes","author":"A Montresor","year":"2002","unstructured":"Montresor A. Helminth control in school-age children: a guide for managers of control programmes. Geneva: World Health Organization; 2002."},{"issue":"6","key":"1406_CR28","first-page":"1029","volume":"15","author":"M Roche","year":"1966","unstructured":"Roche M, Layrisse M. The nature and causes of \u201chookworm anemia.\u201d. Am J Trop Med Hyg. 1966;15(6):1029\u2013102.","journal-title":"Am J Trop Med Hyg"},{"key":"1406_CR29","unstructured":"World Health Organization. Iron deficiency anaemia: assessment, prevention and control. A guide for programme managers. World Health Organization; 2001."},{"key":"1406_CR30","unstructured":"World Health Organization. WHO model prescribing information: drugs used in parasitic diseases. Second Edition. 1995. Geneva: World Health Organization."},{"issue":"6","key":"1406_CR31","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.4269\/ajtmh.12-0726","volume":"88","author":"R Mejia","year":"2013","unstructured":"Mejia R, Vicuna Y, Broncano N, Sandoval C, Vaca M, Chico M, et al. A novel, multi-parallel, real-time polymerase chain reaction approach for eight gastrointestinal parasites provides improved diagnostic capabilities to resource-limited at-risk populations. Am J Trop Med Hyg. 2013;88(6):1041\u20137. doi: 10.4269\/ajtmh.12-0726 .","journal-title":"Am J Trop Med Hyg"},{"issue":"1","key":"1406_CR32","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.jviromet.2012.09.021","volume":"187","author":"TT Dung","year":"2013","unstructured":"Dung TT, Phat VV, Nga TV, My PV, Duy PT, Campbell JI, et al. The validation and utility of a quantitative one-step multiplex RT real-time PCR targeting rotavirus A and norovirus. J Virol Methods. 2013;187(1):138\u201343. doi: 10.1016\/j.jviromet.2012.09.021 .","journal-title":"J Virol Methods"},{"key":"1406_CR33","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.ijid.2015.03.013","volume":"35","author":"KL Anders","year":"2015","unstructured":"Anders KL, Thompson CN, Thuy NT, Nguyet NM, le Tu TP, Dung TT, et al. The epidemiology and aetiology of diarrhoeal disease in infancy in southern Vietnam: a birth cohort study. Int J Infect Dis. 2015;35:3\u201310. doi: 10.1016\/j.ijid.2015.03.013 .","journal-title":"Int J Infect Dis."},{"key":"1406_CR34","unstructured":"World Health Organization. The treatment of diarrhea: a manual for physicians and other senior health workers\u2014 4th revision. 2005. Geneva: World Health Organization."},{"issue":"3","key":"1406_CR35","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1093\/ije\/23.3.617","volume":"23","author":"SS Morris","year":"1994","unstructured":"Morris SS, Cousens SN, Lanata CF, Kirkwood BR. Diarrhoea\u2014defining the episode. Int J Epidemiol. 1994;23(3):617\u201323.","journal-title":"Int J Epidemiol"},{"issue":"2","key":"1406_CR36","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1017\/S0950268801005933","volume":"127","author":"DW Isenbarger","year":"2001","unstructured":"Isenbarger DW, Hien BT, Ha HT, Ha TT, Bodhidatta L, Pang LW, et al. Prospective study of the incidence of diarrhoea and prevalence of bacterial pathogens in a cohort of Vietnamese children along the Red River. Epidemiol Infect. 2001;127(2):229\u201336.","journal-title":"Epidemiol Infect"},{"issue":"23","key":"1406_CR37","doi-asserted-by":"publisher","first-page":"7537","DOI":"10.1128\/AEM.01541-09","volume":"75","author":"PD Schloss","year":"2009","unstructured":"Schloss PD, Westcott SL, Ryabin T, Hall JR, Hartmann M, Hollister EB, et al. Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl Environ Microbiol. 2009;75(23):7537\u201341. doi: 10.1128\/AEM.01541-09 .","journal-title":"Appl Environ Microbiol"},{"issue":"6","key":"1406_CR38","doi-asserted-by":"publisher","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","volume":"12","author":"N Segata","year":"2011","unstructured":"Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, et al. Metagenomic biomarker discovery and explanation. Genome Biol. 2011;12(6):R60. doi: 10.1186\/gb-2011-12-6-r60 .","journal-title":"Genome Biol"},{"issue":"3","key":"1406_CR39","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/S1053-4296(03)00031-6","volume":"13","author":"A Trotti","year":"2003","unstructured":"Trotti A, Colevas AD, Setser A, Rusch V, Jaques D, Budach V, et al. CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol. 2003;13(3):176\u201381. doi: 10.1016\/S1053-4296(03)00031-6 .","journal-title":"Semin Radiat Oncol"},{"key":"1406_CR40","volume-title":"Soil-transmitted helminthiases: eliminating soil-transmitted helminthiases as a public health problem in children: progress report 2001\u20132010 and strategic plan 2011\u20132020","author":"World Health Organization","year":"2012","unstructured":"World Health Organization. Soil-transmitted helminthiases: eliminating soil-transmitted helminthiases as a public health problem in children: progress report 2001\u20132010 and strategic plan 2011\u20132020. Geneva: World Health Organization; 2012."},{"key":"1406_CR41","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1186\/1471-2334-10-277","volume":"10","author":"P Kirwan","year":"2010","unstructured":"Kirwan P, Jackson AL, Asaolu SO, Molloy SF, Abiona TC, Bruce MC, et al. Impact of repeated four-monthly anthelmintic treatment on Plasmodium infection in preschool children: a double-blind placebo-controlled randomized trial. BMC Infect Dis. 2010;10:277. doi: 10.1186\/1471-2334-10-277 .","journal-title":"BMC Infect Dis."},{"issue":"3","key":"1406_CR42","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057899","volume":"8","author":"AE Wiria","year":"2013","unstructured":"Wiria AE, Hamid F, Wammes LJ, Kaisar MM, May L, Prasetyani MA, et al. The effect of three-monthly albendazole treatment on malarial parasitemia and allergy: a household-based cluster-randomized, double-blind, placebo-controlled trial. PLoS One. 2013;8(3), e57899. doi: 10.1371\/journal.pone.0057899 .","journal-title":"PLoS One"},{"key":"1406_CR43","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv382","author":"S Kepha","year":"2015","unstructured":"Kepha S, Nuwaha F, Nikolay B, Gichuki P, Mwandawiro CS, Mwinzi PN, et al. Effect of repeated anthelminthic treatment on malaria in school children in Kenya: a randomized, open-label, equivalence trial. J Infect Dis. 2015. doi: 10.1093\/infdis\/jiv382 .","journal-title":"J Infect Dis"},{"key":"1406_CR44","doi-asserted-by":"publisher","unstructured":"Steinmann P, Utzinger J, Du ZW, Jiang JY, Chen JX, Hattendorf J, et al. Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial. PLoS One. 2011;6(9):e25003. doi: 10.1371\/journal.pone.0025003 .","DOI":"10.1371\/journal.pone.0025003"},{"issue":"5","key":"1406_CR45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001621","volume":"6","author":"TW Jia","year":"2012","unstructured":"Jia TW, Melville S, Utzinger J, King CH, Zhou XN. Soil-transmitted helminth reinfection after drug treatment: a systematic review and meta-analysis. PLoS Negl Trop Dis. 2012;6(5), e1621. doi: 10.1371\/journal.pntd.0001621 .","journal-title":"PLoS Negl Trop Dis"},{"issue":"Suppl","key":"1406_CR46","doi-asserted-by":"publisher","first-page":"S113","DOI":"10.1017\/S0031182000007290","volume":"121","author":"J Horton","year":"2000","unstructured":"Horton J. Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitology. 2000;121(Suppl):S113\u201332.","journal-title":"Parasitology."},{"issue":"6","key":"1406_CR47","doi-asserted-by":"publisher","first-page":"1678","DOI":"10.1093\/ije\/dyr152","volume":"40","author":"WP Schmidt","year":"2011","unstructured":"Schmidt WP, Arnold BF, Boisson S, Genser B, Luby SP, Barreto ML, et al. Epidemiological methods in diarrhoea studies\u2014an update. Int J Epidemiol. 2011;40(6):1678\u201392.","journal-title":"Int J Epidemiol"},{"key":"1406_CR48","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1186\/1471-2458-12-276","volume":"12","author":"LM Lamberti","year":"2012","unstructured":"Lamberti LM, Fischer Walker CL, Black RE. Systematic review of diarrhea duration and severity in children and adults in low- and middle-income countries. BMC Public Health. 2012;12:276. doi: 10.1186\/1471-2458-12-276 .","journal-title":"BMC Public Health."},{"issue":"3-4","key":"1406_CR49","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.ijpara.2012.11.011","volume":"43","author":"HJ McSorley","year":"2013","unstructured":"McSorley HJ, Hewitson JP, Maizels RM. Immunomodulation by helminth parasites: defining mechanisms and mediators. Int J Parasitol. 2013;43(3-4):301\u201310. doi: 10.1016\/j.ijpara.2012.11.011 .","journal-title":"Int J Parasitol"},{"issue":"3-4","key":"1406_CR50","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.ijpara.2012.10.015","volume":"43","author":"JM Leung","year":"2013","unstructured":"Leung JM, Loke P. A role for IL-22 in the relationship between intestinal helminths, gut microbiota and mucosal immunity. Int J Parasitol. 2013;43(3-4):253\u20137. doi: 10.1016\/j.ijpara.2012.10.015 .","journal-title":"Int J Parasitol"}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-016-1406-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13063-016-1406-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-016-1406-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-016-1406-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T11:14:07Z","timestamp":1718622847000},"score":1,"resource":{"primary":{"URL":"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-016-1406-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,6]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["1406"],"URL":"https:\/\/doi.org\/10.1186\/s13063-016-1406-1","relation":{},"ISSN":["1745-6215"],"issn-type":[{"value":"1745-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,6]]},"assertion":[{"value":"2 December 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 June 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"279"}}