{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:58:53Z","timestamp":1791953933911,"version":"4.3.4"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"DEB Group Ltd, Denby, UK","award":["?"],"award-info":[{"award-number":["?"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s13063-017-1803-0","type":"journal-article","created":{"date-parts":[[2017,2,28]],"date-time":"2017-02-28T14:13:22Z","timestamp":1488291202000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The effectiveness of a skin care program for the prevention of contact dermatitis in health care workers (the Healthy Hands Project): study protocol for a cluster randomized controlled trial"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1408-4351","authenticated-orcid":false,"given":"Maryam","family":"Soltanipoor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanja","family":"Kezic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith K.","family":"Sluiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Rustemeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,2,28]]},"reference":[{"key":"1803_CR1","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1600-0536.2012.02105.x","volume":"67","author":"KS Ibler","year":"2012","unstructured":"Ibler KS, Jemec GB, Flyvholm MA. Hand eczema: prevalence and risk factors of hand eczema in a population of 2274 health care workers. Contact Dermatitis. 2012;67:200\u20137.","journal-title":"Contact Dermatitis."},{"key":"1803_CR2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1159\/000441590","volume":"49","author":"M Fartasch","year":"2016","unstructured":"Fartasch M. Wet work and barrier function. Curr Probl Dermatol. 2016;49:144\u201351.","journal-title":"Curr Probl Dermatol."},{"key":"1803_CR3","unstructured":"German Federal Ministry of Labour and Social Affairs.2006. Technical rules for hazardous substances. Risk resulting from skin contact \u2013 determination, evaluation, measures (TRGS 401) [Internet]. Germany. http:\/\/www.baua.de\/nn_54598\/en\/Topics-from-A-to-Z\/Hazardous-Substances\/TRGS\/pdf\/TRGS-401.pdf . Accessed 11 Nov 2013."},{"issue":"1","key":"1803_CR4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/cod.12131","volume":"70","author":"MJ Visser","year":"2014","unstructured":"Visser MJ, Verberk MM, van Dijk FJ. Wet work and hand eczema in apprentice nurses: part I. Contact Dermatitis. 2014;70(1):44\u201355.","journal-title":"Contact Dermatitis"},{"key":"1803_CR5","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1093\/ije\/22.2.288","volume":"22","author":"HA Smit","year":"1993","unstructured":"Smit HA, Burdorf A, Coenraads PJ. Prevalence of hand dermatitis in different occupations. Int J Epidemiol. 1993;22:288\u201393.","journal-title":"Int J Epidemiol."},{"issue":"4","key":"1803_CR6","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1600-0536.2007.01179.x","volume":"57","author":"TL Diepgen","year":"2007","unstructured":"Diepgen TL, Agner T, Aberer W. Management of chronic hand eczema. Contact Dermatitis. 2007;57(4):203\u201310.","journal-title":"Contact Dermatitis"},{"issue":"2","key":"1803_CR7","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1600-0536.2010.01825.x","volume":"64","author":"RF Gils Van","year":"2011","unstructured":"Van Gils RF, van der Valk PGM, Bruynzeel DJ, Coenraads PJ, Boot CRL, Anema JR. Prevention of occupational hand eczema. A systematic review. Contact Dermatitis. 2011;64(2):63\u201372.","journal-title":"Contact Dermatitis"},{"key":"1803_CR8","unstructured":"Prevention of contact dermatitis: a national guideline. Dutch Society of Occupational Health (NvAB). 2006."},{"key":"1803_CR9","unstructured":"Contact dermatitis: a national guideline. Netherlands Society of Dermatology and Venereology (NVDV). 2013"},{"key":"1803_CR10","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1111\/j.1365-2133.2010.09643.x","volume":"162","author":"C Williams","year":"2009","unstructured":"Williams C, Wilkinson SM, McShane P, et al. A double-blind, randomized study to assess the effectiveness of different moisturizers in preventing dermatitis induce by hand washing to stimulate healthcare use. Br J Dermatol. 2009;162:1088\u201392.","journal-title":"Br J Dermatol."},{"key":"1803_CR11","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/j.1365-2133.2009.09485.x","volume":"162","author":"B K\u00fctting","year":"2010","unstructured":"K\u00fctting B, Baumeister T, Weistenh\u00f6fer W, et al. Effectiveness of skin protection measures in prevention of occupational hand eczema: results of a prospective randomized controlled trial over a follow-up period of 1\u00a0year. Br J Dermatol. 2010;162:362\u201370.","journal-title":"Br J Dermatol."},{"key":"1803_CR12","doi-asserted-by":"crossref","unstructured":"van Kampf G, Ennen J. Regular use of a hand cream can attenuate skin dryness and roughness caused by frequent hand washing, vol. 6. 2006. p. 1.","DOI":"10.1186\/1471-5945-6-1"},{"issue":"2","key":"1803_CR13","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1365-2133.2009.09226.x","volume":"161","author":"M Dulon","year":"2009","unstructured":"Dulon M, Pohrt U, Skudlik C, Nienhaus A. Prevention of occupational skin disease in geriatric nurses. Br J Dermatol. 2009;161(2):337\u201344.","journal-title":"Br J Dermatol"},{"key":"1803_CR14","doi-asserted-by":"crossref","first-page":"e7822","DOI":"10.1136\/bmj.e7822","volume":"345","author":"KS Ibler","year":"2012","unstructured":"Ibler KS, Jemec GB, Diepgen TL. Skin care education and individual counselling versus treatment as usual in healthcare workers with hand eczema: randomised clinical trial. BMJ. 2012;345:e7822.","journal-title":"BMJ."},{"key":"1803_CR15","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00420-003-0437-6","volume":"76","author":"B K\u00fctting","year":"2003","unstructured":"K\u00fctting B, Drexler H. Effectiveness of skin protection creams as a preventive measure in occupational dermatitis: a critical update according to criteria of evidence based medicine. Int Arch Occup Environ Health. 2003;76:253\u20139.","journal-title":"Int Arch Occup Environ Health."},{"key":"1803_CR16","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1034\/j.1600-0536.2001.044004229.x","volume":"44","author":"E Held","year":"2001","unstructured":"Held E, Lund H, Agner T. Effect of different moisturizers on SLS-irritated human skin. Contact Dermatitis. 2001;44:229\u201334.","journal-title":"Contact Dermatitis."},{"key":"1803_CR17","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1600-0536.1997.tb00213.x","volume":"36","author":"M Loden","year":"1997","unstructured":"Loden M. Barrier recovery and influence of irritant stimuli in skin treated with a moisturizing cream. Contact Dermatitis. 1997;36:256\u201360.","journal-title":"Contact Dermatitis."},{"key":"1803_CR18","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1034\/j.1600-0536.2001.440509.x","volume":"44","author":"E Held","year":"2001","unstructured":"Held E, Wolff C, Gyntelberg F, Agner T. Prevention of work-related skin problems in student auxiliary nurses: an intervention study. Contact Dermatitis. 2001;44:297\u2013303.","journal-title":"Contact Dermatitis."},{"key":"1803_CR19","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1046\/j.1439-0353.2005.04798.x","volume":"3","author":"E Weisshaar","year":"2005","unstructured":"Weisshaar E, Radulescu M. Skin protection and skin disease prevention courses for secondary prevention in healthcare workers: first results after two years of implementation. J Dtsch Dermatol Ges. 2005;3:33\u20138.","journal-title":"J Dtsch Dermatol Ges."},{"issue":"8","key":"1803_CR20","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.ajic.2016.04.215","volume":"44","author":"J William Kelly","year":"2016","unstructured":"J William Kelly, Blackhurst D, McAtee, Steed C. Electronic hand hygiene monitoring as a tool for reducing healthcare-associated methicillin-resistant Staphylococcus aureus infection. Am J Infect Control. 2016;44(8):956\u20137.","journal-title":"Am J Infect Control"},{"key":"1803_CR21","first-page":"CD000259","volume":"2","author":"G Jamtvedt","year":"2006","unstructured":"Jamtvedt G, et al. Audit and feedback: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2006;2:CD000259.","journal-title":"Cochrane Database Syst Rev"},{"key":"1803_CR22","first-page":"CD000259","volume":"6","author":"N Ivers","year":"2012","unstructured":"Ivers N, et al. Audit and feedback: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev. 2012;6:CD000259.","journal-title":"Cochrane Database Syst Rev"},{"issue":"04","key":"1803_CR23","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2307\/30147022","volume":"11","author":"PM Dubbert","year":"1990","unstructured":"Dubbert PM, et al. Increasing ICU staff handwashing: effects of education and group feedback. Infect Control Hosp Epidemiol. 1990;11(04):191\u20133.","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"2","key":"1803_CR24","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1365-2133.2004.06305.x","volume":"152","author":"E Held","year":"2005","unstructured":"Held E, Skoet R, Johansen JD. The hand eczema severity index (HECSI): a scoring system for clinical assessment of hand eczema. A study of inter- and intraobserver reliability. Br J Dermatol. 2005;152(2):302\u20137.","journal-title":"Br J Dermatol"},{"issue":"Suppl 1","key":"1803_CR25","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1396-0296.2004.04S1005.x","volume":"17","author":"AV Rawlings","year":"2004","unstructured":"Rawlings AV, Harding CR. Moisturization and skin barrier function. Dermatol Ther. 2004;17 Suppl 1:43\u20138.","journal-title":"Dermatol Ther."},{"issue":"7","key":"1803_CR26","doi-asserted-by":"crossref","first-page":"880","DOI":"10.2340\/00015555-2363","volume":"96","author":"I Angelova-Fischer","year":"2016","unstructured":"Angelova-Fischer I, Stilla TR, Kezic S. Barrier function and natural moisturizing factor levels after cumulative exposure to short-chain aliphatic alcohols and detergents: results of occlusion-modified tandem repeated irritation test. Acta Derm Venereol. 2016;96(7):880\u20134.","journal-title":"Acta Derm Venereol"},{"issue":"1","key":"1803_CR27","first-page":"13","volume":"61","author":"M Robinson","year":"2010","unstructured":"Robinson M, et al. Natural moisturizing factors (NMF) in the stratum corneum (SC). I. Effects of lipid extraction and soaking. J Cosmet Sci. 2010;61(1):13.","journal-title":"J Cosmet Sci"},{"issue":"1","key":"1803_CR28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/15569527.2010.517230","volume":"30","author":"CY Wang","year":"2011","unstructured":"Wang CY, Maibach HI. Why minimally invasive skin sampling techniques? A bright scientific future. Cutan Ocul Toxicol. 2011;30(1):1\u20136.","journal-title":"Cutan Ocul Toxicol"},{"key":"1803_CR29","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1080\/00032719.2013.789881","volume":"46","author":"I Dapic","year":"2013","unstructured":"Dapic I, Yau N, Kezic S, Kammeyer A. Evaluation of a HPLC method for the determination of natural moisturising factors in the human stratum corneum. Anal Lett. 2013;46:2133\u201344.","journal-title":"Anal Lett."},{"key":"1803_CR30","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.jhep.2005.12.006","volume":"44","author":"C Gluud","year":"2006","unstructured":"Gluud C. The culture of designing hepato-biliary randomised trials. J Hepatol. 2006;44:607\u201315.","journal-title":"J Hepatol."},{"key":"1803_CR31","doi-asserted-by":"crossref","first-page":"c332","DOI":"10.1136\/bmj.c332","volume":"340","author":"KF Schulz","year":"2010","unstructured":"Schulz KF, Altman DG, Moher D, for the CONSORT Group. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. BMJ. 2010;340:c332.","journal-title":"BMJ"},{"issue":"8","key":"1803_CR32","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1001\/jama.2013.879","volume":"309","author":"M Calvert","year":"2013","unstructured":"Calvert M, Blazeby J, Altman DG, Revicki DA, Moher D, Brundage MD, CONSORT PRO. Group. Reporting of patient-reported outcomes in randomized trials: the CONSORT PRO extension. JAMA. 2013;309(8):814\u201322.","journal-title":"JAMA"},{"key":"1803_CR33","doi-asserted-by":"crossref","first-page":"e5661","DOI":"10.1136\/bmj.e5661","volume":"345","author":"MK Campbell","year":"2012","unstructured":"Campbell MK, Piaggio G, Elbourne DR, Altman DG, for the CONSORT Group. Consort 2010 statement: extension to cluster randomised trials. BMJ. 2012;345:e5661.","journal-title":"BMJ"},{"issue":"1","key":"1803_CR34","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s13063-016-1255-y","volume":"17","author":"I Madan","year":"2016","unstructured":"Madan I, Parsons V, Cookson B. A behavioural change package to prevent hand dermatitis in nurses working in the national health service (the SCIN trial): study protocol for a cluster randomised controlled trial. Trials. 2016;17(1):145.","journal-title":"Trials"},{"issue":"2","key":"1803_CR35","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1371\/journal.pmed.0040061","volume":"4","author":"I Boutron","year":"2007","unstructured":"Boutron I, Guittet L. Reporting methods of blinding in randomized trials assessing nonpharmacological treatments. PLoS Med. 2007;4(2):e61.","journal-title":"PLoS Med"},{"issue":"3","key":"1803_CR36","doi-asserted-by":"crossref","first-page":"200","DOI":"10.7326\/0003-4819-158-3-201302050-00583","volume":"158","author":"AW Chan","year":"2013","unstructured":"Chan AW, Tetzlaff JM, Altman DG, Laupacis A, Gotzsche PC, Krleza-Jeric K, et al. SPIRIT 2013 statement: defining standard protocol items for clinical trials. Ann Intern Med. 2013;158(3):200\u20137.","journal-title":"Ann Intern Med"}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-017-1803-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T06:05:46Z","timestamp":1601705146000},"score":1,"resource":{"primary":{"URL":"http:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-017-1803-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,28]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1803"],"URL":"https:\/\/doi.org\/10.1186\/s13063-017-1803-0","relation":{},"ISSN":["1745-6215"],"issn-type":[{"value":"1745-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,28]]},"article-number":"92"}}