{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:05:10Z","timestamp":1780049110244,"version":"3.53.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"St. Antonius Research Foundation","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s13063-017-2142-x","type":"journal-article","created":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T11:21:46Z","timestamp":1503487306000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Perioperative antibiotic prophylaxis in the treatment of acute cholecystitis (PEANUTS II trial): study protocol for a randomized controlled trial"],"prefix":"10.1186","volume":"18","author":[{"given":"Charlotte S.","family":"Loozen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hjalmar C.","family":"van Santvoort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoinette A. W.","family":"van Geloven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grard A. P.","family":"Nieuwenhuijzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip R.","family":"de Reuver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark H. G.","family":"Besselink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Vlaminckx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes C.","family":"Kelder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherijne A. J.","family":"Knibbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamila","family":"Boerma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,8,23]]},"reference":[{"key":"2142_CR1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1001\/jama.2014.7586","volume":"312","author":"JM Regimbeau","year":"2014","unstructured":"Regimbeau JM, Fuks D, Pautrat K, Mauvais F, Haccart V, Msika S, et al. Effect of postoperative antibiotic administration on postoperative infection following cholecystectomy for acute calculous cholecystitis: a randomized clinical trial. JAMA. 2014;312:145\u201354.","journal-title":"JAMA"},{"key":"2142_CR2","first-page":"2049","volume":"144","author":"ME Kasteren van","year":"2000","unstructured":"van Kasteren ME, Gyssens IC, Kullberg BJ, Bruining HA, Stobberingh EE, Goris RJ, Foundation Antibiotics Policy Team. Optimizing antibiotics policy in the Netherlands: V. SWAB guidelines for perioperative antibiotic prophylaxis [in Dutch]. Ned Tijdschr Geneeskd. 2000;144:2049\u201355. A published erratum appears in Ned Tijdschr Geneeskd. 2001;145:112.","journal-title":"Ned Tijdschr Geneeskd"},{"key":"2142_CR3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1089\/sur.2009.9930","volume":"11","author":"JS Solomkin","year":"2010","unstructured":"Solomkin JS, Mazuski JE, Bradley JS, Rodvold KA, Goldstein EJ, Baron EJ, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Surg Infect (Larchmt). 2010;11:79\u2013109.","journal-title":"Surg Infect (Larchmt)"},{"key":"2142_CR4","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s00534-012-0572-0","volume":"20","author":"H Gomi","year":"2013","unstructured":"Gomi H, Solomkin JS, Takada T, Strasberg SM, Pitt HA, Yoshida M, et al. TG13 antimicrobial therapy for acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci. 2013;20:60\u201370.","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"2142_CR5","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1089\/lap.2010.0436","volume":"21","author":"RC Yan","year":"2011","unstructured":"Yan RC, Shen SQ, Chen ZB, Lin FS, Riley J. The role of prophylactic antibiotics in laparoscopic cholecystectomy in preventing postoperative infection: a meta-analysis. J Laparoendosc Adv Surg Tech A. 2011;21:301\u20136.","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"2142_CR6","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1089\/sur.2008.084","volume":"11","author":"N Sharma","year":"2010","unstructured":"Sharma N, Garg PK, Hadke NS, Choudhary D. Role of prophylactic antibiotics in laparoscopic cholecystectomy and risk factors for surgical site infection: a randomized controlled trial. Surg Infect (Larchmt). 2010;11:367\u201370.","journal-title":"Surg Infect (Larchmt)"},{"key":"2142_CR7","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1007\/s11605-008-0681-x","volume":"12","author":"A Choudhary","year":"2008","unstructured":"Choudhary A, Bechtold ML, Puli SR, Othman MO, Roy PK. Role of prophylactic antibiotics in laparoscopic cholecystectomy: a meta-analysis. J Gastrointest Surg. 2008;12:1847\u201353.","journal-title":"J Gastrointest Surg"},{"key":"2142_CR8","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.amjsurg.2006.01.050","volume":"191","author":"W Chang","year":"2006","unstructured":"Chang W, Lee K, Chuang S, Wang S, Kuo K, Chen J, et al. The impact of prophylactic antibiotics on postoperative infection complication in elective laparoscopic cholecystectomy: a prospective randomized study. Am J Surg. 2006;191:721\u20135.","journal-title":"Am J Surg"},{"key":"2142_CR9","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1007\/s00464-002-8866-y","volume":"17","author":"M Koc","year":"2003","unstructured":"Koc M, Zulfikaroglu B, Kece C, Ozalp N. A prospective randomized study of prophylactic antibiotics in elective laparoscopic cholecystectomy. Surg Endosc. 2003;17:1716\u20138.","journal-title":"Surg Endosc"},{"key":"2142_CR10","unstructured":"World Health Organization. Antimicrobial resistance. Updated Sept 2016. \nhttp:\/\/www.who.int\/mediacentre\/factsheets\/fs194\/en\/\n\n. Accessed 17 Jan 2017."},{"key":"2142_CR11","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s00534-006-1159-4","volume":"14","author":"M Hirota","year":"2007","unstructured":"Hirota M, Takada T, Kawarada Y, Nimura Y, Miura F, Hirata K, et al. Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:78\u201382.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"2142_CR12","unstructured":"Nederlands Vereniging voor Heelkunde. The Dutch guidelines for the treatment of gallstone disease [in Dutch]. 2016. \nhttp:\/\/heelkunde.nl\/nieuws\/richtlijn-galsteenlijden-geautoriseerd\n\n. Accessed 17 Jan 2017."},{"key":"2142_CR13","doi-asserted-by":"crossref","first-page":"200","DOI":"10.7326\/0003-4819-158-3-201302050-00583","volume":"158","author":"A Chan","year":"2013","unstructured":"Chan A, Tetzlaff JM, Altman DG, Laupacis A, G\u00f8tzsche PC, Krle\u017ea-Jeri\u0107 K, et al. SPIRIT 2013 statement: defining standard protocol items for clinical trials. Ann Intern Med. 2013;158:200\u20137.","journal-title":"Ann Intern Med"},{"key":"2142_CR14","volume-title":"Data monitoring committees in clinical trials: a practical perspective: Chichester","author":"SS Ellenberg","year":"2003","unstructured":"Ellenberg SS, Fleming TR, DeMets DL. Data monitoring committees in clinical trials: a practical perspective: Chichester. UK: John Wiley & Sons; 2003."},{"key":"2142_CR15","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00534-012-0563-1","volume":"20","author":"F Miura","year":"2013","unstructured":"Miura F, Takada T, Strasberg SM, Solomkin JS, Pitt HA, Gouma DJ, et al. TG13 flowchart for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci. 2013;20:47\u201354.","journal-title":"J Hepatobiliary Pancreat Sci"}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-017-2142-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T11:23:32Z","timestamp":1503487412000},"score":1,"resource":{"primary":{"URL":"http:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-017-2142-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,23]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["2142"],"URL":"https:\/\/doi.org\/10.1186\/s13063-017-2142-x","relation":{},"ISSN":["1745-6215"],"issn-type":[{"value":"1745-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,23]]},"article-number":"390"}}