{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T10:20:51Z","timestamp":1767176451137,"version":"build-2238731810"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T00:00:00Z","timestamp":1536710400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["R215\u00ad2015\u00ad4121"],"award-info":[{"award-number":["R215\u00ad2015\u00ad4121"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s13063-018-2860-8","type":"journal-article","created":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T01:01:55Z","timestamp":1536714115000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial"],"prefix":"10.1186","volume":"19","author":[{"given":"Caroline V.","family":"Ott","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maj","family":"Vinberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher R.","family":"Bowie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen Margrethe","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gitte M.","family":"Knudsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars V.","family":"Kessing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamilla W.","family":"Miskowiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,9,12]]},"reference":[{"key":"2860_CR1","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.jad.2016.06.063","volume":"205","author":"B Cullen","year":"2016","unstructured":"Cullen B, Ward J, Graham NA, Deary IJ, Pell JP, Smith DJ, et al. Prevalence and correlates of cognitive impairment in euthymic adults with bipolar disorder: a systematic review. J Affect Disord. 2016;205:165\u201381.","journal-title":"J Affect Disord"},{"key":"2860_CR2","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.jad.2016.08.018","volume":"205","author":"JH Jensen","year":"2016","unstructured":"Jensen JH, Knorr U, Vinberg M, Kessing LV, Miskowiak KW. Discrete neurocognitive subgroups in fully or partially remitted bipolar disorder: associations with functional abilities. J Affect Disord. 2016;205:378\u201386.","journal-title":"J Affect Disord"},{"key":"2860_CR3","doi-asserted-by":"publisher","first-page":"3083","DOI":"10.1017\/S0033291714000439","volume":"44","author":"KE Burdick","year":"2014","unstructured":"Burdick KE, Russo M, Frangou S, Mahon K, Braga RJ, Shanahan M, et al. Empirical evidence for discrete neurocognitive subgroups in bipolar disorder: clinical implications. Psychol Med. 2014;44:3083.","journal-title":"Psychol Med"},{"key":"2860_CR4","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1111\/bdi.12341","volume":"17","author":"BT Baune","year":"2015","unstructured":"Baune BT, Malhi GS. A review on the impact of cognitive dysfunction on social, occupational, and general functional outcomes in bipolar disorder. Bipolar Disord. 2015;17:41\u201355.","journal-title":"Bipolar Disord"},{"key":"2860_CR5","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1111\/bdi.12148","volume":"16","author":"S Tse","year":"2014","unstructured":"Tse S, Chan S, Ng KL, Yatham LN. Meta-analysis of predictors of favorable employment outcomes among individuals with bipolar disorder. Bipolar Disord. 2014;16:217\u201329.","journal-title":"Bipolar Disord"},{"key":"2860_CR6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1111\/j.1468-1331.2011.03590.x","volume":"19","author":"J Olesen","year":"2012","unstructured":"Olesen J, Gustavsson A, Svensson M, Wittchen H, J\u00f6nsson B. The economic cost of brain disorders in Europe. Eur J Neurol. 2012;19:155\u201362.","journal-title":"Eur J Neurol"},{"key":"2860_CR7","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.1016\/j.euroneuro.2016.08.011","volume":"26","author":"KW Miskowiak","year":"2016","unstructured":"Miskowiak KW, Carvalho AF, Vieta E, Kessing LV. Cognitive enhancement treatments for bipolar disorder: a systematic review and methodological recommendations. Eur Neuropsychopharmacol. 2016;26:1541\u201361.","journal-title":"Eur Neuropsychopharmacol"},{"key":"2860_CR8","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1111\/bdi.12497","volume":"19","author":"K Miskowiak","year":"2017","unstructured":"Miskowiak K, Kjaerstad H, St\u00f8ttrup M, Svendsen A, Demant K, Hoeffding L, et al. The catechol-O-methyltransferase (COMT) Val158Met genotype modulates working memory-related dorsolateral prefrontal response and performance in bipolar disorder. Bipolar Disord. 2017;19:214\u201324.","journal-title":"Bipolar Disord"},{"key":"2860_CR9","volume-title":"Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force. Press","author":"KW Miskowiak","year":"2017","unstructured":"Miskowiak KW, Burdick KE, Martinez Aran A, Bonnin CM, Bowie CR, Carvalho AF, et al. Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force. Press. 2017."},{"key":"2860_CR10","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.coph.2013.11.009","volume":"14","author":"PJ Nathan","year":"2014","unstructured":"Nathan PJ, Phan KL, Harmer CJ, Mehta MA, Bullmore ET. Increasing pharmacological knowledge about human neurological and psychiatric disorders through functional neuroimaging and its application in drug discovery. Curr Opin Pharmacol. 2014;14:54\u201361.","journal-title":"Curr Opin Pharmacol"},{"key":"2860_CR11","volume-title":"Treat. Bipolar Disord. - Integr. Treat. Strateg. Future Dir","author":"KW Miskowiak","year":"2015","unstructured":"Miskowiak KW, Kessing LV. Cognitive enhancement in bipolar disorder: current evidence and methodological considerations. In: Carvalho A, Vieta E, editors. Treat. Bipolar Disord. - Integr. Treat. Strateg. Future Dir. Oxford: Oxford University Press; 2015."},{"key":"2860_CR12","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.jad.2012.04.020","volume":"142","author":"C Anaya","year":"2012","unstructured":"Anaya C, Martinez Aran A, Ayuso-Mateos JL, Wykes T, Vieta E, Scott J. A systematic review of cognitive remediation for schizo-affective and affective disorders. J Affect Disord. 2012;142:13\u201321.","journal-title":"J Affect Disord"},{"key":"2860_CR13","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s40345-017-0079-3","volume":"5","author":"J Veeh","year":"2017","unstructured":"Veeh J, Kopf J, Kittel-Schneider S, Deckert J, Reif A. Cognitive remediation for bipolar patients with objective cognitive impairment: a naturalistic study. Int J Bipolar Disord. 2017;5:8.","journal-title":"Int J Bipolar Disord"},{"issue":"9","key":"2860_CR14","doi-asserted-by":"publisher","first-page":"e1242","DOI":"10.4088\/JCP.17m11476","volume":"78","author":"KE Lewandowski","year":"2017","unstructured":"Lewandowski KE, Sperry SH, Cohen BM, Norris LA, Fitzmaurice GM, Ongur D, et al. Treatment to enhance cognition in bipolar disorder (TREC-BD): efficacy of a randomized controlled trial of cognitive remediation versus active control. J. Clin. Psychiatry. 2017;78(9):e1242\u20139.","journal-title":"J. Clin. Psychiatry."},{"key":"2860_CR15","doi-asserted-by":"publisher","first-page":"e0127955","DOI":"10.1371\/journal.pone.0127955","volume":"10","author":"KM Demant","year":"2015","unstructured":"Demant KM, Vinberg M, Kessing LV, Miskowiak KW. Effects of short-term cognitive remediation on cognitive dysfunction in partially or fully remitted individuals with bipolar disorder: results of a randomised controlled trial. PLoS One. 2015;10:e0127955.","journal-title":"PLoS One"},{"key":"2860_CR16","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.psychres.2015.05.022","volume":"229","author":"KM Demant","year":"2015","unstructured":"Demant KM, Vinberg M, Kessing LV, Miskowiak KW. Assessment of subjective and objective cognitive function in bipolar disorder: correlations, predictors and the relation to psychosocial function. Psychiatry Res. 2015;229:565\u201371.","journal-title":"Psychiatry Res"},{"key":"2860_CR17","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.jad.2015.07.039","volume":"187","author":"JH Jensen","year":"2015","unstructured":"Jensen JH, St\u00f8ttrup MM, Nayberg E, Knorr U, Ullum H, Purdon SE, et al. Optimising screening for cognitive dysfunction in bipolar disorder: validation and evaluation of objective and subjective tools. J Affect Disord. 2015;187:10\u20139.","journal-title":"J Affect Disord"},{"key":"2860_CR18","doi-asserted-by":"crossref","unstructured":"Bowie CR, Grossman M, Gupta M, Holshausen K, Best MW. Action-Based Cognitive Remediation for Individuals With Serious Mental Illnesses: Effects of Real-World Simulations and Goal Setting on Functional and Vocational Outcomes. Psychiatr Rehabil J. 2016 [cited 2016 Sep 6]; Available from: \n                    http:\/\/doi.apa.org\/getdoi.cfm?doi=10.1037\/prj0000189\n                    \n                  .","DOI":"10.1037\/prj0000189"},{"key":"2860_CR19","doi-asserted-by":"publisher","first-page":"1791","DOI":"10.1176\/appi.ajp.2007.07060906","volume":"164","author":"SR McGurk","year":"2007","unstructured":"McGurk SR, Twamley EW, Sitzer DI, McHugo GJ, Mueser KT. A meta-analysis of cognitive remediation in schizophrenia. Am J Psychiatry. 2007;164:1791\u2013802.","journal-title":"Am J Psychiatry"},{"key":"2860_CR20","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1159\/000352011","volume":"68","author":"L Cremaschi","year":"2013","unstructured":"Cremaschi L, Penzo B, Palazzo M, Dobrea C, Cristoffanini M, Dell\u2019Osso B, et al. Assessing working memory via N-back task in euthymic bipolar I disorder patients: a review of functional magnetic resonance imaging studies. Neuropsychobiology. 2013;68:63\u201370.","journal-title":"Neuropsychobiology"},{"key":"2860_CR21","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1111\/j.1399-5618.2004.00147.x","volume":"6","author":"PJ Monks","year":"2004","unstructured":"Monks PJ, Thompson JM, Bullmore ET, Suckling J, Brammer MJ, Williams SC, et al. A functional MRI study of working memory task in euthymic bipolar disorder: evidence for task-specific dysfunction. Bipolar Disord. 2004;6:550\u201364.","journal-title":"Bipolar Disord"},{"key":"2860_CR22","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1093\/schbul\/sbv025","volume":"41","author":"IS Ramsay","year":"2015","unstructured":"Ramsay IS, MacDonald AW. Brain correlates of cognitive remediation in schizophrenia: activation likelihood analysis shows preliminary evidence of neural target engagement. Schizophr Bull. 2015;41:1276\u201384.","journal-title":"Schizophr Bull"},{"key":"2860_CR23","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/acps.12597","volume":"134","author":"KW Miskowiak","year":"2016","unstructured":"Miskowiak KW, Macoveanu J, Vinberg M, Assentoft E, Randers L, Harmer CJ, et al. Effects of erythropoietin on memory-relevant neurocircuitry activity and recall in mood disorders. Acta Psychiatr Scand. 2016;134:249\u201359.","journal-title":"Acta Psychiatr Scand"},{"key":"2860_CR24","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1017\/S0033291716000209","volume":"46","author":"KW Miskowiak","year":"2016","unstructured":"Miskowiak KW, Vinberg M, Glerup L, Paulson OB, Knudsen GM, Ehrenreich H, et al. Neural correlates of improved executive function following erythropoietin treatment in mood disorders. Psychol Med. 2016;46:1679\u201391.","journal-title":"Psychol Med"},{"key":"2860_CR25","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","volume":"23","author":"M Hamilton","year":"1960","unstructured":"Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry. 1960;23:56\u201362.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2860_CR26","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1192\/bjp.133.5.429","volume":"133","author":"RC Young","year":"1978","unstructured":"Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry J Ment Sci. 1978;133:429\u201335.","journal-title":"Br J Psychiatry J Ment Sci"},{"key":"2860_CR27","doi-asserted-by":"publisher","first-page":"e015462","DOI":"10.1136\/bmjopen-2016-015462","volume":"7","author":"LV Kessing","year":"2017","unstructured":"Kessing LV, Munkholm K, Faurholt-Jepsen M, Miskowiak KW, Nielsen LB, Frikke-Schmidt R, et al. The bipolar illness onset study: research protocol for the BIO cohort study. BMJ Open. 2017;7:e015462.","journal-title":"BMJ Open"},{"key":"2860_CR28","volume-title":"The Screen for Cognitive Impairment in Psychiatry: Administration and Psychometric Properties","author":"SE Purdon","year":"2005","unstructured":"Purdon SE. The Screen for Cognitive Impairment in Psychiatry: Administration and Psychometric Properties. Edmonton: PNL, Inc.; 2005."},{"key":"2860_CR29","first-page":"589","volume":"47","author":"JK Wing","year":"1990","unstructured":"Wing JK, Babor T, Brugha T, Burke J, Cooper JE, Giel R, et al. SCAN. Schedules for clinical assessment in neuropsychiatry. Arch. Gen. Psychiatry. 1990;47:589\u201393.","journal-title":"Psychiatry"},{"key":"2860_CR30","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1001\/archpsyc.60.4.402","volume":"60","author":"F Colom","year":"2003","unstructured":"Colom F, Vieta E, Martinez-Aran A, Reinares M, Goikolea JM, Benabarre A, et al. A randomized trial on the efficacy of group psychoeducation in the prophylaxis of recurrences in bipolar patients whose disease is in remission. Arch Gen Psychiatry. 2003;60:402\u20137.","journal-title":"Arch Gen Psychiatry"},{"key":"2860_CR31","unstructured":"Schmidt M. Rey auditory verbal learning test: a handbook [Internet]. Western Psychological Services Los Angeles; 1996 [cited 2016 May 29]. Available from: \n                    http:\/\/v-psyche.com\/doc\/Clinical%20Test\/Rey%20Auditory%20Verbal%20Learning%20Test.docx\n                    \n                  ."},{"key":"2860_CR32","volume-title":"RBANS manual: repeatable battery for the assessment of neuropsychological status","author":"C Randolph","year":"1998","unstructured":"Randolph C. RBANS manual: repeatable battery for the assessment of neuropsychological status. San Antonio: The Psychological Corporation; 1998."},{"key":"2860_CR33","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/0028-3932(67)90015-2","volume":"5","author":"JG Borkowski","year":"1967","unstructured":"Borkowski JG, Benton AL, Spreen O. Word fluency and brain damage. Neuropsychologia. 1967;5:135\u201340.","journal-title":"Neuropsychologia"},{"key":"2860_CR34","volume-title":"Wechsler Adult Intelligence Scale-III","author":"D Wechsler","year":"1997","unstructured":"Wechsler D. Wechsler Adult Intelligence Scale-III. San Antonio: The Psychological Corporation; 1997."},{"key":"2860_CR35","volume-title":"Manual of directions and scoring","author":"Army Individual Test Battery","year":"1944","unstructured":"Army Individual Test Battery. Manual of directions and scoring. Washington, DC: War Department, Adjutant General\u2019s Office; 1944."},{"key":"2860_CR36","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1745-0179-3-5","volume":"3","author":"AR Rosa","year":"2007","unstructured":"Rosa AR, S\u00e1nchez-Moreno J, Mart\u00ednez-Aran A, Salamero M, Torrent C, Reinares M, et al. Validity and reliability of the functioning assessment short test (FAST) in bipolar disorder. Clin Pract Epidemiol Ment Health. 2007;3:5.","journal-title":"Clin Pract Epidemiol Ment Health"},{"key":"2860_CR37","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1093\/oxfordjournals.schbul.a006870","volume":"27","author":"TL Patterson","year":"2001","unstructured":"Patterson TL, Goldman S, McKibbin CL, Hughs T, Jeste DV. UCSD performance-based skills assessment: development of a new measure of everyday functioning for severely mentally ill adults. Schizophr Bull. 2001;27:235\u201345.","journal-title":"Schizophr Bull"},{"key":"2860_CR38","doi-asserted-by":"crossref","unstructured":"Vesterager L, Christensen T\u00d8, Olsen BB, Krarup G, Forchhammer HB, Melau M, et al. Cognitive training plus a comprehensive psychosocial programme (OPUS) versus the comprehensive psychosocial programme alone for patients with first-episode schizophrenia (the NEUROCOM trial): A study protocol for a centrally randomised, observer-blinded multi-centre clinical trial. Trials [Internet]. 2011 [cited 2016 Sep 21];12. Available from: \n                    http:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/1745-6215-12-35\n                    \n                  .","DOI":"10.1186\/1745-6215-12-35"},{"key":"2860_CR39","volume-title":"The anxiety disease","author":"DV Sheehan","year":"1983","unstructured":"Sheehan DV. The anxiety disease. New York: Charles Scribner\u2019s Sons; 1983."},{"key":"2860_CR40","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1023\/A:1008815005736","volume":"8","author":"G Hawthorne","year":"1999","unstructured":"Hawthorne G, Richardson J, Osborne R. The assessment of quality of life (AQoL) instrument: a psychometric measure of health-related quality of life. Qual Life Res Int J Qual Life Asp Treat Care Rehabil. 1999;8:209\u201324.","journal-title":"Qual Life Res Int J Qual Life Asp Treat Care Rehabil"},{"key":"2860_CR41","doi-asserted-by":"crossref","unstructured":"Group TW. The Development of the World Health Organization Quality of Life Assessment Instrument (the WHOQOL). In: M.D JO, D WKP, editors. Qual. Life Assess. Int. Perspect. [Internet]. Springer Berlin Heidelberg; 1994 [cited 2015 Dec 24]. p. 41\u201357. Available from: \n                    http:\/\/link.springer.com.ep.fjernadgang.kb.dk\/chapter\/10.1007\/978-3-642-79123-9_4\n                    \n                  .","DOI":"10.1007\/978-3-642-79123-9_4"},{"key":"2860_CR42","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jad.2013.02.022","volume":"150","author":"AR Rosa","year":"2013","unstructured":"Rosa AR, Mercad\u00e9 C, S\u00e1nchez-Moreno J, Sol\u00e9 B, Mar Bonnin CD, Torrent C, et al. Validity and reliability of a rating scale on subjective cognitive deficits in bipolar disorder (COBRA). J Affect Disord. 2013;150:29\u201336.","journal-title":"J Affect Disord"},{"key":"2860_CR43","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1192\/bjp.180.5.461","volume":"180","author":"JC Mundt","year":"2002","unstructured":"Mundt JC, Marks IM, Shear MK, Greist JM. The work and social adjustment scale: a simple measure of impairment in functioning. Br J Psychiatry. 2002;180:461\u20134.","journal-title":"Br J Psychiatry"},{"issue":"8","key":"2860_CR44","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1111\/bdi.12534","volume":"19","author":"KW Miskowiak","year":"2017","unstructured":"Miskowiak KW, Burdick KE, Martinez-Aran A, Bonnin CM, Bowie CR, Carvalho AF, et al. Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force. Bipolar Disord. 2017;19(8):614\u201326.","journal-title":"Bipolar Disord"},{"key":"2860_CR45","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.bbi.2011.07.239","volume":"26","author":"HH Chang","year":"2012","unstructured":"Chang HH, Lee IH, Gean PW, Lee S-Y, Chi MH, Yang YK, et al. Treatment response and cognitive impairment in major depression: association with C-reactive protein. Brain Behav Immun. 2012;26:90\u20135.","journal-title":"Brain Behav Immun"},{"key":"2860_CR46","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.jad.2013.04.039","volume":"150","author":"F Dickerson","year":"2013","unstructured":"Dickerson F, Stallings C, Origoni A, Vaughan C, Khushalani S, Yolken R. Elevated C-reactive protein and cognitive deficits in individuals with bipolar disorder. J Affect Disord. 2013;150:456\u20139.","journal-title":"J Affect Disord"},{"key":"2860_CR47","first-page":"540","volume":"4","author":"R Grassi-Oliveira","year":"2011","unstructured":"Grassi-Oliveira R, Bauer ME, Pezzi JC, Teixeira AL, Brietzke E. Interleukin-6 and verbal memory in recurrent major depressive disorder. Neuro Endocrinol Lett. 2011;4:540\u20134.","journal-title":"Neuro Endocrinol Lett"},{"key":"2860_CR48","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.jad.2015.08.058","volume":"188","author":"JD Rosenblat","year":"2015","unstructured":"Rosenblat JD, Brietzke E, Mansur RB, Maruschak NA, Lee Y, McIntyre RS. Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: evidence, pathophysiology and treatment implications. J Affect Disord. 2015;188:149\u201359.","journal-title":"J Affect Disord"},{"key":"2860_CR49","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1016\/j.psychres.2015.05.078","volume":"228","author":"V Uyanik","year":"2015","unstructured":"Uyanik V, Tuglu C, Gorgulu Y, Kunduracilar H, Uyanik MS. Assessment of cytokine levels and hs-CRP in bipolar I disorder before and after treatment. Psychiatry Res. 2015;228:386\u201392.","journal-title":"Psychiatry Res"},{"key":"2860_CR50","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1016\/j.euroneuro.2016.05.009","volume":"26","author":"CV Ott","year":"2016","unstructured":"Ott CV, Vinberg M, Kessing LV, Miskowiak KW. The effect of erythropoietin on cognition in affective disorders \u2013 associations with baseline deficits and change in subjective cognitive complaints. Eur Neuropsychopharmacol. 2016;26:1264\u201373.","journal-title":"Eur Neuropsychopharmacol"}],"updated-by":[{"DOI":"10.1186\/s13063-019-3289-4","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T00:00:00Z","timestamp":1554681600000}}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-018-2860-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13063-018-2860-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-018-2860-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T14:43:57Z","timestamp":1569163437000},"score":1,"resource":{"primary":{"URL":"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-018-2860-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,12]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["2860"],"URL":"https:\/\/doi.org\/10.1186\/s13063-018-2860-8","relation":{},"ISSN":["1745-6215"],"issn-type":[{"value":"1745-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,12]]},"assertion":[{"value":"2 October 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2019","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Following publication of the original article [1], the authors notified us that a comment in the <b>Peripheral and neural biomarkers and genotype section<\/b> was incorrectly phrased during editing. \u201c4 weeks of treatment (four active ABCR sessions twice a week or control group sessions twice a week)\u201d should have actually been described as \u201c4 weeks of treatment (4 active, twice a week, ABCR sessions or 2 weekly control group sessions)\u201d.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study has been approved by the Ethics Committee in the Capital Region of Denmark (protocol H-16043480) and the Danish Data Protection Agency (2012-58-0004). It was retrospectively registered at\n                      \n                      (NCT03295305) on 26 September 2017 (\n                      \n                      ). Written informed consent will be obtained from all participants. Any important changes in the protocol will be reported to the Ethics Committee in the Capital Region of Denmark and the Danish Data Protection Agency.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"KWM has received consultant fees from H. Lundbeck and Allergan. MV has received consultancy fees from H. Lundbeck and Astra Zeneca within the last 3 years. LVK has been a consultant for H. Lundbeck, AstraZeneca, and Sunovion within the last 3 years. EMC has received honoraria from H. Lundbeck within the last 3 years. CRB has received honoraria from Boehringer Ingelheim, Lundbeck, Otsuka, and Abbie. CVO has no competing interests. GMK has not received any honoraria from pharmaceutical companies within the last 3\u00a0years. The computer software used in the ABCR group is provided free of charge by HappyNeuron Pro (\n                      \n                      ).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"487"}}