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The trial will be conducted according to the principles of ICH-GCP and appropriate legal regulations. Professional Code for Physicians in Germany and Declaration of Helsinki in its actual version will be adhered to. All participants and their parents will need to sign an informed consent document with details about the study including its purpose, duration, procedures, and key contacts, as well as risks and potential benefits. At any time, participants or parents may withdraw their consent for any reason without any negative consequences regarding their treatment.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Prof. Holtmann served in an advisory role for Shire and Medice and received conference attendance support or was paid for public speaking by Lilly, Medice, Neuroconn, and Shire. He receives research support from the German Research Foundation and the German Ministry of Education and Research. He receives royalties as editor in chief of the German Journal for Child and Adolescent Psychiatry and for text books from Hogrefe. Prof. Legenbauer received conference attendance support from Lilly as well as royalties for text books from Hogrefe and Springer as well as research support from the German Ministry of Education and Research, the European Union (Department of Justice), the Swiss anorexia nervosa foundation (SANS) and the FORUM Institute of the Ruhr-University Bochum. Prof. Koelch received research support from the German Ministry of Education and Research, German Ministry of Health, German Ministry for Families, Women, Seniors and Youth, Swiss Office for Justice; he receives royalties for books or chapters in books by Hogrefe, Springer, and Beltz. Prof. Plener received speaker honorarium from Shire and royalties from text books by Hogrefe and Springer. Within the last five years he received research support from The German Federal Ministry of Education and Research (BMBF), the German Federal Institute for Drugs and Medical Devices (BfArM), the VW Foundation, the Baden-Wuerttemberg Foundation, the Foundation for outpatient child and adolescent psychiatry, Servier, and Lundbeck. Prof. Schulte-Markwort received research support of BMBF, innovation foundation, and conference attendance support by Medice.The present work is unrelated to the above grants and relationships. The other authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"568"}}