{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T23:07:47Z","timestamp":1765667267999,"version":"3.37.3"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T00:00:00Z","timestamp":1563494400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T00:00:00Z","timestamp":1563494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009776","name":"McMaster University","doi-asserted-by":"publisher","award":["McMaster Surgical Associates Grant"],"award-info":[{"award-number":["McMaster Surgical Associates Grant"]}],"id":[{"id":"10.13039\/100009776","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s13063-019-3536-8","type":"journal-article","created":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T15:02:47Z","timestamp":1563548567000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Development of the IRIS-AR strategy: an intervention to improve rates of accrual and retention for the VTE-PRO randomized controlled trial"],"prefix":"10.1186","volume":"20","author":[{"given":"Christine","family":"Fahim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Hylton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marko","family":"Simunovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Agzarian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Finley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wael C.","family":"Hanna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaron","family":"Shargall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,7,19]]},"reference":[{"issue":"11","key":"3536_CR1","doi-asserted-by":"publisher","first-page":"e1000368","DOI":"10.1371\/journal.pmed.1000368","volume":"7","author":"Patrina H. Y. Caldwell","year":"2010","unstructured":"Caldwell PHY, Hamilton S, Tan A, Craig JC. Strategies for increasing recruitment to randomized controlled trials: systematic review. PLoS Med. 2010. \n                    https:\/\/doi.org\/10.1371\/journal.pmed.1000368\n                    \n                  .","journal-title":"PLoS Medicine"},{"key":"3536_CR2","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1200\/JCO.2001.19.6.1728","volume":"19","author":"PN Lara","year":"2001","unstructured":"Lara PN, Higdon R, Lim N, et al. Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrolment. J Clin Oncol. 2001;19:1728\u201333.","journal-title":"J Clin Oncol"},{"issue":"1","key":"3536_CR3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1055\/s-0030-1267080","volume":"2","author":"JR Dettori","year":"2011","unstructured":"Dettori JR. Loss to follow-up. Evid Based Spine Care J. 2011;2(1):7\u201310.","journal-title":"Evid Based Spine Care J"},{"key":"3536_CR4","doi-asserted-by":"publisher","first-page":"e002360","DOI":"10.1136\/bmjopen-2012-002360","volume":"3","author":"S Treweek","year":"2013","unstructured":"Treweek S, Lockhart P, Pitkethly M, Cook JA, et al. Methods to improve recruitment to randomized controlled trials: Cochrane systematic review and meta-analysis. BMJ Open. 2013;3:e002360.","journal-title":"BMJ Open"},{"key":"3536_CR5","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/j.vaccine.2009.10.081","volume":"28","author":"I Ridda","year":"2010","unstructured":"Ridda I, MacIntyre CR, Lindley RI, Tan TC. Difficulties in recruiting older people in clinical trials: an examination of barriers and solutions. Vaccine. 2010;28:901\u20136.","journal-title":"Vaccine"},{"issue":"5","key":"3536_CR6","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1002\/cncr.27854","volume":"119","author":"D Hui","year":"2013","unstructured":"Hui D, Glitza I, Chrisholm G, Yennu S, et al. Attrition rates, reasons, and predictive factors in supportive care and palliative oncology clinical trials. Cancer. 2013;119(5):1098\u2013105.","journal-title":"Cancer"},{"key":"3536_CR7","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1017\/S1478951508000424","volume":"6","author":"P Schofield","year":"2008","unstructured":"Schofield P, Ugalde A, Carey M, Mileshkin L, et al. Lung cancer: challenges and solutions for supportive care intervention research. Palliat Support Care. 2008;6:281\u20137.","journal-title":"Palliat Support Care"},{"issue":"3","key":"3536_CR8","first-page":"205","volume":"53","author":"A Thoma","year":"2010","unstructured":"Thoma A, Farrokhyar F, McKnight L, Bhandari M. How to optimize patient recruitment. Can J Surg. 2010;53(3):205\u201310.","journal-title":"Can J Surg"},{"issue":"12","key":"3536_CR9","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/S0895-4356(99)00141-9","volume":"52","author":"S Ross","year":"1999","unstructured":"Ross S, Grant A, Counsell C, Gillespie W, et al. Barriers to participation in randomized controlled trials: a systematic review. J Clin Epidemiol. 1999;52(12):1143\u201356.","journal-title":"J Clin Epidemiol"},{"key":"3536_CR10","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S1470-2045(06)70576-9","volume":"7","author":"EJ Mills","year":"2006","unstructured":"Mills EJ, Seely D, Rachlis B, Griffith L, et al. Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors. Lancet Oncol. 2006;7:141\u20138.","journal-title":"Lancet Oncol"},{"issue":"4","key":"3536_CR11","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1111\/j.1464-0597.2008.00341.x","volume":"57","author":"S Michie","year":"2008","unstructured":"Michie S, Johnson M, Francis J, Hardeman W, Eccles M. From theory to intervention: mapping theoretically derived behavioural determinants to behaviour change techniques. Appl Psychol. 2008;57(4):660\u201380.","journal-title":"Appl Psychol"},{"key":"3536_CR12","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/1748-5908-7-37","volume":"7","author":"J Cane","year":"2012","unstructured":"Cane J, O\u2019Connor D, Michie S. Validation of the theoretical domains framework for use in behaviour change and implementation research. Implement Sci. 2012;7:37.","journal-title":"Implement Sci"},{"key":"3536_CR13","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1748-5908-6-42","volume":"6","author":"S Michie","year":"2011","unstructured":"Michie S, van Stralen MM, West R. The behaviour change wheel: a new method for characterising and designing behaviour change interventions. Implement Sci. 2011;6:42.","journal-title":"Implement Sci"},{"key":"3536_CR14","doi-asserted-by":"crossref","unstructured":"Straus S, Tetroe J, Graham ID. Knowledge translation in health care: moving from evidence to practice. 2nd ed: Wiley\/ BMJ Books; 2013.","DOI":"10.1002\/9781118413555"},{"key":"3536_CR15","doi-asserted-by":"crossref","unstructured":"Gagliardi AR, Berta W, Kothari A, Boyko J, Urquhart R. Integrated knowledge translation (IKT) in health care: a scoping review. Implement Sci. 2016;11(38).","DOI":"10.1186\/s13012-016-0399-1"},{"key":"3536_CR16","unstructured":"Extended Low-Molecular Weight Heparin VTE Prophylaxis in Thoracic Surgery. ClinicalTrials.gov Identifier: NCT02334007. Available at: \n                    https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02334007\n                    \n                  . Accessed 11 July 2019."},{"key":"3536_CR17","first-page":"341","volume":"46","author":"JF Azorin","year":"1997","unstructured":"Azorin JF, Regnard JF, Dahan M, et al. Efficacy and tolerability of fraxiparine in the prevention of thromboembolic complications in oncologic thoracic surgery. Ann Cardio Angeiol (Paris). 1997;46:341\u20137.","journal-title":"Ann Cardio Angeiol (Paris)"},{"key":"3536_CR18","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1056\/NEJMoa012385","volume":"346","author":"D Bergqvist","year":"2002","unstructured":"Bergqvist D, Agnelli G, Cohen AT, et al. Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer. N Engl J Med. 2002;346:975\u201380.","journal-title":"N Engl J Med"},{"issue":"1","key":"3536_CR19","doi-asserted-by":"publisher","first-page":"80","DOI":"10.21037\/jtd.2017.01.38","volume":"9","author":"J Agzarian","year":"2017","unstructured":"Agzarian J, Linkins L-A, Schneider L, Hanna WC, et al. Practice patterns in venous thromboembolism (VTE) prophylaxis in thoracic surgery: a comprehensive Canadian Delphi study. J Thorac Dis. 2017;9(1):80\u20137.","journal-title":"J Thorac Dis"},{"issue":"1","key":"3536_CR20","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1002\/chp.47","volume":"26","author":"ID Graham","year":"2006","unstructured":"Graham ID, Logan J, Harrison MB, Straus SE, et al. Lost in knowledge translation: time for a map? J Contin Educ Heal Prof. 2006;26(1):13\u201324.","journal-title":"J Contin Educ Heal Prof"},{"key":"3536_CR21","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/1748-5908-8-111","volume":"23","author":"J Dyson","year":"2013","unstructured":"Dyson J, Lawton R, Jackson C, Cheater F. Development of a theory-based instrument to identify barriers and levers to best hand hygiene practice among healthcare practitioners. Implement Sci. 2013;23:111.","journal-title":"Implement Sci"},{"key":"3536_CR22","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/1748-5908-7-52","volume":"7","author":"AM Patey","year":"2012","unstructured":"Patey AM, Islam R, Francis JJ, Bryson GL, Grimshaw J, the Canada PRIME Plus Team. Anesthesiologists\u2019 and surgeons\u2019 perceptions about routine preoperative testing in low-risk patients: application of the Theoretical Domains 77 Framework (TDF) to identify factors that influence physicians\u2019 decisions to order pre-operative tests. Implement Sci. 2012;7:52.","journal-title":"Implement Sci"},{"issue":"1","key":"3536_CR23","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1186\/1748-5908-7-93","volume":"7","author":"R Islam","year":"2012","unstructured":"Islam R, Tinmouth AT, Francis JJ, Brehaut JC, Born J, Stockton C, et al. A cross-country comparison of intensive care physicians\u2019 beliefs about their transfusion behaviour: a qualitative study using the theoretical domains framework. Implement Sci. 2012;7(1):93.","journal-title":"Implement Sci"},{"issue":"4","key":"3536_CR24","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1348\/135910708X397025","volume":"14","author":"JJ Francis","year":"2009","unstructured":"Francis JJ, Stockton C, Eccles MP, Johnston M, Cuthbertson BH, Grimshaw JM, et al. Evidence-based selection of theories for designing behaviour change interventions: using methods based on theoretical construct domains to understand clinicians\u2019 blood transfusion behaviour. Br J Health Psychol. 2009;14(4):625\u201346.","journal-title":"Br J Health Psychol"},{"issue":"1","key":"3536_CR25","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/s13012-017-0605-9","volume":"12","author":"L Atkins","year":"2017","unstructured":"Atkins L, Francis J, Islam R, O\u2019Connor D, Patey A, Ivers N, Foy R, Duncan EM, Colquhoun H, Grimshaw JM, Lawton R. A guide to using the Theoretical Domains Framework of behaviour change to investigate implementation problems. Implement Sci. 2017;12(1):77.","journal-title":"Implement Sci"},{"key":"3536_CR26","unstructured":"Creswell JW. Qualitative inquiry and research design: choosing among five traditions. Thousand Oaks: Sage Publications, Inc.; 1998."},{"issue":"1","key":"3536_CR27","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1177\/104973200129118183","volume":"10","author":"JM Morse","year":"2000","unstructured":"Morse JM. Determining sample size. Qual Health Res. 2000;10(1):3\u20135.","journal-title":"Qual Health Res"},{"issue":"10","key":"3536_CR28","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1080\/08870440903194015","volume":"25","author":"JJ Francis","year":"2010","unstructured":"Francis JJ, Johnston M, Robertson C, Glidwell L, Entwistle V, Eccles MP, et al. What is an adequate sample size? Operationalising data saturation for theory-based interview studies. Psychol Health. 2010;25(10):1229\u201345.","journal-title":"Psychol Health"},{"issue":"2","key":"3536_CR29","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1053\/j.semtcvs.2015.12.003","volume":"28","author":"Y Shargall","year":"2016","unstructured":"Shargall Y, Hanna WC, Schneider L, et al. The Integrated Comprehensive Care Program: a novel home care initiative after major thoracic surgery. Semin Thorac Cardiovasc Surg. 2016;28(2):574\u201382.","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"3536_CR30","doi-asserted-by":"publisher","first-page":"164S","DOI":"10.1016\/S0197-2456(00)00074-X","volume":"21","author":"WJ Rejeski","year":"2000","unstructured":"Rejeski WJ, Brawley LR, McAuley E, Rapp S. An examination of theory and behavior change in randomized clinical trials. Control Clin Trials. 2000;21:164S\u201370S.","journal-title":"Control Clin Trials"},{"issue":"14","key":"3536_CR31","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/1472-6963-14-89","volume":"26","author":"JP Domecq","year":"2014","unstructured":"Domecq JP, Prutsky G, Elraiyah T, Wang Z, et al. Patient engagement in research: a systematic review. BMC Health Serv Res. 2014;26(14):89.","journal-title":"BMC Health Serv Res"},{"key":"3536_CR32","doi-asserted-by":"publisher","unstructured":"Stensland KD, McBride RB, Latif A, Wisnivesky J, et al. Adult cancer clinical trials that fail to complete: an epidemic? J Natl Cancer Inst. 2014;106(9). \n                    https:\/\/doi.org\/10.1093\/jnci\/dju229\n                    \n                  .","DOI":"10.1093\/jnci\/dju229"},{"key":"3536_CR33","volume-title":"Evidence-based medicine: how to practice and teach EBM","author":"DL Sacket","year":"1997","unstructured":"Sacket DL, Richardson WS, Rosenberg W. Evidence-based medicine: how to practice and teach EBM. New York: Churchill Livingstone; 1997."},{"issue":"5","key":"3536_CR34","doi-asserted-by":"publisher","first-page":"e0127242","DOI":"10.1371\/journal.pone.0127242","volume":"10","author":"RJ Williams","year":"2015","unstructured":"Williams RJ, Tse T, DiPiazza K, Zarin DA. Terminated trials in the ClinicalTrials.gov results database: evaluation of availability of primary outcome data and reasons for termination. PLoS One. 2015;10(5):e0127242.","journal-title":"PLoS One"},{"issue":"2","key":"3536_CR35","doi-asserted-by":"publisher","first-page":"e003821","DOI":"10.1136\/bmjopen-2013-003821","volume":"4","author":"VC Brueton","year":"2014","unstructured":"Brueton VC, Tierney JF, Stenning S, Merideth S, et al. Strategies to improve retention in randomized trials: a Cochrane systematic review and meta analysis. BMJ Open. 2014;4(2):e003821.","journal-title":"BMJ Open"},{"issue":"8","key":"3536_CR36","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.jclinepi.2006.11.023","volume":"60","author":"KA Robinson","year":"2007","unstructured":"Robinson KA, Dennison CR, Wayman DM, Pronovost PJ, Needham DM. Systematic review identifies number of strategies important for retaining study participants. J Clin Epidemiol. 2007;60(8):757\u201365.","journal-title":"J Clin Epidemiol"},{"issue":"8","key":"3536_CR37","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1097\/00005650-199808000-00004","volume":"36","author":"DL Roter","year":"1998","unstructured":"Roter DL, Hall JA, Merisca R, Nordstrom B, et al. Effectiveness of interventions to improve patient compliance: a meta-analysis. Med Care. 1998;36(8):1138\u201361.","journal-title":"Med Care"}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-019-3536-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13063-019-3536-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-019-3536-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T23:13:53Z","timestamp":1595027633000},"score":1,"resource":{"primary":{"URL":"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-019-3536-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,19]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["3536"],"URL":"https:\/\/doi.org\/10.1186\/s13063-019-3536-8","relation":{},"ISSN":["1745-6215"],"issn-type":[{"type":"electronic","value":"1745-6215"}],"subject":[],"published":{"date-parts":[[2019,7,19]]},"assertion":[{"value":"12 March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethics approval was granted through the Hamilton Integrated Review Ethics Board (HiREB). All interview participants consented to participate.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests. This study was presented at the Academy Health D&I conference, Washington DC, December 3\u20135.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"447"}}