{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T01:32:29Z","timestamp":1789263149628,"version":"build-2803163510"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:00:00Z","timestamp":1565654400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:00:00Z","timestamp":1565654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010572","name":"Deutsche Kniegesellschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010572","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s13063-019-3610-2","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T12:03:08Z","timestamp":1565697788000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Effectiveness of a home-based re-injury prevention program on motor control, return to sport and recurrence rates after anterior cruciate ligament reconstruction: study protocol for a multicenter, single-blind, randomized controlled trial (PReP)"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7690-5418","authenticated-orcid":false,"given":"Daniel","family":"Niederer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Achtnich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Akoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atesch","family":"Ateschrang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winfried","family":"Banzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Bari\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Best","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andree","family":"Ellermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Guenther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirco","family":"Herbort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"H\u00f6her","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Janko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias M.","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Krause","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolf","family":"Petersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Stoffels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelie","family":"St\u00f6hr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Welsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Stein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,8,13]]},"reference":[{"key":"3610_CR1","doi-asserted-by":"publisher","first-page":"2226","DOI":"10.1111\/sms.13245","volume":"28","author":"D Niederer","year":"2018","unstructured":"Niederer D, Engeroff T, Wilke J, Vogt L, Banzer W. Return to play, performance and career duration after ACL rupture: a case-control study in Europe\u2019s biggest football nation. Scand J Med Sci Sports. 2018;28:2226\u201333. https:\/\/doi.org\/10.1111\/sms.13245 .","journal-title":"Scand J Med Sci Sports"},{"key":"3610_CR2","doi-asserted-by":"publisher","first-page":"1861","DOI":"10.1177\/0363546515621554","volume":"44","author":"AJ Wiggins","year":"2016","unstructured":"Wiggins AJ, Grandhi RK, Schneider DK, Stanfield D, Webster KE, Myer GD. Risk of secondary injury in younger athletes after anterior cruciate ligament reconstruction: a systematic review and meta-analysis. Am J Sports Med. 2016;44:1861\u201376. https:\/\/doi.org\/10.1177\/0363546515621554 .","journal-title":"Am J Sports Med"},{"key":"3610_CR3","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1097\/00005768-200207000-00025","volume":"34","author":"SA Herring","year":"2002","unstructured":"Herring SA, Bergfeld JA, Boyd J. The team physician and return-to-play issues: a consensus statement. Med Sci Sports Exerc. 2002;34:1212\u20134.","journal-title":"Med Sci Sports Exerc"},{"key":"3610_CR4","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1136\/bjsports-2015-095908","volume":"50","author":"P Kyritsis","year":"2016","unstructured":"Kyritsis P, Bahr R, Landreau P, Miladi R, Witvrouw E. Likelihood of ACL graft rupture: not meeting six clinical discharge criteria before return to sport is associated with a four times greater risk of rupture. Br J Sports Med. 2016;50:946\u201351. https:\/\/doi.org\/10.1136\/bjsports-2015-095908 .","journal-title":"Br J Sports Med"},{"key":"3610_CR5","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1136\/bjsports-2016-096031","volume":"50","author":"H Grindem","year":"2016","unstructured":"Grindem H, Snyder-Mackler L, Moksnes H, Engebretsen L, Risberg MA. Simple decision rules can reduce reinjury risk by 84% after ACL reconstruction: The Delaware-Oslo ACL cohort study. Br J Sports Med. 2016;50:804\u20138. https:\/\/doi.org\/10.1136\/bjsports-2016-096031 .","journal-title":"Br J Sports Med"},{"key":"3610_CR6","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1177\/0363546512459638","volume":"41","author":"TE Hewett","year":"2013","unstructured":"Hewett TE, Di Stasi SL, Myer GD. Current concepts for injury prevention in athletes after anterior cruciate ligament reconstruction. Am J Sports Med. 2013;41:216\u201324. https:\/\/doi.org\/10.1177\/0363546512459638 .","journal-title":"Am J Sports Med"},{"key":"3610_CR7","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1016\/j.arthro.2011.09.009","volume":"27","author":"SD Barber-Westin","year":"2011","unstructured":"Barber-Westin SD, Noyes FR. Factors used to determine return to unrestricted sports activities after anterior cruciate ligament reconstruction. Arthroscopy. 2011;27:1697\u2013705. https:\/\/doi.org\/10.1016\/j.arthro.2011.09.009 .","journal-title":"Arthroscopy"},{"key":"3610_CR8","doi-asserted-by":"publisher","first-page":"100","DOI":"10.3810\/psm.2011.09.1926","volume":"39","author":"SD Barber-Westin","year":"2011","unstructured":"Barber-Westin SD, Noyes FR. Objective criteria for return to athletics after anterior cruciate ligament reconstruction and subsequent reinjury rates: a systematic review. Phys Sportsmed. 2011;39:100\u201310. https:\/\/doi.org\/10.3810\/psm.2011.09.1926 .","journal-title":"Phys Sportsmed"},{"key":"3610_CR9","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.1007\/s40279-018-0942-0","volume":"48","author":"PT Johnston","year":"2018","unstructured":"Johnston PT, McClelland JA, Webster KE. Lower limb biomechanics during single-leg landings following anterior cruciate ligament reconstruction: a systematic review and meta-analysis. Sports Med. 2018;48:2103\u201326. https:\/\/doi.org\/10.1007\/s40279-018-0942-0 .","journal-title":"Sports Med"},{"key":"3610_CR10","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1007\/s40279-017-0674-6","volume":"47","author":"B Dingenen","year":"2017","unstructured":"Dingenen B, Gokeler A. Optimization of the Return-to-Sport paradigm after anterior cruciate ligament reconstruction: a critical step back to move forward. Sports Med. 2017;47:1487\u2013500. https:\/\/doi.org\/10.1007\/s40279-017-0674-6 .","journal-title":"Sports Med"},{"key":"3610_CR11","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/s12178-017-9416-5","volume":"10","author":"T Nessler","year":"2017","unstructured":"Nessler T, Denney L, Sampley J. ACL injury prevention: what does research tell us? Curr Rev Musculoskelet Med. 2017;10:281\u20138. https:\/\/doi.org\/10.1007\/s12178-017-9416-5 .","journal-title":"Curr Rev Musculoskelet Med"},{"key":"3610_CR12","first-page":"44","volume":"11","author":"NJ Chimera","year":"2016","unstructured":"Chimera NJ, Kremer K. Sportsmetrics training improves power and landing in high school rowers. Int J Sports Phys Ther. 2016;11:44\u201353.","journal-title":"Int J Sports Phys Ther"},{"key":"3610_CR13","doi-asserted-by":"publisher","first-page":"e0144063","DOI":"10.1371\/journal.pone.0144063","volume":"10","author":"LA Donnell-Fink","year":"2015","unstructured":"Donnell-Fink LA, Klara K, Collins JE, Yang HY, Goczalk MG, Katz JN, Losina E. Effectiveness of knee injury and anterior cruciate ligament tear prevention programs: a meta-analysis. PLoS One. 2015;10:e0144063. https:\/\/doi.org\/10.1371\/journal.pone.0144063 .","journal-title":"PLoS One"},{"key":"3610_CR14","unstructured":"Petersen W, Diermeier T, Mehl J, St\u00f6hr A, Ellermann A, M\u00fcller P, et al. Pr\u00e4vention von Knieverletzungen und VKB-Rupturen - Empfehlungen des DKG Komitees Ligamentverletzungen: OUP; 2016. p. 542\u201350."},{"key":"3610_CR15","doi-asserted-by":"publisher","unstructured":"Finkbiner MJ, Gaina KM, McRandall MC, Wolf MM, Pardo VM, Reid K, et al. Video Movement Analysis using Smartphones (ViMAS): a pilot study. J Vis Exp. 2017. https:\/\/doi.org\/10.3791\/54659 .","DOI":"10.3791\/54659"},{"key":"3610_CR16","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1177\/0363546505282619","volume":"34","author":"TE Hewett","year":"2005","unstructured":"Hewett TE. Anterior cruciate ligament injuries in female athletes: Part 2, A meta-analysis of neuromuscular interventions aimed at injury prevention. Am J Sports Med. 2005;34:490\u20138. https:\/\/doi.org\/10.1177\/0363546505282619 .","journal-title":"Am J Sports Med"},{"key":"3610_CR17","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1080\/00913847.2016.1131107","volume":"44","author":"LH Redler","year":"2016","unstructured":"Redler LH, Watling JP, Dennis ER, Swart E, Ahmad CS. Reliability of a field-based drop vertical jump screening test for ACL injury risk assessment. Phys Sportsmed. 2016;44:46\u201352. https:\/\/doi.org\/10.1080\/00913847.2016.1131107 .","journal-title":"Phys Sportsmed"},{"key":"3610_CR18","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1055\/s-0042-100966","volume":"30","author":"M Keller","year":"2016","unstructured":"Keller M, Kurz E, Schmidtlein O, Welsch G, Anders C. Interdisziplin\u00e4re Beurteilungskriterien f\u00fcr die Rehabilitation nach Verletzungen an der unteren Extremit\u00e4t: Ein funktionsbasierter Return to Activity Algorithmus. Sportverletz Sportschaden. 2016;30:38\u201349. https:\/\/doi.org\/10.1055\/s-0042-100966 .","journal-title":"Sportverletz Sportschaden"},{"key":"3610_CR19","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.ptsp.2014.09.002","volume":"16","author":"B Kockum","year":"2015","unstructured":"Kockum B, Heijne AI-LM. Hop performance and leg muscle power in athletes: reliability of a test battery. Phys Ther Sport. 2015;16:222\u20137. https:\/\/doi.org\/10.1016\/j.ptsp.2014.09.002 .","journal-title":"Phys Ther Sport"},{"key":"3610_CR20","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1007\/s00167-016-4246-3","volume":"25","author":"A Gokeler","year":"2017","unstructured":"Gokeler A, Welling W, Zaffagnini S, Seil R, Padua D. Development of a test battery to enhance safe return to sports after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2017;25:192\u20139. https:\/\/doi.org\/10.1007\/s00167-016-4246-3 .","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"3610_CR21","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.ptsp.2007.09.003","volume":"9","author":"KE Webster","year":"2008","unstructured":"Webster KE, Feller JA, Lambros C. Development and preliminary validation of a scale to measure the psychological impact of returning to sport following anterior cruciate ligament reconstruction surgery. Phys Ther Sport. 2008;9:9\u201315. https:\/\/doi.org\/10.1016\/j.ptsp.2007.09.003 .","journal-title":"Phys Ther Sport"},{"issue":"4","key":"3610_CR22","doi-asserted-by":"publisher","first-page":"e5","DOI":"10.2106\/JBJS.RVW.17.00114","volume":"6","author":"Joel J. Gagnier","year":"2018","unstructured":"Gagnier JJ, Shen Y, Huang H. Psychometric properties of Patient-Reported Outcome Measures for use in patients with anterior cruciate ligament injuries: a systematic review. JBJS Rev. 2018. https:\/\/doi.org\/10.2106\/JBJS.RVW.17.00114 .","journal-title":"JBJS Reviews"},{"key":"3610_CR23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00003086-198509000-00007","volume":"198","author":"Y Tegner","year":"1985","unstructured":"Tegner Y, Lysholm J. Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res. 1985;198:43\u20139.","journal-title":"Clin Orthop Relat Res"},{"key":"3610_CR24","doi-asserted-by":"publisher","first-page":"2325967118S0001","DOI":"10.1177\/2325967118S00018","volume":"6","author":"W Petersen","year":"2018","unstructured":"Petersen W, Stoffels T, Achtnich A. Prevention of knee injuries and ACL ruptures Systematic review and recommendations of the German Knee Society (DKG): The Stop-X program. Orthop J Sports Med. 2018;6:2325967118S0001. https:\/\/doi.org\/10.1177\/2325967118S00018 .","journal-title":"Orthop J Sports Med"},{"key":"3610_CR25","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.orthtr.2017.09.005","volume":"33","author":"T Stoffels","year":"2017","unstructured":"Stoffels T, Achtnich A, Petersen W. Pr\u00e4vention von Knieverletzungen \u2013 besteht da Evidenz? Sports Orthop Traumatol. 2017;33:344\u201352. https:\/\/doi.org\/10.1016\/j.orthtr.2017.09.005 .","journal-title":"Sports Orthop Traumatol"},{"key":"3610_CR26","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.orthtr.2016.12.003","volume":"33","author":"W Petersen","year":"2017","unstructured":"Petersen W, Achtnich A, Diermeier T, Mehl J, Zantop T. Das instabile Kniegelenk: Diagnostik, Pr\u00e4vention und Therapie. Sports Orthop Traumatol. 2017;33:29\u201337. https:\/\/doi.org\/10.1016\/j.orthtr.2016.12.003 .","journal-title":"Sports Orthop Traumatol"},{"key":"3610_CR27","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1136\/bjsports-2015-095898","volume":"50","author":"N van Melick","year":"2016","unstructured":"van Melick N, van Cingel REH, Brooijmans F, Neeter C, van Tienen T, Hullegie W, Nijhuis-van der Sanden MWG. Evidence-based clinical practice update: practice guidelines for anterior cruciate ligament rehabilitation based on a systematic review and multidisciplinary consensus. Br J Sports Med. 2016;50:1506\u201315. https:\/\/doi.org\/10.1136\/bjsports-2015-095898 .","journal-title":"Br J Sports Med"},{"key":"3610_CR28","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.csm.2016.08.012","volume":"36","author":"KE Wilk","year":"2017","unstructured":"Wilk KE, Arrigo CA. Rehabilitation principles of the anterior cruciate ligament reconstructed knee: twelve steps for successful progression and return to play. Clin Sports Med. 2017;36:189\u2013232. https:\/\/doi.org\/10.1016\/j.csm.2016.08.012 .","journal-title":"Clin Sports Med"},{"key":"3610_CR29","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2147\/OAJSM.S72332","volume":"7","author":"J Nyland","year":"2016","unstructured":"Nyland J, Mattocks A, Kibbe S, Kalloub A, Greene JW, Caborn DNM. Anterior cruciate ligament reconstruction, rehabilitation, and return to play: 2015 update. Open Access J Sports Med. 2016;7:21\u201332. https:\/\/doi.org\/10.2147\/OAJSM.S72332 .","journal-title":"Open Access J Sports Med"},{"issue":"4","key":"3610_CR30","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1016\/j.apmr.2017.10.019","volume":"99","author":"Daniel Niederer","year":"2018","unstructured":"Niederer D, Wilke J, Vogt L, Banzer W. Return to play after injuries\u2014A survey on the helpfulness of various forms of assistance in the shared decision-making process in semi-professional athletes in Germany. Arch Phys Med Rehabil. 2017:690\u20138. https:\/\/doi.org\/10.1016\/j.apmr.2017.10.019 .","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"key":"3610_CR31","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1177\/0269215516628617","volume":"31","author":"S Alshewaier","year":"2017","unstructured":"Alshewaier S, Yeowell G, Fatoye F. The effectiveness of pre-operative exercise physiotherapy rehabilitation on the outcomes of treatment following anterior cruciate ligament injury: a systematic review. Clin Rehabil. 2017;31:34\u201344. https:\/\/doi.org\/10.1177\/0269215516628617 .","journal-title":"Clin Rehabil"}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-019-3610-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13063-019-3610-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-019-3610-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,25]],"date-time":"2022-09-25T15:39:36Z","timestamp":1664120376000},"score":1,"resource":{"primary":{"URL":"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-019-3610-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,13]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["3610"],"URL":"https:\/\/doi.org\/10.1186\/s13063-019-3610-2","relation":{},"ISSN":["1745-6215"],"issn-type":[{"value":"1745-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,13]]},"assertion":[{"value":"29 November 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Final ethical approval has been provided on 27 June 2018. (number FF104\/2017). Clinical trial registration (registration date 1 October 2018) in the German Clinical Trials Register received the identification number DRKS00015313. All participants provided their informed consent.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"495"}}