{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:40:12Z","timestamp":1787020812823,"version":"build-2736575974"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"DOI":"10.1186\/s13063-024-08440-y","type":"journal-article","created":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T05:03:56Z","timestamp":1725426236000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluating fentanyl test strips as a harm reduction strategy in rural and urban counties: study protocol for a randomized controlled trial"],"prefix":"10.1186","volume":"25","author":[{"given":"Ashley","family":"Short Mejia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soledad A.","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget","family":"Freisthler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Grella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2618-6440","authenticated-orcid":false,"given":"Nichole L.","family":"Michaels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,4]]},"reference":[{"key":"8440_CR1","unstructured":"Centers for Disease Control and Prevention. Ohio priority topic investments. Ohio overdose investment snapshot. CDC. https:\/\/www.cdc.gov\/injury\/budget-funding\/ohio-aces-and-overdose-prevention-funding.html?CDC_AAref_Val=https:\/\/www.cdc.gov\/injury\/budget\/policystatesnapshots\/ohio.html. Accessed 27 Jul 2024."},{"key":"8440_CR2","unstructured":"Centers for Disease Control and Prevention. Drug overdose mortality by state. CDC\/National Center for Health Statistics. 2021. https:\/\/www.cdc.gov\/nchs\/pressroom\/sosmap\/drug_poisoning_mortality\/drug_poisoning.htm. Accessed 27 Jul 2024."},{"key":"8440_CR3","unstructured":"Centers for Disease Control and Prevention. Preventing opioid overdoses. 2024. https:\/\/www.cdc.gov\/overdose-prevention\/prevention\/index.html. Accessed 27 Jul 2024."},{"issue":"33","key":"8440_CR4","doi-asserted-by":"publisher","first-page":"844","DOI":"10.15585\/mmwr.mm6533a3","volume":"65","author":"AB Peterson","year":"2016","unstructured":"Peterson AB, Gladden RM, Delcher C, Spies E, Garcia-Williams A, Wang Y, Halpin J, Zibbell J, McCarty CL, DeFiore-Hyrmer J, DiOrio M, Goldberger BA. Increases in fentanyl-related overdose deaths - Florida and Ohio, 2013\u20132015. MMWR Morb Mortal Wkly Rep. 2016;65(33):844\u20139. https:\/\/doi.org\/10.15585\/mmwr.mm6533a3.","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"8440_CR5","unstructured":"Hedegaard H, Mini\u00f1o AM, Warner M. Drug overdose deaths in the United States, 1999\u20132017. NCHS Data Brief. 2018(329):1-7. Hyattsville: National Center for Health Statistics. https:\/\/www.cdc.gov\/nchs\/data\/databriefs\/db329-h.pdf. Accessed 16 Jun 2024."},{"issue":"1","key":"8440_CR6","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s12954-018-0276-0","volume":"16","author":"JE Goldman","year":"2019","unstructured":"Goldman JE, Waye KM, Periera KA, Krieger MS, Yedinak JL, Marshall BDL. Perspectives on rapid fentanyl test strips as a harm reduction practice among young adults who use drugs: a qualitative study. Harm Reduct J. 2019;16(1):3.","journal-title":"Harm Reduct J"},{"issue":"1","key":"8440_CR7","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s12954-018-0213-2","volume":"15","author":"MS Krieger","year":"2018","unstructured":"Krieger MS, Yedinak JL, Buxton JA, Lysyshyn M, Bernstein E, Rich JD, Green TC, Hadland SE, Marshall BDL. High willingness to use rapid fentanyl test strips among young adults who use drugs. Harm Reduct J. 2018;15(1):7.","journal-title":"Harm Reduct J"},{"key":"8440_CR8","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.drugpo.2018.09.009","volume":"61","author":"MS Krieger","year":"2018","unstructured":"Krieger MS, Goedel WC, Buxton JA, Lysyshyn M, Bernstein E, Sherman SG, Rich JD, Hadland SE, Green TC, Marshall BDL. Use of rapid fentanyl test strips among young adults who use drugs. Int J Drug Policy. 2018;61:52\u20138.","journal-title":"Int J Drug Policy"},{"key":"8440_CR9","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.drugpo.2018.08.007","volume":"63","author":"NC Peiper","year":"2019","unstructured":"Peiper NC, Clarke SD, Vincent LB, Ciccarone D, Kral AH, Zibbell JE. Fentanyl test strips as an opioid overdose prevention strategy: findings from a syringe services program in the Southeastern United States. Int J Drug Policy. 2019;63:122\u20138.","journal-title":"Int J Drug Policy"},{"key":"8440_CR10","unstructured":"Rembert M, Betz M, Feng B, Partridge M. Taking measure of Ohio\u2019s opioid crisis. Swank program in rural-urban policy. The Ohio State University. 2017. https:\/\/cpb-us-w2.wpmucdn.com\/u.osu.edu\/dist\/2\/14548\/files\/2017\/10\/SWANK-Taking-Measure-of-Ohios-Opioid-Crisis-1vtx548.pdf. Accessed 27 Jul 2024."},{"issue":"13","key":"8440_CR11","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1001\/jama.2019.12562","volume":"322","author":"PJ Joudrey","year":"2019","unstructured":"Joudrey PJ, Edelman EJ, Wang EA. Drive times to opioid treatment programs in urban and rural counties in 5 US states. JAMA. 2019;322(13):1310\u20132.","journal-title":"JAMA"},{"key":"8440_CR12","doi-asserted-by":"publisher","unstructured":"National Research Council (US) Panel on Handling Missing Data in Clinical Trials. The prevention and treatment of missing data in clinical trials. Washington, DC: National Academies Press; 2010. https:\/\/doi.org\/10.17226\/12955.","DOI":"10.17226\/12955"},{"issue":"1","key":"8440_CR13","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1111\/add.15114","volume":"116","author":"MP Karno","year":"2021","unstructured":"Karno MP, Rawson R, Rogers B, Spear S, Grella C, Mooney LJ, Saitz R, Kagan B, Glasner S. Effect of screening, brief intervention and referral to treatment for unhealthy alcohol and other drug use in mental health treatment settings: a randomized controlled trial. Addiction. 2021;116(1):159\u201369. https:\/\/doi.org\/10.1111\/add.15114.","journal-title":"Addiction"},{"key":"8440_CR14","unstructured":"World Health Organization. Management of substance abuse: information sheet on opioid overdose. August 2018. https:\/\/www.who.int\/substance_abuse\/information-sheet\/en\/ Accessed 28 August 2024."}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-024-08440-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13063-024-08440-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13063-024-08440-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T05:10:18Z","timestamp":1725426618000},"score":1,"resource":{"primary":{"URL":"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-024-08440-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,4]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["8440"],"URL":"https:\/\/doi.org\/10.1186\/s13063-024-08440-y","relation":{},"ISSN":["1745-6215"],"issn-type":[{"value":"1745-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,4]]},"assertion":[{"value":"1 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Nationwide Children\u2019s Hospital Institutional Review Board has given ethical approval for this study (STUDY00001919). Any modifications to the study protocol are subject to approval by the IRB of record. Relevant modifications will be reported to the trial registry and other parties as necessary. Informed consent will be obtained from all study participants according to the IRB-approved study protocol. The consent process will take place on-site at the recruitment location and will be completed prior to any data collection. At the time of enrollment, a member of the research team will review the contents of the informed consent document with the potential participant and answer any questions they may have prior to obtaining written consent via e-signature or paper consent form. Consent will be documented in REDCap and a pdf file of the signed e-consent form will be emailed to the participant. If the participant does not have an email address, a paper copy will be signed and distributed to them. Paper consent forms will be used to obtain written consent in person at the time of enrollment only as necessary (e.g., due to technology failure). Participants will be able to leave the study or stop participating in study activities at any time.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"As the primary organization conducting this study and associated data analysis, Nationwide Children\u2019s Hospital is the sponsor of this research. They can be contacted at 700 Children\u2019s Drive, Columbus, OH 43205, USA; phone number: 614\u2013722-2000.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Sponsor"}}],"article-number":"587"}}