{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:45:57Z","timestamp":1789055157320,"version":"build-2803163510"},"reference-count":62,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T00:00:00Z","timestamp":1534723200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chemistry Central Journal"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s13065-018-0463-9","type":"journal-article","created":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T02:34:31Z","timestamp":1534732471000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Augmentation of hepatoprotective potential of Aegle marmelos in combination with piperine in carbon tetrachloride model in wistar rats"],"prefix":"10.1186","volume":"12","author":[{"given":"Deepti","family":"Rathee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjoo","family":"Kamboj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shabir","family":"Sidhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,8,20]]},"reference":[{"key":"463_CR1","volume-title":"Clinically useful heabal drugs","author":"SS Agarwal","year":"2005","unstructured":"Agarwal SS, Tamrakar BP, Paridhavi M (2005) Clinically useful heabal drugs, 1st edn. Ahuja publishing house, Delhi","edition":"1"},{"key":"463_CR2","first-page":"499","volume-title":"Indian medicinal plants","author":"KR Kirtikar","year":"1993","unstructured":"Kirtikar KR, Basu BD (1993) Indian medicinal plants. Periodical experts books agency, New Delhi, pp 499\u2013505"},{"key":"463_CR3","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S2221-1691(11)60049-X","volume":"1","author":"S Balakumar","year":"2011","unstructured":"Balakumar S, Rajan S, Thirunalasundari T, Jeeva S (2011) Antifungal activity of Aegle marmelos (L.) Correa (Rutaceae) leaf extract on dermatophytes. Asian Pac J Trop Biomed 1:309\u2013312","journal-title":"Asian Pac J Trop Biomed"},{"key":"463_CR4","doi-asserted-by":"publisher","first-page":"188","DOI":"10.4103\/1319-3767.96452","volume":"18","author":"SK Das","year":"2012","unstructured":"Das SK, Roy C (2012) The protective role of Aegle marmelos on aspirin\u2013induced gastro-duodenal ulceration in albino rat model: a possible involvement of antioxidants. Saudi J Gastroenterol 18:188\u2013194","journal-title":"Saudi J Gastroenterol"},{"key":"463_CR5","doi-asserted-by":"publisher","first-page":"393","DOI":"10.4103\/0253-7613.83108","volume":"43","author":"JM Benni","year":"2011","unstructured":"Benni JM, Jayanthi MK, Suresha RN (2011) Evaluation of the anti-inflammatory activity of Aegle marmelos (Bilwa) root. Indian J Pharmacol 43:393\u2013397","journal-title":"Indian J Pharmacol"},{"key":"463_CR6","first-page":"81","volume":"48","author":"MC Sabu","year":"2004","unstructured":"Sabu MC, Kuttan R (2004) Antidiabetic activity of Aegle marmelos and its relationship with its antioxidant properties. Indian J Physiol Pharmacol 48:81\u201388","journal-title":"Indian J Physiol Pharmacol"},{"key":"463_CR7","first-page":"98","volume":"3","author":"S Singh","year":"2013","unstructured":"Singh S, Singh SK, Srivastava S, Singh P, Trivedi M, Shanker P, Dixit RK, Rana RS (2013) Experimental evaluation of diuretic activity of Aegle marmelos in rats. Int J Pharm Biol Sci 3:98\u2013102","journal-title":"Int J Pharm Biol Sci"},{"key":"463_CR8","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/2008-2231-20-94","volume":"20","author":"SS Agrawal","year":"2012","unstructured":"Agrawal SS, Kumar A, Gullaiya S, Dubey V, Nagar A, Tiwari P, Dhar P, Singh V (2012) Antifertility activity of methanolic bark extract of Aegle marmelos (L.) in male wistar rats. DARU J Pharm Sci 20:94","journal-title":"DARU J Pharm Sci"},{"key":"463_CR9","first-page":"83","volume":"2","author":"V Singanan","year":"2007","unstructured":"Singanan V, Singanan M, Begum H (2007) The hepatoprotective effect of bael leaves (Aegle marmelos) in alcohol induced liver injury in albino rats. Int J Sci Tech 2:83\u201392","journal-title":"Int J Sci Tech"},{"key":"463_CR10","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1177\/1534735412451320","volume":"12","author":"MS Baliga","year":"2013","unstructured":"Baliga MS, Thilakchand KR, Rai MP, Rao S, Venkatesh P (2013) Aegle marmelos (L.) Correa (Bael) and its phytochemicals in the treatment and prevention of cancer. Integr Cancer Ther 12:187\u2013196","journal-title":"Integr Cancer Ther"},{"key":"463_CR11","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/S1995-7645(14)60275-3","volume":"7","author":"F Tasleem","year":"2014","unstructured":"Tasleem F, Azhar I, Ali SN, Perveen S, Mahmood ZA (2014) Analgesic and anti-inflammatory activities of Piper nigrum L. Asian Pac J Trop Med 7:461\u2013468","journal-title":"Asian Pac J Trop Med"},{"key":"463_CR12","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1089\/jmf.2010.1065","volume":"13","author":"MH Mehmood","year":"2010","unstructured":"Mehmood MH, Gilani AH (2010) Pharmacological basis for the medicinal use of black pepper and piperine in gastrointestinal disorders. J Med Food 13:1086\u20131096","journal-title":"J Med Food"},{"key":"463_CR13","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1055\/s-2006-959721","volume":"59","author":"IB Koul","year":"1993","unstructured":"Koul IB, Kapil A (1993) Evaluation of the liver protective potential of piperine, an active principle of black and long peppers. Planta Med 59:413\u2013417","journal-title":"Planta Med"},{"key":"463_CR14","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.tox.2006.09.019","volume":"228","author":"S Avasarala","year":"2006","unstructured":"Avasarala S, Yang L, Sun Y, Leung AWC, Chan WY, Cheung WT, Lee SST (2006) A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in Cyp2e1-null mice. Toxicology 228:310\u2013322","journal-title":"Toxicology"},{"key":"463_CR15","doi-asserted-by":"publisher","first-page":"608","DOI":"10.3181\/00379727-104-25923","volume":"104","author":"RO Recknagel","year":"1960","unstructured":"Recknagel RO, Lombardi B, Schotz MC (1960) A new insight into pathogenesis of carbon tetrachloride fat infiltration. Proc Soc Exp Biol Med 104:608\u2013610","journal-title":"Proc Soc Exp Biol Med"},{"key":"463_CR16","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/0003-9861(84)90205-4","volume":"235","author":"J Terao","year":"1984","unstructured":"Terao J, Asano I, Matsushita S (1984) High-performance liquid chromatographic determination of phospholipid peroxidation products of rat liver after carbon tetrachloride administration. Arch Biochem Biophys 235:326\u2013333","journal-title":"Arch Biochem Biophys"},{"key":"463_CR17","first-page":"6","volume-title":"Phytochemicals methods","author":"JB Harbrone","year":"1973","unstructured":"Harbrone JB (1973) Phytochemicals methods. Chapman and Hall Ltd, London, p 6"},{"key":"463_CR18","first-page":"15","volume-title":"Practical pharmacognosy","author":"CK Kokate","year":"1986","unstructured":"Kokate CK (1986) Practical pharmacognosy, 1st edn. Vallabh Prakashan, New Delhi, pp 15\u201330","edition":"1"},{"key":"463_CR19","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.jpba.2005.04.052","volume":"41","author":"Y Zu","year":"2006","unstructured":"Zu Y, Li C, Fu Y, Zhao C (2006) Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. J Pharm Biomed Anal 41:714\u2013719","journal-title":"J Pharm Biomed Anal"},{"key":"463_CR20","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1590\/S0102-695X2012005000111","volume":"23","author":"LP Landim","year":"2013","unstructured":"Landim LP, Feitoza GS, Costa JGM (2013) Development and validation of a HPLC method for the quantification of three flavonoids in a crude extract of Dimorphandra gardneriana. Rev bras farmacogn 23:58\u201364","journal-title":"Rev bras farmacogn"},{"key":"463_CR21","first-page":"211","volume":"26","author":"P Molyneux","year":"2004","unstructured":"Molyneux P (2004) The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin J. Sci. Technol 26:211\u2013219","journal-title":"Songklanakarin J. Sci. Technol"},{"key":"463_CR22","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3109\/10715769709097799","volume":"26","author":"NJ Miller","year":"1997","unstructured":"Miller NJ, Rice-Evans CA (1997) Factors influencing the antioxidant activity determined by the ABTS\u00b7\u2009+\u2009radical cation assay. Free Radic Res 26:195\u2013199","journal-title":"Free Radic Res"},{"key":"463_CR23","doi-asserted-by":"publisher","first-page":"4976","DOI":"10.1021\/jf020136b","volume":"50","author":"MI Gil","year":"2002","unstructured":"Gil MI, Tom\u00e1s-Barber\u00e1n FA, Hess-Pierce B, Kader AA (2002) Antioxidant capacities, phenolic compounds, carotenoids, and vitamin C contents of nectarine, peach, and plum cultivars from California. J Agric Food Chem 50:4976\u20134982","journal-title":"J Agric Food Chem"},{"key":"463_CR24","doi-asserted-by":"crossref","first-page":"118","DOI":"10.31254\/phyto.2014.3207","volume":"3","author":"OB Adewale","year":"2014","unstructured":"Adewale OB, Adekeye AO, Akintayo CO, Onikanni A, Sabiu S (2014) Carbon tetrachloride (CCl4)-induced hepatic damage in experimental Sprague Dawley rats: antioxidant potential of Xylopia aethiopica. J Phytopharmacol 3:118\u2013123","journal-title":"J Phytopharmacol"},{"key":"463_CR25","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.phymed.2006.05.004","volume":"14","author":"A Veerappan","year":"2007","unstructured":"Veerappan A, Miyazaki S, Kadarkaraisamy M, Ranganathan D (2007) Acute and subacute toxicity studies of Aegle marmelos Corr., an Indian medicinal plant. Phytomed 14:209\u2013215","journal-title":"Phytomed"},{"key":"463_CR26","first-page":"2014","volume":"2014","author":"M Rasool","year":"2014","unstructured":"Rasool M, Iqbal J, Malik A, Ramzan HS, Qureshi MS, Asif M, Qazi MH, Kamal MA, Chaudhary AG, Al-Qahtani MH, Gan SH (2014) Hepatoprotective effects of Silybum marianum (Silymarin) and Glycyrrhiza glabra (Glycyrrhizin) in combination: a possible synergy. Evid Based Comp Altern Med 2014:2014","journal-title":"Evid Based Comp Altern Med"},{"key":"463_CR27","first-page":"277","volume":"40","author":"AR Hiwale","year":"2002","unstructured":"Hiwale AR, Dhuley JN, Naik SR (2002) Effect of co-administration of piperine on pharmacokinetics of \u03b2-lactam antibiotics in rats. Indian J Exp Biol 40:277\u2013281","journal-title":"Indian J Exp Biol"},{"key":"463_CR28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265\u2013275","journal-title":"J Biol Chem"},{"key":"463_CR29","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351\u2013358","journal-title":"Anal Biochem"},{"key":"463_CR30","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","volume":"82","author":"GL Ellman","year":"1959","unstructured":"Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82:70\u201377","journal-title":"Arch Biochem Biophys"},{"key":"463_CR31","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/0006-2952(88)90169-4","volume":"37","author":"J Robak","year":"1988","unstructured":"Robak J, Gryglewski RJ (1988) Flavonoids are scavengers of superoxide anions. Biochem Pharmacol 37:837\u2013841","journal-title":"Biochem Pharmacol"},{"key":"463_CR32","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/B978-0-12-091302-2.50032-3","volume-title":"Methods of enzymatic analysis","author":"H Aebi","year":"1974","unstructured":"Aebi H (1974) Catalase. In: Bergmeyer HU (ed) Methods of enzymatic analysis. Academic Press, New York, pp 673\u2013677"},{"key":"463_CR33","doi-asserted-by":"crossref","first-page":"5475","DOI":"10.1016\/S0021-9258(19)41206-4","volume":"25","author":"IN Carlberg","year":"1975","unstructured":"Carlberg IN, Mannervik BE (1975) Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J Biol Chem 25:5475\u20135480","journal-title":"J Biol Chem"},{"key":"463_CR34","doi-asserted-by":"crossref","first-page":"7130","DOI":"10.1016\/S0021-9258(19)42083-8","volume":"249","author":"WH Habig","year":"1974","unstructured":"Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione S-transferases the first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130\u20137139","journal-title":"J Biol Chem"},{"key":"463_CR35","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1093\/carcin\/19.6.1133","volume":"19","author":"MO Athar","year":"1998","unstructured":"Athar MO, Iqbal MO (1998) Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress. Carcinogenesis 19:1133\u20131139","journal-title":"Carcinogenesis"},{"key":"463_CR36","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/0003-9861(65)90412-1","volume":"109","author":"N Zaheer","year":"1965","unstructured":"Zaheer N, Tewari KK, Krishnan PS (1965) Exposure and solubilization of hepatic mitochondrial shunt dehydrogenases. Arch Biochem Biophys 109:646\u2013648","journal-title":"Arch Biochem Biophys"},{"key":"463_CR37","first-page":"1","volume":"4","author":"NA Siddique","year":"2010","unstructured":"Siddique NA, Mujeeb M, Najmi AK, Akram M (2010) Evaluation of antioxidant activity, quantitative estimation of phenols and flavonoids in different parts of Aegle marmelos. Afr J Plant Sci 4:1\u20135","journal-title":"Afr J Plant Sci"},{"issue":"Suppl 1","key":"463_CR38","first-page":"S67","volume":"9","author":"CJ Nair","year":"2017","unstructured":"Nair CJ, Ahamad S, Khan W, Anjum V, Mathur R (2017) Development and validation of high-performance thin-layer chromatography method for simultaneous determination of polyphenolic compounds in medicinal plants. Pharmacognosy Res 9(Suppl 1):S67","journal-title":"Pharmacognosy Res"},{"key":"463_CR39","first-page":"1360","volume":"3","author":"K Jayachandra","year":"2011","unstructured":"Jayachandra K, Sivaraman T (2011) Hepatoprotective effect of Aegle Marmelos (L.) Corr. Leaf powder (Crude) against carbon tetrachloride-induced hepatic damage in albino rats. J Pharma Sci Res 3:1360\u20131363","journal-title":"J Pharma Sci Res"},{"key":"463_CR40","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/j.fct.2009.12.011","volume":"48","author":"E Shaker","year":"2010","unstructured":"Shaker E, Mahmoud H, Silymarin Mnaa S (2010) Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage. Food Chem Toxicol 48:803\u2013806","journal-title":"Food Chem Toxicol"},{"key":"463_CR41","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1155\/2011\/142739","volume":"2011","author":"ZA Zakaria","year":"2011","unstructured":"Zakaria ZA, Rofiee MS, Somchit MN, Zuraini A, Sulaiman MR, Teh LK, Salleh MZ, Long K (2011) Hepatoprotective activity of dried-and fermented-processed virgin coconut oil. Evid Based Complement Altern Med 2011:2011","journal-title":"Evid Based Complement Altern Med"},{"key":"463_CR42","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1006\/bbrc.2002.6541","volume":"291","author":"E Hazai","year":"2002","unstructured":"Hazai E, Vereczkey L, Monostory K (2002) Reduction of toxic metabolite formation of acetaminophen. Biochem Biophys Res Commun 291:1089\u20131094","journal-title":"Biochem Biophys Res Commun"},{"key":"463_CR43","first-page":"57","volume":"21","author":"B Rajkapoor","year":"2008","unstructured":"Rajkapoor B, Venugopal Y, Anbu J, Harikrishnan N, Gobinath M, Ravichandran V (2008) Protective effect of Phyllanthus polyphyllus on acetaminophen induced hepatotoxicity in rats. Pak J Pharm Sci 21:57\u201362","journal-title":"Pak J Pharm Sci"},{"key":"463_CR44","first-page":"431","volume":"5","author":"AK Gupta","year":"2006","unstructured":"Gupta AK, Chitme H, Dass SK, Misra N (2006) Hepatoprotective activity of Rauwolfia serpentina rhizome in paracetamol intoxicated rats. J Pharmacol Toxicol 5:431\u2013437","journal-title":"J Pharmacol Toxicol"},{"key":"463_CR45","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s13197-010-0221-z","volume":"50","author":"VP Reddy","year":"2013","unstructured":"Reddy VP, Urooj A (2013) Antioxidant properties and stability of Aegle marmelos leaves extracts. J Food Sci Tech 50:135\u2013140","journal-title":"J Food Sci Tech"},{"key":"463_CR46","doi-asserted-by":"publisher","first-page":"4290","DOI":"10.1021\/jf0502698","volume":"53","author":"RL Prior","year":"2005","unstructured":"Prior RL, Wu X, Schaich K (2005) Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements. J Agric Food Chem 53:4290\u20134302","journal-title":"J Agric Food Chem"},{"key":"463_CR47","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/S0192-0561(00)00073-4","volume":"22","author":"MI Luster","year":"2000","unstructured":"Luster MI, Simeonova PP, Gallucci RM, Matheson JM, Yucesoy B (2000) Immunotoxicology: role of inflammation in chemical-induced hepatotoxicity. Int J Immunopharmacol 22:1143\u20131147","journal-title":"Int J Immunopharmacol"},{"key":"463_CR48","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1038\/aps.2012.62","volume":"33","author":"R Domitrovi\u0107","year":"2012","unstructured":"Domitrovi\u0107 R, Jakovac H, Marchesi VV, Vladimir-Kne\u017eevi\u0107 S, Cvijanovi\u0107 O, Tadi\u0107 \u017d, Romi\u0107 \u017d, Raheli\u0107 D (2012) Differential hepatoprotective mechanisms of rutin and quercetin in CCl4-intoxicated BALB\/cN mice. Acta Pharmacol Sin 33:1260\u20131270","journal-title":"Acta Pharmacol Sin"},{"key":"463_CR49","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s40659-015-0022-y","volume":"48","author":"MM Hafez","year":"2015","unstructured":"Hafez MM, Al-Harbi NO, Al-Hoshani AR, Al-Hosaini KA, Al Shrari SD, Al Rejaie SS, Sayed-Ahmed MM, Al-Shabanah OA (2015) Hepato-protective effect of rutin via IL-6\/STAT3 pathway in CCl 4-induced hepatotoxicity in rats. Biol Res 48:30","journal-title":"Biol Res"},{"key":"463_CR50","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1503\/cmaj.1040752","volume":"172","author":"EG Giannini","year":"2005","unstructured":"Giannini EG, Testa R, Savarino V (2005) Liver enzyme alteration: a guide for clinicians. Can Med Assoc J 172:367\u2013379","journal-title":"Can Med Assoc J"},{"key":"463_CR51","doi-asserted-by":"publisher","first-page":"4478","DOI":"10.3390\/molecules15064478","volume":"15","author":"S Sasidharan","year":"2010","unstructured":"Sasidharan S, Aravindran S, Latha LY, Vijenthi R, Saravanan D, Amutha S (2010) In vitro antioxidant activity and hepatoprotective effects of Lentinula edodes against paracetamol-induced hepatotoxicity. Molecules 15:4478\u20134489","journal-title":"Molecules"},{"key":"463_CR52","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.fshw.2015.02.002","volume":"4","author":"A Abirami","year":"2015","unstructured":"Abirami A, Nagarani G, Siddhuraju P (2015) Hepatoprotective effect of leaf extracts from Citrus hystrix and C. maxima against paracetamol induced liver injury in rats. Food Sci Human Well 4:35\u201341","journal-title":"Food Sci Human Well"},{"key":"463_CR53","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0378-8741(98)00088-9","volume":"63","author":"SK Mitra","year":"1998","unstructured":"Mitra SK, Venkataranganna MV, Sundaram R, Gopumadhavan S (1998) Protective effect of HD-03, a herbal formulation, against various hepatotoxic agents in rats. J Ethnopharmacol 63:181\u2013186","journal-title":"J Ethnopharmacol"},{"key":"463_CR54","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.1155\/2012\/436139","volume":"2012","author":"A Mondal","year":"2012","unstructured":"Mondal A, Karan SK, Singha T, Rajalingam D, Maity TK (2012) Evaluation of hepatoprotective effect of leaves of Cassia sophera Linn\u201d. Evid Based Complement Altern Med 2012:2012","journal-title":"Evid Based Complement Altern Med"},{"key":"463_CR55","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1007\/BF02976680","volume":"26","author":"S Lee","year":"2003","unstructured":"Lee S, Lee YS, Jung SH, Kang SS, Shin KH (2003) Anti-oxidant activities of fucosterol from the marine algae Pelvetia siliquosa. Arch Pharm Res 26:719\u2013722","journal-title":"Arch Pharm Res"},{"key":"463_CR56","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/S0378-8741(03)00148-X","volume":"87","author":"N Kamalakkannan","year":"2003","unstructured":"Kamalakkannan N, Prince PSM (2003) Hypoglycaemic effect of water extracts of Aegle marmelos fruits in streptozotocin diabetic rats. Ethnopharmacol 87:207\u2013210","journal-title":"Ethnopharmacol"},{"key":"463_CR57","first-page":"1285","volume":"41","author":"N Kamalakkannan","year":"2003","unstructured":"Kamalakkannan N, Stanely MPP (2003) Effect of Aegle marmelos Correa. (Bael) fruit extract on tissue antioxidants in streptozotocin diabetic rats. Indian J Exp Biol 41:1285\u20131288","journal-title":"Indian J Exp Biol"},{"key":"463_CR58","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.phymed.2016.02.026","volume":"23","author":"Y Xin","year":"2016","unstructured":"Xin Y, Wei J, Chunhua M, Danhong Y, Jianguo Z, Zongqi C, Jian-an B (2016) Protective effects of ginsenoside Rg1 against carbon tetrachloride-induced liver injury in mice through suppression of inflammation. Phytomed 23:583\u2013588","journal-title":"Phytomed"},{"key":"463_CR59","doi-asserted-by":"publisher","first-page":"846","DOI":"10.12816\/0001647","volume":"53","author":"WM Elzefzafy","year":"2013","unstructured":"Elzefzafy WM, AboulEla A, Maabady MH, Shahin RS (2013) Role of tumor necrosis factor alpha, Ghrelin, evoked potentials in hepatic encephalopathy. Egypt J Hosp Med 53:846\u2013854","journal-title":"Egypt J Hosp Med"},{"key":"463_CR60","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.3748\/wjg.v12.i11.1681","volume":"12","author":"LJ Zhang","year":"2006","unstructured":"Zhang LJ, Wang XZ (2006) Interleukin-10 and chronic liver disease. World J Gastroenterol 12:1681","journal-title":"World J Gastroenterol"},{"key":"463_CR61","doi-asserted-by":"publisher","first-page":"4444","DOI":"10.1021\/jf8002174","volume":"56","author":"H Shimoda","year":"2008","unstructured":"Shimoda H, Tanaka J, Kikuchi M, Fukuda T, Ito H, Hatano T, Yoshida T (2008) Walnut polyphenols prevent liver damage induced by carbon tetrachloride and D-galactosamine: hepatoprotective hydrolyzable tannins in the kernel pellicles of walnut. J Agric Food Chem 56:4444\u20134449","journal-title":"J Agric Food Chem"},{"key":"463_CR62","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.jep.2011.03.061","volume":"136","author":"L Bhoopat","year":"2011","unstructured":"Bhoopat L, Srichairatanakool S, Kanjanapothi D, Taesotikul T, Thananchai H, Bhoopat T (2011) Hepatoprotective effects of lychee (Litchi chinensis Sonn.): a combination of antioxidant and antiapoptotic activities. J Ethnopharmacol 136:55\u201366","journal-title":"J Ethnopharmacol"}],"container-title":["Chemistry Central Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13065-018-0463-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13065-018-0463-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13065-018-0463-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T19:51:00Z","timestamp":1661802660000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcchem.biomedcentral.com\/articles\/10.1186\/s13065-018-0463-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,20]]},"references-count":62,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["463"],"URL":"https:\/\/doi.org\/10.1186\/s13065-018-0463-9","relation":{},"ISSN":["1752-153X"],"issn-type":[{"value":"1752-153X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,20]]},"assertion":[{"value":"26 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"94"}}