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The antibacterial capability of GO-SB was improved when it was grafted with ethyl cellulose (EC) and polyvinyl alcohol (PVA) to form GO-SB\/EC\/PVA hydrogels. Characterization of GO-SB nanosheets and GO-SB\/EC\/PVA hydrogels was accomplished by using FTIR, SEM, XRD, and thermal studies. The antimicrobial activity was carried out against Gram positive bacteria [<jats:italic>Micrococcus leutus<\/jats:italic> &amp; <jats:italic>Staphylococcus aureus<\/jats:italic>], Gram negative bacteria [<jats:italic>Escherichia coli<\/jats:italic>, <jats:italic>Pseudomonas aeruginosa<\/jats:italic>] and pathogenic fungal yeast [<jats:italic>Candida albicans<\/jats:italic>] applying the disc diffusion method. The disc diffusion method results showed that the improved GO-SB\/EC\/PVA exhibited a reasonable level of antimicrobial capability against <jats:italic>Micrococcus leutus<\/jats:italic>, demonstrating that the antimicrobial improvement of GO-SB was more effective in the GO-SB\/EC\/PVA hydrogels by increasing the inhibition zone of Gram-positive bacteria, <jats:italic>Micrococcus leutus<\/jats:italic> from (13.0 to 16.0\u00a0mm).<\/jats:p>\n                <jats:p><jats:bold>Graphical abstract<\/jats:bold><\/jats:p>","DOI":"10.1186\/s13065-024-01221-3","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T18:02:41Z","timestamp":1719424961000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Fluffy-like amphiphilic graphene oxide and its effects on improving the antibacterial activity and thermal outstanding of ethyl cellulose \/polyvinyl alcohol hydrogel film"],"prefix":"10.1186","volume":"18","author":[{"given":"Hebat-Allah S.","family":"Tohamy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossam M.","family":"El-Masry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"1221_CR1","unstructured":"Roy N, Saha N, Saha P. 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