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Stability studies were carried out for both drugs using different five degradation conditions. The chromatographic separation was achieved using BDS Thermo-Hypersil C8 (150\u00a0mm x 4.6\u00a0mm, 5\u00a0\u03bcm) column and hybrid micellar mobile phase composed of 50 gm of sodium lauryl sulphate in 500 mL purified water with 100mL of 2-Propanol and 3 mL triethylamine and then completed with purified water to 1000mL, and the mobile phase pH was 3.3. The (PDA) detector was used at 223\u00a0nm, 40\u00a0\u00b0C column temperature, 1mL\/min flow rate and 20\u00b5L injection volume. The retention times of DAP and MET were (5.37\u2009\u00b1\u20090.4\u00a0min) and (7.64\u2009\u00b1\u20090.2\u00a0min), respectively. Linearity was constructed in ranges of (0.2\u20137\u00a0\u00b5g\/mL) for DAP and (50\u2013700\u00a0\u00b5g\/mL) for MET. Mean percentage recoveries of DAP and MET were 99.88%\u00b10.53 and 100.034%\u00b10.60, respectively indicates good accuracy. The developed approach was validated according to ICH guidelines and efficiently applied for the analysis of DAP and MET in Dexigloflozin plus\n                    <jats:sup>\u00ae<\/jats:sup>\n                    5\/500 tablets. For the greenness assessment the analytical eco-scale, Complex MoGAPI and AGREE methods were applied.\n                  <\/jats:p>","DOI":"10.1186\/s13065-025-01537-8","type":"journal-article","created":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T04:51:57Z","timestamp":1750481517000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Stability indicating green micellar liquid chromatographic method for simultaneous analysis of Metformin and dapagliflozin in their tablets"],"prefix":"10.1186","volume":"19","author":[{"given":"Aya A.","family":"Marie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed G.","family":"Yassin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Roshdy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,21]]},"reference":[{"key":"1537_CR1","doi-asserted-by":"crossref","unstructured":"Hegazi R, El-Gamal M, Abdel-Hady N, Hamdy OJA. 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