{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:40:24Z","timestamp":1787020824676,"version":"build-2736575974"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,7,28]],"date-time":"2015-07-28T00:00:00Z","timestamp":1438041600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Czech Science Foundation","doi-asserted-by":"crossref","award":["13-29577S"],"award-info":[{"award-number":["13-29577S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Grant Agency of the Charles University in Prague","award":["220214"],"award-info":[{"award-number":["220214"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Parasites Vectors"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1186\/s13071-015-1007-y","type":"journal-article","created":{"date-parts":[[2015,7,27]],"date-time":"2015-07-27T09:03:06Z","timestamp":1437987786000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Antibody response of definitive hosts against antigens of two life stages of the neuropathogenic schistosome Trichobilharzia regenti"],"prefix":"10.1186","volume":"8","author":[{"given":"Libu\u0161e","family":"Turjanicov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libor","family":"Mike\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Peckov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Hor\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,7,28]]},"reference":[{"key":"1007_CR1","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1079\/JOH2002113","volume":"76","author":"K Hr\u00e1dkov\u00e1","year":"2002","unstructured":"Hr\u00e1dkov\u00e1 K, Hor\u00e1k P. Neurotropic behaviour of Trichobilharzia regenti in ducks and mice. J Helminthol. 2002;76:137\u201341.","journal-title":"J Helminthol"},{"key":"1007_CR2","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1017\/S0031182099005132","volume":"119","author":"P Hor\u00e1k","year":"1999","unstructured":"Hor\u00e1k P, Dvo\u0159\u00e1k J, Kol\u00e1\u0159ov\u00e1 L, Trefil L. Trichobilharzia regenti, a pathogen of the avian and mammalian central nervous systems. Parasitology. 1999;119:577\u201381.","journal-title":"Parasitology"},{"key":"1007_CR3","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1051\/parasite\/2008153299","volume":"15","author":"P Hor\u00e1k","year":"2008","unstructured":"Hor\u00e1k P, Mike\u0161 L, Rudolfov\u00e1 J, Kol\u00e1\u0159ov\u00e1 L. Penetration of Trichobilharzia cercariae into mammals: dangerous or negligible event? Parasite. 2008;15:299\u2013303.","journal-title":"Parasite"},{"key":"1007_CR4","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.exppara.2011.04.006","volume":"128","author":"L Lichtenbergov\u00e1","year":"2011","unstructured":"Lichtenbergov\u00e1 L, Lassmann H, Jones MK, Kol\u00e1\u0159ov\u00e1 L, Hor\u00e1k P. Trichobilharzia regenti: Host immune response in the pathogenesis of neuroinfection in mice. Exp Parasitol. 2011;128:328\u201335.","journal-title":"Exp Parasitol"},{"key":"1007_CR5","doi-asserted-by":"publisher","first-page":"3766","DOI":"10.4049\/jimmunol.172.6.3766","volume":"172","author":"P Kou\u0159ilov\u00e1","year":"2004","unstructured":"Kou\u0159ilov\u00e1 P, Hogg KG, Kol\u00e1\u0159ov\u00e1 L, Mountford AP. Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions. J Immunol. 2004;172:3766\u201374.","journal-title":"J Immunol"},{"key":"1007_CR6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/S0065-308X(02)52012-1","volume":"52","author":"P Hor\u00e1k","year":"2002","unstructured":"Hor\u00e1k P, Kol\u00e1\u0159ov\u00e1 L, Adema CM. Biology of the schistosome genus Trichobilharzia. Adv Parasitol. 2002;52:155\u2013233.","journal-title":"Adv Parasitol"},{"key":"1007_CR7","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s12016-012-8334-y","volume":"45","author":"L Kol\u00e1\u0159ov\u00e1","year":"2013","unstructured":"Kol\u00e1\u0159ov\u00e1 L, Hor\u00e1k P, Sk\u00edrnisson K, Mare\u010dkov\u00e1 H, Doenhoff M. Cercarial dermatitis, a neglected allergic disease. Clin Rev Allergy Immunol. 2013;45:63\u201374.","journal-title":"Clin Rev Allergy Immunol"},{"key":"1007_CR8","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1128\/CMR.00043-14","volume":"28","author":"P Hor\u00e1k","year":"2015","unstructured":"Hor\u00e1k P, Mike\u0161 L, Lichtenbergov\u00e1 L, Sk\u00e1la V, Sold\u00e1nov\u00e1 M, Brant SV. Avian Schistsomes and Outbreaks of Cercarial Dermatitis. Clin Microbiol Rev. 2015;28:165\u201390.","journal-title":"Clin Microbiol Rev"},{"key":"1007_CR9","first-page":"83","volume":"7","author":"M Chanov\u00e1","year":"2012","unstructured":"Chanov\u00e1 M, Lichtenbergov\u00e1 L, Bulantov\u00e1 J, Mike\u0161 L, Hor\u00e1k P. Trichobilharzia regenti: antigenic structures of intravertebrate stages. Cent Eur J Biol. 2012;7:83\u201390.","journal-title":"Cent Eur J Biol"},{"key":"1007_CR10","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s00436-002-0607-6","volume":"88","author":"P Kou\u0159ilov\u00e1","year":"2002","unstructured":"Kou\u0159ilov\u00e1 P, Kol\u00e1\u0159ov\u00e1 L. Variations in immunofluorescent antibody response against Trichobilharzia and Schistosoma antigens in compatible and incompatible hosts. Parasitol Res. 2002;88:513\u201321.","journal-title":"Parasitol Res"},{"key":"1007_CR11","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1365-3024.2008.01059.x","volume":"30","author":"L Lichtenbergov\u00e1","year":"2008","unstructured":"Lichtenbergov\u00e1 L, Kolbekov\u00e1 P, Kou\u0159ilov\u00e1 P, Ka\u0161n\u00fd M, Mike\u0161 L, Haas H, et al. Antibody responses induced by Trichobilharzia regenti antigens in murine and human hosts exhibiting cercarial dermatitis. Parasite Immunol. 2008;30:585\u201395.","journal-title":"Parasite Immunol"},{"key":"1007_CR12","first-page":"21","volume-title":"Abstact Book \u2013 3rd Workshop on Bird Schistosomes and Cercarial Dermatitis","author":"M Ka\u0161n\u00fd","year":"2009","unstructured":"Ka\u0161n\u00fd M, Lichtenbergov\u00e1 L, Kol\u00e1\u0159ov\u00e1 L, Hor\u00e1k P. Identification and characterization of dominant antigens of the bird schistosome Trichobilharzia regenti. In: Mike\u0161 L, Hor\u00e1k P, editors. Abstact Book \u2013 3rd Workshop on Bird Schistosomes and Cercarial Dermatitis. Czech Republic: Charles University in Prague, Faculty of Science; 2009. p. 21."},{"key":"1007_CR13","doi-asserted-by":"crossref","unstructured":"Tizard I. The avian antibody response. Semin Avian Exot Pet Med. 2002;11:2-14.","DOI":"10.1053\/saep.2002.28216"},{"key":"1007_CR14","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1146\/annurev.iy.09.040191.001251","volume":"9","author":"WT McCormack","year":"1991","unstructured":"McCormack WT, Tjoelker LW, Thompson CB. Avian B-cell development: generation of an immunoglobulin repertoire by gene conversion. Annu Rev Immunol. 1991;9:219\u201341.","journal-title":"Annu Rev Immunol"},{"key":"1007_CR15","unstructured":"Higgins DA. Physical and chemical properties of fowl immunoglobulins. Vet Bull. 1975;45:139-154."},{"key":"1007_CR16","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/0167-5699(95)80008-5","volume":"16","author":"GW Warr","year":"1995","unstructured":"Warr GW, Magor KE, Higgins DA. IgY: clues to the origins of modern antibodies. Immunol Today. 1995;16:392\u20138.","journal-title":"Immunol Today"},{"key":"1007_CR17","doi-asserted-by":"crossref","unstructured":"Bengt\u00e9n E, Wilson M, Miller N, Clem LW, Pilstr\u00f6m L, Warr GW. Immunoglobulin isotypes: structure, function, and genetics. Curr Top Microbiol Immunol. 2000;248:189-219.","DOI":"10.1007\/978-3-642-59674-2_9"},{"key":"1007_CR18","doi-asserted-by":"crossref","first-page":"5549","DOI":"10.4049\/jimmunol.153.12.5549","volume":"153","author":"KE Magor","year":"1994","unstructured":"Magor KE, Higgins DA, Middleton DL, Warr GW. One gene encodes the heavy chains for three different forms of IgY in the duck. J Immunol. 1994;153:5549\u201355.","journal-title":"J Immunol"},{"key":"1007_CR19","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1017\/S0022149X09990721","volume":"84","author":"L Kol\u00e1\u0159ov\u00e1","year":"2010","unstructured":"Kol\u00e1\u0159ov\u00e1 L, Hor\u00e1k P, Sk\u00edrnisson K. Methodical approaches in the identification of areas with a potential risk of infection by bird schistosomes causing cercarial dermatitis. J Helminthol. 2010;84:327\u201335.","journal-title":"J Helminthol"},{"key":"1007_CR20","first-page":"323","volume":"58","author":"PL Ng","year":"1986","unstructured":"Ng PL, Higgins DA. Bile immunoglobulin of the duck (Anas platyrhynchos). I. Preliminary characterization and ontogeny. Immunology. 1986;58:323\u20137.","journal-title":"Immunology"},{"key":"1007_CR21","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/0305-0491(90)90100-8","volume":"97","author":"SS Liu","year":"1990","unstructured":"Liu SS, Higgins DA. Yolk-sac transmission and post-hatching ontogeny of serum immunoglobulins in the duck (Anas platyrhynchos). Comp Biochem Physiol Part B Comp Biochem. 1990;97:637\u201344.","journal-title":"Comp Biochem Physiol Part B Comp Biochem"},{"key":"1007_CR22","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1051\/parasite\/1998054349","volume":"5","author":"P Hor\u00e1k","year":"1998","unstructured":"Hor\u00e1k P, Kol\u00e1\u0159ov\u00e1 L, Dvo\u0159\u00e1k J. Trichobilharzia regenti n. sp. (Schistosomatidae, Bilharziellinae), a new nasal schistosome from Europe. Parasite. 1998;5:349\u201357.","journal-title":"Parasite"},{"key":"1007_CR23","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1163\/002829684X00236","volume":"34","author":"EA Meuleman","year":"1984","unstructured":"Meuleman EA, Huyer AR, Mooij JH. Maintenance of the life cycle of Trichobilharzia ocellata via the duck Anas platyrhynchos and the pond snail Lymnaea stagnalis. Neth J Zool. 1984;34:414\u20137.","journal-title":"Neth J Zool"},{"key":"1007_CR24","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0022-1759(98)00170-7","volume":"221","author":"A Frey","year":"1998","unstructured":"Frey A, Di Canzio J, Zurakowski D. A statistically defined endpoint titer determination method for immunoassays. J Immunol Methods. 1998;221:35\u201341.","journal-title":"J Immunol Methods"},{"key":"1007_CR25","first-page":"58","volume":"46","author":"BD Guth","year":"1979","unstructured":"Guth BD, Blankespoor HD, Reimink RL, Johnson WC. Prevalence of dermatitis-producing schistosomes in natural bird populations of lower Michigan. Proc Helminthol Soc Wash. 1979;46:58\u201363.","journal-title":"Proc Helminthol Soc Wash"},{"key":"1007_CR26","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1007\/s004360100431","volume":"87","author":"L Kol\u00e1\u0159ov\u00e1","year":"2001","unstructured":"Kol\u00e1\u0159ov\u00e1 L, Hor\u00e1k P, \u010cada F. Histopathology of CNS and nasal infections caused by Trichobilharzia regenti in vertebrates. Parasitol Res. 2001;87:644\u201350.","journal-title":"Parasitol Res"},{"key":"1007_CR27","first-page":"499","volume":"62","author":"DA Higgins","year":"1987","unstructured":"Higgins DA, Shortridge KF, Ng PL. Bile immunoglobulin of the duck (Anas platyrhychos) II. Antibody response in influenza A virus infections. Immunology. 1987;62:499.","journal-title":"Immunology"},{"key":"1007_CR28","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.dci.2012.10.006","volume":"39","author":"GR Banat","year":"2013","unstructured":"Banat GR, Tkalcic S, Dzielawa JA, Jackwood MW, Saggese MD, Yates L, et al. Association of the chicken MHC B haplotypes with resistance to avian coronavirus. Dev Comp Immunol. 2013;39:430\u20137.","journal-title":"Dev Comp Immunol"},{"key":"1007_CR29","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.ijpara.2008.06.010","volume":"39","author":"K Dole\u010dkov\u00e1","year":"2009","unstructured":"Dole\u010dkov\u00e1 K, Ka\u0161n\u00fd M, Mike\u0161 L, Cartwright J, Jedelsk\u00fd P, Schneider EL, et al. The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti. Int J Parasitol. 2009;39:201\u201311.","journal-title":"Int J Parasitol"},{"key":"1007_CR30","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1186\/1756-3305-4-162","volume":"4","author":"A Ligasov\u00e1","year":"2011","unstructured":"Ligasov\u00e1 A, Bulantov\u00e1 J, \u0160ebesta O, Ka\u0161n\u00fd M, Koberna K, Mike\u0161 L. Secretory glands in cercaria of the neuropathogenic schistosome Trichobilharzia regenti - ultrastructural characterization, 3-D modelling, volume and pH estimations. Parasit Vectors. 2011;4:162.","journal-title":"Parasit Vectors"}],"container-title":["Parasites & Vectors"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13071-015-1007-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13071-015-1007-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13071-015-1007-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13071-015-1007-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T02:21:55Z","timestamp":1717986115000},"score":1,"resource":{"primary":{"URL":"https:\/\/parasitesandvectors.biomedcentral.com\/articles\/10.1186\/s13071-015-1007-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,28]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["1007"],"URL":"https:\/\/doi.org\/10.1186\/s13071-015-1007-y","relation":{},"ISSN":["1756-3305"],"issn-type":[{"value":"1756-3305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,28]]},"assertion":[{"value":"5 March 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"400"}}