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To date, only a limited number of studies concerning the molecular biology of\n                      <jats:italic>F. magna<\/jats:italic>\n                      exist. Therefore, the objective of the present study was to determine the complete mitochondrial (mt) genome sequence of\n                      <jats:italic>F. magna<\/jats:italic>\n                      , and assess the phylogenetic relationships of this fluke with other trematodes based on the mtDNA dataset.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      The complete\n                      <jats:italic>F. magna<\/jats:italic>\n                      mt genome sequence is 14,047\u00a0bp. The gene content and arrangement of the\n                      <jats:italic>F. magna<\/jats:italic>\n                      mt genome is similar to those of\n                      <jats:italic>Fasciola<\/jats:italic>\n                      spp\n                      <jats:italic>.<\/jats:italic>\n                      , except that\n                      <jats:italic>trn<\/jats:italic>\n                      E is located between\n                      <jats:italic>trn<\/jats:italic>\n                      G and the only non-coding region in\n                      <jats:italic>F. magna<\/jats:italic>\n                      mt genome. Phylogenetic relationships of\n                      <jats:italic>F. magna<\/jats:italic>\n                      with selected trematodes using Bayesian inference (BI) was reconstructed based on the concatenated amino acid sequences for 12 protein-coding genes, which confirmed that the genus\n                      <jats:italic>Fascioloides<\/jats:italic>\n                      is closely related to the genus\n                      <jats:italic>Fasciola<\/jats:italic>\n                      ; the intergeneric differences of amino acid composition between the genera\n                      <jats:italic>Fascioloides<\/jats:italic>\n                      and\n                      <jats:italic>Fasciola<\/jats:italic>\n                      ranged 17.97\u201318.24\u00a0%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The determination of\n                      <jats:italic>F. magna<\/jats:italic>\n                      mt genome sequence provides a valuable resource for further investigations of the phylogeny of the family Fasciolidae and other trematodes, and represents a useful platform for designing appropriate molecular markers.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13071-016-1699-7","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T08:12:17Z","timestamp":1470298337000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Complete mitochondrial genome of the giant liver fluke Fascioloides magna (Digenea: Fasciolidae) and its comparison with selected trematodes"],"prefix":"10.1186","volume":"9","author":[{"given":"Jun","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Jun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Hua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Leontovy\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Ka\u0161n\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing-Quan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,8,4]]},"reference":[{"key":"1699_CR1","first-page":"497","volume":"4","author":"R Bassi","year":"1875","unstructured":"Bassi R. 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