{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:40:20Z","timestamp":1787020820298,"version":"build-2736575974"},"reference-count":95,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T00:00:00Z","timestamp":1553558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Federal State of Hesse LOEWE","award":["LOEWE DRUID project #C2"],"award-info":[{"award-number":["LOEWE DRUID project #C2"]}]},{"DOI":"10.13039\/501100003107","name":"Bundesministerium f\u00fcr Gesundheit","doi-asserted-by":"crossref","award":["Bartonella consiliary laboratory"],"award-info":[{"award-number":["Bartonella consiliary laboratory"]}],"id":[{"id":"10.13039\/501100003107","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003107","name":"Bundesministerium f\u00fcr Gesundheit","doi-asserted-by":"crossref","award":["1369-354"],"award-info":[{"award-number":["1369-354"]}],"id":[{"id":"10.13039\/501100003107","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Parasites Vectors"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s13071-019-3390-2","type":"journal-article","created":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T20:04:56Z","timestamp":1553544296000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Carrion\u2019s disease: more than a neglected disease"],"prefix":"10.1186","volume":"12","author":[{"given":"Meritxell","family":"Garcia-Quintanilla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander A.","family":"Dichter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Humberto","family":"Guerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkhard A. J.","family":"Kempf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,3,26]]},"reference":[{"key":"3390_CR1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4269\/ajtmh.1997.57.174","volume":"57","author":"Y Amano","year":"1997","unstructured":"Amano Y, Rumbea J, Knobloch J, Olson J, Kron M. Bartonellosis in Ecuador: serosurvey and current status of cutaneous verrucous disease. Am J Trop Med Hyg. 1997;57:174\u20139.","journal-title":"Am J Trop Med Hyg."},{"key":"3390_CR2","first-page":"115","volume":"7","author":"SL Lydy","year":"2018","unstructured":"Lydy SL, Lascano MS, Garcia-Perez JE, Williams-Newkirk AJ, Grijalva MJ. Seroprevalence and risk factors for infection with Bartonella bacilliformis in Loja Province, Ecuador. Emerg Microbes Infect. 2018;7:115.","journal-title":"Emerg Microbes Infect"},{"key":"3390_CR3","doi-asserted-by":"crossref","first-page":"e00056","DOI":"10.1128\/CMR.00056-17","volume":"31","author":"C Gomes","year":"2018","unstructured":"Gomes C, Ruiz J. Carrion\u2019s disease: the sound of silence. Clin Microbiol Rev. 2018;31:e00056.","journal-title":"Clin Microbiol Rev."},{"key":"3390_CR4","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1086\/322614","volume":"33","author":"C Maguina","year":"2001","unstructured":"Maguina C, Garcia PJ, Gotuzzo E, Cordero L, Spach DH. Bartonellosis (Carrion\u02bcs disease) in the modern era. Clinical Infect Dis. 2001;33:772\u20139.","journal-title":"Clinical Infect Dis."},{"key":"3390_CR5","doi-asserted-by":"crossref","first-page":"e2919","DOI":"10.1371\/journal.pntd.0002919","volume":"8","author":"MF Minnick","year":"2014","unstructured":"Minnick MF, Anderson BE, Lima A, Battisti JM, Lawyer PG, Birtles RJ. Oroya fever and verruga peruana: bartonelloses unique to South America. PLoS Negl Trop Dis. 2014;8:e2919.","journal-title":"PLoS Negl Trop Dis."},{"key":"3390_CR6","doi-asserted-by":"crossref","first-page":"503","DOI":"10.4269\/ajtmh.1968.17.503","volume":"17","author":"MG Schultz","year":"1968","unstructured":"Schultz MG. A history of bartonellosis (Carrion\u02bcs disease). Am J Trop Med Hyg. 1968;17:503\u201315.","journal-title":"Am J Trop Med Hyg."},{"key":"3390_CR7","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s40249-016-0197-7","volume":"5","author":"C Gomes","year":"2016","unstructured":"Gomes C, Pons MJ, Del Valle Mendoza J, Ruiz J. Carrion\u02bcs disease: an eradicable illness? Infect Dis Poverty. 2016;5:105.","journal-title":"Infect Dis Poverty."},{"key":"3390_CR8","first-page":"303","volume":"215","author":"J Hong","year":"2017","unstructured":"Hong J, Li Y, Hua X, Bai Y, Wang C, Zhu C. Lymphatic circulation disseminates Bartonella infection into bloodstream. J Infect Dis. 2017;215:303\u201311.","journal-title":"J Infect Dis."},{"key":"3390_CR9","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1146\/annurev-ento-120811-153557","volume":"58","author":"PD Ready","year":"2013","unstructured":"Ready PD. Biology of phlebotomine sand flies as vectors of disease agents. Annu Rev Entomol. 2013;58:227\u201350.","journal-title":"Annu Rev Entomol."},{"key":"3390_CR10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ijmm.2010.06.004","volume":"301","author":"PO Kaiser","year":"2011","unstructured":"Kaiser PO, Riess T, O\u2019Rourke F, Linke D, Kempf VA. Bartonella spp.: throwing light on uncommon human infections. Int J Med Microbiol. 2011;301:7\u201315.","journal-title":"Int J Med Microbiol."},{"key":"3390_CR11","doi-asserted-by":"crossref","first-page":"431","DOI":"10.3389\/fcimb.2018.00431","volume":"8","author":"H Deng","year":"2018","unstructured":"Deng H, Pang Q, Zhao B, Vayssier-Taussat M. Molecular mechanisms of Bartonella and mammalian erythrocyte interactions: a review. Front Cell Infect Microbiol. 2018;8:431.","journal-title":"Front Cell Infect Microbiol."},{"key":"3390_CR12","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1099\/0022-1317-51-11-915","volume":"51","author":"G Greub","year":"2002","unstructured":"Greub G, Raoult D. Bartonella: new explanations for old diseases. J Med Microbiol. 2002;51:915\u201323.","journal-title":"J Med Microbiol."},{"key":"3390_CR13","doi-asserted-by":"crossref","first-page":"9247","DOI":"10.1073\/pnas.0502040102","volume":"102","author":"E Andersen-Nissen","year":"2005","unstructured":"Andersen-Nissen E, Smith KD, Strobe KL, Barrett SL, Cookson BT, Logan SM, et al. Evasion of Toll-like receptor 5 by flagellated bacteria. Proc Natl Acad Sci USA. 2005;102:9247\u201352.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3390_CR14","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.tim.2006.04.005","volume":"14","author":"D Linke","year":"2006","unstructured":"Linke D, Riess T, Autenrieth IB, Lupas A, Kempf VA. Trimeric autotransporter adhesins: variable structure, common function. Trends Microbiol. 2006;14:264\u201370.","journal-title":"Trends Microbiol."},{"key":"3390_CR15","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1126\/science.38.971.194","volume":"38","author":"CH Townsend","year":"1913","unstructured":"Townsend CH. A Phlebotomus the practically certain carrier of verruga. Science. 1913;38:194\u20135.","journal-title":"Science."},{"key":"3390_CR16","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1084\/jem.49.6.993","volume":"49","author":"H Noguchi","year":"1929","unstructured":"Noguchi H, Shannon RC, Tilden EB, Tyler JR. Etiology of Oroya fever: XIV. The insect vectors of Carrion\u02bcs disease. J Exp Med. 1929;49:993\u20131008.","journal-title":"J Exp Med."},{"key":"3390_CR17","doi-asserted-by":"crossref","first-page":"354","DOI":"10.4269\/ajtmh.1995.52.354","volume":"52","author":"B Alexander","year":"1995","unstructured":"Alexander B. A review of bartonellosis in Ecuador and Colombia. Am J Trop Med Hyg. 1995;52:354\u20139.","journal-title":"Am J Trop Med Hyg."},{"key":"3390_CR18","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.4269\/ajtmh.18-0520","volume":"99","author":"GM Ulloa","year":"2018","unstructured":"Ulloa GM, Vasquez-Achaya F, Gomes C, Del Valle LJ, Ruiz J, Pons MJ, et al. Molecular detection of Bartonella bacilliformis in Lutzomyia maranonensis in Cajamarca, Peru: a new potential vector of Carrion\u02bcs disease in Peru? Am J Trop Med Hyg. 2018;99:1229\u201333.","journal-title":"Am J Trop Med Hyg."},{"key":"3390_CR19","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/mve.12219","volume":"31","author":"DA Moo-Llanes","year":"2017","unstructured":"Moo-Llanes DA, Arque-Chunga W, Carmona-Castro O, Yanez-Arenas C, Yanez-Trujillano HH, Cheverria-Pacheco L, et al. Shifts in the ecological niche of Lutzomyia peruensis under climate change scenarios in Peru. Med Vet Entomol. 2017;31:123\u201331.","journal-title":"Med Vet Entomol."},{"key":"3390_CR20","first-page":"28","volume":"15","author":"P Villaseca","year":"1999","unstructured":"Villaseca P, Padilla C, Ventura G, Samalvides F, Ya\u00f1ez H, Chevarr\u00eda L, et al. Importancia de la Lutzomyia peruensis en la transmisi\u00f3n de la enfermedad de Carri\u00f3n en el valle Sagrado de los Incas. Urubamba-Cusco, Peru. Rev Med Exp. 1999;15:28\u201330.","journal-title":"Rev Med Exp."},{"key":"3390_CR21","doi-asserted-by":"crossref","first-page":"348","DOI":"10.17843\/rpmesp.2014.312.57","volume":"31","author":"C Maguina-Vargas","year":"2014","unstructured":"Maguina-Vargas C, Pachas P. Experiences in the prevention and control of Carrion\u02bcs disease in Peru. Rev Peru Med Exp Salud Publica. 2014;31:348\u201351.","journal-title":"Rev Peru Med Exp Salud Publica."},{"key":"3390_CR22","unstructured":"Romero S. Detection of Bartonella bacilliformis by real-time PCR in naturally infected sand flies. Thesis. Department of Preventive Medicine and Biometrics, University of the Health Sciences. Bethesda, MD, 2004. https:\/\/apps.dtic.mil\/dtic\/tr\/fulltext\/u2\/a434804.pdf . Accessed 19 Dec 2018."},{"key":"3390_CR23","unstructured":"Carrazco-Montalvo AR. Detecci\u00f3n molecular de Bartonella bacilliformis en fleb\u00f3tomos (Diptera: Psychodidae) en la zona fronteriza ecuatoriana-peruana. Thesis. Colegio de Ciencia Biol\u00f3gicas y Ambientales, University of San Francisco de Quito USFQ. Ecuador, 2017. http:\/\/repositorio.usfq.edu.ec\/bitstream\/23000\/6480\/1\/131141.pdf . Accessed 30 Jan 2018."},{"key":"3390_CR24","doi-asserted-by":"crossref","first-page":"e0004128","DOI":"10.1371\/journal.pntd.0004128","volume":"9","author":"JM Battisti","year":"2015","unstructured":"Battisti JM, Lawyer PG, Minnick MF. Colonization of Lutzomyia verrucarum and Lutzomyia longipalpis sand flies (Diptera: Psychodidae) by Bartonella bacilliformis, the etiologic agent of Carrion\u2019s disease. PLoS Negl Trop Dis. 2015;9:e0004128.","journal-title":"PLoS Negl Trop Dis."},{"key":"3390_CR25","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1590\/S0036-46651993000600002","volume":"35","author":"AG Caceres","year":"1993","unstructured":"Caceres AG. Geographic distribution of Lutzomyia verrucarum (Townsend, 1913) (Diptera, Psychodidae, Phlebotominae), vector of human bartonellosis in Peru. Rev Inst Med Trop Sao Paulo. 1993;35:485\u201390.","journal-title":"Rev Inst Med Trop Sao Paulo."},{"key":"3390_CR26","doi-asserted-by":"crossref","first-page":"3675","DOI":"10.1128\/JCM.42.8.3675-3680.2004","volume":"42","author":"TM Hambuch","year":"2004","unstructured":"Hambuch TM, Handley SA, Ellis B, Chamberlin J, Romero S, Regnery R. Population genetic analysis of Bartonella bacilliformis isolates from areas of Peru where Carrion\u02bcs disease is endemic and epidemic. J Clin Microbiol. 2004;42:3675\u201380.","journal-title":"J Clin Microbiol."},{"key":"3390_CR27","doi-asserted-by":"crossref","first-page":"485","DOI":"10.17843\/rpmesp.2017.343.2398","volume":"34","author":"V Zorrilla","year":"2017","unstructured":"Zorrilla V, V\u00e1squez G, Espada L, Ram\u00edrez P. Vectores de la leishmaniasis tegumentaria y la enfermedad de Carri\u00f3n en el Per\u00fa: una actualizacion. Rev Peru Med Exp Salud Publica. 2017;34:485\u201396.","journal-title":"Rev Peru Med Exp Salud Publica."},{"key":"3390_CR28","first-page":"e3528","volume":"10","author":"LC Urrutia","year":"2018","unstructured":"Urrutia LC, Patino-Barbosa AM, Arroyave-Valencia F, Sabogal-Roman JA, Cardona-Ospina JA, Rodriguez-Morales AJ. Oroya fever, verruga peruana, and other bartonelloses incidence rates in Colombia (2009\u20132013). Cureus. 2018;10:e3528.","journal-title":"Cureus."},{"key":"3390_CR29","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1084\/jem.44.5.729","volume":"44","author":"H Noguchi","year":"1926","unstructured":"Noguchi H. Etiology of Oroya fever: V. The experimental transmission of Bartonella bacilliformis by ticks (Dermacentor andersoni). J Exp Med. 1926;44:729\u201334.","journal-title":"J Exp Med."},{"key":"3390_CR30","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1186\/s13104-018-3518-z","volume":"11","author":"J Valle-Mendoza Del","year":"2018","unstructured":"Del Valle-Mendoza J, Rojas-Jaimes J, Vasquez-Achaya F, Aguilar-Luis MA, Correa-Nunez G, Silva-Caso W, et al. Molecular identification of Bartonella bacilliformis in ticks collected from two species of wild mammals in Madre de Dios: Peru. BMC Res Notes. 2018;11:405.","journal-title":"BMC Res Notes."},{"key":"3390_CR31","doi-asserted-by":"crossref","first-page":"e0005297","DOI":"10.1371\/journal.pntd.0005297","volume":"11","author":"M Laroche","year":"2017","unstructured":"Laroche M, Berenger JM, Mediannikov O, Raoult D, Parola P. Detection of a potential new Bartonella species \u201cCandidatus Bartonella rondoniensis\u201d in human biting kissing bugs (Reduviidae; Triatominae). PLoS Negl Trop Dis. 2017;11:e0005297.","journal-title":"PLoS Negl Trop Dis."},{"key":"3390_CR32","doi-asserted-by":"crossref","first-page":"3339","DOI":"10.1099\/ijsem.0.000416","volume":"65","author":"KE Mullins","year":"2015","unstructured":"Mullins KE, Hang J, Jiang J, Leguia M, Kasper MR, Ventosilla P, et al. Description of Bartonella ancashensis sp. nov., isolated from the blood of two patients with verruga peruana. Int J Syst Evol Microbiol. 2015;65:3339\u201343.","journal-title":"Int J Syst Evol Microbiol."},{"key":"3390_CR33","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s13071-017-2042-7","volume":"10","author":"Y Regier","year":"2017","unstructured":"Regier Y, Ballhorn W, Kempf VA. Molecular detection of Bartonella henselae in 11 Ixodes ricinus ticks extracted from a single cat. Parasit Vectors. 2017;10:105.","journal-title":"Parasit Vectors."},{"key":"3390_CR34","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1128\/CMR.13.3.428","volume":"13","author":"EB Breitschwerdt","year":"2000","unstructured":"Breitschwerdt EB, Kordick DL. Bartonella infection in animals: carriership, reservoir potential, pathogenicity, and zoonotic potential for human infection. Clin Microbiol Rev. 2000;13:428\u201338.","journal-title":"Clin Microbiol Rev."},{"key":"3390_CR35","doi-asserted-by":"crossref","first-page":"799","DOI":"10.4269\/ajtmh.1999.60.799","volume":"60","author":"RJ Birtles","year":"1999","unstructured":"Birtles RJ, Canales J, Ventosilla P, Alvarez E, Guerra H, Llanos-Cuentas A, et al. Survey of Bartonella species infecting intradomicillary animals in the Huayllacallan Valley, Ancash, Peru, a region endemic for human bartonellosis. Am J Trop Med Hyg. 1999;60:799\u2013805.","journal-title":"Am J Trop Med Hyg."},{"key":"3390_CR36","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.tplants.2012.03.007","volume":"17","author":"A Schikora","year":"2012","unstructured":"Schikora A, Garcia AV, Hirt H. Plants as alternative hosts for Salmonella. Trends Plant Sci. 2012;17:245\u20139.","journal-title":"Trends Plant Sci."},{"key":"3390_CR37","first-page":"269","volume":"413","author":"C Dehio","year":"2017","unstructured":"Dehio C, Tsolis RM. Type IV effector secretion and subversion of host functions by Bartonella and Brucella species. Curr Top Microbiol Immunol. 2017;413:269\u201395.","journal-title":"Curr Top Microbiol Immunol."},{"key":"3390_CR38","doi-asserted-by":"crossref","first-page":"637","DOI":"10.4269\/ajtmh.1953.2.637","volume":"2","author":"A Herrer","year":"1953","unstructured":"Herrer A. Carrion\u02bcs disease. I. Studies on plants claimed to be reservoirs of Bartonella bacilliformis. Am J Trop Med Hyg. 1953;2:637\u201343.","journal-title":"Am J Trop Med Hyg."},{"key":"3390_CR39","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1038\/ismej.2016.201","volume":"11","author":"FH Segers","year":"2017","unstructured":"Segers FH, Kesnerova L, Kosoy M, Engel P. Genomic changes associated with the evolutionary transition of an insect gut symbiont into a blood-borne pathogen. ISME J. 2017;11:1232\u201344.","journal-title":"ISME J."},{"key":"3390_CR40","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000235769","volume":"6","author":"P Engel","year":"2009","unstructured":"Engel P, Dehio C. Genomics of host-restricted pathogens of the genus Bartonella. Genome Dyn. 2009;6:158\u201369.","journal-title":"Genome Dyn."},{"key":"3390_CR41","doi-asserted-by":"crossref","first-page":"4837","DOI":"10.1128\/IAI.63.12.4837-4848.1995","volume":"63","author":"JC Pepe","year":"1995","unstructured":"Pepe JC, Wachtel MR, Wagar E, Miller VL. Pathogenesis of defined invasion mutants of Yersinia enterocolitica in a BALB\/c mouse model of infection. Infect Immun. 1995;63:4837\u201348.","journal-title":"Infect Immun."},{"key":"3390_CR42","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1084\/jem.20020407","volume":"195","author":"M Comanducci","year":"2002","unstructured":"Comanducci M, Bambini S, Brunelli B, Adu-Bobie J, Arico B, Capecchi B, et al. NadA, a novel vaccine candidate of Neisseria meningitidis. J Exp Med. 2002;195:1445\u201354.","journal-title":"J Exp Med."},{"key":"3390_CR43","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1462-5822.2011.01711.x","volume":"14","author":"PO Kaiser","year":"2012","unstructured":"Kaiser PO, Linke D, Schwarz H, Leo JC, Kempf VA. Analysis of the BadA stalk from Bartonella henselae reveals domain-specific and domain-overlapping functions in the host cell infection process. Cell Microbiol. 2012;14:198\u2013209.","journal-title":"Cell Microbiol."},{"key":"3390_CR44","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1111\/j.1462-5822.2008.01201.x","volume":"10","author":"PO Kaiser","year":"2008","unstructured":"Kaiser PO, Riess T, Wagner CL, Linke D, Lupas AN, Schwarz H, et al. The head of Bartonella adhesin A is crucial for host cell interaction of Bartonella henselae. Cell Microbiol. 2008;10:2223\u201334.","journal-title":"Cell Microbiol."},{"key":"3390_CR45","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1084\/jem.20040500","volume":"200","author":"T Riess","year":"2004","unstructured":"Riess T, Andersson SG, Lupas A, Schaller M, Schafer A, Kyme P, et al. Bartonella adhesin a mediates a proangiogenic host cell response. J Exp Med. 2004;200:1267\u201378.","journal-title":"J Exp Med."},{"key":"3390_CR46","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1128\/IAI.54.2.347-353.1986","volume":"54","author":"LA Benson","year":"1986","unstructured":"Benson LA, Kar S, McLaughlin G, Ihler GM. Entry of Bartonella bacilliformis into erythrocytes. Infect Immun. 1986;54:347\u201353.","journal-title":"Infect Immun."},{"key":"3390_CR47","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1128\/IAI.60.3.937-943.1992","volume":"60","author":"G Mernaugh","year":"1992","unstructured":"Mernaugh G, Ihler GM. Deformation factor: an extracellular protein synthesized by Bartonella bacilliformis that deforms erythrocyte membranes. Infect Immun. 1992;60:937\u201343.","journal-title":"Infect Immun."},{"key":"3390_CR48","doi-asserted-by":"crossref","first-page":"4962","DOI":"10.1128\/IAI.61.12.4962-4971.1993","volume":"61","author":"DC Scherer","year":"1993","unstructured":"Scherer DC, DeBuron-Connors I, Minnick MF. Characterization of Bartonella bacilliformis flagella and effect of antiflagellin antibodies on invasion of human erythrocytes. Infect Immun. 1993;61:4962\u201371.","journal-title":"Infect Immun."},{"key":"3390_CR49","doi-asserted-by":"crossref","first-page":"e0004391","DOI":"10.1371\/journal.pntd.0004391","volume":"10","author":"MJ Pons","year":"2016","unstructured":"Pons MJ, Silva-Caso W, Del Valle-Mendoza J, Ruiz J. Multi-locus sequence typing of Bartonella bacilliformis DNA performed directly from blood of patients with Oroya\u02bcs fever during a Peruvian outbreak. PLoS Negl Trop Dis. 2016;10:e0004391.","journal-title":"PLoS Negl Trop Dis."},{"key":"3390_CR50","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1099\/00207713-52-1-165","volume":"52","author":"Z Zeaiter","year":"2002","unstructured":"Zeaiter Z, Fournier PE, Ogata H, Raoult D. Phylogenetic classification of Bartonella species by comparing groEL sequences. Int J Syst Evol Microbiol. 2002;52:165\u201371.","journal-title":"Int J Syst Evol Microbiol."},{"key":"3390_CR51","doi-asserted-by":"crossref","first-page":"e0004989","DOI":"10.1371\/journal.pntd.0004989","volume":"10","author":"C Gomes","year":"2016","unstructured":"Gomes C, Palma N, Pons MJ, Magallon-Tejada A, Sandoval I, Tinco-Valdez C, et al. Succinyl-CoA Synthetase: new antigen candidate of Bartonella bacilliformis. PLoS Negl Trop Dis. 2016;10:e0004989.","journal-title":"PLoS Negl Trop Dis."},{"key":"3390_CR52","doi-asserted-by":"crossref","first-page":"6933","DOI":"10.1128\/IAI.71.12.6933-6942.2003","volume":"71","author":"MF Minnick","year":"2003","unstructured":"Minnick MF, Smitherman LS, Samuels DS. Mitogenic effect of Bartonella bacilliformis on human vascular endothelial cells and involvement of GroEL. Infect Immun. 2003;71:6933\u201342.","journal-title":"Infect Immun."},{"key":"3390_CR53","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1128\/IAI.60.5.2125-2127.1992","volume":"60","author":"DJ Evans Jr","year":"1992","unstructured":"Evans DJ Jr, Evans DG, Engstrand L, Graham DY. Urease-associated heat shock protein of Helicobacter pylori. Infect Immun. 1992;60:2125\u20137.","journal-title":"Infect Immun."},{"key":"3390_CR54","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1128\/IAI.66.3.1023-1027.1998","volume":"66","author":"A Vanet","year":"1998","unstructured":"Vanet A, Labigne A. Evidence for specific secretion rather than autolysis in the release of some Helicobacter pylori proteins. Infect Immun. 1998;66:1023\u20137.","journal-title":"Infect Immun."},{"key":"3390_CR55","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.gene.2005.06.031","volume":"359","author":"JA Callison","year":"2005","unstructured":"Callison JA, Battisti JM, Sappington KN, Smitherman LS, Minnick MF. Characterization and expression analysis of the groESL operon of Bartonella bacilliformis. Gene. 2005;359:53\u201362.","journal-title":"Gene."},{"key":"3390_CR56","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1196\/annals.1355.046","volume":"1063","author":"LS Smitherman","year":"2005","unstructured":"Smitherman LS, Minnick MF. Bartonella bacilliformis GroEL: effect on growth of human vascular endothelial cells in infected cocultures. Ann N Y Acad Sci. 2005;1063:286\u201398.","journal-title":"Ann N Y Acad Sci."},{"key":"3390_CR57","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1196\/annals.1355.045","volume":"1063","author":"A Taye","year":"2005","unstructured":"Taye A, Chen H, Duncan K, Zhang Z, Hendrix L, Gonzalez J, et al. Production of recombinant protein Pap31 and its application for the diagnosis of Bartonella bacilliformis infection. Ann N Y Acad Sci. 2005;1063:280\u20135.","journal-title":"Ann N Y Acad Sci."},{"key":"3390_CR58","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1128\/JB.185.5.1739-1744.2003","volume":"185","author":"R Zimmermann","year":"2003","unstructured":"Zimmermann R, Kempf VA, Schiltz E, Oberle K, Sander A. Hemin binding, functional expression, and complementation analysis of Pap 31 from Bartonella henselae. J Bacteriol. 2003;185:1739\u201344.","journal-title":"J Bacteriol."},{"key":"3390_CR59","doi-asserted-by":"crossref","first-page":"702784","DOI":"10.1155\/2015\/702784","volume":"2015","author":"C Henriquez-Camacho","year":"2015","unstructured":"Henriquez-Camacho C, Ventosilla P, Minnick MF, Ruiz J, Maguina C. Proteins of Bartonella bacilliformis: candidates for vaccine development. Int J Pept. 2015;2015:702784.","journal-title":"Int J Pept."},{"key":"3390_CR60","first-page":"76","volume":"58","author":"DE Bentzel","year":"2008","unstructured":"Bentzel DE, Espinosa BJ, Canal E, Blazes DL, Hall ER. Susceptibility of owl monkeys (Aotus nancymaae) to experimental infection with Bartonella bacilliformis. Comp Med. 2008;58:76\u201380.","journal-title":"Comp Med."},{"key":"3390_CR61","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1128\/IAI.63.4.1552-1562.1995","volume":"63","author":"SJ Mitchell","year":"1995","unstructured":"Mitchell SJ, Minnick MF. Characterization of a two-gene locus from Bartonella bacilliformis associated with the ability to invade human erythrocytes. Infect Iimmun. 1995;63:1552\u201362.","journal-title":"Infect Iimmun."},{"key":"3390_CR62","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1128\/IAI.56.5.1242-1248.1988","volume":"56","author":"VL Miller","year":"1988","unstructured":"Miller VL, Falkow S. Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of epithelial cells. Infect Immun. 1988;56:1242\u20138.","journal-title":"Infect Immun."},{"key":"3390_CR63","first-page":"15","volume":"138","author":"VL Miller","year":"1988","unstructured":"Miller VL, Finlay BB, Falkow S. Factors essential for the penetration of mammalian cells by Yersinia. Curr Top Microbiol Immunol. 1988;138:15\u201339.","journal-title":"Curr Top Microbiol Immunol."},{"key":"3390_CR64","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1074\/jbc.274.3.1203","volume":"274","author":"GB Conyers","year":"1999","unstructured":"Conyers GB, Bessman MJ. The gene, ialA, associated with the invasion of human erythrocytes by Bartonella bacilliformis, designates a nudix hydrolase active on dinucleoside 5\u2019-polyphosphates. J Biol Chem. 1999;274:1203\u20136.","journal-title":"J Biol Chem."},{"key":"3390_CR65","doi-asserted-by":"crossref","first-page":"4373","DOI":"10.1128\/IAI.69.7.4373-4381.2001","volume":"69","author":"SA Coleman","year":"2001","unstructured":"Coleman SA, Minnick MF. Establishing a direct role for the Bartonella bacilliformis invasion-associated locus B (IalB) protein in human erythrocyte parasitism. Infect Immun. 2001;69:4373\u201381.","journal-title":"Infect Immun."},{"key":"3390_CR66","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0882-4010(03)00005-6","volume":"34","author":"SA Coleman","year":"2003","unstructured":"Coleman SA, Minnick MF. Differential expression of the invasion-associated locus B (ialB) gene of Bartonella bacilliformis in response to environmental cues. Microb Pathog. 2003;34:179\u201386.","journal-title":"Microb Pathog."},{"key":"3390_CR67","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1006\/bcmd.2001.0475","volume":"27","author":"SC Derrick","year":"2001","unstructured":"Derrick SC, Ihler GM. Deformin, a substance found in Bartonella bacilliformis culture supernatants, is a small, hydrophobic molecule with an affinity for albumin. Blood Cells Mol Dis. 2001;27:1013\u20139.","journal-title":"Blood Cells Mol Dis."},{"key":"3390_CR68","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1574-6968.2000.tb08884.x","volume":"182","author":"LR Hendrix","year":"2000","unstructured":"Hendrix LR. Contact-dependent hemolytic activity distinct from deforming activity of Bartonella bacilliformis. FEMS Microbiol Lett. 2000;182:119\u201324.","journal-title":"FEMS Microbiol Lett."},{"key":"3390_CR69","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1574-6968.1997.tb12775.x","volume":"157","author":"S Iwaki-Egawa","year":"1997","unstructured":"Iwaki-Egawa S, Ihler GM. Comparison of the abilities of proteins from Bartonella bacilliformis and Bartonella henselae to deform red cell membranes and to bind to red cell ghost proteins. FEMS Microbiol Lett. 1997;157:207\u201317.","journal-title":"FEMS Microbiol Lett."},{"key":"3390_CR70","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1006\/mpat.2000.0381","volume":"29","author":"EL Buckles","year":"2000","unstructured":"Buckles EL, McGinnis-Hill E. Interaction of Bartonella bacilliformis with human erythrocyte membrane proteins. Microb Pathog. 2000;29:165\u201374.","journal-title":"Microb Pathog."},{"key":"3390_CR71","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1128\/IAI.31.1.480-486.1981","volume":"31","author":"TS Walker","year":"1981","unstructured":"Walker TS, Winkler HH. Bartonella bacilliformis: colonial types and erythrocyte adherence. Infect Immun. 1981;31:480\u20136.","journal-title":"Infect Immun."},{"key":"3390_CR72","doi-asserted-by":"crossref","first-page":"4051","DOI":"10.1128\/IAI.60.10.4051-4058.1992","volume":"60","author":"EM Hill","year":"1992","unstructured":"Hill EM, Raji A, Valenzuela MS, Garcia F, Hoover R. Adhesion to and invasion of cultured human cells by Bartonella bacilliformis. Infect Immun. 1992;60:4051\u20138.","journal-title":"Infect Immun."},{"key":"3390_CR73","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1093\/infdis\/165.6.1138","volume":"165","author":"FU Garcia","year":"1992","unstructured":"Garcia FU, Wojta J, Hoover RL. Interactions between live Bartonella bacilliformis and endothelial cells. J Infect Dis. 1992;165:1138\u201341.","journal-title":"J Infect Dis."},{"key":"3390_CR74","doi-asserted-by":"crossref","first-page":"5960","DOI":"10.1128\/IAI.68.10.5960-5969.2000","volume":"68","author":"A Verma","year":"2000","unstructured":"Verma A, Davis GE, Ihler GM. Infection of human endothelial cells with Bartonella bacilliformis is dependent on Rho and results in activation of Rho. Infect Immun. 2000;68:5960\u20139.","journal-title":"Infect Immun."},{"key":"3390_CR75","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1046\/j.1462-5822.2001.00104.x","volume":"3","author":"A Verma","year":"2001","unstructured":"Verma A, Davis GE, Ihler GM. Formation of stress fibres in human endothelial cells infected with Bartonella bacilliformis is associated with altered morphology, impaired migration and defects in cell morphogenesis. Cell Microbiol. 2001;3:169\u201380.","journal-title":"Cell Microbiol."},{"key":"3390_CR76","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1046\/j.1462-5822.2002.00217.x","volume":"4","author":"A Verma","year":"2002","unstructured":"Verma A, Ihler GM. Activation of Rac, Cdc42 and other downstream signalling molecules by Bartonella bacilliformis during entry into human endothelial cells. Cellr Microbiol. 2002;4:557\u201369.","journal-title":"Cellr Microbiol."},{"key":"3390_CR77","first-page":"1125","volume":"136","author":"FU Garcia","year":"1990","unstructured":"Garcia FU, Wojta J, Broadley KN, Davidson JM, Hoover RL. Bartonella bacilliformis stimulates endothelial cells in vitro and is angiogenic in vivo. Am J Pathol. 1990;136:1125\u201335.","journal-title":"Am J Pathol."},{"key":"3390_CR78","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/S0002-9440(10)63491-8","volume":"163","author":"F Cerimele","year":"2003","unstructured":"Cerimele F, Brown LF, Bravo F, Ihler GM, Kouadio P, Arbiser JL. Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of angiopoetin-2 and epidermal production of vascular endothelial growth factor. Am J Pathol. 2003;163:1321\u20137.","journal-title":"Am J Pathol."},{"key":"3390_CR79","doi-asserted-by":"crossref","unstructured":"Noguchi H, Battistini TS. Etiology of Oroya fever: I. Cultivation of Bartonella bacilliformis. J Exp Med. 1926;43:851\u201364.","DOI":"10.1084\/jem.43.6.851"},{"key":"3390_CR80","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1084\/jem.44.5.697","volume":"44","author":"H Noguchi","year":"1926","unstructured":"Noguchi H. Etiology of Oroya fever: III The behavior of Bartonella bacilliformis in Macacus rhesus. J Exp Med. 1926;44:697\u2013713.","journal-title":"J Exp Med."},{"key":"3390_CR81","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1084\/jem.45.5.781","volume":"45","author":"H Noguchi","year":"1927","unstructured":"Noguchi H. Etiology of Oroya fever: VIII. Experiments on cross-immunity between Oroya fever and verruga peruana. J Exp Med. 1927;45:781\u20133.","journal-title":"J Exp Med."},{"key":"3390_CR82","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1084\/jem.47.2.219","volume":"47","author":"H Noguchi","year":"1928","unstructured":"Noguchi H. Etiology of Oroya fever: X. Comparative studies of different strains of Bartonella bacilliformis, with special reference to the relationship between the clinical types of Carrion\u02bcs disease and the virulence of the infecting organism. J Exp Med. 1928;47:219\u201334.","journal-title":"J Exp Med."},{"key":"3390_CR83","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1084\/jem.44.5.715","volume":"44","author":"H Noguchi","year":"1926","unstructured":"Noguchi H. Etiology of Oroya fever: IV. The effect of inoculation of anthropoid apes with Bartonella bacilliformis. J Exp Med. 1926;44:715\u201328.","journal-title":"J Exp Med."},{"key":"3390_CR84","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1084\/jem.50.4.455","volume":"50","author":"H Noguchi","year":"1929","unstructured":"Noguchi H, Muller HR, Tilden EB, Tyler JR. Etiology of Oroya fever: XVI. Verruga in the dog and the donkey. J Exp Med. 1929;50:455\u201361.","journal-title":"J Exp Med."},{"key":"3390_CR85","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/1756-0500-1-103","volume":"1","author":"B Infante","year":"2008","unstructured":"Infante B, Villar S, Palma S, Merello J, Valencia R, Torres L, et al. BALB\/c mice resist infection with Bartonella bacilliformis. BMC Res Notes. 2008;1:103.","journal-title":"BMC Res Notes."},{"key":"3390_CR86","doi-asserted-by":"crossref","first-page":"e1000946","DOI":"10.1371\/journal.ppat.1000946","volume":"6","author":"M Vayssier-Taussat","year":"2010","unstructured":"Vayssier-Taussat M, Le Rhun D, Deng HK, Biville F, Cescau S, Danchin A, et al. The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS Pathog. 2010;6:e1000946.","journal-title":"PLoS Pathog."},{"key":"3390_CR87","doi-asserted-by":"crossref","first-page":"e0129825","DOI":"10.1371\/journal.pone.0129825","volume":"10","author":"A Amaladoss","year":"2015","unstructured":"Amaladoss A, Chen Q, Liu M, Dummler SK, Dao M, Suresh S, et al. De novo generated human red blood cells in humanized mice support Plasmodium falciparum infection. PloS One. 2015;10:e0129825.","journal-title":"PloS One."},{"key":"3390_CR88","doi-asserted-by":"crossref","first-page":"e0005684","DOI":"10.1371\/journal.pntd.0005684","volume":"11","author":"MJ Pons","year":"2017","unstructured":"Pons MJ, Gomes C, Aguilar R, Barrios D, Aguilar-Luis MA, Ruiz J, et al. Immunosuppressive and angiogenic cytokine profile associated with Bartonella bacilliformis infection in post-outbreak and endemic areas of Carrion\u02bcs disease in Peru. PLoS Negl Trop Dis. 2017;11:e0005684.","journal-title":"PLoS Negl Trop Dis."},{"key":"3390_CR89","doi-asserted-by":"crossref","unstructured":"Noguchi H, Muller HR, Tilden EB, Tyler JR. Etiology of Oroya fever: XV. Effect of immune serum on the course of Bartonella bacilliformis infection in Macacus rhesus. J Exp Med. 1929;50:355\u201364.","DOI":"10.1084\/jem.50.3.355"},{"key":"3390_CR90","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1615\/CritRevImmunol.v32.i1.30","volume":"32","author":"SS Iyer","year":"2012","unstructured":"Iyer SS, Cheng G. Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit Rev Immunol. 2012;32:23\u201363.","journal-title":"Crit Rev Immunol."},{"key":"3390_CR91","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1590\/S0036-46652007000500012","volume":"49","author":"E Huarcaya","year":"2007","unstructured":"Huarcaya E, Maguina C, Best I, Solorzano N, Leeman L. Immunological response in cases of complicated and uncomplicated bartonellosis during pregnancy. Rev Inst Med Trop Sao Paulo. 2007;49:335\u20137.","journal-title":"Rev Inst Med Trop Sao Paulo."},{"key":"3390_CR92","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1046\/j.1462-5822.2001.00144.x","volume":"3","author":"VA Kempf","year":"2001","unstructured":"Kempf VA, Volkmann B, Schaller M, Sander CA, Alitalo K, Riess T, et al. Evidence of a leading role for VEGF in Bartonella henselae-induced endothelial cell proliferations. Cell Microbiol. 2001;3:623\u201332.","journal-title":"Cell Microbiol."},{"key":"3390_CR93","doi-asserted-by":"crossref","first-page":"7571","DOI":"10.4049\/jimmunol.166.12.7571","volume":"166","author":"R Salcedo","year":"2001","unstructured":"Salcedo R, Young HA, Ponce ML, Ward JM, Kleinman HK, Murphy WJ, et al. Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells. J Immunol. 2001;166:7571\u20138.","journal-title":"J Immunol."},{"key":"3390_CR94","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.reper.2016.02.013","volume":"25","author":"HA Sotomayor-Trib\u00edn","year":"2016","unstructured":"Sotomayor-Trib\u00edn HA. Pensamiento anal\u00f3gico m\u00edtico en la interpretaci\u00f3n del arte prehisp\u00e1nico de inter\u00e9s para la arqueomedicina y la paleopatolog\u00eda. Repert Med Cir. 2016;25:50\u201371.","journal-title":"Repert Med Cir."},{"key":"3390_CR95","doi-asserted-by":"crossref","first-page":"5224","DOI":"10.1128\/AEM.00621-08","volume":"74","author":"T Riess","year":"2008","unstructured":"Riess T, Dietrich F, Schmidt KV, Kaiser PO, Schwarz H, Schafer A, et al. Analysis of a novel insect cell culture medium-based growth medium for Bartonella species. Appl Environ Microbiol. 2008;74:5224\u20137.","journal-title":"Appl Environ Microbiol."}],"container-title":["Parasites &amp; Vectors"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13071-019-3390-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13071-019-3390-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13071-019-3390-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T06:19:54Z","timestamp":1663136394000},"score":1,"resource":{"primary":{"URL":"https:\/\/parasitesandvectors.biomedcentral.com\/articles\/10.1186\/s13071-019-3390-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,26]]},"references-count":95,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["3390"],"URL":"https:\/\/doi.org\/10.1186\/s13071-019-3390-2","relation":{},"ISSN":["1756-3305"],"issn-type":[{"value":"1756-3305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,26]]},"assertion":[{"value":"19 December 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"141"}}