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Ethical clearance of the study was provided by the Joint Research Ethics Committee (JREC) for the University of Zimbabwe, College Of Health Sciences and the Parirenyatwa Group of Hospitals (JREC\/251\/16). Further approval was provided by the National Ethical Review Board, the Medical Research Council of Zimbabwe (MRCZ) (MRCZ\/A\/2149). Visits were made to the various communities in the area, engaging the village heads and village health workers in the communities. The parents were sensitized about the nature of the study and study objectives in local language (Shona). Written informed consent in the local language was obtained from caregivers for both their enrolment and enrolment of their children into the study. Participation was entirely voluntary and only participants with signed informed consent forms were enrolled into the study.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"427"}}