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This systematic review was performed to provide insight into the progress made by the national STH and SCH control programme purposed with reaching these targets.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Studies published on STH and SCH in Ethiopia were searched for using Web of Science, PubMed, Scopus, and the resulting references of selected studies. Prevalence and intensity were analysed, stratified by region, age, and diagnostics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 231 papers published between 2000 and 2020 were included. Over the past two decades,<jats:italic>Trichuris trichiura<\/jats:italic>(TT) infection has shown the most statistically significant decrease (93%,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), followed by<jats:italic>Schistosoma mansoni<\/jats:italic>(SM) (69%,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001),<jats:italic>Ascaris lumbricoides<\/jats:italic>(AL) (67%,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) and<jats:italic>Schistosoma haematobium<\/jats:italic>(83%,<jats:italic>p<\/jats:italic>\u2009=\u20090.038) infections. Geographically, parasite burden has only consistently shown a significant reduction in the Southern Nations, Nationalities and Peoples\u2019 Region of Ethiopia, where AL, TT, hookworm and SM significantly decreased by 80% (<jats:italic>p<\/jats:italic>\u2009=\u20090.006), 95% (<jats:italic>p<\/jats:italic>\u2009=\u20090.005), 98% (<jats:italic>p<\/jats:italic>\u2009=\u20090.009) and 87% (<jats:italic>p<\/jats:italic>\u2009=\u20090.031), respectively. Prevalence of STH was highest among adults across all species, contrary to typical age-infection profiles for TT and AL that peak among school-aged children. Expanding treatment to the whole community would target reservoirs of adult and preschool-aged infection within the community, assisting Ethiopia in reaching\u00a0their national transmission break targets. There was substantial heterogeneity in diagnostic methods used across studies, the majority of which predominantly used single-slide Kato\u2013Katz. This low slide frequency provides poor\u00a0diagnostic sensitivity, particularly in low endemic settings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of STH and SCH in Ethiopia has decreased over time due to the strategic use of anthelmintics. Both standardising and increasing the sensitivity of the diagnostics used, alongside the ubiquitous use of parasite intensity with prevalence, would enable a more accurate and comparable understanding of Ethiopia\u2019s epidemiological progress. Further work is needed on community-wide surveillance in order to understand the burden and subsequent need for treatment among those outside of the standard school-based control program.<\/jats:p><\/jats:sec><jats:sec><jats:title>Graphical Abstract<\/jats:title><\/jats:sec>","DOI":"10.1186\/s13071-021-04600-0","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T13:08:27Z","timestamp":1612530507000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Soil-transmitted helminths and schistosome infections in Ethiopia: a systematic review of progress in their control over the past 20 years"],"prefix":"10.1186","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9363-3103","authenticated-orcid":false,"given":"Rosie","family":"Maddren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Ower","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toby","family":"Landeryou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birhan","family":"Mengistu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ufaysa","family":"Anjulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewnetu","family":"Firdawek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebiyu","family":"Negussu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"key":"4600_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1473-3099(15)00504-6","volume":"16","author":"DH Molyneux","year":"2016","unstructured":"Molyneux DH, Savioli L, Engels D. 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