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The aim of this review is to provide a better understanding of the malaria prevalence and disease burden due to <jats:italic>P. malariae<\/jats:italic> and <jats:italic>P. ovale<\/jats:italic> spp.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the Joanna Briggs Institute prevalence study assessment tool were used to select and evaluate the studies, respectively. Six databases: PubMed, WHOLIS, Wiley Library, ScienceDirect, Web of Science and Google Scholar were used to screen articles published during the period January 2000\u2013December 2020. The pooled prevalence estimates for <jats:italic>P. malariae<\/jats:italic> and <jats:italic>P. ovale<\/jats:italic> spp. were analysed using a random-effects model and the possible sources of heterogeneity were evaluated through subgroup analysis and meta-regression.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Out of the 3297 studies screened, only 113 studies were included; among which 51.33% were from the African Region. The <jats:italic>P. malariae<\/jats:italic> and <jats:italic>P. ovale<\/jats:italic> spp. pooled prevalence were 2.01% (95% CI 1.31\u20132.85%) and 0.77% (95% CI 0.50\u20131.10%) respectively, with the highest prevalence in the African Region. <jats:italic>P. malariae<\/jats:italic> was equally distributed among adults (2.13%), children (2.90%) and pregnant women (2.77%) (<jats:italic>p<\/jats:italic>\u2009=\u20090.862), whereas <jats:italic>P. ovale<\/jats:italic> spp. was more prevalent in pregnant women (2.90%) than in children\u2009\u2264\u200915\u00a0years (0.97%) and in patients\u2009&gt;\u200915\u00a0years old (0.39%) (<jats:italic>p<\/jats:italic>\u2009=\u20090.021). In this review, data analysis revealed that <jats:italic>P. malariae<\/jats:italic> and <jats:italic>P. ovale<\/jats:italic> spp. have decreased in the last 20\u00a0years, but not significantly, and these species were more commonly present with other <jats:italic>Plasmodium<\/jats:italic> species as co-infections. No difference in prevalence between symptomatic and asymptomatic patients was observed for either <jats:italic>P. malariae<\/jats:italic> or <jats:italic>P. ovale<\/jats:italic> spp.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Our analysis suggests that knowledge of the worldwide burden of <jats:italic>P. malariae<\/jats:italic> and <jats:italic>P. ovale<\/jats:italic> spp. is very important for malaria elimination programmes and a particular focus towards improved tools for monitoring transmission for these non-falciparum species should be stressed upon\u00a0to deal with increased infections in the future.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical Abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1186\/s13071-021-04797-0","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T09:03:16Z","timestamp":1622710996000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["Global trend of Plasmodium malariae and Plasmodium ovale spp. malaria infections in the last two decades (2000\u20132020): a systematic review and meta-analysis"],"prefix":"10.1186","volume":"14","author":[{"given":"Joseph","family":"Hawadak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigue Roman","family":"Dongang Nana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0113-7394","authenticated-orcid":false,"given":"Vineeta","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,3]]},"reference":[{"key":"4797_CR1","volume-title":"World malaria report 2020","author":"WHO","year":"2020","unstructured":"WHO. 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