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Given the absence of a therapeutic intervention, the study was not prospectively registered in an external trial registry. However, as participants were randomized to the diagnostic strategies, the study qualifies as an interventional trial following current recommendations from the International Committee of Medical Journal Editors. The trial was therefore retrospectively registered on\n                      \n                      (NCT07051213). The study was performed in accordance with the Declaration of Helsinki. Written informed consent was obtained from all participants or their legal representatives.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Consent for publication was obtained from all participants or their legal representatives.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Illumina Inc. 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