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OD had a consultancy relationship and\/or has received research funding from Actelion, AnaMar, Bayer, Boehringer Ingelheim, ChemomAb, espeRare foundation, Genentech\/Roche, GSK, Inventiva, Italfarmaco, Lilly, medac, MedImmune, Mitsubishi Tanabe Pharma, Novartis, Pfizer, Sanofi, Sinoxa and UCB in the area of potential treatments for scleroderma and its complications. In addition, OD has a patent mir-29 licensed for the treatment of systemic sclerosis. The real or perceived potential conflicts listed above are accurately stated.BM had grant\/research support from AbbVie, Protagen, Novartis, congress support from Pfizer, Roche and Actelion. In addition, BM has a patent mir-29 licensed for the treatment of systemic sclerosis. The real or perceived potential conflicts listed above are accurately stated.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"183"}}