{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T22:26:18Z","timestamp":1776464778559,"version":"3.51.2"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2015-03006"],"award-info":[{"award-number":["2015-03006"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["K2014-52X-14045-14"],"award-info":[{"award-number":["K2014-52X-14045-14"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007949","name":"Reumatikerf\u00f6rbundet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007949","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007857","name":"Stiftelsen Konung Gustaf V:s 80-\u00e5rsfond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007857","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004348","name":"Stockholms L\u00e4ns Landsting","doi-asserted-by":"publisher","award":["ALF"],"award-info":[{"award-number":["ALF"]}],"id":[{"id":"10.13039\/501100004348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arthritis Res Ther"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s13075-018-1688-7","type":"journal-article","created":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T15:08:23Z","timestamp":1535555303000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5317-0327","authenticated-orcid":false,"given":"Miranda","family":"Houtman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Ekholm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Espen","family":"Hesselberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karine","family":"Chemin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivianne","family":"Malmstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann M.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid E.","family":"Lundberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonid","family":"Padyukov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,8,29]]},"reference":[{"key":"1688_CR1","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/S0140-6736(03)14368-1","volume":"362","author":"MC Dalakas","year":"2003","unstructured":"Dalakas MC, Hohlfeld R. Polymyositis and dermatomyositis. Lancet. 2003;362:971\u201382.","journal-title":"Lancet"},{"key":"1688_CR2","doi-asserted-by":"publisher","first-page":"1558\u201366","DOI":"10.1136\/annrheumdis-2015-208119","volume":"75","author":"S Rothwell","year":"2016","unstructured":"Rothwell S, Cooper RG, Lundberg IE, Miller FW, Gregersen PK, Bowes J, et al. Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Ann Rheum Dis. 2016;75:1558\u201366.","journal-title":"Ann Rheum Dis"},{"key":"1688_CR3","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/0198-8859(81)90055-0","volume":"3","author":"TJ Hirsch","year":"1981","unstructured":"Hirsch TJ, Enlow RW, Bias WB, Arnett FC. HLA-D related (DR) antigens in various kinds of myositis. Hum Immunol. 1981;3:181\u20136.","journal-title":"Hum Immunol"},{"key":"1688_CR4","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1097\/01.md.0000189818.63141.8c","volume":"84","author":"TP O'Hanlon","year":"2005","unstructured":"O'Hanlon TP, Carrick DM, Arnett FC, Reveille JD, Carrington M, Gao X, et al. Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in Caucasians. Medicine. 2005;84:338\u201349.","journal-title":"Medicine"},{"key":"1688_CR5","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/s11926-013-0335-1","volume":"15","author":"A Ghirardello","year":"2013","unstructured":"Ghirardello A, Bassi N, Palma L, Borella E, Domeneghetti M, Punzi L, et al. Autoantibodies in polymyositis and dermatomyositis. Curr Rheumatol Rep. 2013;15:335.","journal-title":"Curr Rheumatol Rep"},{"key":"1688_CR6","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1002\/ana.410160206","volume":"16","author":"K Arahata","year":"1984","unstructured":"Arahata K, Engel AG. Monoclonal antibody analysis of mononuclear cells in myopathies. I: quantitation of subsets according to diagnosis and sites of accumulation and demonstration and counts of muscle fibers invaded by T cells. Ann Neurol. 1984;16:193\u2013208.","journal-title":"Ann Neurol"},{"key":"1688_CR7","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1002\/ana.410160207","volume":"16","author":"AG Engel","year":"1984","unstructured":"Engel AG, Arahata K. Monoclonal antibody analysis of mononuclear cells in myopathies. II: phenotypes of autoinvasive cells in polymyositis and inclusion body myositis. Ann Neurol. 1984;16:209\u201315.","journal-title":"Ann Neurol"},{"key":"1688_CR8","doi-asserted-by":"publisher","first-page":"2905","DOI":"10.1172\/JCI118749","volume":"97","author":"N Goebels","year":"1996","unstructured":"Goebels N, Michaelis D, Engelhardt M, Huber S, Bender A, Pongratz D, et al. Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis. J Clin Invest. 1996;97:2905\u201310.","journal-title":"J Clin Invest"},{"key":"1688_CR9","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/0960-8966(94)90022-1","volume":"4","author":"S Orimo","year":"1994","unstructured":"Orimo S, Koga R, Goto K, Nakamura K, Arai M, Tamaki M, et al. Immunohistochemical analysis of perforin and granzyme a in inflammatory myopathies. Neuromuscul Disord. 1994;4:219\u201326.","journal-title":"Neuromuscul Disord"},{"key":"1688_CR10","doi-asserted-by":"publisher","first-page":"4792\u20139","DOI":"10.4049\/jimmunol.0803688","volume":"183","author":"AER Fasth","year":"2009","unstructured":"Fasth AER, Dastmalchi M, Rahbar A, Salomonsson S, Pandya JM, Lindroos E, et al. T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells. J Immunol. 2009;183:4792\u20139.","journal-title":"J Immunol"},{"key":"1688_CR11","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.1002\/art.39650","volume":"68","author":"JM Pandya","year":"2016","unstructured":"Pandya JM, Venalis P, Al-Khalili L, Hossain MS, Stache V, Lundberg IE, et al. CD4+ and CD8+ CD28null T cells are cytotoxic to autologous muscle cells in patients with polymyositis. Arthritis Rheumatol. 2016;68:2016\u201326.","journal-title":"Arthritis Rheumatol"},{"key":"1688_CR12","doi-asserted-by":"publisher","first-page":"3521\u20139","DOI":"10.4049\/jimmunol.167.6.3521","volume":"167","author":"O Benveniste","year":"2001","unstructured":"Benveniste O, Ch\u00e9rin P, Maisonobe T, Merat R, Chosidow O, Mouthon L, et al. Severe perturbations of the blood T cell repertoire in polymyositis, but not dermatomyositis patients. J Immunol. 2001;167:3521\u20139.","journal-title":"J Immunol"},{"key":"1688_CR13","doi-asserted-by":"publisher","first-page":"1955\u201364","DOI":"10.1136\/annrheumdis-2017-211468","volume":"76","author":"IE Lundberg","year":"2017","unstructured":"Lundberg IE, Tj\u00e4rnlund A, Bottai M, Werth VP, Pilkington C, de Visser M, et al. 2017 European League Against Rheumatism\/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups. Ann Rheum Dis. 2017;76:1955\u201364.","journal-title":"Ann Rheum Dis"},{"key":"1688_CR14","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1056\/NEJM197502132920706","volume":"292","author":"A Bohan","year":"1975","unstructured":"Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med. 1975;292:344\u20137.","journal-title":"N Engl J Med"},{"key":"1688_CR15","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1056\/NEJM197502202920807","volume":"292","author":"A Bohan","year":"1975","unstructured":"Bohan A, Peter JB. Polymyositis and dermatomyositis (second of two parts). N Engl J Med. 1975;292:403\u20137.","journal-title":"N Engl J Med"},{"key":"1688_CR16","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/j.1399-0039.1992.tb01940.x","volume":"39","author":"O Olerup","year":"1992","unstructured":"Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens. 1992;39:225\u201335.","journal-title":"Tissue Antigens"},{"key":"1688_CR17","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","volume":"29","author":"A Dobin","year":"2013","unstructured":"Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics. 2013;29:15\u201321.","journal-title":"Bioinformatics"},{"key":"1688_CR18","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1186\/s13059-017-1349-1","volume":"18","author":"D Aran","year":"2017","unstructured":"Aran D, Hu Z, Butte AJ. xCell: digitally portraying the tissue cellular heterogeneity landscape. Genome Biol. 2017;18:220.","journal-title":"Genome Biol"},{"key":"1688_CR19","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/nmeth.4197","volume":"14","author":"R Patro","year":"2017","unstructured":"Patro R, Duggal G, Love MI, Irizarry RA, Kingsford C. Salmon: fast and bias-aware quantification of transcript expression using dual-phase inference. Nat Methods. 2017;14:417\u20139.","journal-title":"Nat Methods"},{"key":"1688_CR20","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15:550.","journal-title":"Genome Biol"},{"key":"1688_CR21","doi-asserted-by":"publisher","first-page":"1867","DOI":"10.1093\/rheumatology\/keq151","volume":"49","author":"P Szodoray","year":"2010","unstructured":"Szodoray P, Alex P, Knowlton N, Centola M, Dozmorov I, Csipo I, et al. Idiopathic inflammatory myopathies, signified by distinctive peripheral cytokines, chemokines and the TNF family members B-cell activating factor and a proliferation inducing ligand. Rheumatology (Oxford). 2010;49:1867\u201377.","journal-title":"Rheumatology (Oxford)"},{"key":"1688_CR22","doi-asserted-by":"publisher","first-page":"1170\u201382","DOI":"10.1212\/WNL.59.8.1170","volume":"59","author":"SA Greenberg","year":"2002","unstructured":"Greenberg SA, Sanoudou D, Haslett JN, Kohane IS, Kunkel LM, Beggs AH, et al. Molecular profiles of inflammatory myopathies. Neurology. 2002;59:1170\u201382.","journal-title":"Neurology"},{"key":"1688_CR23","doi-asserted-by":"publisher","first-page":"4612","DOI":"10.1172\/JCI81031","volume":"125","author":"I Albrecht","year":"2015","unstructured":"Albrecht I, Wick C, Hallgren \u00c5, Tj\u00e4rnlund A, Nagaraju K, Andrade F, et al. Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies. J Clin Invest. 2015;125:4612\u201324.","journal-title":"J Clin Invest"},{"key":"1688_CR24","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1002\/art.22790","volume":"56","author":"M Levine Stuart","year":"2007","unstructured":"Levine Stuart M, Raben N, Xie D, Askin Frederic B, Tuder R, Mullins M, et al. Novel conformation of histidyl\u2013transfer RNA synthetase in the lung. Arthritis Rheum. 2007;56:2729\u201339.","journal-title":"Arthritis Rheum"},{"key":"1688_CR25","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1002\/art.22293","volume":"56","author":"P Englund","year":"2007","unstructured":"Englund P, Wahlstr\u00f6m J, Fathi M, Rasmussen E, Grunewald J, Tornling G, et al. Restricted T cell receptor BV gene usage in the lungs and muscles of patients with idiopathic inflammatory myopathies. Arthritis Rheum. 2007;56:372\u201383.","journal-title":"Arthritis Rheum"},{"key":"1688_CR26","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1097\/00005072-199705000-00003","volume":"56","author":"P Confalonieri","year":"1997","unstructured":"Confalonieri P, Bernasconi P, Cornelio F, Mantegazza R. Transforming growth factor-\u03b21 in polymyositis and dermatomyositis correlates with fibrosis but not with mononuclear cell infiltrate. J Neuropathol Exp Neurol. 1997;56:479\u201384.","journal-title":"J Neuropathol Exp Neurol"},{"key":"1688_CR27","doi-asserted-by":"publisher","first-page":"2041\u201356","DOI":"10.1084\/jem.20150186","volume":"212","author":"CX Dominguez","year":"2015","unstructured":"Dominguez CX, Amezquita RA, Guan T, Marshall HD, Joshi NS, Kleinstein SH, et al. The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection. J Exp Med. 2015;212:2041\u201356.","journal-title":"J Exp Med"},{"key":"1688_CR28","doi-asserted-by":"publisher","first-page":"2027\u201339","DOI":"10.1084\/jem.20150194","volume":"212","author":"KD Omilusik","year":"2015","unstructured":"Omilusik KD, Best JA, Yu B, Goossens S, Weidemann A, Nguyen JV, et al. Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection. J Exp Med. 2015;212:2027\u201339.","journal-title":"J Exp Med"},{"key":"1688_CR29","doi-asserted-by":"publisher","first-page":"20489","DOI":"10.1074\/jbc.274.29.20489","volume":"274","author":"K Verschueren","year":"1999","unstructured":"Verschueren K, Remacle JE, Collart C, Kraft H, Baker BS, Tylzanowski P, et al. SIP1, a novel zinc finger\/homeodomain repressor, interacts with Smad proteins and binds to 5\u2032-CACCT sequences in candidate target genes. J Biol Chem. 1999;274:20489\u201398.","journal-title":"J Biol Chem"},{"key":"1688_CR30","doi-asserted-by":"publisher","first-page":"15168","DOI":"10.1021\/bi062188q","volume":"45","author":"J Li","year":"2006","unstructured":"Li J, Mahajan A, Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry. 2006;45:15168\u201378.","journal-title":"Biochemistry"},{"key":"1688_CR31","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1038\/ng.582","volume":"42","author":"EA Stahl","year":"2010","unstructured":"Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet. 2010;42:508\u201314.","journal-title":"Nat Genet"},{"key":"1688_CR32","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1038\/nature12873","volume":"506","author":"Y Okada","year":"2014","unstructured":"Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, et al. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 2014;506:376\u201381.","journal-title":"Nature"},{"key":"1688_CR33","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1038\/ng.2462","volume":"44","author":"S Eyre","year":"2012","unstructured":"Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, et al. High density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012;44:1336\u201340.","journal-title":"Nat Genet"},{"key":"1688_CR34","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1038\/nature11582","volume":"491","author":"L Jostins","year":"2012","unstructured":"Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012;491:119\u201324.","journal-title":"Nature"},{"key":"1688_CR35","first-page":"253\u20137","volume":"13","author":"I Alloza","year":"2011","unstructured":"Alloza I, Otaegui D, de Lapuente AL, Antig\u00fcedad A, Varad\u00e9 J, N\u00fa\u00f1ez C, et al. ANKRD55 and DHCR7 are novel multiple sclerosis risk loci. Genes Immun. 2011;13:253\u20137.","journal-title":"Genes Immun"},{"key":"1688_CR36","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/0361-9230(95)00040-2","volume":"37","author":"DB Zimmer","year":"1995","unstructured":"Zimmer DB, Cornwall EH, Landar A, Song W. The S100 protein family: history, function, and expression. Brain Res Bull. 1995;37:417\u201329.","journal-title":"Brain Res Bull"},{"key":"1688_CR37","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1016\/j.bbi.2011.03.015","volume":"25","author":"J Steiner","year":"2011","unstructured":"Steiner J, Marquardt N, Pauls I, Schiltz K, Rahmoune H, Bahn S, et al. Human CD8+ T cells and NK cells express and secrete S100B upon stimulation. Brain Behav Immun. 2011;25:1233\u201341.","journal-title":"Brain Behav Immun"},{"key":"1688_CR38","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1038\/gene.2015.28","volume":"16","author":"FW Miller","year":"2015","unstructured":"Miller FW, Chen W, O\u2019Hanlon TP, Cooper RG, Vencovsky J, Rider LG, et al. Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. Genes Immun. 2015;16:470\u201380.","journal-title":"Genes Immun"},{"key":"1688_CR39","doi-asserted-by":"publisher","first-page":"325","DOI":"10.3389\/fimmu.2017.00325","volume":"8","author":"AE Oja","year":"2017","unstructured":"Oja AE, Vieira Braga FA, Remmerswaal EBM, Kragten NAM, Hertoghs KML, Zuo J, et al. The transcription factor Hobit identifies human cytotoxic CD4+ T cells. Front Immunol. 2017;8:325.","journal-title":"Front Immunol"},{"key":"1688_CR40","doi-asserted-by":"publisher","first-page":"459\u201363","DOI":"10.1126\/science.aad2035","volume":"352","author":"LK Mackay","year":"2016","unstructured":"Mackay LK, Minnich M, Kragten NAM, Liao Y, Nota B, Seillet C, et al. Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science. 2016;352:459\u201363.","journal-title":"Science"},{"key":"1688_CR41","doi-asserted-by":"publisher","first-page":"864\u201371","DOI":"10.1038\/ni.2393","volume":"13","author":"KPJM van Gisbergen","year":"2012","unstructured":"van Gisbergen KPJM, Kragten NAM, Hertoghs KML, Wensveen FM, Jonjic S, Hamann J, et al. Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation. Nat Immunol. 2012;13:864\u201371.","journal-title":"Nat Immunol"},{"key":"1688_CR42","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/j.0105-2896.2005.00310.x","volume":"207","author":"C Hsing L","year":"2005","unstructured":"Hsing L C, Rudensky AY. The lysosomal cysteine proteases in MHC class II antigen presentation. Immunol Rev. 2005;207:229\u201341.","journal-title":"Immunol Rev"},{"key":"1688_CR43","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.exphem.2008.10.011","volume":"37","author":"C Stoeckle","year":"2009","unstructured":"Stoeckle C, Gouttefangeas C, Hammer M, Weber E, Melms A, Tolosa E. Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs. Exp Hematol. 2009;37:266\u201375.","journal-title":"Exp Hematol"},{"key":"1688_CR44","doi-asserted-by":"publisher","first-page":"3784","DOI":"10.1002\/art.22928","volume":"56","author":"RJ Walsh","year":"2007","unstructured":"Walsh RJ, Kong SW, Yao Y, Jallal B, Kiener PA, Pinkus JL, et al. Type I interferon\u2013inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis. Arthritis Rheum. 2007;56:3784\u201392.","journal-title":"Arthritis Rheum"},{"key":"1688_CR45","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1186\/s13075-015-0564-y","volume":"17","author":"TD de Jong","year":"2015","unstructured":"de Jong TD, Vosslamber S, Blits M, Wolbink G, Nurmohamed MT, van der Laken CJ, et al. Effect of prednisone on type I interferon signature in rheumatoid arthritis: consequences for response prediction to rituximab. Arthritis Res Ther. 2015;17:78.","journal-title":"Arthritis Res Ther"},{"key":"1688_CR46","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1002\/acr.21728","volume":"64","author":"H Cao","year":"2012","unstructured":"Cao H, Pan M, Kang Y, Xia Q, Li X, Zhao X, et al. Clinical manifestations of dermatomyositis and clinically amyopathic dermatomyositis patients with positive expression of anti\u2013melanoma differentiation\u2013associated gene 5 antibody. Arthritis Care Res (Hoboken). 2012;64:1602\u201310.","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"1688_CR47","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1002\/art.33379","volume":"64","author":"E Trallero-Aragu\u00e1s","year":"2012","unstructured":"Trallero-Aragu\u00e1s E, Rodrigo-Pend\u00e1s Jose \u00c1, Selva-O'Callaghan A, Mart\u00ednez-G\u00f3mez X, Bosch X, Labrador-Horrillo M, et al. Usefulness of anti-p155 autoantibody for diagnosing cancer-associated dermatomyositis: a systematic review and meta-analysis. Arthritis Rheum. 2012;64:523\u201332.","journal-title":"Arthritis Rheum"},{"key":"1688_CR48","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1136\/ard.2003.006122","volume":"63","author":"M Fathi","year":"2004","unstructured":"Fathi M, Dastmalchi M, Rasmussen E, Lundberg I, Tornling G. Interstitial lung disease, a common manifestation of newly diagnosed polymyositis and dermatomyositis. Ann Rheum Dis. 2004;63:297\u2013301.","journal-title":"Ann Rheum Dis"}],"container-title":["Arthritis Research & Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13075-018-1688-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13075-018-1688-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13075-018-1688-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T09:41:09Z","timestamp":1569231669000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/s13075-018-1688-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,29]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["1688"],"URL":"https:\/\/doi.org\/10.1186\/s13075-018-1688-7","relation":{},"ISSN":["1478-6362"],"issn-type":[{"value":"1478-6362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,29]]},"assertion":[{"value":"26 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethics approval was provided by permission from the Stockholm Regional Ethics Board and by written consent from the patients.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"188"}}