{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:11:13Z","timestamp":1790032273106,"version":"4.0.1"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,9,20]],"date-time":"2020-09-20T00:00:00Z","timestamp":1600560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,9,20]],"date-time":"2020-09-20T00:00:00Z","timestamp":1600560000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770072"],"award-info":[{"award-number":["81770072"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["ZYJC18021"],"award-info":[{"award-number":["ZYJC18021"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arthritis Res Ther"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the associations between aspartate transaminase\/alanine transaminase ratio (DRR) and mortality in patients with polymyositis\/dermatomyositis-associated interstitial lung disease (PM\/DM-ILD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>This was a retrospective cohort study, which included 522 patients with PM\/DM-ILD whose DRR on admission were tested at West China Hospital of Sichuan University during the period from January 1, 2008, to December 31, 2018. Cox regression models were used to estimate hazard ratios for mortality in four predefined DRR strata (\u2264\u20090.91, 0.91\u20131.26, 1.26\u20131.73, and &gt;\u20091.73), after adjusting for age, sex, DRR stratum, diagnosis, overlap syndrome, hemoglobin, platelet count, white blood cell count, the percentage of neutrophils, neutrophil\/lymphocyte ratio, albumin, creatine kinase, uric acid\/creatinine ratio, triglycerides, or low-density lipoprotein.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Higher DRR (&gt;\u20091.73) was an independent predictor of 1-year mortality in multivariate Cox regression analysis (hazard ratio 3.423, 95% CI 1.481\u20137.911,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.004). Patients with higher DRR more often required the use of mechanical ventilation and readmission for acute exacerbation of PM\/DM-ILD at 1-year follow-up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher DRR on admission for PM\/DM-ILD patients are associated with increased mortality, risk of mechanical ventilation, and hospitalization in 1-year follow-up. This low-cost, easy-to-obtain, rapidly measured biomarker may be useful in the identification of high-risk PM\/DM-ILD patients that could benefit from intensive management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13075-020-02286-w","type":"journal-article","created":{"date-parts":[[2020,9,19]],"date-time":"2020-09-19T19:06:00Z","timestamp":1600542360000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["AST\/ALT ratio as a predictor of mortality and exacerbations of PM\/DM-ILD in 1\u2009year\u2014a retrospective cohort study with 522 cases"],"prefix":"10.1186","volume":"22","author":[{"given":"Renjiao","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoju","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9267-3437","authenticated-orcid":false,"given":"Fengming","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,20]]},"reference":[{"issue":"9388","key":"2286_CR1","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0140-6736(03)14368-1","volume":"362","author":"MC Dalakas","year":"2003","unstructured":"Dalakas MC, Hohlfeld R. Polymyositis and dermatomyositis. Lancet. 2003;362(9388):971\u201382.","journal-title":"Lancet"},{"key":"2286_CR2","doi-asserted-by":"crossref","first-page":"h6819","DOI":"10.1136\/bmj.h6819","volume":"352","author":"SC Mathai","year":"2016","unstructured":"Mathai SC, Danoff SK. Management of interstitial lung disease associated with connective tissue disease. BMJ. 2016;352:h6819.","journal-title":"BMJ"},{"issue":"6","key":"2286_CR3","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1007\/s10067-009-1110-6","volume":"28","author":"IJ Chen","year":"2009","unstructured":"Chen IJ, Jan Wu YJ, Lin CW, Fan KW, Luo SF, Ho HH, et al. Interstitial lung disease in polymyositis and dermatomyositis. Clin Rheumatol. 2009;28(6):639\u201346.","journal-title":"Clin Rheumatol"},{"issue":"2","key":"2286_CR4","first-page":"260","volume":"35","author":"S Hayashi","year":"2008","unstructured":"Hayashi S, Tanaka M, Kobayashi H, Nakazono T, Satoh T, Fukuno Y, et al. High-resolution computed tomography characterization of interstitial lung diseases in polymyositis\/dermatomyositis. J Rheumatol. 2008;35(2):260\u20139.","journal-title":"J Rheumatol"},{"issue":"3","key":"2286_CR5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/art.1780280303","volume":"28","author":"J Benbassat","year":"1985","unstructured":"Benbassat J, Gefel D, Larholt K, Sukenik S, Morgenstern V, Zlotnick A. Prognostic factors in polymyositis\/dermatomyositis. A computer-assisted analysis of ninety-two cases. Arthritis Rheum. 1985;28(3):249\u201355.","journal-title":"Arthritis Rheum"},{"issue":"5","key":"2286_CR6","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1002\/art.23571","volume":"59","author":"M Fathi","year":"2008","unstructured":"Fathi M, Vikgren J, Boijsen M, Tylen U, Jorfeldt L, Tornling G, et al. Interstitial lung disease in polymyositis and dermatomyositis: longitudinal evaluation by pulmonary function and radiology. Arthritis Rheum. 2008;59(5):677\u201385.","journal-title":"Arthritis Rheum"},{"issue":"1","key":"2286_CR7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13075-017-1506-7","volume":"20","author":"Y Sugiyama","year":"2018","unstructured":"Sugiyama Y, Yoshimi R, Tamura M, Takeno M, Kunishita Y, Kishimoto D, et al. The predictive prognostic factors for polymyositis\/dermatomyositis-associated interstitial lung disease. Arthritis Res Ther. 2018;20(1):7.","journal-title":"Arthritis Res Ther"},{"issue":"10","key":"2286_CR8","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.autrev.2014.08.023","volume":"13","author":"MG Danieli","year":"2014","unstructured":"Danieli MG, Gambini S, Pettinari L, Logullo F, Veronesi G, Gabrielli A. Impact of treatment on survival in polymyositis and dermatomyositis. A single-centre long-term follow-up study. Autoimmun Rev. 2014;13(10):1048\u201354.","journal-title":"Autoimmun Rev"},{"issue":"1","key":"2286_CR9","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0009-8981(57)90027-X","volume":"2","author":"F De Ritis","year":"1957","unstructured":"De Ritis F, Coltorti M, Giusti G. An enzymic test for the diagnosis of viral hepatitis; the transaminase serum activities. Clin Chim Acta. 1957;2(1):70\u20134.","journal-title":"Clin Chim Acta"},{"issue":"3","key":"2286_CR10","first-page":"117","volume":"34","author":"M Botros","year":"2013","unstructured":"Botros M, Sikaris KA. The de ritis ratio: the test of time. Clin Biochem Rev. 2013;34(3):117\u201330.","journal-title":"Clin Biochem Rev"},{"issue":"1","key":"2286_CR11","first-page":"40","volume":"8","author":"S Majhi","year":"2006","unstructured":"Majhi S, Baral N, Lamsal M, Mehta KD. De Ritis ratio as diagnostic marker of alcoholic liver disease. Nepal Med Coll J. 2006;8(1):40\u20132.","journal-title":"Nepal Med Coll J"},{"issue":"1","key":"2286_CR12","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s12291-013-0310-7","volume":"29","author":"PP Torkadi","year":"2014","unstructured":"Torkadi PP, Apte IC, Bhute AK. Biochemical evaluation of patients of alcoholic liver disease and non-alcoholic liver disease. Indian J Clin Biochem. 2014;29(1):79\u201383.","journal-title":"Indian J Clin Biochem"},{"issue":"11","key":"2286_CR13","doi-asserted-by":"crossref","first-page":"e13411","DOI":"10.1111\/ctr.13411","volume":"32","author":"F Darstein","year":"2018","unstructured":"Darstein F, Hauser F, Straub BK, Wenzel JJ, Conradi R, Mittler J, et al. Hepatitis E virus genotype 3 is a common finding in liver-transplanted patients undergoing liver biopsy for elevated liver enzymes with a low De Ritis ratio and suspected acute rejection: a real-world cohort. Clin Transpl. 2018;32(11):e13411.","journal-title":"Clin Transpl"},{"issue":"24","key":"2286_CR14","doi-asserted-by":"crossref","first-page":"e3843","DOI":"10.1097\/MD.0000000000003843","volume":"95","author":"P Rief","year":"2016","unstructured":"Rief P, Pichler M, Raggam R, Hafner F, Gerger A, Eller P, et al. The AST\/ALT (De-Ritis) ratio: a novel marker for critical limb ischemia in peripheral arterial occlusive disease patients. Medicine (Baltimore). 2016;95(24):e3843.","journal-title":"Medicine (Baltimore)"},{"key":"2286_CR15","doi-asserted-by":"crossref","unstructured":"Steininger M, Winter MP, Reiberger T, Koller L, El-Hamid F, Forster S, et al. De-Ritis ratio improves long-term risk prediction after acute myocardial infarction. J Clin Med. 2018:7(12). PMID 30477196.","DOI":"10.3390\/jcm7120474"},{"key":"2286_CR16","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.2147\/NDT.S139316","volume":"13","author":"F Gao","year":"2017","unstructured":"Gao F, Chen C, Lu J, Zheng J, Ma XC, Yuan XY, et al. De Ritis ratio (AST\/ALT) as an independent predictor of poor outcome in patients with acute ischemic stroke. Neuropsychiatr Dis Treat. 2017;13:1551\u20137.","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"1","key":"2286_CR17","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.juro.2015.01.083","volume":"194","author":"A Bezan","year":"2015","unstructured":"Bezan A, Mrsic E, Krieger D, Stojakovic T, Pummer K, Zigeuner R, et al. The preoperative AST\/ALT (De Ritis) ratio represents a poor prognostic factor in a cohort of patients with nonmetastatic renal cell carcinoma. J Urol. 2015;194(1):30\u20135.","journal-title":"J Urol"},{"issue":"2","key":"2286_CR18","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/bju.13545","volume":"119","author":"H Lee","year":"2017","unstructured":"Lee H, Lee SE, Byun SS, Kim HH, Kwak C, Hong SK. De Ritis ratio (aspartate transaminase\/alanine transaminase ratio) as a significant prognostic factor after surgical treatment in patients with clear-cell localized renal cell carcinoma: a propensity score-matched study. BJU Int. 2017;119(2):261\u20137.","journal-title":"BJU Int"},{"issue":"3","key":"2286_CR19","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1164\/ajrccm.165.3.2107134","volume":"165","author":"H Ohnishi","year":"2002","unstructured":"Ohnishi H, Yokoyama A, Kondo K, Hamada H, Abe M, Nishimura K, et al. Comparative study of KL-6, surfactant protein-A, surfactant protein-D, and monocyte chemoattractant protein-1 as serum markers for interstitial lung diseases. Am J Respir Crit Care Med. 2002;165(3):378\u201381.","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"2286_CR20","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1378\/chest.100.4.1182-b","volume":"100","author":"RG McFadden","year":"1991","unstructured":"McFadden RG, Oliphant LD. Serum lactate dehydrogenase in interstitial lung disease. Chest. 1991;100(4):1182.","journal-title":"Chest"},{"issue":"7","key":"2286_CR21","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1056\/NEJM197502132920706","volume":"292","author":"A Bohan","year":"1975","unstructured":"Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med. 1975;292(7):344\u20137.","journal-title":"N Engl J Med"},{"issue":"4","key":"2286_CR22","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1067\/mjd.2002.120621","volume":"46","author":"RD Sontheimer","year":"2002","unstructured":"Sontheimer RD. Would a new name hasten the acceptance of amyopathic dermatomyositis (dermatomyositis sine myositis) as a distinctive subset within the idiopathic inflammatory dermatomyopathies spectrum of clinical illness? J Am Acad Dermatol. 2002;46(4):626\u201336.","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"2286_CR23","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1007\/s10067-014-2837-2","volume":"34","author":"YS An","year":"2015","unstructured":"An YS, Suh CH, Jung JY, Kim HA. Role of bone scan in the assessment of polymyositis\/dermatomyositis. Clin Rheumatol. 2015;34(4):699\u2013706.","journal-title":"Clin Rheumatol"},{"issue":"7","key":"2286_CR24","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1164\/rccm.200703-463PP","volume":"176","author":"HR Collard","year":"2007","unstructured":"Collard HR, Moore BB, Flaherty KR, Brown KK, Kaner RJ, King TE Jr, et al. Acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2007;176(7):636\u201343.","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"2286_CR25","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.semarthrit.2017.10.010","volume":"47","author":"A Schiffenbauer","year":"2018","unstructured":"Schiffenbauer A, Garg M, Castro C, Pokrovnichka A, Joe G, Shrader J, et al. A randomized, double-blind, placebo-controlled trial of infliximab in refractory polymyositis and dermatomyositis. Semin Arthritis Rheum. 2018;47(6):858\u201364.","journal-title":"Semin Arthritis Rheum"},{"issue":"8","key":"2286_CR26","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1093\/rheumatology\/kex070","volume":"56","author":"Z Zhong","year":"2017","unstructured":"Zhong Z, Lin F, Yang J, Zhang F, Zeng X, You X. Pregnancy in polymyositis or dermatomyositis: retrospective results from a tertiary centre in China. Rheumatology (Oxford). 2017;56(8):1272\u20135.","journal-title":"Rheumatology (Oxford)"},{"issue":"12","key":"2286_CR27","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1093\/clinchem\/46.12.2027","volume":"46","author":"DR Dufour","year":"2000","unstructured":"Dufour DR, Lott JA, Nolte FS, Gretch DR, Koff RS, Seeff LB. Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests. Clin Chem. 2000;46(12):2027\u201349.","journal-title":"Clin Chem"},{"issue":"1","key":"2286_CR28","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.berh.2016.04.007","volume":"30","author":"J Tieu","year":"2016","unstructured":"Tieu J, Lundberg IE, Limaye V. Idiopathic inflammatory myositis. Best Pract Res Clin Rheumatol. 2016;30(1):149\u201368.","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"4","key":"2286_CR29","doi-asserted-by":"crossref","first-page":"731","DOI":"10.5811\/westjem.2018.3.37076","volume":"19","author":"JB Radke","year":"2018","unstructured":"Radke JB, Algren DA, Chenoweth JA, Owen KP, Ford JB, Albertson TE, et al. Transaminase and creatine kinase ratios for differentiating delayed acetaminophen overdose from rhabdomyolysis. West J Emerg Med. 2018;19(4):731\u20136.","journal-title":"West J Emerg Med"},{"issue":"5","key":"2286_CR30","first-page":"339","volume":"78","author":"CD Russell","year":"2019","unstructured":"Russell CD, Parajuli A, Gale HJ, Bulteel NS, Schuetz P, de Jager CPC, et al. The utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: a systematic review and meta-analysis. J Inf Secur. 2019;78(5):339\u201348.","journal-title":"J Inf Secur"},{"key":"2286_CR31","doi-asserted-by":"crossref","unstructured":"Wollin L, Distler JHW, Redente EF, Riches DWH, Stowasser S, Schlenker-Herceg R et al: Potential of nintedanib in treatment of progressive fibrosing interstitial lung diseases. Eur Respir J 2019, 54(3). PMID 31285305.","DOI":"10.1183\/13993003.00161-2019"},{"issue":"3","key":"2286_CR32","first-page":"148","volume":"32","author":"T Schroder","year":"2013","unstructured":"Schroder T, Fuchss J, Schneider I, Stoltenburg-Didinger G, Hanisch F. Eosinophils in hereditary and inflammatory myopathies. Acta Myol. 2013;32(3):148\u201353.","journal-title":"Acta Myol"},{"issue":"1","key":"2286_CR33","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1378\/chest.108.1.48","volume":"108","author":"K Fujimoto","year":"1995","unstructured":"Fujimoto K, Kubo K, Yamaguchi S, Honda T, Matsuzawa Y. Eosinophil activation in patients with pulmonary fibrosis. Chest. 1995;108(1):48\u201354.","journal-title":"Chest"},{"issue":"4","key":"2286_CR34","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.pop.2016.07.010","volume":"43","author":"A Kovalszki","year":"2016","unstructured":"Kovalszki A, Weller PF. Eosinophilia. Prim Care. 2016;43(4):607\u201317.","journal-title":"Prim Care"},{"issue":"1","key":"2286_CR35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mcna.2019.08.005","volume":"104","author":"FL Kuang","year":"2020","unstructured":"Kuang FL. Approach to patients with eosinophilia. Med Clin North Am. 2020;104(1):1\u201314.","journal-title":"Med Clin North Am"},{"issue":"12","key":"2286_CR36","first-page":"e3677","volume":"10","author":"H Sheikh","year":"2018","unstructured":"Sheikh H, Siddiqui M, Uddin SMM, Haq A, Yaqoob U. The clinicopathological profile of eosinophilic myocarditis. Cureus. 2018;10(12):e3677.","journal-title":"Cureus"},{"key":"2286_CR37","doi-asserted-by":"crossref","unstructured":"Abedin N, Seemann T, Kleinfeld S, Ruehrup J, Roseler S, Trautwein C et al: Fecal eosinophil cationic protein is a diagnostic and predictive biomarker in young adults with inflammatory bowel disease. J Clin Med 2019, 8(12). PMID 31756948.","DOI":"10.3390\/jcm8122025"},{"issue":"9","key":"2286_CR38","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.3899\/jrheum.170373","volume":"44","author":"H Hozumi","year":"2017","unstructured":"Hozumi H, Fujisawa T, Enomoto N, Nakashima R, Enomoto Y, Suzuki Y, et al. Clinical utility of YKL-40 in polymyositis\/dermatomyositis-associated interstitial lung disease. J Rheumatol. 2017;44(9):1394\u2013401.","journal-title":"J Rheumatol"},{"issue":"1","key":"2286_CR39","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13075-016-1214-8","volume":"19","author":"Y Enomoto","year":"2017","unstructured":"Enomoto Y, Suzuki Y, Hozumi H, Mori K, Kono M, Karayama M, et al. Clinical significance of soluble CD163 in polymyositis-related or dermatomyositis-related interstitial lung disease. Arthritis Res Ther. 2017;19(1):9.","journal-title":"Arthritis Res Ther"},{"issue":"6","key":"2286_CR40","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1093\/rheumatology\/key420","volume":"58","author":"S Takanashi","year":"2019","unstructured":"Takanashi S, Nishina N, Nakazawa M, Kaneko Y, Takeuchi T. Usefulness of serum Krebs von den Lungen-6 for the management of myositis-associated interstitial lung disease. Rheumatology (Oxford). 2019;58(6):1034\u20139.","journal-title":"Rheumatology (Oxford)"},{"issue":"3","key":"2286_CR41","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/rheumatology\/key341","volume":"58","author":"K Wang","year":"2019","unstructured":"Wang K, Zhao J, Chen Z, Li T, Tan X, Zheng Y, et al. CD4+CXCR4+ T cells as a novel prognostic biomarker in patients with idiopathic inflammatory myopathy-associated interstitial lung disease. Rheumatology (Oxford). 2019;58(3):511\u201321.","journal-title":"Rheumatology (Oxford)"},{"issue":"2","key":"2286_CR42","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3109\/03009742.2016.1167950","volume":"46","author":"Z Jiang","year":"2017","unstructured":"Jiang Z, Tao JH, Zuo T, Li XM, Wang GS, Fang X, et al. The correlation between miR-200c and the severity of interstitial lung disease associated with different connective tissue diseases. Scand J Rheumatol. 2017;46(2):122\u20139.","journal-title":"Scand J Rheumatol"},{"issue":"12","key":"2286_CR43","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1093\/rheumatology\/kez185","volume":"58","author":"Y Horiike","year":"2019","unstructured":"Horiike Y, Suzuki Y, Fujisawa T, Yasui H, Karayama M, Hozumi H, et al. Successful classification of macrophage-mannose receptor CD206 in severity of anti-MDA5 antibody positive dermatomyositis associated ILD. Rheumatology (Oxford). 2019;58(12):2143\u201352.","journal-title":"Rheumatology (Oxford)"},{"key":"2286_CR44","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s13075-015-0547-z","volume":"17","author":"A Tanaka","year":"2015","unstructured":"Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, et al. Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis. Arthritis Res Ther. 2015;17:27.","journal-title":"Arthritis Res Ther"},{"issue":"2","key":"2286_CR45","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1590\/s1677-5538.ibju.2017.0173","volume":"44","author":"L Canat","year":"2018","unstructured":"Canat L, Ataly HA, Agalarov S, Alkan I, Altunrende F. The effect of AST\/ALT (De Ritis) ratio on survival and its relation to tumor histopathological variables in patients with localized renal cell carcinoma. Int Braz J Urol. 2018;44(2):288\u201395.","journal-title":"Int Braz J Urol"},{"issue":"1","key":"2286_CR46","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1186\/s12885-019-6011-8","volume":"19","author":"LX Zhang","year":"2019","unstructured":"Zhang LX, Lv Y, Xu AM, Wang HZ. The prognostic significance of serum gamma-glutamyltransferase levels and AST\/ALT in primary hepatic carcinoma. BMC Cancer. 2019;19(1):841.","journal-title":"BMC Cancer"},{"issue":"2","key":"2286_CR47","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1183\/09031936.03.00026703","volume":"22","author":"V Cottin","year":"2003","unstructured":"Cottin V, Thivolet-Bejui F, Reynaud-Gaubert M, Cadranel J, Delaval P, Ternamian PJ, et al. Interstitial lung disease in amyopathic dermatomyositis, dermatomyositis and polymyositis. Eur Respir J. 2003;22(2):245\u201350.","journal-title":"Eur Respir J"},{"key":"2286_CR48","doi-asserted-by":"crossref","unstructured":"Kang EH, Lee EB, Shin KC, Im CH, Chung DH, Han SK, et al. Interstitial lung disease in patients with polymyositis, dermatomyositis and amyopathic dermatomyositis. Rheumatology (Oxford). 2005;44(10):1282\u20136.","DOI":"10.1093\/rheumatology\/keh723"},{"issue":"39","key":"2286_CR49","doi-asserted-by":"crossref","first-page":"e4911","DOI":"10.1097\/MD.0000000000004911","volume":"95","author":"S Sanges","year":"2016","unstructured":"Sanges S, Yelnik CM, Sitbon O, Benveniste O, Mariampillai K, Phillips-Houlbracq M, et al. Pulmonary arterial hypertension in idiopathic inflammatory myopathies: data from the French pulmonary hypertension registry and review of the literature. Medicine (Baltimore). 2016;95(39):e4911.","journal-title":"Medicine (Baltimore)"},{"key":"2286_CR50","doi-asserted-by":"crossref","unstructured":"Yang X, Hao Y, Zhang X, Geng Y, Ji L, Li G, et al. Mortality of Chinese patients with polymyositis and dermatomyositis. Clin Rheumatol. 2020. PMID 31902027.","DOI":"10.1007\/s10067-019-04910-w"}],"container-title":["Arthritis Research &amp; Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13075-020-02286-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13075-020-02286-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13075-020-02286-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,19]],"date-time":"2021-09-19T19:05:52Z","timestamp":1632078352000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/s13075-020-02286-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,20]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["2286"],"URL":"https:\/\/doi.org\/10.1186\/s13075-020-02286-w","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-25060\/v1","asserted-by":"object"}]},"ISSN":["1478-6362"],"issn-type":[{"value":"1478-6362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,20]]},"assertion":[{"value":"23 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by Institutional Review Board of West China Hospital, Sichuan University.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"202"}}