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The case group had a higher proportion of abdominal pain, vomiting, abdominal distension, pleural effusion, Raynaud\u2019s phenomenon (RP), splenic infarction, and concurrent macrophage activation syndrome (MAS) than the control group, with a statistically significant difference (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). Serum ferritin (SF), alanine transaminase (ALT), aspartate transaminase (AST), lactate dehydrogenase (LDH), amylase, and increased 24-h urine protein levels were statistically different between the two groups (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05); platelet counts (PLT) reduction was also statistically different (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). The case group had a higher proportion of methylprednisolone pulse therapy, cyclophosphamide pulse therapy during remission induction, and therapeutic plasma exchange than the control group, with a statistically significant difference (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05) between the two.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CSLE-associated pancreatitis has a high fatality rate. The presence of RP, splenic infarction, pleural effusion, and MAS warrants attention from clinicians regarding the possibility of pancreatitis. Once pancreatitis is detected, the primary disease needs active treatment for better prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13075-024-03265-1","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T01:01:57Z","timestamp":1705453317000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Children systemic lupus erythematosus-associated pancreatitis"],"prefix":"10.1186","volume":"26","author":[{"given":"Dan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianming","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaixiu","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjie","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"issue":"11","key":"3265_CR1","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1177\/0961203317707825","volume":"26","author":"Z Li","year":"2017","unstructured":"Li Z, Xu D, Wang Z, Wang Y, Li M, Zeng X. 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