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The Utrecht ethical consent was covered under protocols 16\u2013178, 16\u2013474, and 25\u20130401. Data collection for the Hospital for Special Surgery was approved by IRB - The Established Still\u2019s Disease Cohort (#2022\u2009\u2212\u20091072).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Bella Mehta: Tonix Pharmaceuticals and Janssen Pharmaceuticals \u2013 advisory board (one time only)Helen Leavis: Consultancy Sobi & Novartis (Takeda, Octapharma), Grants (Takeda), CSL BehringBas Vastert: one unrestricted research grant from Sobi, in a public-private grant mechanism with ZonMw (the ESTIS trial), and report consultancy fees from Sobi and Novartis.Grant Schulert: research support from IpiNovyx, consulting fees from SOBI and Novartis.All other authors report no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"124"}}