{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:43:36Z","timestamp":1787168616064,"version":"build-2736575974"},"reference-count":179,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Deanship of Research and Graduate Studies at King Khalid University","award":["RGP-2\/202\/45"],"award-info":[{"award-number":["RGP-2\/202\/45"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Gut Pathog"],"DOI":"10.1186\/s13099-025-00702-7","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T03:08:34Z","timestamp":1750129714000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The role of probiotics in promoting systemic immune tolerance in systemic lupus erythematosus"],"prefix":"10.1186","volume":"17","author":[{"given":"Asma\u2019a H.","family":"Mohamed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa","family":"Shafie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rithab Ibrahim","family":"Al-Samawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Chand","family":"Jamali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal Adnan","family":"Ashour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Fareed","family":"Felemban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alqarni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irshad","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasrin","family":"Mansuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuzail","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adil Abdelrahim Mohammed","family":"Yousif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,17]]},"reference":[{"issue":"4","key":"702_CR1","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1038\/nri.2017.7","volume":"17","author":"M Levy","year":"2017","unstructured":"Levy M, et al. Dysbiosis and the immune system. Nat Rev Immunol. 2017;17(4):219\u201332.","journal-title":"Nat Rev Immunol"},{"key":"702_CR2","doi-asserted-by":"crossref","unstructured":"Davidson A, Diamond B. General features of autoimmune disease, in The autoimmune diseases. Elsevier; 2020. pp. 17\u201344.","DOI":"10.1016\/B978-0-12-812102-3.00003-8"},{"key":"702_CR3","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/hae.13445","volume":"24","author":"HH Brackmann","year":"2018","unstructured":"Brackmann HH, et al. Immune tolerance induction: what have we learned over time? Haemophilia. 2018;24:3\u201314.","journal-title":"Haemophilia"},{"issue":"2","key":"702_CR4","doi-asserted-by":"publisher","first-page":"103236","DOI":"10.1016\/j.autrev.2022.103236","volume":"22","author":"K Bieber","year":"2023","unstructured":"Bieber K, et al. Autoimmune pre-disease. Autoimmun Rev. 2023;22(2):103236.","journal-title":"Autoimmun Rev"},{"issue":"3","key":"702_CR5","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s40744-020-00212-9","volume":"7","author":"F Basta","year":"2020","unstructured":"Basta F, et al. Systemic lupus erythematosus (SLE) therapy: the old and the new. Rheumatol Therapy. 2020;7(3):433\u201346.","journal-title":"Rheumatol Therapy"},{"key":"702_CR6","doi-asserted-by":"crossref","unstructured":"Ameer MA et al. An overview of systemic lupus erythematosus (SLE) pathogenesis, classification, and management. Cureus. 2022;14(10).","DOI":"10.7759\/cureus.30330"},{"key":"702_CR7","doi-asserted-by":"crossref","unstructured":"Mu Q, Zhang H, Luo XM. SLE: another autoimmune disorder influenced by microbes and diet? Front Immunol. 2015;6:166179.","DOI":"10.3389\/fimmu.2015.00608"},{"issue":"9","key":"702_CR8","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1038\/s41584-021-00668-1","volume":"17","author":"MR Barber","year":"2021","unstructured":"Barber MR, et al. Global epidemiology of systemic lupus erythematosus. Nat Rev Rheumatol. 2021;17(9):515\u201332.","journal-title":"Nat Rev Rheumatol"},{"key":"702_CR9","doi-asserted-by":"crossref","unstructured":"Nikolopoulos DS, et al. Transition to severe phenotype in systemic lupus erythematosus initially presenting with non-severe disease: implications for the management of early disease. Lupus Sci Med. 2020;7(1):e000394.","DOI":"10.1136\/lupus-2020-000394"},{"key":"702_CR10","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.comppsych.2017.09.007","volume":"80","author":"A Mani","year":"2018","unstructured":"Mani A, et al. Temperament and character in patients with systemic lupus erythematosus. Compr Psychiatr. 2018;80:104\u20138.","journal-title":"Compr Psychiatr"},{"key":"702_CR11","doi-asserted-by":"crossref","unstructured":"Beckerman NL, Auerbach C, Blanco I. Psychosocial dimensions of SLE: implications for the health care team. J Multidisciplinary Healthc. 2011;4:63\u201372.","DOI":"10.2147\/JMDH.S19303"},{"key":"702_CR12","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.3389\/fimmu.2020.01477","volume":"11","author":"MA Islam","year":"2020","unstructured":"Islam MA, et al. Immunomodulatory effects of diet and nutrients in systemic lupus erythematosus (SLE): a systematic review. Front Immunol. 2020;11:1477.","journal-title":"Front Immunol"},{"issue":"1","key":"702_CR13","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1017\/S0954422417000026","volume":"30","author":"M Aparicio-Soto","year":"2017","unstructured":"Aparicio-Soto M, S\u00e1nchez-Hidalgo M, Alarc\u00f3n-de-la-Lastra. An update on diet and nutritional factors in systemic lupus erythematosus management. Nutr Res Rev. 2017;30(1):118\u201337.","journal-title":"Nutr Res Rev"},{"key":"702_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jaut.2018.11.001","volume":"96","author":"A Fava","year":"2019","unstructured":"Fava A, Petri M. Systemic lupus erythematosus: diagnosis and clinical management. J Autoimmun. 2019;96:1\u201313.","journal-title":"J Autoimmun"},{"issue":"1","key":"702_CR15","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1136\/annrheumdis-2020-218272","volume":"80","author":"A Fanouriakis","year":"2021","unstructured":"Fanouriakis A, et al. Update \u039fn the diagnosis and management of systemic lupus erythematosus. Ann Rheum Dis. 2021;80(1):14\u201325.","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"702_CR16","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/s00011-022-01554-6","volume":"71","author":"N Bolouri","year":"2022","unstructured":"Bolouri N, et al. Role of the innate and adaptive immune responses in the pathogenesis of systemic lupus erythematosus. Inflamm Res. 2022;71(5):537\u201354.","journal-title":"Inflamm Res"},{"issue":"3","key":"702_CR17","doi-asserted-by":"publisher","first-page":"712","DOI":"10.3390\/jcm9030712","volume":"9","author":"E Demirkaya","year":"2020","unstructured":"Demirkaya E, et al. New horizons in the genetic etiology of systemic lupus erythematosus and lupus-like disease: monogenic lupus and beyond. J Clin Med. 2020;9(3):712.","journal-title":"J Clin Med"},{"issue":"6","key":"702_CR18","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1111\/joim.13448","volume":"291","author":"JM Woo","year":"2022","unstructured":"Woo JM, et al. The role of environmental exposures and gene\u2013environment interactions in the etiology of systemic lupus erythematous. J Intern Med. 2022;291(6):755\u201378.","journal-title":"J Intern Med"},{"key":"702_CR19","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.clim.2019.06.003","volume":"205","author":"R Gonzalez-Quintial","year":"2019","unstructured":"Gonzalez-Quintial R, et al. Silica exposure and chronic virus infection synergistically promote lupus-like systemic autoimmunity in mice with low genetic predisposition. Clin Immunol. 2019;205:75\u201382.","journal-title":"Clin Immunol"},{"issue":"3","key":"702_CR20","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/imm.13103","volume":"158","author":"R Illescas-Montes","year":"2019","unstructured":"Illescas-Montes R, et al. Infectious processes and systemic lupus erythematosus. Immunology. 2019;158(3):153\u201360.","journal-title":"Immunology"},{"issue":"4","key":"702_CR21","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.rdc.2022.06.005","volume":"48","author":"JL Liu","year":"2022","unstructured":"Liu JL, et al. Systemic lupus erythematosus risk: the role of environmental factors. Rheumatic Disease Clin. 2022;48(4):827\u201343.","journal-title":"Rheumatic Disease Clin"},{"issue":"5","key":"702_CR22","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1136\/annrheumdis-2020-219065","volume":"80","author":"E Ha","year":"2021","unstructured":"Ha E, Bae S-C, Kim K. Large-scale meta-analysis across East Asian and European populations updated genetic architecture and variant-driven biology of rheumatoid arthritis, identifying 11 novel susceptibility loci. Ann Rheum Dis. 2021;80(5):558\u201365.","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"702_CR23","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.3390\/cells8101180","volume":"8","author":"Y-C Kwon","year":"2019","unstructured":"Kwon Y-C, et al. Update on the genetics of systemic lupus erythematosus: genome-wide association studies and beyond. Cells. 2019;8(10):1180.","journal-title":"Cells"},{"key":"702_CR24","doi-asserted-by":"publisher","first-page":"1398035","DOI":"10.3389\/flupu.2024.1398035","volume":"2","author":"V Laurynenka","year":"2024","unstructured":"Laurynenka V, Harley JB. The 330 risk loci known for systemic lupus erythematosus (SLE): a review. Front Lupus. 2024;2:1398035.","journal-title":"Front Lupus"},{"key":"702_CR25","doi-asserted-by":"publisher","first-page":"144713","DOI":"10.3389\/fimmu.2015.00228","volume":"6","author":"S Han","year":"2015","unstructured":"Han S, et al. Mechanisms of autoantibody production in systemic lupus erythematosus. Front Immunol. 2015;6:144713.","journal-title":"Front Immunol"},{"issue":"2","key":"702_CR26","doi-asserted-by":"publisher","first-page":"e32001","DOI":"10.1371\/journal.pone.0032001","volume":"7","author":"KH Ching","year":"2012","unstructured":"Ching KH, et al. Two major autoantibody clusters in systemic lupus erythematosus. PLoS ONE. 2012;7(2):e32001.","journal-title":"PLoS ONE"},{"issue":"2","key":"702_CR27","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.cyto.2014.12.027","volume":"72","author":"RM Talaat","year":"2015","unstructured":"Talaat RM, et al. Th1\/Th2\/Th17\/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: correlation with disease activity. Cytokine. 2015;72(2):146\u201353.","journal-title":"Cytokine"},{"issue":"12","key":"702_CR28","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1038\/nri2889","volume":"10","author":"JH Buckner","year":"2010","unstructured":"Buckner JH. Mechanisms of impaired regulation by CD4\u2009+\u2009CD25\u2009+\u2009FOXP3\u2009+\u2009regulatory T cells in human autoimmune diseases. Nat Rev Immunol. 2010;10(12):849\u201359.","journal-title":"Nat Rev Immunol"},{"issue":"9","key":"702_CR29","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1038\/ni0901-816","volume":"2","author":"KJ Maloy","year":"2001","unstructured":"Maloy KJ, Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol. 2001;2(9):816\u201322.","journal-title":"Nat Immunol"},{"issue":"19","key":"702_CR30","doi-asserted-by":"publisher","first-page":"7015","DOI":"10.3390\/ijms21197015","volume":"21","author":"PJ Eggenhuizen","year":"2020","unstructured":"Eggenhuizen PJ, Ng BH, Ooi JD. Treg enhancing therapies to treat autoimmune diseases. Int J Mol Sci. 2020;21(19):7015.","journal-title":"Int J Mol Sci"},{"key":"702_CR31","doi-asserted-by":"publisher","first-page":"102461","DOI":"10.1016\/j.jaut.2020.102461","volume":"111","author":"X Zhang","year":"2020","unstructured":"Zhang X, Olsen N, Zheng SG. The progress and prospect of regulatory T cells in autoimmune diseases. J Autoimmun. 2020;111:102461.","journal-title":"J Autoimmun"},{"issue":"5","key":"702_CR32","doi-asserted-by":"publisher","first-page":"102715","DOI":"10.1016\/j.autrev.2020.102715","volume":"20","author":"R Zhang","year":"2021","unstructured":"Zhang R, Miao J, Zhu P. Regulatory T cell heterogeneity and therapy in autoimmune diseases. Autoimmun Rev. 2021;20(5):102715.","journal-title":"Autoimmun Rev"},{"issue":"1","key":"702_CR33","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3109\/08923973.2014.968255","volume":"37","author":"F Lavi Arab","year":"2015","unstructured":"Lavi Arab F, et al. Assessment of 1, 25-dihydroxyvitamin D3 effects on Treg cells in a mouse model of systemic lupus erythematosus. Immunopharmacol Immunotoxicol. 2015;37(1):12\u20138.","journal-title":"Immunopharmacol Immunotoxicol"},{"issue":"2","key":"702_CR34","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.clim.2011.08.005","volume":"141","author":"S Dolff","year":"2011","unstructured":"Dolff S, et al. Disturbed Th1, Th2, Th17 and Treg balance in patients with systemic lupus erythematosus. Clin Immunol. 2011;141(2):197\u2013204.","journal-title":"Clin Immunol"},{"key":"702_CR35","doi-asserted-by":"crossref","unstructured":"Muhammad Yusoff F, Wong KK, Mohd Redzwan N. Th1, Th2, and Th17 cytokines in systemic lupus erythematosus. Autoimmunity. 2020;53(1):8\u201320.","DOI":"10.1080\/08916934.2019.1693545"},{"key":"702_CR36","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.rbr.2015.08.008","volume":"56","author":"JAP Ara\u00fajo","year":"2016","unstructured":"Ara\u00fajo JAP, et al. Th17 cells and CD4\u2009+\u2009multifunctional T cells in patients with systemic lupus erythematosus. Revista Brasileira De Reumatologia. 2016;56:28\u201336.","journal-title":"Revista Brasileira De Reumatologia"},{"key":"702_CR37","doi-asserted-by":"crossref","unstructured":"Qu N et al. Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases. J Immunol Res. 2013;2013.","DOI":"10.1155\/2013\/968549"},{"issue":"3","key":"702_CR38","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.clim.2008.01.019","volume":"127","author":"CK Wong","year":"2008","unstructured":"Wong CK, et al. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. Clin Immunol. 2008;127(3):385\u201393.","journal-title":"Clin Immunol"},{"issue":"1","key":"702_CR39","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1177\/1535370218824547","volume":"244","author":"M Larosa","year":"2019","unstructured":"Larosa M, et al. IL-12 and IL-23\/Th17 axis in systemic lupus erythematosus. Experimental Biology Med. 2019;244(1):42\u201351.","journal-title":"Experimental Biology Med"},{"key":"702_CR40","first-page":"1","volume":"11","author":"M Rojas","year":"2018","unstructured":"Rojas M, et al. Cytokines and inflammatory mediators in systemic lupus erythematosus. Rheumatology. 2018;11:1\u20135.","journal-title":"Rheumatology"},{"issue":"21","key":"702_CR41","doi-asserted-by":"publisher","first-page":"11327","DOI":"10.3390\/ijms222111327","volume":"22","author":"H Idborg","year":"2021","unstructured":"Idborg H, Oke V. Cytokines as biomarkers in systemic lupus erythematosus: value for diagnosis and drug therapy. Int J Mol Sci. 2021;22(21):11327.","journal-title":"Int J Mol Sci"},{"issue":"1","key":"702_CR42","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1111\/imr.12374","volume":"269","author":"AC Lino","year":"2016","unstructured":"Lino AC, et al. Cytokine-producing B cells: a translational view on their roles in human and mouse autoimmune diseases. Immunol Rev. 2016;269(1):130\u201344.","journal-title":"Immunol Rev"},{"issue":"1","key":"702_CR43","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.cyto.2015.07.005","volume":"76","author":"P Pandiyan","year":"2015","unstructured":"Pandiyan P, Zhu J. Origin and functions of pro-inflammatory cytokine producing Foxp3\u2009+\u2009regulatory T cells. Cytokine. 2015;76(1):13\u201324.","journal-title":"Cytokine"},{"key":"702_CR44","doi-asserted-by":"crossref","unstructured":"Su D-L et al. Roles of pro-and anti-inflammatory cytokines in the pathogenesis of SLE. Biomed Res Int. 2012;2012.","DOI":"10.1155\/2012\/347141"},{"key":"702_CR45","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.jaut.2016.08.001","volume":"74","author":"M Teruel","year":"2016","unstructured":"Teruel M, Alarc\u00f3n-Riquelme ME. The genetic basis of systemic lupus erythematosus: what are the risk factors and what have we learned. J Autoimmun. 2016;74:161\u201375.","journal-title":"J Autoimmun"},{"issue":"1","key":"702_CR46","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.gene.2013.08.051","volume":"533","author":"J Zhang","year":"2014","unstructured":"Zhang J, et al. Association study of TLR-9 polymorphisms and systemic lupus erythematosus in Northern Chinese Han population. Gene. 2014;533(1):385\u20138.","journal-title":"Gene"},{"issue":"12","key":"702_CR47","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.1084\/jem.20030152","volume":"198","author":"W Chen","year":"2003","unstructured":"Chen W, et al. Conversion of peripheral CD4\u2009+\u2009CD25\u2013naive T cells to CD4\u2009+\u2009CD25\u2009+\u2009regulatory T cells by TGF-\u03b2 induction of transcription factor Foxp3. J Exp Med. 2003;198(12):1875\u201386.","journal-title":"J Exp Med"},{"issue":"5","key":"702_CR48","doi-asserted-by":"publisher","first-page":"3093","DOI":"10.4049\/jimmunol.173.5.3093","volume":"173","author":"LA Wolfraim","year":"2004","unstructured":"Wolfraim LA, et al. p21Cip1 and p27Kip1 act in synergy to alter the sensitivity of Naive T cells to TGF-\u03b2-mediated G1 arrest through modulation of IL-2 responsiveness. J Immunol. 2004;173(5):3093\u2013102.","journal-title":"J Immunol"},{"issue":"8","key":"702_CR49","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.1002\/jcp.25748","volume":"232","author":"SA Esmaeili","year":"2017","unstructured":"Esmaeili SA, et al. Tolerogenic probiotics: potential immunoregulators in systemic lupus erythematosus. J Cell Physiol. 2017;232(8):1994\u20132007.","journal-title":"J Cell Physiol"},{"issue":"2","key":"702_CR50","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/nrrheum.2013.157","volume":"10","author":"W Xiong","year":"2014","unstructured":"Xiong W, Lahita RG. Pragmatic approaches to therapy for systemic lupus erythematosus. Nat Rev Rheumatol. 2014;10(2):97\u2013107.","journal-title":"Nat Rev Rheumatol"},{"issue":"6","key":"702_CR51","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1136\/annrheumdis-2019-215089","volume":"78","author":"A Fanouriakis","year":"2019","unstructured":"Fanouriakis A, et al. 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus. Ann Rheum Dis. 2019;78(6):736\u201345.","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"702_CR52","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.3390\/microorganisms8101587","volume":"8","author":"JY Yoo","year":"2020","unstructured":"Yoo JY, et al. Gut microbiota and immune system interactions. Microorganisms. 2020;8(10):1587.","journal-title":"Microorganisms"},{"issue":"7164","key":"702_CR53","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1038\/nature06244","volume":"449","author":"PJ Turnbaugh","year":"2007","unstructured":"Turnbaugh PJ, et al. The human microbiome project. Nature. 2007;449(7164):804\u201310.","journal-title":"Nature"},{"key":"702_CR54","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.1093\/advances\/nmy078","volume":"10","author":"A Cuevas-Sierra","year":"2019","unstructured":"Cuevas-Sierra A, et al. Diet, gut microbiota, and obesity: links with host genetics and epigenetics and potential applications. Adv Nutr. 2019;10:S17\u201330.","journal-title":"Adv Nutr"},{"issue":"9","key":"702_CR55","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1038\/s41579-020-0367-2","volume":"18","author":"WE Ruff","year":"2020","unstructured":"Ruff WE, Greiling TM, Kriegel MA. Host\u2013microbiota interactions in immune-mediated diseases. Nat Rev Microbiol. 2020;18(9):521\u201338.","journal-title":"Nat Rev Microbiol"},{"issue":"9","key":"702_CR56","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1016\/j.molmed.2020.04.001","volume":"26","author":"X Zhang","year":"2020","unstructured":"Zhang X, Zhao L-d, Li H. The gut microbiota: emerging evidence in autoimmune diseases. Trends Mol Med. 2020;26(9):862\u201373.","journal-title":"Trends Mol Med"},{"key":"702_CR57","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1007\/s00005-019-00561-6","volume":"67","author":"M Grochowska","year":"2019","unstructured":"Grochowska M, Laskus T, Radkowski M. Gut microbiota in neurological disorders. Arch Immunol Ther Exp. 2019;67:375\u201383.","journal-title":"Arch Immunol Ther Exp"},{"issue":"6","key":"702_CR58","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.nrleng.2019.03.026","volume":"37","author":"F Castillo-\u00c1lvarez","year":"2022","unstructured":"Castillo-\u00c1lvarez F, Marzo-Sola M. Role of the gut microbiota in the development of various neurological diseases. Neurolog\u00eda (English Edition). 2022;37(6):492\u20138.","journal-title":"Neurolog\u00eda (English Edition)"},{"issue":"4","key":"702_CR59","doi-asserted-by":"publisher","first-page":"e02288","DOI":"10.1128\/AEM.02288-17","volume":"84","author":"XM Luo","year":"2018","unstructured":"Luo XM, et al. Gut microbiota in human systemic lupus erythematosus and a mouse model of lupus. Appl Environ Microbiol. 2018;84(4):e02288\u201317.","journal-title":"Appl Environ Microbiol"},{"key":"702_CR60","doi-asserted-by":"publisher","first-page":"269575","DOI":"10.3389\/fimmu.2017.00598","volume":"8","author":"Q Mu","year":"2017","unstructured":"Mu Q, et al. Leaky gut as a danger signal for autoimmune diseases. Front Immunol. 2017;8:269575.","journal-title":"Front Immunol"},{"issue":"12","key":"702_CR61","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/s11926-023-01115-8","volume":"25","author":"FNC Kalayci","year":"2023","unstructured":"Kalayci FNC, Ozen S. Possible role of dysbiosis of the gut microbiome in Sle. Curr Rheumatol Rep. 2023;25(12):247\u201358.","journal-title":"Curr Rheumatol Rep"},{"issue":"10","key":"702_CR62","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1080\/1744666X.2018.1519395","volume":"14","author":"L Ruiz","year":"2018","unstructured":"Ruiz L, et al. The role of gut microbiota in lupus: what we know in 2018? Expert Rev Clin Immunol. 2018;14(10):787\u201392.","journal-title":"Expert Rev Clin Immunol"},{"key":"702_CR63","doi-asserted-by":"publisher","first-page":"759095","DOI":"10.3389\/fphar.2021.759095","volume":"12","author":"X Guo","year":"2021","unstructured":"Guo X, et al. The microbiota in systemic lupus erythematosus: an update on the potential function of probiotics. Front Pharmacol. 2021;12:759095.","journal-title":"Front Pharmacol"},{"key":"702_CR64","doi-asserted-by":"crossref","unstructured":"de Oliveira GL. Probiotic applications in autoimmune diseases. Probiotics-Current Knowledge and Future Prospects. 2018;Chapter 4:69\u201389.","DOI":"10.5772\/intechopen.73064"},{"key":"702_CR65","doi-asserted-by":"crossref","unstructured":"Azad MAK, Sarker M, Wan D. Immunomodulatory effects of probiotics on cytokine profiles. Biomed Res Int. 2018;2018.","DOI":"10.1155\/2018\/8063647"},{"key":"702_CR66","doi-asserted-by":"publisher","first-page":"616713","DOI":"10.3389\/fimmu.2021.616713","volume":"12","author":"A Raheem","year":"2021","unstructured":"Raheem A, et al. Modulatory effects of probiotics during pathogenic infections with emphasis on immune regulation. Front Immunol. 2021;12:616713.","journal-title":"Front Immunol"},{"issue":"2","key":"702_CR67","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1080\/19490976.2015.1031946","volume":"6","author":"H Zhang","year":"2015","unstructured":"Zhang H, Luo XM. Control of commensal microbiota by the adaptive immune system. Gut Microbes. 2015;6(2):156\u201360.","journal-title":"Gut Microbes"},{"issue":"3","key":"702_CR68","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1038\/nri.2015.17","volume":"16","author":"A Perez-Lopez","year":"2016","unstructured":"Perez-Lopez A, et al. Mucosal immunity to pathogenic intestinal bacteria. Nat Rev Immunol. 2016;16(3):135\u201348.","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"702_CR69","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.pathophys.2016.02.002","volume":"23","author":"CR Webb","year":"2016","unstructured":"Webb CR, et al. Protective and pro-inflammatory roles of intestinal bacteria. Pathophysiology. 2016;23(2):67\u201380.","journal-title":"Pathophysiology"},{"issue":"33","key":"702_CR70","doi-asserted-by":"publisher","first-page":"14691","DOI":"10.1073\/pnas.1005963107","volume":"107","author":"C De Filippo","year":"2010","unstructured":"De Filippo C, et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci. 2010;107(33):14691\u20136.","journal-title":"Proc Natl Acad Sci"},{"issue":"11","key":"702_CR71","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1038\/nrendo.2011.126","volume":"7","author":"NM Delzenne","year":"2011","unstructured":"Delzenne NM, et al. Targeting gut microbiota in obesity: effects of prebiotics and probiotics. Nat Reviews Endocrinol. 2011;7(11):639\u201346.","journal-title":"Nat Reviews Endocrinol"},{"issue":"3","key":"702_CR72","doi-asserted-by":"publisher","first-page":"202","DOI":"10.4103\/0255-0857.53201","volume":"27","author":"V Gupta","year":"2009","unstructured":"Gupta V, Garg R. Probiotics. Ind J Med Microbiol. 2009;27(3):202\u20139.","journal-title":"Ind J Med Microbiol"},{"issue":"17","key":"702_CR73","doi-asserted-by":"publisher","first-page":"4342","DOI":"10.3390\/cancers13174342","volume":"13","author":"J Giraud","year":"2021","unstructured":"Giraud J, Saleh M. Host\u2013Microbiota interactions in liver inflammation and cancer. Cancers. 2021;13(17):4342.","journal-title":"Cancers"},{"issue":"7195","key":"702_CR74","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1038\/nature07008","volume":"453","author":"SK Mazmanian","year":"2008","unstructured":"Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature. 2008;453(7195):620\u20135.","journal-title":"Nature"},{"issue":"5","key":"702_CR75","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1038\/nri2515","volume":"9","author":"JL Round","year":"2009","unstructured":"Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol. 2009;9(5):313\u201323.","journal-title":"Nat Rev Immunol"},{"issue":"suppl2","key":"702_CR76","doi-asserted-by":"publisher","first-page":"S129","DOI":"10.1093\/cid\/civ085","volume":"60","author":"S Doron","year":"2015","unstructured":"Doron S, Snydman DR. Risk and safety of probiotics. Clin Infect Dis. 2015;60(suppl2):S129\u201334.","journal-title":"Clin Infect Dis"},{"issue":"1","key":"702_CR77","first-page":"011","volume":"7","author":"CR Soccol","year":"2014","unstructured":"Soccol CR, et al. Current developments in probiotics. J Microb Biochem Technol. 2014;7(1):011\u201320.","journal-title":"J Microb Biochem Technol"},{"issue":"2","key":"702_CR78","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.3390\/ijms24021806","volume":"24","author":"L Calvo-Barreiro","year":"2023","unstructured":"Calvo-Barreiro L, et al. Gut microbial-derived metabolites as immune modulators of T helper 17 and regulatory T cells. Int J Mol Sci. 2023;24(2):1806.","journal-title":"Int J Mol Sci"},{"issue":"8","key":"702_CR79","doi-asserted-by":"publisher","first-page":"2850","DOI":"10.1128\/AEM.07581-11","volume":"78","author":"P L\u00f3pez","year":"2012","unstructured":"L\u00f3pez P, et al. Interaction of bifidobacterium bifidum LMG13195 with HT29 cells influences regulatory-T-cell-associated chemokine receptor expression. Appl Environ Microbiol. 2012;78(8):2850\u20137.","journal-title":"Appl Environ Microbiol"},{"issue":"7","key":"702_CR80","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1080\/10408398.2011.619671","volume":"54","author":"R Ashraf","year":"2014","unstructured":"Ashraf R, Shah NP. Immune system stimulation by probiotic microorganisms. Crit Rev Food Sci Nutr. 2014;54(7):938\u201356.","journal-title":"Crit Rev Food Sci Nutr"},{"issue":"6","key":"702_CR81","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.it.2011.04.003","volume":"32","author":"M Rescigno","year":"2011","unstructured":"Rescigno M. The intestinal epithelial barrier in the control of homeostasis and immunity. Trends Immunol. 2011;32(6):256\u201364.","journal-title":"Trends Immunol"},{"key":"702_CR82","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s00203-014-1034-7","volume":"197","author":"AK Yadav","year":"2015","unstructured":"Yadav AK, et al. Adhesion of indigenous Lactobacillus plantarum to gut extracellular matrix and its physicochemical characterization. Arch Microbiol. 2015;197:155\u201364.","journal-title":"Arch Microbiol"},{"issue":"8","key":"702_CR83","doi-asserted-by":"publisher","first-page":"fnw050","DOI":"10.1093\/femsle\/fnw050","volume":"363","author":"JK Das","year":"2016","unstructured":"Das JK, et al. Lactobacillus acidophilus binds to MUC3 component of cultured intestinal epithelial cells with highest affinity. FEMS Microbiol Lett. 2016;363(8):fnw050.","journal-title":"FEMS Microbiol Lett"},{"issue":"6","key":"702_CR84","doi-asserted-by":"publisher","first-page":"G807","DOI":"10.1152\/ajpgi.00243.2009","volume":"298","author":"CL Ohland","year":"2010","unstructured":"Ohland CL, MacNaughton WK. Probiotic bacteria and intestinal epithelial barrier function. Am J physiology-gastrointestinal Liver Physiol. 2010;298(6):G807\u201319.","journal-title":"Am J physiology-gastrointestinal Liver Physiol"},{"issue":"4","key":"702_CR85","doi-asserted-by":"publisher","first-page":"657","DOI":"10.3390\/cells12040657","volume":"12","author":"E Fock","year":"2023","unstructured":"Fock E, Parnova R. Mechanisms of blood\u2013brain barrier protection by microbiota-derived short-chain fatty acids. Cells. 2023;12(4):657.","journal-title":"Cells"},{"key":"702_CR86","doi-asserted-by":"publisher","first-page":"402","DOI":"10.3389\/fncel.2019.00402","volume":"13","author":"S Ahmed","year":"2019","unstructured":"Ahmed S, et al. In vitro characterization of gut microbiota-derived bacterial strains with neuroprotective properties. Front Cell Neurosci. 2019;13:402.","journal-title":"Front Cell Neurosci"},{"key":"702_CR87","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.coi.2016.12.001","volume":"44","author":"V Woo","year":"2017","unstructured":"Woo V, Alenghat T. Host\u2013microbiota interactions: epigenomic regulation. Curr Opin Immunol. 2017;44:52\u201360.","journal-title":"Curr Opin Immunol"},{"issue":"1","key":"702_CR88","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1186\/s12974-023-02808-8","volume":"20","author":"Y Meng","year":"2023","unstructured":"Meng Y, et al. Lactobacillus paracasei L9 affects disease progression in experimental autoimmune neuritis by regulating intestinal flora structure and arginine metabolism. J Neuroinflamm. 2023;20(1):122.","journal-title":"J Neuroinflamm"},{"issue":"1","key":"702_CR89","doi-asserted-by":"publisher","first-page":"104238","DOI":"10.4238\/gmr.15017522","volume":"15","author":"Y Wang","year":"2016","unstructured":"Wang Y, et al. All-trans retinoic acid prevents the development of type 1 diabetes by affecting the levels of interferon gamma and interleukin 4 in streptozotocin-induced murine diabetes model. Genet Mol Res. 2016;15(1):104238.","journal-title":"Genet Mol Res"},{"key":"702_CR90","doi-asserted-by":"crossref","unstructured":"Juang J-H et al. Prevention and reversal of diabetes by all-trans retinoid acid and exendin-4 in NOD mice. Int J Endocrinol. 2014;2014.","DOI":"10.1155\/2014\/435481"},{"issue":"6","key":"702_CR91","doi-asserted-by":"publisher","first-page":"9778","DOI":"10.1002\/jcp.27663","volume":"234","author":"S Khorasani","year":"2019","unstructured":"Khorasani S, et al. Amelioration of regulatory T cells by Lactobacillus delbrueckii and Lactobacillus rhamnosus in pristane-induced lupus mice model. J Cell Physiol. 2019;234(6):9778\u201386.","journal-title":"J Cell Physiol"},{"issue":"1","key":"702_CR92","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1002\/jcp.26819","volume":"234","author":"F Mardani","year":"2019","unstructured":"Mardani F, et al. In vivo study: Th1\u2013Th17 reduction in pristane-induced systemic lupus erythematosus mice after treatment with tolerogenic Lactobacillus probiotics. J Cell Physiol. 2019;234(1):642\u20139.","journal-title":"J Cell Physiol"},{"key":"702_CR93","doi-asserted-by":"publisher","first-page":"696074","DOI":"10.3389\/fimmu.2021.696074","volume":"12","author":"DS Kim","year":"2021","unstructured":"Kim DS, et al. Lactobacillus acidophilus supplementation exerts a synergistic effect on tacrolimus efficacy by modulating Th17\/Treg balance in lupus-prone mice via the SIGNR3 pathway. Front Immunol. 2021;12:696074.","journal-title":"Front Immunol"},{"issue":"4","key":"702_CR94","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1038\/nrmicro2540","volume":"9","author":"A Spor","year":"2011","unstructured":"Spor A, Koren O, Ley R. Unravelling the effects of the environment and host genotype on the gut microbiome. Nat Rev Microbiol. 2011;9(4):279\u201390.","journal-title":"Nat Rev Microbiol"},{"issue":"5883","key":"702_CR95","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1126\/science.1155725","volume":"320","author":"RE Ley","year":"2008","unstructured":"Ley RE, et al. Evolution of mammals and their gut microbes. Science. 2008;320(5883):1647\u201351.","journal-title":"Science"},{"issue":"6032","key":"702_CR96","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1126\/science.1198719","volume":"332","author":"BD Muegge","year":"2011","unstructured":"Muegge BD, et al. Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science. 2011;332(6032):970\u20134.","journal-title":"Science"},{"issue":"6","key":"702_CR97","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1111\/mec.12501","volume":"23","author":"F Delsuc","year":"2014","unstructured":"Delsuc F, et al. Convergence of gut microbiomes in myrmecophagous mammals. Mol Ecol. 2014;23(6):1301\u201317.","journal-title":"Mol Ecol"},{"issue":"7122","key":"702_CR98","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1038\/4441022a","volume":"444","author":"RE Ley","year":"2006","unstructured":"Ley RE, et al. Human gut microbes associated with obesity. Nature. 2006;444(7122):1022\u20133.","journal-title":"Nature"},{"issue":"2","key":"702_CR99","first-page":"1085","volume":"17","author":"MM Constantin","year":"2019","unstructured":"Constantin MM, et al. Significance and impact of dietary factors on systemic lupus erythematosus pathogenesis. Experimental Therapeutic Med. 2019;17(2):1085\u201390.","journal-title":"Experimental Therapeutic Med"},{"issue":"5","key":"702_CR100","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1016\/j.cell.2016.10.043","volume":"167","author":"MS Desai","year":"2016","unstructured":"Desai MS, et al. A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility. Cell. 2016;167(5):1339\u201353. e21.","journal-title":"Cell"},{"issue":"1","key":"702_CR101","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1038\/ni0111-5","volume":"12","author":"KM Maslowski","year":"2011","unstructured":"Maslowski KM, Mackay CR. Diet, gut microbiota and immune responses. Nat Immunol. 2011;12(1):5\u20139.","journal-title":"Nat Immunol"},{"issue":"1","key":"702_CR102","first-page":"6908677","volume":"2022","author":"PZ Putri","year":"2022","unstructured":"Putri PZ, Hamijoyo L, Sahiratmadja E. The role of diet in influencing the diversity of gut microbiome related to lupus disease activities: a systematic review. Int J Microbiol. 2022;2022(1):6908677.","journal-title":"Int J Microbiol"},{"issue":"1","key":"702_CR103","doi-asserted-by":"publisher","first-page":"24072","DOI":"10.1038\/srep24072","volume":"6","author":"P L\u00f3pez","year":"2016","unstructured":"L\u00f3pez P, et al. Th17 responses and natural IgM antibodies are related to gut microbiota composition in systemic lupus erythematosus patients. Sci Rep. 2016;6(1):24072.","journal-title":"Sci Rep"},{"key":"702_CR104","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2021\/9934533","volume":"2021","author":"MA Gerges","year":"2021","unstructured":"Gerges MA, et al. Altered profile of fecal microbiota in newly diagnosed systemic lupus erythematosus Egyptian patients. Int J Microbiol. 2021;2021:1\u20137.","journal-title":"Int J Microbiol"},{"issue":"7","key":"702_CR105","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1136\/annrheumdis-2018-214856","volume":"78","author":"D Azzouz","year":"2019","unstructured":"Azzouz D, et al. Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal. Ann Rheum Dis. 2019;78(7):947\u201356.","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"702_CR106","doi-asserted-by":"publisher","first-page":"01548","DOI":"10.1128\/mbio","volume":"5","author":"A Hevia","year":"2014","unstructured":"Hevia A, et al. Intestinal dysbiosis associated with systemic lupus erythematosus. MBio. 2014;5(5):01548\u201314. https:\/\/doi.org\/10.1128\/mbio","journal-title":"MBio"},{"issue":"48","key":"702_CR107","doi-asserted-by":"publisher","first-page":"p19745","DOI":"10.1073\/pnas.1211868109","volume":"109","author":"C Gr\u00f6nwall","year":"2012","unstructured":"Gr\u00f6nwall C, et al. MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses. Proc Natl Acad Sci. 2012;109(48):p19745\u201319750.","journal-title":"Proc Natl Acad Sci"},{"key":"702_CR108","doi-asserted-by":"publisher","first-page":"117157","DOI":"10.1016\/j.lfs.2019.117157","volume":"241","author":"SG Kirk","year":"2020","unstructured":"Kirk SG, Samavati L, Liu Y. MAP kinase phosphatase-1, a gatekeeper of the acute innate immune response. Life Sci. 2020;241:117157.","journal-title":"Life Sci"},{"issue":"10","key":"702_CR109","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.3390\/nu10101537","volume":"10","author":"Y Liu","year":"2018","unstructured":"Liu Y, Alookaran JJ, Rhoads JM. Probiotics in autoimmune and inflammatory disorders. Nutrients. 2018;10(10):1537.","journal-title":"Nutrients"},{"issue":"1","key":"702_CR110","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/s41467-017-02651-5","volume":"9","author":"R Fellows","year":"2018","unstructured":"Fellows R, et al. Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases. Nat Commun. 2018;9(1):105.","journal-title":"Nat Commun"},{"issue":"6","key":"702_CR111","doi-asserted-by":"publisher","first-page":"01358","DOI":"10.1128\/mbio","volume":"6","author":"C Gao","year":"2015","unstructured":"Gao C, et al. Histamine H2 receptor-mediated suppression of intestinal inflammation by probiotic Lactobacillus reuteri. MBio. 2015;6(6):01358\u201315. https:\/\/doi.org\/10.1128\/mbio","journal-title":"MBio"},{"key":"702_CR112","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s12223-017-0524-9","volume":"62","author":"G Greifov\u00e1","year":"2017","unstructured":"Greifov\u00e1 G, et al. Analysis of antimicrobial and immunomodulatory substances produced by heterofermentative Lactobacillus reuteri. Folia Microbiol. 2017;62:515\u201324.","journal-title":"Folia Microbiol"},{"issue":"8","key":"702_CR113","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1136\/gut.2010.232918","volume":"60","author":"EM Fernandez","year":"2011","unstructured":"Fernandez EM, et al. Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide. Gut. 2011;60(8):1050\u20139.","journal-title":"Gut"},{"issue":"5","key":"702_CR114","doi-asserted-by":"publisher","first-page":"e10632","DOI":"10.1371\/journal.pone.0010632","volume":"5","author":"M Meijerink","year":"2010","unstructured":"Meijerink M, et al. Identification of genetic loci in Lactobacillus plantarum that modulate the immune response of dendritic cells using comparative genome hybridization. PLoS ONE. 2010;5(5):e10632.","journal-title":"PLoS ONE"},{"issue":"2","key":"702_CR115","doi-asserted-by":"publisher","first-page":"151","DOI":"10.2217\/imt.11.163","volume":"4","author":"MW Khan","year":"2012","unstructured":"Khan MW, et al. Modulating intestinal immune responses by lipoteichoic acid-deficient Lactobacillus acidophilus. Immunotherapy. 2012;4(2):151\u201361.","journal-title":"Immunotherapy"},{"issue":"3","key":"702_CR116","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1016\/j.jaci.2014.04.034","volume":"134","author":"R Ferstl","year":"2014","unstructured":"Ferstl R, et al. Histamine receptor 2 is a key influence in immune responses to intestinal histamine-secreting microbes. J Allergy Clin Immunol. 2014;134(3):744\u20136. e3.","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"702_CR117","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.jaci.2013.01.013","volume":"132","author":"R Frei","year":"2013","unstructured":"Frei R, et al. Histamine receptor 2 modifies dendritic cell responses to microbial ligands. J Allergy Clin Immunol. 2013;132(1):194\u2013204. e12.","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"702_CR118","doi-asserted-by":"publisher","first-page":"2242","DOI":"10.1172\/JCI44031","volume":"121","author":"F Yan","year":"2011","unstructured":"Yan F, et al. Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. J Clin Investig. 2011;121(6):2242\u201353.","journal-title":"J Clin Investig"},{"issue":"3","key":"702_CR119","doi-asserted-by":"publisher","first-page":"e17495","DOI":"10.1371\/journal.pone.0017495","volume":"6","author":"S Sule","year":"2011","unstructured":"Sule S, et al. Abnormal production of pro-and anti-inflammatory cytokines by lupus monocytes in response to apoptotic cells. PLoS ONE. 2011;6(3):e17495.","journal-title":"PLoS ONE"},{"issue":"1","key":"702_CR120","first-page":"4","volume":"1","author":"EJ Fattahi","year":"2023","unstructured":"Fattahi EJ, Nouruzi V, Mahboobi L. The levels of mRNA for pro-and anti-inflammatory cytokines and B cell amounts in patients with lupus erythematosus. Biomed Res. 2023;1(1):4.","journal-title":"Biomed Res"},{"issue":"12","key":"702_CR121","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1093\/intimm\/dxm103","volume":"19","author":"LN Fink","year":"2007","unstructured":"Fink LN, et al. Distinct gut-derived lactic acid bacteria elicit divergent dendritic cell-mediated NK cell responses. Int Immunol. 2007;19(12):1319\u201327.","journal-title":"Int Immunol"},{"issue":"4","key":"702_CR122","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1189\/jlb.0611286","volume":"92","author":"D Ghadimi","year":"2012","unstructured":"Ghadimi D, et al. Epigenetic imprinting by commensal probiotics inhibits the IL-23\/IL-17 axis in an in vitro model of the intestinal mucosal immune system. J Leukoc Biol. 2012;92(4):895\u2013911.","journal-title":"J Leukoc Biol"},{"issue":"2","key":"702_CR123","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1111\/j.1365-2249.2010.04173.x","volume":"161","author":"H Dong","year":"2010","unstructured":"Dong H, et al. Selective effects of Lactobacillus casei Shirota on T cell activation, natural killer cell activity and cytokine production. Clin Experimental Immunol. 2010;161(2):378\u201388.","journal-title":"Clin Experimental Immunol"},{"issue":"6","key":"702_CR124","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1080\/19490976.2020.1768644","volume":"11","author":"M Guo","year":"2020","unstructured":"Guo M, et al. Alteration in gut microbiota is associated with dysregulation of cytokines and glucocorticoid therapy in systemic lupus erythematosus. Gut Microbes. 2020;11(6):1758\u201373.","journal-title":"Gut Microbes"},{"key":"702_CR125","doi-asserted-by":"publisher","first-page":"1040211","DOI":"10.3389\/fcimb.2022.1040211","volume":"12","author":"H Yao","year":"2022","unstructured":"Yao H, et al. Gut microbiome and fecal metabolic alteration in systemic lupus erythematosus patients with depression. Front Cell Infect Microbiol. 2022;12:1040211.","journal-title":"Front Cell Infect Microbiol"},{"issue":"6","key":"702_CR126","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1016\/j.jaci.2005.03.036","volume":"115","author":"HH Smits","year":"2005","unstructured":"Smits HH, et al. Selective probiotic bacteria induce IL-10\u2013producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell\u2013specific intercellular adhesion molecule 3\u2013grabbing nonintegrin. J Allergy Clin Immunol. 2005;115(6):1260\u20137.","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"702_CR127","doi-asserted-by":"publisher","first-page":"e0120261","DOI":"10.1371\/journal.pone.0120261","volume":"10","author":"P Konieczna","year":"2015","unstructured":"Konieczna P, et al. Human dendritic cell DC-SIGN and TLR-2 mediate complementary immune regulatory activities in response to Lactobacillus rhamnosus JB-1. PLoS ONE. 2015;10(3):e0120261.","journal-title":"PLoS ONE"},{"issue":"5","key":"702_CR128","doi-asserted-by":"publisher","first-page":"e1002714","DOI":"10.1371\/journal.ppat.1002714","volume":"8","author":"SG Jeon","year":"2012","unstructured":"Jeon SG, et al. Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon. PLoS Pathog. 2012;8(5):e1002714.","journal-title":"PLoS Pathog"},{"issue":"6032","key":"702_CR129","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1126\/science.1206095","volume":"332","author":"JL Round","year":"2011","unstructured":"Round JL, et al. The toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science. 2011;332(6032):974\u20137.","journal-title":"Science"},{"issue":"2","key":"702_CR130","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/j.1365-2249.2011.04496.x","volume":"167","author":"O Donkor","year":"2012","unstructured":"Donkor O, et al. Cytokine profile and induction of T helper type 17 and regulatory T cells by human peripheral mononuclear cells after microbial exposure. Clin Experimental Immunol. 2012;167(2):282\u201395.","journal-title":"Clin Experimental Immunol"},{"key":"702_CR131","unstructured":"Pizano JM et al. Probiotics and disease: a comprehensive summary\u2014part 7, immune disorders. Integrative Medicine: a Clinician\u2019s Journal. 2017;16(5):46."},{"key":"702_CR132","doi-asserted-by":"publisher","first-page":"875788","DOI":"10.3389\/fimmu.2022.875788","volume":"13","author":"L Sapra","year":"2022","unstructured":"Sapra L, et al. Bifidobacterium longum ameliorates ovariectomy-induced bone loss via enhancing anti-osteoclastogenic and immunomodulatory potential of regulatory B cells (Bregs). Front Immunol. 2022;13:875788.","journal-title":"Front Immunol"},{"issue":"2","key":"702_CR133","doi-asserted-by":"publisher","first-page":"2247053","DOI":"10.1080\/19490976.2023.2247053","volume":"15","author":"J Mole\u00f3n","year":"2023","unstructured":"Mole\u00f3n J, et al. Targeting the gut microbiota with dietary fibers: a novel approach to prevent the development cardiovascular complications linked to systemic lupus erythematosus in a preclinical study. Gut Microbes. 2023;15(2):2247053.","journal-title":"Gut Microbes"},{"key":"702_CR134","doi-asserted-by":"publisher","first-page":"686501","DOI":"10.3389\/fimmu.2021.686501","volume":"12","author":"L Zhang","year":"2021","unstructured":"Zhang L, et al. Gut microbiome and metabolites in systemic lupus erythematosus: link, mechanisms and intervention. Front Immunol. 2021;12:686501.","journal-title":"Front Immunol"},{"issue":"11","key":"702_CR135","doi-asserted-by":"publisher","first-page":"2676","DOI":"10.3390\/nu11112676","volume":"11","author":"N de la Visitaci\u00f3n","year":"2019","unstructured":"de la Visitaci\u00f3n N, et al. Protective effects of probiotic consumption in cardiovascular disease in systemic lupus erythematosus. Nutrients. 2019;11(11):2676.","journal-title":"Nutrients"},{"key":"702_CR136","doi-asserted-by":"publisher","first-page":"421934","DOI":"10.3389\/fimmu.2018.02838","volume":"9","author":"C Martin-Gallausiaux","year":"2018","unstructured":"Martin-Gallausiaux C, et al. Butyrate produced by commensal bacteria down-regulates indolamine 2, 3-dioxygenase 1 (IDO-1) expression via a dual mechanism in human intestinal epithelial cells. Front Immunol. 2018;9:421934.","journal-title":"Front Immunol"},{"key":"702_CR137","doi-asserted-by":"crossref","unstructured":"Toral M et al. Lactobacillus fermentum CECT5716: a novel alternative for the prevention of vascular disorders in a mouse model of systemic lupus erythematosus. FASEB J 2019;33(9):10005\u201310018.","DOI":"10.1096\/fj.201900545RR"},{"issue":"12","key":"702_CR138","doi-asserted-by":"publisher","first-page":"1998","DOI":"10.1016\/j.jand.2020.08.076","volume":"120","author":"J Morze","year":"2020","unstructured":"Morze J, et al. Diet quality as assessed by the healthy eating index, alternate healthy eating index, dietary approaches to stop hypertension score, and health outcomes: a second update of a systematic review and meta-analysis of cohort studies. J Acad Nutr Dietetics. 2020;120(12):1998\u20132031. e15.","journal-title":"J Acad Nutr Dietetics"},{"issue":"4","key":"702_CR139","doi-asserted-by":"publisher","first-page":"439","DOI":"10.3390\/nu10040439","volume":"10","author":"S Carlos","year":"2018","unstructured":"Carlos S, et al. Mediterranean diet and health outcomes in the SUN cohort. Nutrients. 2018;10(4):439.","journal-title":"Nutrients"},{"key":"702_CR140","doi-asserted-by":"publisher","first-page":"757","DOI":"10.3389\/fmicb.2018.00757","volume":"9","author":"Q Mu","year":"2018","unstructured":"Mu Q, Tavella VJ, Luo XM. Role of Lactobacillus reuteri in human health and diseases. Front Microbiol. 2018;9:757.","journal-title":"Front Microbiol"},{"issue":"4","key":"702_CR141","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/cmi.2016.64","volume":"14","author":"Y Shi","year":"2017","unstructured":"Shi Y, Mu L. An expanding stage for commensal microbes in host immune regulation. Cell Mol Immunol. 2017;14(4):339\u201348.","journal-title":"Cell Mol Immunol"},{"issue":"3","key":"702_CR142","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/mi.2013.13","volume":"6","author":"M Fukata","year":"2013","unstructured":"Fukata M, Arditi M. The role of pattern recognition receptors in intestinal inflammation. Mucosal Immunol. 2013;6(3):451\u201363.","journal-title":"Mucosal Immunol"},{"issue":"9","key":"702_CR143","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/j.it.2009.06.003","volume":"30","author":"WH Reeves","year":"2009","unstructured":"Reeves WH, et al. Induction of autoimmunity by pristane and other naturally occurring hydrocarbons. Trends Immunol. 2009;30(9):455\u201364.","journal-title":"Trends Immunol"},{"issue":"4","key":"702_CR144","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1177\/0300985810370005","volume":"47","author":"J Rottman","year":"2010","unstructured":"Rottman J, Willis C. Mouse models of systemic lupus erythematosus reveal a complex pathogenesis. Vet Pathol. 2010;47(4):664\u201376.","journal-title":"Vet Pathol"},{"issue":"1","key":"702_CR145","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1515\/jcim-2012-0054","volume":"10","author":"\u00d6 \u00d6zdemir","year":"2013","unstructured":"\u00d6zdemir \u00d6. Any role for probiotics in the therapy or prevention of autoimmune diseases? Up-to-date review. J Complement Integr Med. 2013;10(1):229\u201350.","journal-title":"J Complement Integr Med"},{"key":"702_CR146","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1007\/s12602-020-09668-1","volume":"13","author":"Y-L Yeh","year":"2021","unstructured":"Yeh Y-L, et al. Heat-killed Lactobacillus reuteri GMNL-263 inhibits systemic lupus erythematosus\u2013induced cardiomyopathy in NZB\/W F1 mice. Probiotics Antimicrob Proteins. 2021;13:51\u20139.","journal-title":"Probiotics Antimicrob Proteins"},{"key":"702_CR147","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40168-017-0300-8","volume":"5","author":"Q Mu","year":"2017","unstructured":"Mu Q, et al. Control of lupus nephritis by changes of gut microbiota. Microbiome. 2017;5:1\u201312.","journal-title":"Microbiome"},{"issue":"6","key":"702_CR148","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1080\/08916934.2020.1777282","volume":"53","author":"JN Manirarora","year":"2020","unstructured":"Manirarora JN, Kosiewicz MM, Alard P. Feeding lactobacilli impacts lupus progression in (NZBxNZW) F1 lupus-prone mice by enhancing immunoregulation. Autoimmunity. 2020;53(6):323\u201332.","journal-title":"Autoimmunity"},{"issue":"9","key":"702_CR149","doi-asserted-by":"publisher","first-page":"10005","DOI":"10.1096\/fj.201900545RR","volume":"33","author":"M Toral","year":"2019","unstructured":"Toral M, et al. Lactobacillus fermentum CECT5716: a novel alternative for the prevention of vascular disorders in a mouse model of systemic lupus erythematosus. FASEB J. 2019;33(9):10005\u201318.","journal-title":"FASEB J"},{"issue":"8","key":"702_CR150","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1017\/S0007114517001039","volume":"117","author":"T-C Hsu","year":"2017","unstructured":"Hsu T-C, et al. Lactobacillus paracasei GMNL-32, Lactobacillus reuteri GMNL-89 and L. reuteri GMNL-263 ameliorate hepatic injuries in lupus-prone mice. Br J Nutr. 2017;117(8):1066\u201374.","journal-title":"Br J Nutr"},{"issue":"9","key":"702_CR151","doi-asserted-by":"publisher","first-page":"e0185098","DOI":"10.1371\/journal.pone.0185098","volume":"12","author":"W-S Hu","year":"2017","unstructured":"Hu W-S, et al. Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in NZB\/W F1 mice. PLoS ONE. 2017;12(9):e0185098.","journal-title":"PLoS ONE"},{"issue":"2","key":"702_CR152","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1046\/j.1365-2249.1999.00951.x","volume":"117","author":"A Mike","year":"1999","unstructured":"Mike A, et al. Prevention of B220\u2009+\u2009T cell expansion and prolongation of lifespan induced by Lactobacillus casei in MRL\/lpr mice. Clin Experimental Immunol. 1999;117(2):368\u201375.","journal-title":"Clin Experimental Immunol"},{"issue":"5","key":"702_CR153","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1017\/S0007114517002112","volume":"118","author":"B-S Tzang","year":"2017","unstructured":"Tzang B-S, et al. Effects of oral Lactobacillus administration on antioxidant activities and CD4\u2009+\u2009CD25\u2009+\u2009forkhead box P3 (FoxP3)\u2009+\u2009T cells in NZB\/W F1 mice. Br J Nutr. 2017;118(5):333\u201342.","journal-title":"Br J Nutr"},{"key":"702_CR154","doi-asserted-by":"publisher","first-page":"923754","DOI":"10.3389\/fimmu.2022.923754","volume":"13","author":"X Cabana-Puig","year":"2022","unstructured":"Cabana-Puig X, et al. Lactobacillus spp. Act in synergy to attenuate splenomegaly and lymphadenopathy in lupus-prone MRL\/lpr mice. Front Immunol. 2022;13:923754.","journal-title":"Front Immunol"},{"key":"702_CR155","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s12602-017-9264-z","volume":"9","author":"HA Seddik","year":"2017","unstructured":"Seddik HA, et al. Lactobacillus plantarum and its probiotic and food potentialities. Probiotics Antimicrob Proteins. 2017;9:111\u201322.","journal-title":"Probiotics Antimicrob Proteins"},{"key":"702_CR156","doi-asserted-by":"crossref","unstructured":"Cheng L, et al. Effects of Lactobacillus plantarum HFY15 on lupus nephritis in mice by regulation of the TGF-\u03b21 signaling pathway. Drug Design, Development and Therapy; 2022. pp. 2851\u201360.","DOI":"10.2147\/DDDT.S363974"},{"key":"702_CR157","doi-asserted-by":"publisher","first-page":"173421","DOI":"10.1016\/j.ejphar.2020.173421","volume":"884","author":"D Li","year":"2020","unstructured":"Li D, et al. Bacteroides fragilis alleviates the symptoms of lupus nephritis via regulating CD1d and CD86 expressions in B cells. Eur J Pharmacol. 2020;884:173421.","journal-title":"Eur J Pharmacol"},{"key":"702_CR158","doi-asserted-by":"crossref","unstructured":"Kim JiYeun KJ, Park PM, MyeongSoo, Ji JG, GeunEog. Probiotic modulation of dendritic cells co-cultured with intestinal epithelial cells. World J Gastroenterol 2012;18(12):1308\u201318.","DOI":"10.3748\/wjg.v18.i12.1308"},{"issue":"2","key":"702_CR159","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.immuni.2013.08.003","volume":"39","author":"T Zelante","year":"2013","unstructured":"Zelante T, et al. Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22. Immunity. 2013;39(2):372\u201385.","journal-title":"Immunity"},{"key":"702_CR160","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.3389\/fimmu.2018.01546","volume":"9","author":"IS Ludwig","year":"2018","unstructured":"Ludwig IS, et al. Lactobacillus rhamnosus GG-derived soluble mediators modulate adaptive immune cells. Front Immunol. 2018;9:1546.","journal-title":"Front Immunol"},{"key":"702_CR161","doi-asserted-by":"crossref","unstructured":"Dolpady J et al. Oral probiotic VSL# 3 prevents autoimmune diabetes by modulating microbiota and promoting indoleamine 2, 3-dioxygenase-enriched tolerogenic intestinal environment. J Diabetes Res. 2016;2016.","DOI":"10.1155\/2016\/7569431"},{"issue":"5","key":"702_CR162","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1002\/ibd.20369","volume":"14","author":"A Pronio","year":"2008","unstructured":"Pronio A, et al. Probiotic administration in patients with ileal pouch\u2013anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells. Inflamm Bowel Dis. 2008;14(5):662\u20138.","journal-title":"Inflamm Bowel Dis"},{"issue":"3","key":"702_CR163","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1053\/j.gastro.2004.11.050","volume":"128","author":"L O\u2019Mahony","year":"2005","unstructured":"O\u2019Mahony L, et al. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology. 2005;128(3):541\u201351.","journal-title":"Gastroenterology"},{"issue":"21","key":"702_CR164","doi-asserted-by":"publisher","first-page":"3419","DOI":"10.3390\/cells11213419","volume":"11","author":"A Widhani","year":"2022","unstructured":"Widhani A, et al. Changes in gut microbiota and systemic inflammation after synbiotic supplementation in patients with systemic lupus erythematosus: a randomized, double-blind, placebo-controlled trial. Cells. 2022;11(21):3419.","journal-title":"Cells"},{"issue":"6","key":"702_CR165","first-page":"715","volume":"13","author":"K Meijer","year":"2010","unstructured":"Meijer K, de Vos P, Priebe MG. Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health? Curr Opin Clin Nutr Metabolic Care. 2010;13(6):715\u201321.","journal-title":"Curr Opin Clin Nutr Metabolic Care"},{"issue":"4","key":"702_CR166","doi-asserted-by":"publisher","first-page":"642","DOI":"10.46497\/ArchRheumatol.2023.9941","volume":"38","author":"A Alaei","year":"2023","unstructured":"Alaei A, et al. The effects of Lactobacillus delbrueckii and Lactobacillus rhamnosus on cytokines and their related molecules: an ex vivo study on patients with systemic lupus erythematosus. Archives Rheumatol. 2023;38(4):642.","journal-title":"Archives Rheumatol"},{"issue":"1","key":"702_CR167","doi-asserted-by":"publisher","first-page":"e85923","DOI":"10.1371\/journal.pone.0085923","volume":"9","author":"C Santos Rocha","year":"2014","unstructured":"Santos Rocha C, et al. Local and systemic immune mechanisms underlying the anti-colitis effects of the dairy bacterium Lactobacillus delbrueckii. PLoS ONE. 2014;9(1):e85923.","journal-title":"PLoS ONE"},{"issue":"4","key":"702_CR168","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1002\/ibd.21834","volume":"18","author":"C Santos Rocha","year":"2012","unstructured":"Santos Rocha C, et al. Anti-inflammatory properties of dairy lactobacilli. Inflamm Bowel Dis. 2012;18(4):657\u201366.","journal-title":"Inflamm Bowel Dis"},{"issue":"9","key":"702_CR169","doi-asserted-by":"publisher","first-page":"7865","DOI":"10.1002\/jcb.27203","volume":"119","author":"SA Esmaeili","year":"2018","unstructured":"Esmaeili SA, et al. Generation of tolerogenic dendritic cells using Lactobacillus rhamnosus and Lactobacillus delbrueckii as tolerogenic probiotics. J Cell Biochem. 2018;119(9):7865\u201372.","journal-title":"J Cell Biochem"},{"issue":"3","key":"702_CR170","doi-asserted-by":"publisher","first-page":"261","DOI":"10.4161\/gmic.20358","volume":"3","author":"P Konieczna","year":"2012","unstructured":"Konieczna P, et al. Portrait of an immunoregulatory Bifidobacterium. Gut Microbes. 2012;3(3):261\u20136.","journal-title":"Gut Microbes"},{"issue":"2","key":"702_CR171","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3390\/nu15020269","volume":"15","author":"A Rousseaux","year":"2023","unstructured":"Rousseaux A, Brosseau C, Bodinier M. Immunomodulation of B lymphocytes by prebiotics, probiotics and synbiotics: application in pathologies. Nutrients. 2023;15(2):269.","journal-title":"Nutrients"},{"issue":"4","key":"702_CR172","doi-asserted-by":"publisher","first-page":"e00070","DOI":"10.1128\/msphere.00070-23","volume":"8","author":"M Guo","year":"2023","unstructured":"Guo M, et al. Akkermansia muciniphila and Lactobacillus plantarum ameliorate systemic lupus erythematosus by possibly regulating immune response and remodeling gut microbiota. Msphere. 2023;8(4):e00070\u201323.","journal-title":"Msphere"},{"key":"702_CR173","doi-asserted-by":"publisher","first-page":"626217","DOI":"10.3389\/fimmu.2021.626217","volume":"12","author":"F Liu","year":"2021","unstructured":"Liu F, et al. Distinct microbiomes of gut and saliva in patients with systemic lupus erythematous and clinical associations. Front Immunol. 2021;12:626217.","journal-title":"Front Immunol"},{"issue":"6","key":"702_CR174","doi-asserted-by":"publisher","first-page":"e0199018","DOI":"10.1371\/journal.pone.0199018","volume":"13","author":"S Arai","year":"2018","unstructured":"Arai S, et al. Orally administered heat-killed Lactobacillus paracasei MCC1849 enhances antigen-specific IgA secretion and induces follicular helper T cells in mice. PLoS ONE. 2018;13(6):e0199018.","journal-title":"PLoS ONE"},{"issue":"8","key":"702_CR175","doi-asserted-by":"publisher","first-page":"2669","DOI":"10.3390\/nu13082669","volume":"13","author":"N de la Visitaci\u00f3n","year":"2021","unstructured":"de la Visitaci\u00f3n N, et al. Probiotics prevent hypertension in a murine model of systemic lupus erythematosus induced by toll-like receptor 7 activation. Nutrients. 2021;13(8):2669.","journal-title":"Nutrients"},{"key":"702_CR176","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.jff.2018.07.025","volume":"48","author":"Z Vahidi","year":"2018","unstructured":"Vahidi Z, et al. Lactobacillus rhamnosus and Lactobacillus delbrueckii ameliorate the expression of miR-155 and miR-181a in SLE patients. J Funct Foods. 2018;48:228\u201333.","journal-title":"J Funct Foods"},{"issue":"11","key":"702_CR177","first-page":"1509","volume":"24","author":"S-A Esmaeili","year":"2021","unstructured":"Esmaeili S-A, et al. Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs. Iran J Basic Med Sci. 2021;24(11):1509.","journal-title":"Iran J Basic Med Sci"},{"key":"702_CR178","doi-asserted-by":"publisher","first-page":"102844","DOI":"10.1016\/j.jaut.2022.102844","volume":"130","author":"C Huang","year":"2022","unstructured":"Huang C, et al. Safety and efficacy of fecal microbiota transplantation for treatment of systemic lupus erythematosus: an EXPLORER trial. J Autoimmun. 2022;130:102844.","journal-title":"J Autoimmun"},{"issue":"2","key":"702_CR179","doi-asserted-by":"publisher","first-page":"543","DOI":"10.4103\/mmj.mmj_55_22","volume":"35","author":"A Shaaban","year":"2022","unstructured":"Shaaban A, et al. Gut lactobacilli profile among a cohort of Egyptian patients with systemic lupus erythematosus. Menoufia Med J. 2022;35(2):543.","journal-title":"Menoufia Med J"}],"container-title":["Gut Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13099-025-00702-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13099-025-00702-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13099-025-00702-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T22:05:13Z","timestamp":1757196313000},"score":1,"resource":{"primary":{"URL":"https:\/\/gutpathogens.biomedcentral.com\/articles\/10.1186\/s13099-025-00702-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,17]]},"references-count":179,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["702"],"URL":"https:\/\/doi.org\/10.1186\/s13099-025-00702-7","relation":{},"ISSN":["1757-4749"],"issn-type":[{"value":"1757-4749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,17]]},"assertion":[{"value":"15 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2025","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The Funding information was updated.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"45"}}