{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:07:10Z","timestamp":1792688830366,"version":"4.5.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,17]],"date-time":"2019-10-17T00:00:00Z","timestamp":1571270400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,10,17]],"date-time":"2019-10-17T00:00:00Z","timestamp":1571270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n              <jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>The investigation and management of celiac disease places a high burden on the health care system. Accurate methods to ascertain cases of celiac disease (CD) in population-based administrative data can facilitate epidemiologic and health services research to guide disease management. The study aim was to develop and validate administrative data case definitions for CD to facilitate further studies about the effect of CD on osteoporosis and fracture risk.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Population-based data from the Manitoba Bone Mineral Density (BMD) Program registry, which contains medical information on all individuals in the province of Manitoba, Canada who have received BMD testing, was used to define the study cohort. Linked hospital discharge abstracts and physician billing claims were used to ascertain diagnoses of celiac disease in administrative data. A population-based CD serologic registry was used as the validation database. One diagnosis code in hospital discharge abstracts or two or more diagnosis codes in physician billing claims optimized the detection of positive celiac serology with sensitivity of 84% (95% CI 80\u201388%), specificity of 97% (95% CI 80\u201388%), PPV of 80% (95% CI 80\u201388%), and NPV of 97% (95% CI 80\u201388%). Our administrative data case definition for celiac disease demonstrates good sensitivity and specificity for detecting positive celiac serology.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13104-019-4693-2","type":"journal-article","created":{"date-parts":[[2019,10,17]],"date-time":"2019-10-17T13:10:08Z","timestamp":1571317808000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Development of an administrative definition for celiac disease"],"prefix":"10.1186","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6744-2722","authenticated-orcid":false,"given":"Donald R.","family":"Duerksen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa M.","family":"Lix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William D.","family":"Leslie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,10,17]]},"reference":[{"key":"4693_CR1","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/S0140-6736(17)31796-8","volume":"391","author":"B Lebwohl","year":"2018","unstructured":"Lebwohl B, Sanders DS, Green PHR. Coeliac disease. Lancet. 2018;391:70\u201381.","journal-title":"Lancet"},{"issue":"7","key":"4693_CR2","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1001\/jama.2017.9730","volume":"318","author":"MM Leonard","year":"2017","unstructured":"Leonard MM, Sapone A, Catassi C, Fasano A. Celiac disease and nonceliac gluten sensitivity: a review. JAMA. 2017;318(7):647\u201356.","journal-title":"JAMA"},{"issue":"10","key":"4693_CR3","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1093\/oxfordjournals.aje.a009735","volume":"149","author":"CN Bernstein","year":"1999","unstructured":"Bernstein CN, Blanchard JF, Rawsthorne P, Wajda A. Epidemiology of Crohn\u2019s disease and ulcerative colitis in a central Canadian province: a population-based study. 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Data access was approved by the Health Information Privacy Committee. Consent to participate was not required as all data has been anonymized.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"661"}}