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Therefore, this study evaluated the contribution of the N<jats:sub>2<\/jats:sub>SBW test to the detection of pulmonary involvement in patients with rheumatoid arthritis (RA).<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Twenty-one patients with RA underwent clinical evaluation, pulmonary function tests (PFTs), including the N2<jats:sub>S<\/jats:sub>BW test, and computed tomography (CT). The main tomographic findings were air trapping and bronchiectasis (57.1% and 23.8% of cases, respectively). According to the phase III slope of the N<jats:sub>2<\/jats:sub>SBW (phase III slope), 11 and 10 patients had values &lt;\u2009120% predicted and &gt;\u2009120% predicted, respectively. Five patients with limited involvement on CT had a phase III slope\u2009&gt;\u2009120%. The residual volume\/total lung capacity ratio was significantly different between patients with phase III slopes\u2009&lt;\u2009120% and &gt;\u2009120% (<jats:italic>P\u2009<\/jats:italic>=\u20090.024). Additionally, rheumatoid factor positivity was higher in patients with a phase III slope\u2009&gt;\u2009120% (<jats:italic>P\u2009<\/jats:italic>=\u20090.021). In patients with RA and airway disease on CT, the N<jats:sub>2<\/jats:sub>SBW test detects inhomogeneity in the ventilation distribution in approximately half of the cases, even in those with normal conventional PFT results.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13104-019-4767-1","type":"journal-article","created":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T09:04:41Z","timestamp":1573117481000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Does the nitrogen single-breath washout test contribute to detecting pulmonary involvement in rheumatoid arthritis? 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