{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:28:42Z","timestamp":1772166522497,"version":"3.50.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,12,26]],"date-time":"2019-12-26T00:00:00Z","timestamp":1577318400000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purpose of the research is to test the measurement of the total urinary volume, induced by the diuretic osmotic action of mannitol, in a group of symptomatic MD patients and in healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>An altered excretory urinary volume after mannitol challenge was observed in symptomatic MD (874.3\u2009\u00b1\u2009302.1) compared to healthy volunteers (361.7\u2009\u00b1\u2009181.6) (p\u2009=\u20090.0001). This easy and self-administered method might be proposed to replace the analysis of the urinary sugars\u2019 concentration in symptomatic MD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13104-019-4870-3","type":"journal-article","created":{"date-parts":[[2019,12,26]],"date-time":"2019-12-26T13:02:44Z","timestamp":1577365364000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Increased urinary volumes in symptomatic M\u00e9ni\u00e8re\u2019s Disease"],"prefix":"10.1186","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7514-5624","authenticated-orcid":false,"given":"Federica","family":"Di Berardino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Zanetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,26]]},"reference":[{"key":"4870_CR1","doi-asserted-by":"publisher","first-page":"2179","DOI":"10.1001\/jama.1923.02650260021006","volume":"81","author":"W Duke","year":"1923","unstructured":"Duke W. 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The work was carried out in accordance with the Helsinki Declaration of 1975, as revised in 2008, including, but not limited to, the absence of potential harm to participants, their guaranteed anonymity, and informed consent approved by the Ethics Committee of Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico of Milan, Italy. All the participants have provided a signed written consent to participate.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors and the participants provided consent for publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"826"}}