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This study aimed at determining microbial load, prevalence and antimicrobial resistance profiles of\n                      <jats:italic>Salmonella<\/jats:italic>\n                      sp. and\n                      <jats:italic>E. coli<\/jats:italic>\n                      and associated resistance genes among isolates from poultry feeds.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 150 samples of different poultry feed types were randomly collected from selected sites within Ruiru Sub-County. The microbial load was determined,\n                      <jats:italic>Salmonella<\/jats:italic>\n                      sp. and\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      were isolated and antimicrobial susceptibility test carried out. Antimicrobial resistance genes were also screened among the resistant isolates. Out of analyzed samples, 58% and 28% contained\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      and\n                      <jats:italic>Salmonella<\/jats:italic>\n                      sp. respectively. Bacterial load ranged between 3.1\u2009\u00d7\u200910\n                      <jats:sup>5<\/jats:sup>\n                      and 3.0\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      \u00a0cfu\/g. Highest resistance was against ampicillin (41%) for\n                      <jats:italic>Salmonella<\/jats:italic>\n                      sp. and (62%) for\n                      <jats:italic>E. coli<\/jats:italic>\n                      isolates. Ampicillin resistant isolates carried\n                      <jats:italic>TEM<\/jats:italic>\n                      and\n                      <jats:italic>SHV<\/jats:italic>\n                      genes. In addition,\n                      <jats:italic>strB<\/jats:italic>\n                      and\n                      <jats:italic>Dfr<\/jats:italic>\n                      resistance genes associated with streptomycin and cotri-moxazole were detected. All the isolates were susceptible to chloramphenicol and ciprofloxacin. The study reveals high bacterial contamination, presence of beta-lactamase, aminoglycoside and sulphonamide resistance genes across isolates from poultry feeds. Therefore, contaminated poultry feeds with bacteria are likely to lead to increase in antimicrobial resistant strains across the community.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13104-021-05456-4","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T21:24:41Z","timestamp":1612214681000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Prevalence and antimicrobial resistance profiles of Salmonella species and Escherichia coli isolates from poultry feeds in Ruiru Sub-County, Kenya"],"prefix":"10.1186","volume":"14","author":[{"given":"Dorica Gakii","family":"Ngai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony Kebira","family":"Nyamache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omwoyo","family":"Ombori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"issue":"5","key":"5456_CR1","first-page":"495","volume":"3","author":"ML Al-Musawi","year":"2016","unstructured":"Al-Musawi ML, Hussein SB, Gatoof MJ, Hanash NA, Abdulkareem BZ. 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Poultry feeds were bought from the outlets. The study was approved by the Kenya National Commission for Science, Technology and Innovation and authorization given by County Commissioner, Kiambu County Kenya.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"41"}}