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Of seven IgG and IgM positive samples, five and two samples were high and low in IgG avidity, respectively. Based on PCR analysis, <jats:italic>Toxoplasma<\/jats:italic> infection was detected in one sample with anti-<jats:italic>T. gondii<\/jats:italic> IgM and low IgG avidity. The Chi-square test showed significant correlations of <jats:italic>T. gondii<\/jats:italic> seropositivity with history of undercooked meat consumption and contacts with cats (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). In the present study, 79.75% of the participants were negative for IgG against <jats:italic>T. gondii<\/jats:italic> infection. Furthermore, recently acquired <jats:italic>Toxoplasma<\/jats:italic> infection was found using IgG avidity and PCR assays among women of childbearing-age in the study area, which would increase the risk of their fetus becoming infected. Educational program and antenatal screening of childbearing-age women for <jats:italic>T. gondii<\/jats:italic> infection may be important primary prevention strategies and help reduce the risk of congenital toxoplasmosis in this population.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13104-021-05581-0","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T09:03:19Z","timestamp":1619773399000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Seroepidemiological study of toxoplasmosis in women referred to a pre-marriage counseling center in Alborz Province, Iran"],"prefix":"10.1186","volume":"14","author":[{"given":"Melica","family":"Shahighi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliehsan","family":"Heidari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Keshavarz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Bairami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeedeh","family":"Shojaee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monireh","family":"Sezavar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahboobeh","family":"Salimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aref","family":"Teimouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"issue":"12\u201313","key":"5581_CR1","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1016\/S0020-7519(00)00124-7","volume":"30","author":"AM Tenter","year":"2000","unstructured":"Tenter AM, Heckeroth AR, Weiss LM. 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The current study was approved by the Research Ethical Review Committee of Alborz University of Medical Sciences, Karaj, Iran (approval no. Abzums.Rec1395.26). All participants agreed that their participation was voluntary and were informed that the methodology included no potential risks and that their information was assumed strictly confidential. Informed written consents were signed by all the participants before the study commencement. For the participants under the age of 16\u00a0years, parental consents were signed by their parents or guardians.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that we do not have any competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"163"}}