{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:59:39Z","timestamp":1790402379478,"version":"4.1.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T00:00:00Z","timestamp":1644796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T00:00:00Z","timestamp":1644796800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>Abnormal thyroid function may disrupt sleep architecture. We aimed to determine the frequency of various chronotypes in women with hypothyroidism. We performed a single-center retrospective study at an ambulatory clinic from January 2013-December 2015. Participants were women with hypothyroidism. Chronotype was determined from the Munich ChronoType Questionnaire. The \u03c7<jats:sup>2<\/jats:sup> test was used to compare differences in clinical characteristics and sleep patterns in early and intermediate\/late chronotypes. The <jats:italic>t<\/jats:italic> test was used to compare differences between means.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We evaluated 99 patients (mean [SD], 56 [7] years): calculated chronotype revealed: 56% early, 38% intermediate and 6% late. Analysis with the \u03c7<jats:sup>2<\/jats:sup> test showed significant differences between early and intermediate\/late calculated chronotypes for sleep latency (<jats:italic>P<\/jats:italic>\u2009=\u20090.01), light exposure (<jats:italic>P<\/jats:italic>\u2009=\u20090.009), and no alcohol intake (<jats:italic>P<\/jats:italic>\u2009=\u20090.001). <jats:italic>t<\/jats:italic> test showed the following differences in mean (SD) between chronotypes: sleep duration, 7.30 (1.39) hours (early chronotype) and 7.04 (2.06) hours (intermediate\/late); body mass index (BMI), 29.4 (7.3) (early) and 31.1 (6.8) (intermediate\/late); and TSH level, 2.89 (3.69) mIU\/L (early) and 1.69 (1.41) mIU\/L (intermediate\/late). Early chronotypes were frequent in women with hypothyroidism. Light exposure and BMI may influence chronotypes in patients with hypothyroidism; findings are consistent with healthier behaviors in patients who tend toward morningness.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13104-022-05934-3","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T12:03:03Z","timestamp":1644840183000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Primary hypothyroidism and chronotypes in adult women"],"prefix":"10.1186","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8185-4707","authenticated-orcid":false,"given":"Marilyn A.","family":"Arosemena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto R.","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin N.","family":"Marcus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna A.","family":"Slota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo R.","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,2,14]]},"reference":[{"issue":"1","key":"5934_CR1","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1177\/0748730402239679","volume":"18","author":"T Roenneberg","year":"2003","unstructured":"Roenneberg T, Wirz-Justice A, Merrow M. Life between clocks: daily temporal patterns of human chronotypes. J Biol Rhythms. 2003;18(1):80\u201390.","journal-title":"J Biol Rhythms"},{"issue":"10","key":"5934_CR2","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1016\/j.sleep.2012.07.006","volume":"13","author":"PV Krishnan","year":"2012","unstructured":"Krishnan PV, Vadivu AS, Alappatt A, Kameswaran M. Prevalence of sleep abnormalities and their association among hypothyroid patients in an Indian population. Sleep Med. 2012;13(10):1232\u20137.","journal-title":"Sleep Med"},{"issue":"2","key":"5934_CR3","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1007\/s11325-018-1746-z","volume":"23","author":"M Bruyneel","year":"2019","unstructured":"Bruyneel M, Veltri F, Poppe K. Prevalence of newly established thyroid disorders in patients with moderate-to-severe obstructive sleep apnea syndrome. 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