{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T21:13:21Z","timestamp":1776114801713,"version":"3.50.1"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Thoracoscopy under local anaesthesia is widely performed to diagnose malignancies and infectious diseases. However, few reports have described the use of this procedure for diagnosing and treating intrathoracic infections. This study aimed to evaluate the safety and efficacy of thoracoscopy under local anaesthesia for the management of intrathoracic infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Data from patients who underwent thoracoscopy procedures performed by chest physicians under local anaesthesia at our hospital between January 2018 and December 2023 were retrospectively reviewed. We analysed their demographic factors, reasons for the examinations, diseases targeted, examination lengths, anaesthetic methods used, diagnostic and treatment success rates, as well as any adverse events. Thirty patients were included. Of these, 12 (40%) had thoracoscopies to diagnose infections, and 18 (60%) had them to treat pyothorax. In terms of diagnosing pleurisy, the causative microorganism of origin was identified via thoracoscopy in only three of 12 (25.0%) patients. For diagnosing pyothorax, the causative microorganism was identified in 7 of 18 (38.9%) patients. Methicillin-resistant\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      was the most common causative microorganism identified. The treatment success rates were very high, ranging between 94.4 and 100%, whereas the identification rate of the causative microorganisms behind infections was low, ranging between 25.0 and 38.9%. The most frequent adverse events included perioperative hypoxaemia and pain. There were two (6.7%) serious adverse events of grade\u2009\u2265\u20093, but none resulted in death.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The efficacy of managing intrathoracic infections through thoracoscopy under local anaesthesia is commendable. Nonetheless, the diagnostic accuracy of the procedure, regarding the precise identification of the causative microorganisms responsible for intrathoracic infections, persists at a notably low level, presenting a substantial clinical hurdle.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13104-024-06794-9","type":"journal-article","created":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T23:17:32Z","timestamp":1714951052000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Single-centre observational study of the safety and efficacy of thoracoscopy under local anaesthesia for the management of thoracic infections"],"prefix":"10.1186","volume":"17","author":[{"given":"Kohei","family":"Fujita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zentaro","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanori","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuma","family":"Imakita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issei","family":"Oi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Kanai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Hata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Sawai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiminobu","family":"Tanizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,6]]},"reference":[{"issue":"4","key":"6794_CR1","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/j.ccm.2021.08.010","volume":"42","author":"SK Avasarala","year":"2021","unstructured":"Avasarala SK, Lentz RJ, Maldonado F. Medical thoracoscopy. Clin Chest Med. 2021;42(4):751\u201366.","journal-title":"Clin Chest Med"},{"issue":"10","key":"6794_CR2","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.3390\/healthcare10101978","volume":"10","author":"D Li","year":"2022","unstructured":"Li D, Jackson K, Panchal R, Aujayeb A. Local anaesthetic thoracoscopy for pleural effusion\u2014a narrative review. Healthcare. 2022;10(10):1978.","journal-title":"Healthcare"},{"issue":"1","key":"6794_CR3","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jiac.2020.08.008","volume":"27","author":"S Fujimoto","year":"2021","unstructured":"Fujimoto S, Saito K, Matsubayashi S, Sato A, Yamada M, Yamanaka Y, et al. Clinical utility of thoracoscopy in elderly tuberculous pleurisy patients under local anesthesia. J Infect Chemother. 2021;27(1):40\u20134.","journal-title":"J Infect Chemother"},{"issue":"8","key":"6794_CR4","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1007\/s11748-014-0405-y","volume":"62","author":"M Ohuchi","year":"2014","unstructured":"Ohuchi M, Inoue S, Ozaki Y, Fujita T, Igarashi T, Ueda K, et al. Single-trocar thoracoscopy under local anesthesia for pleural space infection. Gen Thorac Cardiovasc Surg. 2014;62(8):503\u201310.","journal-title":"Gen Thorac Cardiovasc Surg"},{"issue":"3","key":"6794_CR5","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1097\/LBR.0b013e3181e6a2e7","volume":"17","author":"A Mohan","year":"2010","unstructured":"Mohan A, Chandra S, Agarwal D, Naik S, Munavvar M. Utility of semirigid thoracoscopy in the diagnosis of pleural effusions: a systematic review. 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Accessed 10 Feb 2024."},{"issue":"1","key":"6794_CR13","doi-asserted-by":"publisher","first-page":"10","DOI":"10.58585\/respend.2023-0032","volume":"2","author":"K Fujita","year":"2024","unstructured":"Fujita K, Saito Z, Ito T, Yoden M, Imakita T, Oi I, et al. Comparison of the efficacy and safety of thoracoscopy under local anesthesia in patients aged over and under 75 years: a single-center experience. Respir Endosc. 2024;2(1):10\u20137.","journal-title":"Respir Endosc"}],"container-title":["BMC Research Notes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13104-024-06794-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13104-024-06794-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13104-024-06794-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T23:19:07Z","timestamp":1714951147000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcresnotes.biomedcentral.com\/articles\/10.1186\/s13104-024-06794-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,6]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["6794"],"URL":"https:\/\/doi.org\/10.1186\/s13104-024-06794-9","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3975572\/v1","asserted-by":"object"}]},"ISSN":["1756-0500"],"issn-type":[{"value":"1756-0500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,6]]},"assertion":[{"value":"21 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This clinical trial was approved by the National Hospital Organization Kyoto Medical Center institutional review board (approval number: 23\u2013051). The study is registered in the UMIN-Clinical Trials Registry as a retrospective study. The registration number is UMIN000053688. The study is a retrospective nature and no consent forms were obtained from patients. Instead, an opt-out method is used, which guarantees the right of research subjects to refuse to participate in the study. The Ethics Committee of the NHO Kyoto Medical Centre has approved these methods.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Kohei Fujita has received research funds under contracts from MSD, AstraZeneca, and AN2 Therapeutics outside of the submitted work. Osamu Kanai has received research funds under contract from AstraZeneca outside the submitting work. Yuki Yamamoto is a board member and a stockholder of HiLung, Inc. All the other authors have no conflicts of interest to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"127"}}