{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:28:03Z","timestamp":1772166483838,"version":"3.50.1"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"International Liver Foundation","award":["02\/2020"],"award-info":[{"award-number":["02\/2020"]}]},{"name":"International Liver Foundation","award":["02\/2020"],"award-info":[{"award-number":["02\/2020"]}]},{"name":"International Liver Foundation","award":["02\/2020"],"award-info":[{"award-number":["02\/2020"]}]},{"name":"International Liver Foundation","award":["02\/2020"],"award-info":[{"award-number":["02\/2020"]}]},{"name":"International Liver Foundation","award":["02\/2020"],"award-info":[{"award-number":["02\/2020"]}]},{"name":"International Liver Foundation","award":["02\/2020"],"award-info":[{"award-number":["02\/2020"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of the study was to understand the role of self-reported drinking behavior on liver health after achieving sustained viral response (SVR) among HCV patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study was conducted in HCV treatment provider clinics in three cities in Georgia: Tbilisi, Batumi, and Telavi. Face-to-face interviews were conducted using a questionnaire developed specifically for this study. 9.5% considered themselves heavy drinkers, while 94.2% were aware that heavy alcohol consumption can progress liver fibrosis. During treatment, 97.8% abstained from alcohol, while 76.6% reported resuming drinking after achieving SVR. Additionally, 52.1% believed that moderate alcohol intake is normal for individuals with low fibrosis scores. Liver fibrosis improvement was more prevalent among individuals who abstained from alcohol after HCV diagnosis (85.4% vs. 71.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01) and after achieving SVR (87.5% vs. 74.7% of those who resumed drinking after achieving SVR,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.02). In conclusion, the majority of HCV patients abstain from alcohol during treatment but resume drinking after achieving SVR. Those who abstain from alcohol intake after HCV cure have a higher chance of liver fibrosis improvement.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13104-024-06814-8","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T15:01:26Z","timestamp":1718031686000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of alcohol use behavior among patients cured through HCV elimination program in Georgia"],"prefix":"10.1186","volume":"17","author":[{"given":"Maia","family":"Butsashvili","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lasha","family":"Gulbiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgi","family":"Kanchelashvili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Kamkamidze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maia","family":"Kajaia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salome","family":"Gudavadze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Kamkamidze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,10]]},"reference":[{"issue":"8","key":"6814_CR1","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1016\/j.cgh.2023.04.015","volume":"21","author":"ZM Younossi","year":"2023","unstructured":"Younossi ZM, Wong G, Anstee QM. The Global Burden of Liver Disease. Clin Gastroenterol Hepatol. 2023;21(8):1978\u201391.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"6814_CR2","doi-asserted-by":"crossref","unstructured":"Tapper EB, Parikh ND. Mortality due to cirrhosis and liver cancer in the United States, 1999\u20132016: observational study. BMJ. 2018; 362:k2817. https:\/\/www.bmj.com\/content\/362\/bmj.k2817.","DOI":"10.1136\/bmj.k2817"},{"key":"6814_CR3","doi-asserted-by":"crossref","unstructured":"Yakovlev E. Alcoholism and mortality in Eastern Europe. IZA World of Labor. 2015;2. https:\/\/wol.iza.org\/articles\/alcoholism-and-mortality-in-eastern-europe\/long.","DOI":"10.15185\/izawol.168"},{"key":"6814_CR4","doi-asserted-by":"publisher","first-page":"106153","DOI":"10.1016\/j.ypmed.2020.106153","volume":"138","author":"S Shadaker","year":"2020","unstructured":"Shadaker S, Nasrullah M, Gamkrelidze A, Ray J, Gvinjilia L, Kuchuloria T, et al. Screening and linkage to care for hepatitis C among inpatients in Georgia\u2019s national hospital screening program. Prev Med. 2020;138:106153. https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0091743520301778?via%3Dihub. Available from:.","journal-title":"Prev Med"},{"key":"6814_CR5","doi-asserted-by":"crossref","unstructured":"Gamkrelidze A, Shadaker S, Tsereteli M, Alkhazashvili M, Chitadze N, Tskhomelidze I et al. Nationwide hepatitis C serosurvey and progress towards HCV elimination in the country of Georgia, 2021. The Journal of Infectious Diseases. 2023; https:\/\/pubmed.ncbi.nlm.nih.gov\/36932731\/.","DOI":"10.1093\/infdis\/jiad064"},{"key":"6814_CR6","doi-asserted-by":"crossref","unstructured":"Averhoff F, Shadaker S, Amiran Gamkrelidze T, Kuchuloria, Gvinjilia L, Getia V et al. Progress and challenges of a pioneering hepatitis C elimination program in the country of Georgia. JOURNAL OF HEPATOLOGY. 2020; 72(4):680\u20137. https:\/\/www.journal-of-hepatology.eu\/article\/S0168-8278(19)30710-X\/fulltext.","DOI":"10.1016\/j.jhep.2019.11.019"},{"key":"6814_CR7","unstructured":"Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG. The Alcohol Use Disorder Identification Test: Guidelines for Use in Primary Care, Second Edition. World Health Organization, 2001. https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/67205\/WHO_MSD_MSB_01.6a.pdf."},{"issue":"3","key":"6814_CR8","doi-asserted-by":"publisher","first-page":"e13056","DOI":"10.1111\/eci.13056","volume":"49","author":"EG Giannini","year":"2019","unstructured":"Giannini EG, Crespi M, Demarzo M, Bodini G, Furnari M, Marabotto E, Torre F, Zentilin P, Savarino V. Improvement in hepatitis C virus patients with advanced, compensated liver disease after sustained virological response to direct acting antivirals. Eur J Clin Invest. 2019;49(3):e13056. https:\/\/doi.org\/10.1111\/eci.13056.","journal-title":"Eur J Clin Invest"},{"key":"6814_CR9","unstructured":"National Institute on Alcohol Abuse and Alcoholism. Overview of Alcohol Consumption: Moderate & Binge Drinking. https:\/\/www.niaaa.nih.gov\/alcohol-health\/overview-alcohol-consumption\/moderate-binge-drinking."},{"key":"6814_CR10","doi-asserted-by":"crossref","unstructured":"Alavian SM, Haghbin H. Relative Importance of Hepatitis B and C Viruses in Hepatocellular Carcinoma in EMRO Countries and the Middle East: A Systematic Review. Hepatitis Monthly. 2016; 16(3). https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4875504\/.","DOI":"10.5812\/hepatmon.35106"},{"key":"6814_CR11","doi-asserted-by":"crossref","unstructured":"Goldberg D, Ditah IC, Saeian K, Lalehzari M, Aronsohn A, Gorospe EC et al. Changes in the Prevalence of Hepatitis C Virus Infection, Nonalcoholic Steatohepatitis, and Alcoholic Liver Disease Among Patients With Cirrhosis or Liver Failure on the Waitlist for Liver Transplantation. Gastroenterology. 2017;152(5):1090\u20131099.e1. https:\/\/www.gastrojournal.org\/article\/S0016-5085(17)30014-8\/fulltext.","DOI":"10.1053\/j.gastro.2017.01.003"},{"key":"6814_CR12","doi-asserted-by":"crossref","unstructured":"Campbell JA, Hagan H, Latka MH, Garfein RS, Golub ET, Coady MH et al. High prevalence of alcohol use among hepatitis C virus antibody positive injection drug users in three US cities. Drug and Alcohol Dependence. 2006 Feb 28 https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0376871605002243?via%3Dihub.","DOI":"10.1016\/j.drugalcdep.2005.07.005"},{"key":"6814_CR13","unstructured":"Patel Y, Yao J. Scholars@Duke publication: Reduced Alcohol Use Is Sustained in Patients Provided Alcohol-Related Counseling During Direct-Acting Antiviral Therapy for Hepatitis C. scholars.duke.edu. 2021. https:\/\/scholars.duke.edu\/publication\/1460743."}],"container-title":["BMC Research Notes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13104-024-06814-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13104-024-06814-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13104-024-06814-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T15:01:53Z","timestamp":1718031713000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcresnotes.biomedcentral.com\/articles\/10.1186\/s13104-024-06814-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,10]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["6814"],"URL":"https:\/\/doi.org\/10.1186\/s13104-024-06814-8","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3294776\/v1","asserted-by":"object"}]},"ISSN":["1756-0500"],"issn-type":[{"value":"1756-0500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,10]]},"assertion":[{"value":"25 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The full name of the organization to which the ethics committee that approved this study belongs is Health Research Union (IRB00009520; IORG0005619). All participants were enrolled in the survey after signing the informed consent form. We confirm that all the procedures were followed in accordance with the relevant guidelines and regulations such as the Declaration of Helsinki and the Belmont Report.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"We declare that the authors of this paper have no competing interests as defined by BMC, or other interests that might be perceived to influence the results and\/or discussion reported in this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"160"}}