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Low barometric pressure is a factor in headache triggering, but sex-related differences have not been identified. The purpose of this study was to examine sex-related differences in headache triggered by low barometric pressure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Study subjects aged 20\u201349 years were randomly selected from a research company\u2019s (Macromill, Inc.) web panel. Those with chronic migraine or tension-type headache invited to complete a web-based self-administered questionnaire. Logistic regression analysis was performed with the objective variable as the Headache Impact Test-6 (HIT-6) high scores (56 or more) or headache triggered by low barometric pressure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Participants were 332 women and 337 men in the headache population. HIT-6 high scores were associated with age at headache occurrence 20 years or younger (OR: odds ratio 1.85, 95% CI: confidence interval 1.15\u20132.99, <jats:italic>p<\/jats:italic>\u2009=\u20090.012) and headache triggered by low barometric pressure (OR 2.11, 95%CI 1.51\u20132.94, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Headache triggered by low barometric pressure was significantly associated with women (OR 2.92, 95%CI 2.12\u20134.02, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Headache triggered by low barometric pressure were related to sex-related differences. It was suggested that a sex-specific treatment approach for headache triggering is needed.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13104-024-06827-3","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T18:28:52Z","timestamp":1721759332000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Sex-related differences regarding headache triggered by low barometric pressure in Japan"],"prefix":"10.1186","volume":"17","author":[{"given":"Takuma","family":"Fujimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsunori","family":"Yamaura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,23]]},"reference":[{"issue":"3","key":"6827_CR1","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.tips.2009.12.001","volume":"31","author":"TJ Nicolson","year":"2010","unstructured":"Nicolson TJ, Mellor HR, Roberts RRA. 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