{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:52:38Z","timestamp":1775818358966,"version":"3.50.1"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>Studies that have examined the correlation between reproductive history and knee osteoarthritis (KOA) have had heterogeneous findings. We aimed to investigate the reproductive history and its relationship with pain and physical dysfunction in women with KOA. This case-control study, comprising 204 women aged 50 and older with and without KOA recruited through random cluster sampling, was executed from February 2018 to October 2018 in the health centers of Tabriz City. The reproductive history questionnaire was completed for the subjects in two groups. Pain intensity and functional dysfunction caused by KOA were evaluated using the Visual analogue scale and the Western Ontario and McMaster index, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The women\u2019s age of menarche in the case group was significantly lower (<jats:italic>p<\/jats:italic>\u2009=\u20090.031), and the number of pregnancies (<jats:italic>p<\/jats:italic>\u2009=\u20090.017) and the average duration of breastfeeding (<jats:italic>p<\/jats:italic>\u2009=\u20090.039) were substantially higher than those of the control group. Older age at the first menstruation (OR\u2009=\u20090.851) was a protective factor, and higher parity (OR\u2009=\u20098.726) was a risk factor for KOA. In the women with KOA, the younger age of the mother at the birth of the first alive baby and the longer duration of breastfeeding were associated with higher pain intensity and functional disorders.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13104-024-06859-9","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T12:02:06Z","timestamp":1721131326000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Reproductive history is associated with functional disabilities and symptoms in women with knee osteoarthritis: a case-control study"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6313-9275","authenticated-orcid":false,"given":"Fariba","family":"Eslamian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Kazem","family":"Shakouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narges","family":"Mohammadpour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda","family":"Dolatkhah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soheila","family":"Bani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh Nazari","family":"Khanmiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,16]]},"reference":[{"key":"6859_CR1","doi-asserted-by":"crossref","unstructured":"Cui A et al. 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Reproductive history, hormonal factors and the incidence of hip and knee replacement for osteoarthritis in middle-aged women. Ann Rheum Dis. 2009;68(7):1165\u201370.","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"6859_CR5","doi-asserted-by":"publisher","first-page":"1654","DOI":"10.1016\/j.joca.2017.06.010","volume":"25","author":"AI Hellevik","year":"2017","unstructured":"Hellevik AI, et al. Age of menarche is associated with knee joint replacement due to primary osteoarthritis (the HUNT study and the Norwegian Arthroplasty Register). Osteoarthr Cartil. 2017;25(10):1654\u201362.","journal-title":"Osteoarthr Cartil"},{"issue":"11","key":"6859_CR6","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1016\/j.joca.2011.07.020","volume":"19","author":"S Wei","year":"2011","unstructured":"Wei S, et al. The associations between parity, other reproductive factors and cartilage in women aged 50\u201380 years. 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At the beginning of the study, the objectives of the design and method were explained in detail for each individual, and written informed consent was obtained from all participants. The subjects were able to exit the study any time they wanted with no reason. No additional costs, no complications or intervention were imposed on patients, and they were not deprived of their routine therapies. The protocol has been discussed and approved by the Ethics Committee of the Tabriz University of Medical Sciences (IR.TBZMED.REC.1397.805).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"196"}}