{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T14:20:07Z","timestamp":1792851607553,"version":"4.5.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T00:00:00Z","timestamp":1725926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T00:00:00Z","timestamp":1725926400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["MNESYS (PE0000006)"],"award-info":[{"award-number":["MNESYS (PE0000006)"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["MNESYS (PE0000006)"],"award-info":[{"award-number":["MNESYS (PE0000006)"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["Ricerca Corrente"],"award-info":[{"award-number":["Ricerca Corrente"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Alz Res Therapy"],"DOI":"10.1186\/s13195-024-01565-x","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T05:03:36Z","timestamp":1725944616000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical, neuropathological, and molecular characteristics of rapidly progressive dementia with Lewy bodies: a distinct clinicopathological entity?"],"prefix":"10.1186","volume":"16","author":[{"given":"Giuseppe Mario","family":"Bentivenga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Baiardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Mastrangelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Ruggeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Mammana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Ticca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Capellari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piero","family":"Parchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,10]]},"reference":[{"key":"1565_CR1","doi-asserted-by":"crossref","unstructured":"Koga S, Sekiya H. Kondru N, Ross OA, Dickson DW. Neuropathology and molecular diagnosis of synucleinopathies. Mol Neurodegener. 2021;16:83.","DOI":"10.1186\/s13024-021-00501-z"},{"key":"1565_CR2","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1007\/s00702-019-02028-6","volume":"126","author":"KA Jellinger","year":"2019","unstructured":"Jellinger KA. Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update\u2014I. Hypokinetic-rigid movement disorders. J Neural Transm. 2019;126:933\u201395.","journal-title":"J Neural Transm"},{"key":"1565_CR3","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/S1474-4422(23)00405-2","volume":"23","author":"T Simuni","year":"2024","unstructured":"Simuni T, Chahine LM, Poston K, Brumm M, Buracchio T, Campbell M et al. A biological definition of neuronal \u03b1-synuclein disease: towards an integrated staging system for research. Lancet Neurol. 2024;23:178\u201390.","journal-title":"Lancet Neurol"},{"key":"1565_CR4","doi-asserted-by":"publisher","first-page":"1935","DOI":"10.1212\/01.wnl.0000247041.63081.98","volume":"67","author":"MM Williams","year":"2006","unstructured":"Williams MM, Xiong C, Morris JC, Galvin JE. Survival and mortality differences between dementia with Lewy bodies vs Alzheimer disease. Neurology. 2006;67:1935\u201341.","journal-title":"Neurology"},{"key":"1565_CR5","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1001\/jamaneurol.2017.0603","volume":"74","author":"R Savica","year":"2017","unstructured":"Savica R, Grossardt BR, Bower JH, Ahlskog JE, Boeve BF, Graff-Radford J, et al. Survival and causes of death among people with clinically diagnosed synucleinopathies with parkinsonism. JAMA Neurol. 2017;74:839\u201346.","journal-title":"JAMA Neurol"},{"key":"1565_CR6","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1212\/WNL.55.9.1401","volume":"55","author":"S Ha\u00efk","year":"2000","unstructured":"Ha\u00efk S, Brandel JP, Sazdovitch V, Delasnerie-Laupr\u00eatre N, Peoc\u2019h K, Laplanche JL, et al. Dementia with Lewy bodies in a neuropathologic series of suspected Creutzfeldt-Jakob disease. Neurology. 2000;55:1401\u20134.","journal-title":"Neurology"},{"key":"1565_CR7","doi-asserted-by":"crossref","unstructured":"Tschampa HJ, Neumann M, Zerr I, Henkel K, Schr\u00f6ter A, Schulz-Schaeffer WJ, et al. Patients with Alzheimer\u2019s disease and dementia with Lewy bodies mistaken for Creutzfeldt-Jakob disease. J Neurol Neurosurg Psychiatry. 2001;71:33\u20139.","DOI":"10.1136\/jnnp.71.1.33"},{"key":"1565_CR8","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1007\/s00415-004-0311-9","volume":"251","author":"B Van Everbroeck","year":"2004","unstructured":"Van Everbroeck B, Dobbeleir I, De Waele M, De Deyn P, Martin J-J, Cras P. Differential diagnosis of 201 possible creutzfeldt-jakob disease patients. J Neurol. 2004;251:298\u2013304.","journal-title":"J Neurol"},{"key":"1565_CR9","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1002\/gps.1602","volume":"21","author":"AW Lemstra","year":"2006","unstructured":"Lemstra AW, Schoenmaker N, Rozemuller-Kwakkel A J M, Van Gool W et al. The association of neuroleptic sensitivity in Lewy body disease with a false positive clinical diagnosis of Creutzfeldt-Jakob disease. Int J Geriatr Psychiatry. 2006;21:1031\u20135.","journal-title":"Int J Geriatr Psychiatry"},{"key":"1565_CR10","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1001\/archneurol.2008.534","volume":"66","author":"KA Josephs","year":"2009","unstructured":"Josephs KA, Ahlskog JE, Parisi JE, Boeve BF, Crum BA, Giannini C et al. Rapidly progressive neurodegenerative dementias. Arch Neurol. 2009;66:201\u20137.","journal-title":"Arch Neurol"},{"key":"1565_CR11","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.1002\/mds.23506","volume":"26","author":"C Gaig","year":"2011","unstructured":"Gaig C, Valldeoriola F, Gelpi E, Ezquerra M, Llufriu S, Buongiorno M, et al. Rapidly progressive diffuse Lewy body disease. Mov Disord. 2011;26:1316\u201323.","journal-title":"Mov Disord"},{"key":"1565_CR12","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1001\/jamaneurol.2016.4926","volume":"74","author":"J Graff-Radford","year":"2017","unstructured":"Graff-Radford J, Aakre J, Savica R, Boeve B, Kremers WK, Ferman TJ, et al. Duration and pathologic correlates of Lewy body disease. JAMA Neurol. 2017;74:310.","journal-title":"JAMA Neurol"},{"key":"1565_CR13","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.parkreldis.2019.02.011","volume":"63","author":"H Geut","year":"2019","unstructured":"Geut H, Vergouw LJM, Galis Y, Ingrassia A, de Jong FJ, Quadri M, et al. Neuropathological and genetic characteristics of a post-mortem series of cases with dementia with Lewy bodies clinically suspected of Creutzfeldt-Jakob\u2019s disease. Parkinsonism Relat Disord. 2019;63:162\u20138.","journal-title":"Parkinsonism Relat Disord"},{"key":"1565_CR14","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1007\/s00401-009-0523-2","volume":"117","author":"I Alafuzoff","year":"2009","unstructured":"Alafuzoff I, Ince PG, Arzberger T, Al-Sarraj S, Bell J, Bodi I, et al. Staging\/typing of Lewy body related \u03b1-synuclein pathology: a study of the BrainNet Europe Consortium. Acta Neuropathol. 2009;117:635\u201352.","journal-title":"Acta Neuropathol"},{"key":"1565_CR15","doi-asserted-by":"crossref","unstructured":"Parchi P, de Boni L, Saverioni D, Cohen ML, Ferrer I, Gambetti P et al. Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA. Acta Neuropathol. 2012;124:517\u201329.","DOI":"10.1007\/s00401-012-1002-8"},{"key":"1565_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00401-011-0910-3","volume":"123","author":"TJ Montine","year":"2012","unstructured":"Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, et al. National institute on Aging\u2013Alzheimer\u2019s association guidelines for the neuropathologic assessment of Alzheimer\u2019s disease: a practical approach. Acta Neuropathol. 2012;123:1\u201311.","journal-title":"Acta Neuropathol"},{"key":"1565_CR17","doi-asserted-by":"publisher","first-page":"a009258","DOI":"10.1101\/cshperspect.a009258","volume":"2","author":"DW Dickson","year":"2012","unstructured":"Dickson DW. Parkinson\u2019s disease and parkinsonism: Neuropathology. Cold Spring Harb Perspect Med. 2012;2:a009258\u2013009258.","journal-title":"Cold Spring Harb Perspect Med"},{"key":"1565_CR18","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1212\/WNL.0000000000004058","volume":"89","author":"IG McKeith","year":"2017","unstructured":"McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor J-P, Weintraub D, et al. Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the DLB consortium. Neurology. 2017;89:88\u2013100.","journal-title":"Neurology"},{"key":"1565_CR19","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/S1474-4422(20)30477-4","volume":"20","author":"P Hermann","year":"2021","unstructured":"Hermann P, Appleby B, Brandel J-P, Caughey B, Collins S, Geschwind MD, et al. Biomarkers and diagnostic guidelines for sporadic creutzfeldt-jakob disease. Lancet Neurol. 2021;20:235\u201346.","journal-title":"Lancet Neurol"},{"key":"1565_CR20","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1186\/s13195-022-01093-6","volume":"14","author":"S Baiardi","year":"2022","unstructured":"Baiardi S, Quadalti C, Mammana A, Dellavalle S, Zenesini C, Sambati L, et al. Diagnostic value of plasma p-tau181, NfL, and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias. Alzheimers Res Ther. 2022;14:153.","journal-title":"Alzheimers Res Ther"},{"key":"1565_CR21","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s13195-017-0331-1","volume":"10","author":"S Abu-Rumeileh","year":"2018","unstructured":"Abu-Rumeileh S, Capellari S, Stanzani-Maserati M, Polischi B, Martinelli P, Caroppo P, et al. The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias. Alzheimers Res Ther. 2018;10:3.","journal-title":"Alzheimers Res Ther"},{"key":"1565_CR22","doi-asserted-by":"crossref","unstructured":"Franceschini A, Baiardi S, Hughson AG, McKenzie N, Moda F, Rossi F et al. High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions. Sci Rep. 2017;7:10655.","DOI":"10.1038\/s41598-017-10922-w"},{"key":"1565_CR23","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s00401-023-02663-0","volume":"147","author":"GM Bentivenga","year":"2024","unstructured":"Bentivenga GM, Mammana A, Baiardi S, Rossi M, Ticca A, Magliocchetti F, et al. Performance of a seed amplification assay for misfolded alpha-synuclein in cerebrospinal fluid and brain tissue in relation to Lewy body disease stage and pathology burden. Acta Neuropathol. 2024;147:18.","journal-title":"Acta Neuropathol"},{"key":"1565_CR24","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1093\/brain\/awz099","volume":"142","author":"PT Nelson","year":"2019","unstructured":"Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, et al. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain. 2019;142:1503\u201327.","journal-title":"Brain"},{"key":"1565_CR25","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s00401-020-02255-2","volume":"141","author":"J Attems","year":"2021","unstructured":"Attems J, Toledo JB, Walker L, Gelpi E, Gentleman S, Halliday G, et al. Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study. Acta Neuropathol. 2021;141:159\u201372.","journal-title":"Acta Neuropathol"},{"key":"1565_CR26","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s00401-008-0366-2","volume":"115","author":"DR Thal","year":"2008","unstructured":"Thal DR, Griffin WST, De Vos RAI, Ghebremedhin E. Cerebral amyloid angiopathy and its relationship to Alzheimer\u2019s disease. Acta Neuropathol. 2008;115:599\u2013609.","journal-title":"Acta Neuropathol"},{"key":"1565_CR27","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1007\/s00401-014-1349-0","volume":"128","author":"JF Crary","year":"2014","unstructured":"Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 2014;128:755\u201366.","journal-title":"Acta Neuropathol"},{"key":"1565_CR28","volume-title":"Techniques in experimental Virology","author":"T Dougherty","year":"1964","unstructured":"Dougherty T. Animal virus titration techniques. In: Harris RJC, editor. Techniques in experimental virology. New York Academic; 1964."},{"key":"1565_CR29","doi-asserted-by":"crossref","unstructured":"Wilham JM, Orr\u00fa CD, Bessen RA, Atarashi R, Sano R, Race K, et al. Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays. PLoS Pathog. 2010;6:e1001217.","DOI":"10.1371\/journal.ppat.1001217"},{"key":"1565_CR30","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1099\/vir.0.069906-0","volume":"96","author":"DM Henderson","year":"2015","unstructured":"Henderson DM, Davenport KA, Haley NJ, Denkers ND, Mathiason CK, Hoover EA. Quantitative assessment of prion infectivity in tissues and body fluids by real-time quaking-induced conversion. J Gen Virol. 2015;96:210\u20139.","journal-title":"J Gen Virol"},{"key":"1565_CR31","doi-asserted-by":"publisher","first-page":"D1062","DOI":"10.1093\/nar\/gkx1153","volume":"46","author":"MJ Landrum","year":"2018","unstructured":"Landrum MJ, Lee JM, Benson M, Brown GR, Chao C, Chitipiralla S, et al. ClinVar: improving access to variant interpretations and supporting evidence. Nucleic Acids Res. 2018;46:D1062\u20137.","journal-title":"Nucleic Acids Res"},{"key":"1565_CR32","unstructured":"Genoox. Franklin by Genoox. Available online: https:\/\/franklin.genoox.com. Accessed on 20 April 2024."},{"key":"1565_CR33","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1016\/0140-6736(91)92823-K","volume":"337","author":"PR Wenham","year":"1991","unstructured":"Wenham PR, Price WH, Blandell G. Apolipoprotein E genotyping by one-stage PCR. Lancet. 1991;337:1158\u20139.","journal-title":"Lancet"},{"key":"1565_CR34","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1007\/BF00200914","volume":"87","author":"N Eyal","year":"1991","unstructured":"Eyal N, Firon N, Wilder S, Kolodny EH, Horowitz M. Three unique base pair changes in a family with Gaucher disease. Hum Genet. 1991;87:328\u201332.","journal-title":"Hum Genet"},{"key":"1565_CR35","doi-asserted-by":"publisher","first-page":"148","DOI":"10.3389\/fgene.2014.00148","volume":"5","author":"M Manickam","year":"2014","unstructured":"Manickam M, Ravanan P, Singh P, Talwar P. In silico identification of genetic variants in glucocerebrosidase (GBA) gene involved in Gaucher\u2019s disease using multiple software tools. Front Genet. 2014;5:148.","journal-title":"Front Genet"},{"key":"1565_CR36","doi-asserted-by":"crossref","unstructured":"Grau-Rivera O, Gelpi E, Nos C, Gaig C, Ferrer I, Saiz A, et al. Clinicopathological correlations and concomitant pathologies in rapidly progressive dementia: a brain bank series. Neurodegener Dis. 2015;15:350\u201360.","DOI":"10.1159\/000439251"},{"key":"1565_CR37","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1002\/ana.22454","volume":"70","author":"N Chitravas","year":"2011","unstructured":"Chitravas N, Jung RS, Kofskey DM, Blevins JE, Gambetti P, Leigh RJ, et al. Treatable neurological disorders misdiagnosed as Creutzfeldt-Jakob disease. Ann Neurol. 2011;70:437\u201344.","journal-title":"Ann Neurol"},{"key":"1565_CR38","doi-asserted-by":"crossref","unstructured":"Peckeu L, Delasnerie-Laupr\u00e8tre N, Brandel J-P, Salomon D, Sazdovitch V, Laplanche J-L, et al. Accuracy of diagnosis criteria in patients with suspected diagnosis of sporadic Creutzfeldt-Jakob disease and detection of 14-3-3 protein. Euro Surveill. 2017;22:16\u201300715.","DOI":"10.2807\/1560-7917.ES.2017.22.41.16-00715"},{"key":"1565_CR39","doi-asserted-by":"publisher","first-page":"109640","DOI":"10.1016\/j.yebeh.2024.109640","volume":"152","author":"L Chen","year":"2024","unstructured":"Chen L, Yang W, Yang F, Yu Y, Xu T, Wang D, et al. The crosstalk between epilepsy and dementia: a systematic review and meta-analysis. Epilepsy Behav. 2024;152:109640.","journal-title":"Epilepsy Behav"},{"key":"1565_CR40","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1212\/WNL.0000000000009323","volume":"94","author":"IG McKeith","year":"2020","unstructured":"McKeith IG, Ferman TJ, Thomas AJ, Blanc F, Boeve BF, Fujishiro H, et al. Research criteria for the diagnosis of prodromal dementia with Lewy bodies. Neurology. 2020;94:743\u201355.","journal-title":"Neurology"},{"key":"1565_CR41","doi-asserted-by":"publisher","first-page":"418","DOI":"10.3174\/ajnr.A3454","volume":"35","author":"AJ Degnan","year":"2014","unstructured":"Degnan AJ, Levy LM. Neuroimaging of rapidly progressive dementias: part 1: neurodegenerative etiologies. AJNR Am J Neuroradiol. 2014;35:418\u201323.","journal-title":"AJNR Am J Neuroradiol"},{"key":"1565_CR42","doi-asserted-by":"publisher","first-page":"3051","DOI":"10.1093\/brain\/aws238","volume":"135","author":"K Stoeck","year":"2012","unstructured":"Stoeck K, Sanchez-Juan P, Gawinecka J, Green A, Ladogana A, Pocchiari M, et al. Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt\u2013Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years. Brain. 2012;135:3051\u201361.","journal-title":"Brain"},{"key":"1565_CR43","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/s00401-017-1683-0","volume":"133","author":"F Lattanzio","year":"2017","unstructured":"Lattanzio F, Abu-Rumeileh S, Franceschini A, Kai H, Amore G, Poggiolini I, et al. Prion-specific and surrogate CSF biomarkers in Creutzfeldt-Jakob disease: diagnostic accuracy in relation to molecular subtypes and analysis of neuropathological correlates of p-tau and A\u03b242 levels. Acta Neuropathol. 2017;133:559\u201378.","journal-title":"Acta Neuropathol"},{"key":"1565_CR44","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1186\/s13195-023-01300-y","volume":"15","author":"GM Bentivenga","year":"2023","unstructured":"Bentivenga GM, Baiardi S, Mastrangelo A, Zenesini C, Mammana A, Polischi B, et al. Diagnostic and prognostic value of cerebrospinal fluid SNAP-25 and neurogranin in Creutzfeldt-Jakob disease in a clinical setting cohort of rapidly progressive dementias. Alzheimers Res Ther. 2023;15:150.","journal-title":"Alzheimers Res Ther"},{"key":"1565_CR45","doi-asserted-by":"publisher","first-page":"1904","DOI":"10.1002\/acn3.51873","volume":"10","author":"S Abu-Rumeileh","year":"2023","unstructured":"Abu-Rumeileh S, Halbgebauer S, Bentivenga GM, Barba L, Baiardi S, Mastrangelo A, et al. High diagnostic performance of plasma and cerebrospinal fluid beta-synuclein for sporadic Creutzfeldt\u2013Jakob disease. Ann Clin Transl Neurol. 2023;10:1904\u20139.","journal-title":"Ann Clin Transl Neurol"},{"key":"1565_CR46","doi-asserted-by":"publisher","first-page":"e50","DOI":"10.1212\/WNL.0000000000207371","volume":"101","author":"L Barba","year":"2023","unstructured":"Barba L, Abu-Rumeileh S, Halbgebauer S, Bellomo G, Paolini Paoletti F, Gaetani L, et al. CSF synaptic biomarkers in AT(N)-Based subgroups of Lewy body disease. Neurology. 2023;101:e50\u201362.","journal-title":"Neurology"},{"key":"1565_CR47","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/s40478-020-00990-x","volume":"8","author":"N Candelise","year":"2020","unstructured":"Candelise N, Baiardi S, Franceschini A, Rossi M, Parchi P. Towards an improved early diagnosis of neurodegenerative diseases: the emerging role of in vitro conversion assays for protein amyloids. Acta Neuropathol Commun. 2020;8:117.","journal-title":"Acta Neuropathol Commun"},{"key":"1565_CR48","doi-asserted-by":"crossref","unstructured":"Saint-Aubert L, Pariente J, Dumas H, Payoux P, Brandel J-P, Puel M, et al. Case report of Lewy body disease mimicking Creutzfeldt-Jakob disease in a 44-year-old man. BMC Neurol. 2016;16:122.","DOI":"10.1186\/s12883-016-0643-y"},{"key":"1565_CR49","doi-asserted-by":"crossref","unstructured":"Ferman TJ, Aoki N, Crook JE, Murray ME, Graff-Radford NR, van Gerpen JA, et al. The limbic and neocortical contribution of \u03b1-synuclein, tau, and amyloid \u03b2 to disease duration in dementia with Lewy bodies. Alzheimers Dement. 2018;14:330\u20139.","DOI":"10.1016\/j.jalz.2017.09.014"},{"key":"1565_CR50","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S1474-4422(16)30291-5","volume":"16","author":"DJ Irwin","year":"2017","unstructured":"Irwin DJ, Grossman M, Weintraub D, Hurtig HI, Duda JE, Xie SX, et al. Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis. Lancet Neurol. 2017;16:55\u201365.","journal-title":"Lancet Neurol"},{"key":"1565_CR51","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1007\/s00702-021-02345-9","volume":"128","author":"KA Jellinger","year":"2021","unstructured":"Jellinger KA. Significance of cerebral amyloid angiopathy and other co-morbidities in Lewy body diseases. J Neural Transm. 2021;128:687\u201399.","journal-title":"J Neural Transm"},{"key":"1565_CR52","first-page":"804","volume":"140","author":"PA Boyle","year":"2017","unstructured":"Boyle PA, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, et al. Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline. Brain. 2017;140:804\u201312.","journal-title":"Brain"},{"key":"1565_CR53","doi-asserted-by":"publisher","first-page":"3541","DOI":"10.1007\/s10072-022-06031-w","volume":"43","author":"L Liu","year":"2022","unstructured":"Liu L, Li J, Quan W, Qin Y, Zhang Q, Pei X, et al. Effect of GBA gene variants on clinical characteristics of dementia with Lewy bodies: a review and meta-analyses. Neurol Sci. 2022;43:3541\u201350.","journal-title":"Neurol Sci"},{"key":"1565_CR54","doi-asserted-by":"publisher","first-page":"89","DOI":"10.3389\/fneur.2017.00089","volume":"8","author":"P Garcia-Esparcia","year":"2017","unstructured":"Garcia-Esparcia P, L\u00f3pez-Gonz\u00e1lez I, Grau-Rivera O, Garc\u00eda-Garrido MF, Konetti A, Llorens F, et al. Dementia with Lewy bodies: molecular pathology in the frontal cortex in typical and rapidly progressive forms. Front Neurol. 2017;8:89.","journal-title":"Front Neurol"}],"container-title":["Alzheimer's Research &amp; Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13195-024-01565-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13195-024-01565-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13195-024-01565-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T06:10:26Z","timestamp":1725948626000},"score":1,"resource":{"primary":{"URL":"https:\/\/alzres.biomedcentral.com\/articles\/10.1186\/s13195-024-01565-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,10]]},"references-count":54,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["1565"],"URL":"https:\/\/doi.org\/10.1186\/s13195-024-01565-x","relation":{},"ISSN":["1758-9193"],"issn-type":[{"value":"1758-9193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,10]]},"assertion":[{"value":"10 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted according to the revised Declaration of Helsinki and Good Clinical Practice guidelines and approved by the local ethics committee Area Vasta Emilia Centro (CE-AVEC) (approval number: 18025: 113\/2018\/OSS\/AUSLBO). Written informed consent was given by study participants or the next of kin.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"201"}}