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The incidence of allergic rhinitis in grassland areas was significantly higher than that in non-grassland areas. We aimed to compare the profiles of chronic rhinitis patients obtained during the autumn pollen season in Baotou (grassland city) and Beijing (non-grassland city), China.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Questionnaire surveys and allergen testing were conducted on 1170 and 1232 patients with chronic rhinitis visiting the Second Affiliated Hospital of Baotou Medical College and Beijing Tongren Hospital, respectively, during the autumn pollen period. Information regarding medical history, severity of symptoms, and diagnosis and treatment was collected.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>More patients with moderate to severe chronic rhinitis and asthma (both, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) were present in Baotou than in Beijing. Mugwort was the most abundant allergen in both regions, but the number of patients sensitized to outdoor allergens in Baotou was higher than that in Beijing (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Indoor allergens in Beijing represented a considerable proportion of allergens, especially dust mites (33.4%). For patients with allergic rhinitis, nasal congestion, nasal itching, and runny nose were more severe in Baotou than in Beijing (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). In both Baotou and Beijing, allergy (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001 vs. <jats:italic>P<\/jats:italic>\u2009=\u20090.004) and combined asthma (<jats:italic>P<\/jats:italic>\u2009=\u20090.049 vs. <jats:italic>P<\/jats:italic>\u2009=\u20090.005) were common factors affecting the severity of the clinical symptoms chronic rhinitis. In Baotou, age (<jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub>\u2009=\u20090.195, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and family allergy history (<jats:italic>P<\/jats:italic>\u2009=\u20090.010) were also associated with symptom severity. Although significantly more patients in Baotou received oral antihistamines, nasal corticosteroids, and surgical treatment than in Beijing (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), the number of people receiving allergy immunotherapy in Baotou was lower (<jats:italic>P<\/jats:italic>\u2009=\u20090.004) and post-treatment symptom control was worse (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) that that in Beijing.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>During the pollen period, there were significant differences in the allergen spectrum between Baotou and Beijing. Allergy and combined asthma were common factors affecting the severity of clinical symptoms. Patients in Baotou presented with more severe clinical symptoms that were not satisfactorily managed due to the impact of pollen exposure, inconsistent access to care, and differing treatment modalities.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13223-021-00591-w","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T10:09:07Z","timestamp":1633946947000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparative analysis of chronic rhinitis patient profiles during autumn pollen season between grassland and non-grassland cities in North China"],"prefix":"10.1186","volume":"17","author":[{"given":"Xu","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengshuo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0910-9884","authenticated-orcid":false,"given":"Luo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,11]]},"reference":[{"key":"591_CR1","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1111\/all.13640","volume":"74","author":"Y Meng","year":"2019","unstructured":"Meng Y, Lou H, Wang Y, Wang X, Cao F, Wang K, et al. 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