{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T08:03:00Z","timestamp":1793520180186,"version":"4.5.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"GSK","award":["Study Numbers: 208086 and 213369"],"award-info":[{"award-number":["Study Numbers: 208086 and 213369"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Allergy Asthma Clin Immunol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this letter to the editor, we present questionnaire-based data assessing the patient journey of adults with moderate\u2013severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in the USA and five European countries. These data highlight how long and difficult the patient journey with CRSwNP can be and how improved disease awareness among physicians could lead to more timely diagnosis and treatment, and hence improved management of patients.<\/jats:p>","DOI":"10.1186\/s13223-024-00879-7","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T13:02:22Z","timestamp":1708952542000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The chronic rhinosinusitis with nasal polyp patient journey in the United States and Europe"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2623-7706","authenticated-orcid":false,"given":"Jeremiah","family":"Hwee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Small","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven G.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria S.","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"issue":"1","key":"879_CR1","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1038\/s41572-020-00218-1","volume":"6","author":"C Bachert","year":"2020","unstructured":"Bachert C, Marple B, Schlosser RJ, Hopkins C, Schleimer RP, Lambrecht BN, et al. Adult chronic rhinosinusitis. Nat Rev Dis Primers. 2020;6(1):86.","journal-title":"Nat Rev Dis Primers"},{"issue":"678","key":"879_CR2","doi-asserted-by":"publisher","first-page":"44","DOI":"10.3399\/bjgp19X700637","volume":"69","author":"PG Deutsch","year":"2019","unstructured":"Deutsch PG, Lord S, Salamat S, Jolly K. The management of chronic rhinosinusitis in primary care: an evidence-based guide. Br J Gen Pract. 2019;69(678):44\u20135.","journal-title":"Br J Gen Pract"},{"key":"879_CR3","doi-asserted-by":"crossref","unstructured":"Bachert C, Bhattacharyya N, Desrosiers M, Khan AH. Burden of disease in chronic rhinosinusitis with nasal polyps. J Asthma Allergy. 2021;14:127\u201334.","DOI":"10.2147\/JAA.S290424"},{"key":"879_CR4","doi-asserted-by":"crossref","unstructured":"Claeys N, Teeling MT, Legrand P, Poppe M, Verschueren P, De Prins L, et al. Patients unmet needs in chronic rhinosinusitis with nasal polyps care: a Patient Advisory Board Statement of EUFOREA. Front Allergy. 2021;2:761388.","DOI":"10.3389\/falgy.2021.789425"},{"key":"879_CR5","doi-asserted-by":"crossref","unstructured":"Anderson P, Benford M, Harris N, Karavali M, Piercy J. Real-world physician and patient behaviour across countries: disease-specific programmes - a means to understand. Curr Med Res Opin. 2008;24(11):3063\u201372.","DOI":"10.1185\/03007990802457040"},{"key":"879_CR6","doi-asserted-by":"crossref","unstructured":"Benson V, Chan R, Sousa A, Small M, Scott M, Milligan G, et al. Nasal polyp symptoms: how well do physicians know their patients? J Allergy Clin Immunol. 2020;145(2):AB148.","DOI":"10.1016\/j.jaci.2019.12.479"},{"key":"879_CR7","doi-asserted-by":"crossref","unstructured":"Hwee J, Smith S, Small M, Lee L, Yang S. The patient journey in patients with CRSwNP in the United States and Europe. American Thoracic Society; May 17, 2022; San Francisco, CA. Am J Respir Crit Care Med 2022. p. A3992\u2013A.","DOI":"10.1164\/ajrccm-conference.2022.205.1_MeetingAbstracts.A3992"},{"issue":"4","key":"879_CR8","doi-asserted-by":"publisher","first-page":"e022644","DOI":"10.1136\/bmjopen-2018-022644","volume":"9","author":"J Vennik","year":"2019","unstructured":"Vennik J, Eyles C, Thomas M, Hopkins C, Little P, Blackshaw H, et al. Chronic rhinosinusitis: a qualitative study of patient views and experiences of current management in primary and secondary care. BMJ Open. 2019;9(4):e022644.","journal-title":"BMJ Open"},{"issue":"3","key":"879_CR9","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1002\/lary.26391","volume":"127","author":"AS DeConde","year":"2017","unstructured":"DeConde AS, Mace JC, Levy JM, Rudmik L, Alt JA, Smith TL. Prevalence of polyp recurrence after endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis. Laryngoscope. 2017;127(3):550\u20135.","journal-title":"Laryngoscope"}],"container-title":["Allergy, Asthma &amp; Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13223-024-00879-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13223-024-00879-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13223-024-00879-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T13:09:15Z","timestamp":1708952955000},"score":1,"resource":{"primary":{"URL":"https:\/\/aacijournal.biomedcentral.com\/articles\/10.1186\/s13223-024-00879-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,26]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["879"],"URL":"https:\/\/doi.org\/10.1186\/s13223-024-00879-7","relation":{},"ISSN":["1710-1492"],"issn-type":[{"value":"1710-1492","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,26]]},"assertion":[{"value":"13 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This survey was granted ethical exemption by the Western Institutional Review Board (WIRB; now WIRB-Copernicus Group IRB), Washington, USA (Study numbers: 1187074 [USA]; #1-1162676-1 [EUR5]).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"N\/A.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"JH, SS, VSB, and SZ are employees of GSK and own stocks\/shares. LL and MS are employees of Adelphi Real World, which received GSK funding for this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"17"}}