{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T02:15:15Z","timestamp":1782526515784,"version":"3.54.5"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s13256-017-1264-9","type":"journal-article","created":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T10:53:58Z","timestamp":1491994438000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Acute hepatitis B virus infection with delayed appearance of hepatitis B core antibody in an immunocompromised patient: a case report"],"prefix":"10.1186","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6042-3177","authenticated-orcid":false,"given":"Nicholas","family":"Brousseau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald G.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Gilca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacynthe","family":"Larouche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sema","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Tedder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,4,17]]},"reference":[{"key":"1264_CR1","first-page":"1","volume":"55","author":"Centers for Disease Control and Prevention","year":"2006","unstructured":"Centers for Disease Control and Prevention. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States. Recommendations of the Advisory Committee on Immunization Practices (ACIP). Part II\u202f: Immunization of adults. MMWR. 2006;55:1\u201333.","journal-title":"MMWR"},{"key":"1264_CR2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1186\/s12879-015-0979-8","volume":"15","author":"TV Porgo","year":"2015","unstructured":"Porgo TV, Gilca V, De Serres G, Tremblay M, Skowronski D. Dramatic reduction in hepatitis B through school-based immunization without a routine infant program in a low endemicity region. BMC Infect Dis. 2015;15:227.","journal-title":"BMC Infect Dis"},{"key":"1264_CR3","volume-title":"Viral Hepatitis Surveillance. United States, 2013","author":"Centers for Disease Control and Prevention","year":"2015","unstructured":"Centers for Disease Control and Prevention. Viral Hepatitis Surveillance. United States, 2013. Atlanta: Centers for Disease Control and Prevention; 2015."},{"key":"1264_CR4","volume-title":"Portrait des infections transmissibles sexuellement et par le sang (ITSS) au Qu\u00e9bec","author":"S Venne","year":"2013","unstructured":"Venne S, Lambert G, Blouin K. Portrait des infections transmissibles sexuellement et par le sang (ITSS) au Qu\u00e9bec. Qu\u00e9bec: INSPQ; 2013."},{"key":"1264_CR5","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/hep.1840100210","volume":"10","author":"B M\u00f6ller","year":"1989","unstructured":"M\u00f6ller B, Hopf U, Stemerowicz R, Henze G, Gelderblom H. HBcAg expressed on the surface of circulating Dane particles in patients with hepatitis B virus infection without evidence of anti-HBc formation. Hepatology. 1989;10:179\u201385.","journal-title":"Hepatology"},{"key":"1264_CR6","volume-title":"Protocole d\u2019immunisation du Qu\u00e9bec","author":"Minist\u00e8re de la Sant\u00e9 et des Services sociaux du Qu\u00e9bec","year":"2015","unstructured":"Minist\u00e8re de la Sant\u00e9 et des Services sociaux du Qu\u00e9bec. Protocole d\u2019immunisation du Qu\u00e9bec. 6th ed. Qu\u00e9bec: Minist\u00e8re de la sant\u00e9 et des services sociaux du Qu\u00e9bec; 2015.","edition":"6"},{"key":"1264_CR7","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00430-010-0160-3","volume":"200","author":"RA Pond\u00e9","year":"2011","unstructured":"Pond\u00e9 RA. The underlying mechanisms for the \u201cisolated positivity for the hepatitis B surface antigen (HBsAg)\u201d serological profile. Med Microbiol Immunol. 2011;200:13\u201322.","journal-title":"Med Microbiol Immunol"},{"key":"1264_CR8","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1128\/JCM.00234-06","volume":"44","author":"V Avettand-Fenoel","year":"2006","unstructured":"Avettand-Fenoel V, Thabut D, Katlama C, Poynard T, Thibault V. Immune suppression as the etiology of failure to detect anti-HBc antibodies in patients with chronic hepatitis B virus infection. J Clin Microbiol. 2006;44:2250\u20133.","journal-title":"J Clin Microbiol"},{"key":"1264_CR9","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1002\/hep.1840110218","volume":"11","author":"RA Bhat","year":"1990","unstructured":"Bhat RA, Ulrich PP, Vyas GN. Molecular characterization of a new variant of hepatitis B virus in a persistently infected homosexual man. Hepatology. 1990;11:271\u20136.","journal-title":"Hepatology"},{"key":"1264_CR10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0168-8278(91)90813-Q","volume":"13","author":"M Melegari","year":"1991","unstructured":"Melegari M, Jung MC, Schneider R, Santantonio T, Bagnulo S, Luchena N, et al. Conserved core protein sequences in hepatitis B virus infected patients without anti-HBc. J Hepatol. 1991;13:187\u201391.","journal-title":"J Hepatol"},{"key":"1264_CR11","first-page":"361","volume":"1","author":"GM Vergani","year":"1981","unstructured":"Vergani GM, Locasciulli A, Masera G, Alberti A, Moroni G, Tee DE, et al. Histological evidence of hepatits-B-virus infection with negative serology in children with acute leukemia who develop chronic liver disease. Lancet. 1981;1:361\u20134.","journal-title":"Lancet"},{"key":"1264_CR12","first-page":"7","volume":"23","author":"LF Ellison","year":"2012","unstructured":"Ellison LF, Wilkins K. Canadian trends in cancer prevalence. Health Rep. 2012;23:7\u201316.","journal-title":"Health Rep"},{"key":"1264_CR13","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1542\/peds.105.6.e81","volume":"105","author":"ER Lunn","year":"2000","unstructured":"Lunn ER, Hoggarth BJ, Cook WJ. Prolonged hepatitis B surface antigenemia after vaccination. Pediatrics. 2000;105:e81.","journal-title":"Pediatrics"},{"key":"1264_CR14","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1016\/0264-410X(90)90208-4","volume":"8","author":"P Coursaget","year":"1990","unstructured":"Coursaget P, Yvonnet B, Bourdil C, Busson Y, Chotard J, N\u2019Doye R, et al. Hepatitis B surface antigen reactivity in man due to a new variant of hepatitis B virus. Vaccine. 1990;8:S15\u20137.","journal-title":"Vaccine"},{"key":"1264_CR15","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/jmv.1890420202","volume":"42","author":"G Fiordalisi","year":"1994","unstructured":"Fiordalisi G, Primi D, Tanzi E, Magni E, Incarbone C, Zanetti AR, et al. Hepatitis B virus C gene heterogeneity in a familial cluster of anti-HBc negative chronic carriers. J Med Virol. 1994;42:109\u201314.","journal-title":"J Med Virol"},{"key":"1264_CR16","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0168-8278(96)80024-9","volume":"24","author":"F Zoulim","year":"1996","unstructured":"Zoulim F, Zhang X, Pichoud C, Trepo C. Heterogeneity of hepatitis B virus (HBV) core gene in a patient with HBV-associated cirrhosis and serum negativity for anti-HBc. J Hepatol. 1996;24:155\u201360.","journal-title":"J Hepatol"},{"key":"1264_CR17","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.jaci.2011.08.008","volume":"128","author":"MD Pescovitz","year":"2011","unstructured":"Pescovitz MD, Torgerson TR, Ocheltree E, McGee P, Krause-Steinrauf H, Lachin JM, et al. Effect of rituximab on human in vivo immune responses. J Allergy Clin Immunol. 2011;128:1295\u2013302.","journal-title":"J Allergy Clin Immunol"},{"key":"1264_CR18","first-page":"1","volume":"62","author":"Centers for Disease Control and Prevention","year":"2013","unstructured":"Centers for Disease Control and Prevention. CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management. MMWR. 2013;62:1\u201319.","journal-title":"MMWR"},{"key":"1264_CR19","doi-asserted-by":"crossref","first-page":"17360","DOI":"10.3748\/wjg.v20.i46.17360","volume":"20","author":"BC Phung","year":"2014","unstructured":"Phung BC, Sogni P, Launay O. Hepatitis B and human immunodeficiency virus co-infection. World J Gastroenterol. 2014;20:17360\u20137.","journal-title":"World J Gastroenterol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-017-1264-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T10:44:41Z","timestamp":1498387481000},"score":1,"resource":{"primary":{"URL":"http:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-017-1264-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,17]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1264"],"URL":"https:\/\/doi.org\/10.1186\/s13256-017-1264-9","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,17]]},"article-number":"111"}}