{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:23:27Z","timestamp":1759335807489,"version":"3.37.3"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81370468 and 81671386"],"award-info":[{"award-number":["81370468 and 81671386"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s13256-017-1405-1","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T04:40:04Z","timestamp":1502426404000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Coexistence of congenital left ventricular aneurysm and prominent left ventricular trabeculation in a patient with LDB3 mutation: a case report"],"prefix":"10.1186","volume":"11","author":[{"given":"Shengshuai","family":"Shan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxiao","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengyun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,8,19]]},"reference":[{"key":"1405_CR1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1159\/000092634","volume":"106","author":"MA Ohlow","year":"2006","unstructured":"Ohlow MA. Congenital left ventricular aneurysms and diverticula: definition, pathophysiology, clinical relevance and treatment. Cardiology. 2006;106:63\u201372.","journal-title":"Cardiology"},{"key":"1405_CR2","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1159\/000159122","volume":"112","author":"MA Ohlow","year":"2009","unstructured":"Ohlow MA, Secknus MA, Geller JC, von Korn H, Lauer B. Prevalence and outcome of congenital left ventricular aneurysms and diverticula in an adult population. Cardiology. 2009;112:287\u201393.","journal-title":"Cardiology"},{"key":"1405_CR3","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ijcard.2015.03.050","volume":"185","author":"MA Ohlow","year":"2015","unstructured":"Ohlow MA, von Korn H, Lauer B. Characteristics and outcome of congenital left ventricular aneurysm and diverticulum: Analysis of 809 cases published since 1816. Int J Cardiol. 2015;185:34\u201345.","journal-title":"Int J Cardiol"},{"key":"1405_CR4","unstructured":"Warembourg H, Pauchant M, Ducloux G, Delbecque H, Ketelers JY. [Congenital aneurysm of the left ventricle associated with ventricular septal defect]. Lille M\u00e9dical Journal De La Facult\u00e9 De M\u00e9decine Et De Pharmacie De Luniversit\u00e9 De Lille. 1974;19:12\u20137."},{"key":"1405_CR5","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/clc.20875","volume":"34","author":"MA Ohlow","year":"2011","unstructured":"Ohlow MA, Fuhrmann JT, Lauer B. Prevalence and spectrum of coronary artery anomalies in patients with an isolated congenital left ventricular aneurysm or diverticulum. Clin Cardiol. 2011;34:226\u201332.","journal-title":"Clin Cardiol"},{"key":"1405_CR6","first-page":"105","volume":"1","author":"CH Chang","year":"1974","unstructured":"Chang CH. Total correction of a syndrome consisting of left ventricular diverticulum, atrial septal defect, Tetralogy of Fallot and midline thoracoabdominal defect. Cardiovasc Dis. 1974;1:105\u20138.","journal-title":"Cardiovasc Dis"},{"key":"1405_CR7","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/j.ijcard.2012.05.095","volume":"167","author":"BE Stahli","year":"2013","unstructured":"Stahli BE, Gebhard C, Biaggi P, Klaassen S, Valsangiacomo Buechel E, Attenhofer Jost CH, Jenni R, Tanner FC, Greutmann M. Left ventricular non-compaction: prevalence in congenital heart disease. Int J Cardiol. 2013;167:2477\u201381.","journal-title":"Int J Cardiol"},{"key":"1405_CR8","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1161\/CIRCGENETICS.113.000362","volume":"7","author":"G Captur","year":"2014","unstructured":"Captur G, Lopes LR, Patel V, Li C, Bassett P, Syrris P, Sado DM, Maestrini V, Mohun TJ, McKenna WJ, et al. Abnormal cardiac formation in hypertrophic cardiomyopathy: fractal analysis of trabeculae and preclinical gene expression. Circ Cardiovasc Genet. 2014;7:241\u20138.","journal-title":"Circ Cardiovasc Genet"},{"key":"1405_CR9","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1093\/ehjci\/jet064","volume":"14","author":"P Marchal","year":"2013","unstructured":"Marchal P, Lairez O, Cognet T, Chabbert V, Barrier P, Berry M, Mejean S, Roncalli J, Rousseau H, Carrie D, Galinier M. Relationship between left ventricular sphericity and trabeculation indexes in patients with dilated cardiomyopathy: a cardiac magnetic resonance study. Eur Heart J Cardiovasc Imaging. 2013;14:914\u201320.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"1405_CR10","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.cjca.2015.07.003","volume":"31","author":"G Captur","year":"2015","unstructured":"Captur G, Syrris P, Obianyo C, Limongelli G, Moon JC. Formation and Malformation of Cardiac Trabeculae: Biological Basis, Clinical Significance, and Special Yield of Magnetic Resonance Imaging in Assessment. Can J Cardiol. 2015;31:1325\u201337.","journal-title":"Can J Cardiol"},{"key":"1405_CR11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.cardfail.2009.01.006","volume":"15","author":"RE Hershberger","year":"2009","unstructured":"Hershberger RE, Lindenfeld J, Mestroni L, Seidman CE, Taylor MR, Towbin JA, Heart Failure Society of A. Genetic evaluation of cardiomyopathy \u2013 a Heart Failure Society of America practice guideline. J Card Fail. 2009;15:83\u201397.","journal-title":"J Card Fail"},{"key":"1405_CR12","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.gde.2013.05.004","volume":"23","author":"S Yuan","year":"2013","unstructured":"Yuan S, Zaidi S, Brueckner M. Congenital heart disease: emerging themes linking genetics and development. Curr Opin Genet Dev. 2013;23:352\u20139.","journal-title":"Curr Opin Genet Dev"},{"key":"1405_CR13","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1093\/europace\/eup323","volume":"11","author":"MA Ohlow","year":"2009","unstructured":"Ohlow MA, Lauer B, Geller JC. Prevalence and spectrum of abnormal electrocardiograms in patients with an isolated congenital left ventricular aneurysm or diverticulum. Europace. 2009;11:1689\u201395.","journal-title":"Europace"},{"key":"1405_CR14","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1016\/j.jacc.2014.08.035","volume":"64","author":"F Zemrak","year":"2014","unstructured":"Zemrak F, Ahlman MA, Captur G, Mohiddin SA, Kawel-Boehm N, Prince MR, Moon JC, Hundley WG, Lima JA, Bluemke DA, Petersen SE. The relationship of left ventricular trabeculation to ventricular function and structure over a 9.5-year follow-up: the MESA study. J Am Coll Cardiol. 2014;64:1971\u201380.","journal-title":"J Am Coll Cardiol"},{"key":"1405_CR15","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ijcard.2009.07.003","volume":"140","author":"G Captur","year":"2010","unstructured":"Captur G, Nihoyannopoulos P. Left ventricular non-compaction: genetic heterogeneity, diagnosis and clinical course. Int J Cardiol. 2010;140:145\u201353.","journal-title":"Int J Cardiol"},{"key":"1405_CR16","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1161\/CIRCIMAGING.111.971713","volume":"5","author":"N Kawel","year":"2012","unstructured":"Kawel N, Nacif M, Arai AE, Gomes AS, Hundley WG, Johnson WC, Prince MR, Stacey RB, Lima JA, Bluemke DA. Trabeculated (noncompacted) and compact myocardium in adults: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Imaging. 2012;5:357\u201366.","journal-title":"Circ Cardiovasc Imaging"},{"key":"1405_CR17","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0735-1097(87)80383-2","volume":"9","author":"MT Boyd","year":"1987","unstructured":"Boyd MT, Seward JB, Tajik AJ, Edwards WD. Frequency and location of prominent left ventricular trabeculations at autopsy in 474 normal human hearts: implications for evaluation of mural thrombi by two-dimensional echocardiography. J Am Coll Cardiol. 1987;9:323\u20136.","journal-title":"J Am Coll Cardiol"},{"key":"1405_CR18","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1001\/jamainternmed.2014.7186","volume":"175","author":"S Gati","year":"2015","unstructured":"Gati S, Merghani A, Sharma S. Increased left ventricular trabeculation does not necessarily equate to left ventricular noncompaction in athletes. JAMA Intern Med. 2015;175:461\u20132.","journal-title":"JAMA Intern Med"},{"key":"1405_CR19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0167-5273(01)00598-8","volume":"82","author":"H Tikiz","year":"2002","unstructured":"Tikiz H, Atak R, Balbay Y, Genc Y, Kutuk E. Left ventricular aneurysm formation after anterior myocardial infarction: clinical and angiographic determinants in 809 patients. Int J Cardiol. 2002;82:7\u201314. discussion 14\u201316.","journal-title":"Int J Cardiol"},{"key":"1405_CR20","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1378\/chest.109.1.282","volume":"109","author":"A Frustaci","year":"1996","unstructured":"Frustaci A, Gentiloni N, Caldarulo M. Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus. Chest. 1996;109:282\u20134.","journal-title":"Chest"},{"key":"1405_CR21","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1093\/eurheartj\/ehm228","volume":"28","author":"M Pieroni","year":"2007","unstructured":"Pieroni M, Ferrante G, Crea F. Sawfish left ventricle: acute myocarditis presenting with left ventricular aneurysm. Eur Heart J. 2007;28:2567.","journal-title":"Eur Heart J"},{"key":"1405_CR22","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/ccd.10082","volume":"55","author":"PH McNulty","year":"2002","unstructured":"McNulty PH, Sun B, Naccarelli GV, Ettinger SM. Left ventricular aneurysm as a consequence of hypertrophic obstructive cardiomyopathy. Catheter Cardiovasc Interv. 2002;55:385\u20138.","journal-title":"Catheter Cardiovasc Interv"},{"key":"1405_CR23","first-page":"735","volume":"21","author":"H Nishikawa","year":"1991","unstructured":"Nishikawa H, Kasai A, Ono N, Unno M, Kakuta Y, Nishimura S, Nishiyama S, Nakanishi S, Seki A, Nakano T. Two cases of bi-ventricular dysplasia associated with ventricular tachycardia and familial occurrence of sudden death. J Cardiol. 1991;21:735\u201347.","journal-title":"J Cardiol"},{"key":"1405_CR24","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1136\/hrt.2003.031179","volume":"90","author":"SE Haine","year":"2004","unstructured":"Haine SE, Paelinck BP, Vrints CJ. Post-traumatic focal true left ventricular aneurysm. Heart. 2004;90:1009.","journal-title":"Heart"},{"key":"1405_CR25","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1378\/chest.118.6.1696","volume":"118","author":"A Frustaci","year":"2000","unstructured":"Frustaci A, Chimenti C, Pieroni M. Prognostic significance of left ventricular aneurysms with normal global function caused by myocarditis. Chest. 2000;118:1696\u2013702.","journal-title":"Chest"},{"key":"1405_CR26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0008-6363(03)00475-9","volume":"60","author":"F Calabrese","year":"2003","unstructured":"Calabrese F, Thiene G. Myocarditis and inflammatory cardiomyopathy: microbiological and molecular biological aspects. Cardiovasc Res. 2003;60:11\u201325.","journal-title":"Cardiovasc Res"},{"key":"1405_CR27","first-page":"316","volume":"21","author":"J Fu","year":"2007","unstructured":"Fu J, Yuan Y, Sun LP, Cui XD. Relation between acute respiratory infection and enterovirus in children in Beijing area. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2007;21:316\u20138.","journal-title":"Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi"},{"key":"1405_CR28","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1099\/jmm.0.068247-0","volume":"63","author":"QB Lu","year":"2014","unstructured":"Lu QB, Wo Y, Wang HY, Wei MT, Zhang L, Yang H, Liu EM, Li TY, Zhao ZT, Liu W, Cao WC. Detection of enterovirus 68 as one of the commonest types of enterovirus found in patients with acute respiratory tract infection in China. J Med Microbiol. 2014;63:408\u201314.","journal-title":"J Med Microbiol"},{"key":"1405_CR29","doi-asserted-by":"crossref","first-page":"e48409","DOI":"10.1371\/journal.pone.0048409","volume":"7","author":"O Cinek","year":"2012","unstructured":"Cinek O, Tapia G, Witso E, Kramna L, Holkova K, Rasmussen T, Stene LC, Ronningen KS. Enterovirus RNA in peripheral blood may be associated with the variants of rs1990760, a common type 1 diabetes associated polymorphism in IFIH1. PLoS One. 2012;7:e48409.","journal-title":"PLoS One"},{"key":"1405_CR30","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1086\/374742","volume":"187","author":"ME Craig","year":"2003","unstructured":"Craig ME, Howard NJ, Silink M, Rawlinson WD. Reduced frequency of HLA DRB1*03-DQB1*02 in children with type 1 diabetes associated with enterovirus RNA. J Infect Dis. 2003;187:1562\u201370.","journal-title":"J Infect Dis"},{"key":"1405_CR31","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1093\/eurheartj\/ehq493","volume":"32","author":"F Mahfoud","year":"2011","unstructured":"Mahfoud F, Gartner B, Kindermann M, Ukena C, Gadomski K, Klingel K, Kandolf R, Bohm M, Kindermann I. Virus serology in patients with suspected myocarditis: utility or futility? Eur Heart J. 2011;32:897\u2013903.","journal-title":"Eur Heart J"},{"key":"1405_CR32","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.jacc.2009.02.007","volume":"53","author":"MG Friedrich","year":"2009","unstructured":"Friedrich MG, Sechtem U, Schulz-Menger J, Holmvang G, Alakija P, Cooper LT, White JA, Abdel-Aty H, Gutberlet M, Prasad S, et al. Cardiovascular magnetic resonance in myocarditis: A JACC White Paper. J Am Coll Cardiol. 2009;53:1475\u201387.","journal-title":"J Am Coll Cardiol"},{"key":"1405_CR33","first-page":"382","volume":"54","author":"S Lv","year":"2013","unstructured":"Lv S, Rong J, Ren S, Wu M, Li M, Zhu Y, Zhang J. Epidemiology and diagnosis of viral myocarditis. Hellenic J Cardiol. 2013;54:382\u201391.","journal-title":"Hellenic J Cardiol"},{"key":"1405_CR34","first-page":"405","volume":"27","author":"Group on the countermeasures of myocarditis and cardiomyopathy of Editorial Committee of Chinese Journal of Cardiology","year":"1999","unstructured":"Group on the countermeasures of myocarditis and cardiomyopathy of Editorial Committee of Chinese Journal of Cardiology. About the diagnostic reference standard of adult acute viral myocarditis and adopt the suggestion for definition and classification of cardiomyopathy from the World Health Organization and the International Federation of Society of Cardiology Working Group. Chin J Cardiol. 1999;27:405\u20137.","journal-title":"Chin J Cardiol"},{"issue":"35","key":"1405_CR35","first-page":"2733","volume":"2014","author":"PM Elliott","year":"2014","unstructured":"Elliott PM, Anastasakis A, Borger MA, Borggrefe M, Cecchi F, Charron P, Hagege AA, Lafont A, Limongelli G, Mahrholdt H, et al. ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). Eur Heart J. 2014;2014(35):2733\u201379.","journal-title":"Eur Heart J"},{"key":"1405_CR36","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1161\/CIRCULATIONAHA.108.840827","volume":"121","author":"FI Marcus","year":"2010","unstructured":"Marcus FI, McKenna WJ, Sherrill D, Basso C, Bauce B, Bluemke DA, Calkins H, Corrado D, Cox MG, Daubert JP, et al. Diagnosis of arrhythmogenic right ventricular cardiomyopathy\/dysplasia: proposed modification of the task force criteria. Circulation. 2010;121:1533\u201341.","journal-title":"Circulation"},{"key":"1405_CR37","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ccm.2010.04.001","volume":"31","author":"SE Self","year":"2010","unstructured":"Self SE. Autoantibody testing for autoimmune disease. Clin Chest Med. 2010;31:415\u201322.","journal-title":"Clin Chest Med"},{"key":"1405_CR38","first-page":"525","volume":"32","author":"YH Xu","year":"1993","unstructured":"Xu YH, Gu YY, Yang HT. A study of anti-D\u2019E polypeptide in the diagnosis of mixed connective tissue disease. Zhonghua Nei Ke Za Zhi. 1993;32:525\u20137.","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"1405_CR39","doi-asserted-by":"crossref","first-page":"ITC4","DOI":"10.7326\/0003-4819-159-7-201310010-01004","volume":"159","author":"M Kiriakidou","year":"2013","unstructured":"Kiriakidou M, Cotton D, Taichman D, Williams S. Systemic lupus erythematosus. Ann Intern Med. 2013;159:ITC4\u20131.","journal-title":"Ann Intern Med"},{"key":"1405_CR40","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0735-1097(00)00755-5","volume":"36","author":"EN Oechslin","year":"2000","unstructured":"Oechslin EN, Attenhofer JCH, Rojas JR, Kaufmann PA, Jenni R. Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol. 2000;36:493\u2013500.","journal-title":"J Am Coll Cardiol"},{"key":"1405_CR41","doi-asserted-by":"crossref","first-page":"13615","DOI":"10.1074\/jbc.M114.550418","volume":"289","author":"X Lin","year":"2014","unstructured":"Lin X, Ruiz J, Bajraktari I, Ohman R, Banerjee S, Gribble K, Kaufman JD, Wingfield PT, Griggs RC, Fischbeck KH. Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy. J Biol Chem. 2014;289:13615.","journal-title":"J Biol Chem"},{"key":"1405_CR42","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1083\/jcb.146.2.465","volume":"146","author":"G Faulkner","year":"1999","unstructured":"Faulkner G, Pallavicini A, Formentin E, Comelli A, Ievolella C, Trevisan S, Bortoletto G, Scannapieco P, Salamon M, Mouly V. ZASP: a new Z-band alternatively spliced PDZ-motif protein. J Cell Biol. 1999;146:465\u201375.","journal-title":"J Cell Biol"},{"key":"1405_CR43","doi-asserted-by":"crossref","first-page":"13998","DOI":"10.1074\/jbc.M200712200","volume":"277","author":"N Frey","year":"2002","unstructured":"Frey N, Olson EN. Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins. J Biol Chem. 2002;277:13998.","journal-title":"J Biol Chem"},{"key":"1405_CR44","unstructured":"Online Mendelian Inheritance in Man. An Online Catalog of Human Genes and Genetic Disorders. \nhttp:\/\/omim.org\/entry\/605906\n\n. Accessed 3 Feb 2017."},{"key":"1405_CR45","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1016\/j.jacc.2003.10.021","volume":"42","author":"M Vatta","year":"2003","unstructured":"Vatta M, Mohapatra B, Jimenez S, Sanchez X, Faulkner G, Perles Z, Sinagra G, Lin JH, Vu TM, Zhou Q. Mutations in Cypher\/ZASP in Patients with Dilated Cardiomyopathy and Left Ventricular Non-Compaction. J Am Coll Cardiol. 2003;42:2014\u201327.","journal-title":"J Am Coll Cardiol"},{"key":"1405_CR46","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.bbrc.2006.10.119","volume":"351","author":"JL Theis","year":"2006","unstructured":"Theis JL, Bos JM, Bartleson VB, Will ML, Binder J, Vatta M, Towbin JA, Gersh BJ, Ommen SR, Ackerman MJ. Echocardiographic-determined septal morphology in Z-disc hypertrophic cardiomyopathy. Biochem Biophys Res Commun. 2006;351:896\u2013902.","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-017-1405-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T04:40:26Z","timestamp":1502426426000},"score":1,"resource":{"primary":{"URL":"http:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-017-1405-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,19]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1405"],"URL":"https:\/\/doi.org\/10.1186\/s13256-017-1405-1","relation":{},"ISSN":["1752-1947"],"issn-type":[{"type":"electronic","value":"1752-1947"}],"subject":[],"published":{"date-parts":[[2017,8,19]]},"article-number":"229"}}