{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:59:37Z","timestamp":1767851977520,"version":"3.49.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s13256-017-1467-0","type":"journal-article","created":{"date-parts":[[2017,10,18]],"date-time":"2017-10-18T08:17:36Z","timestamp":1508314656000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Primary small cell carcinoma of the breast: a case report"],"prefix":"10.1186","volume":"11","author":[{"given":"Iman","family":"Abou Dalle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaber","family":"Abbas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fouad","family":"Boulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad","family":"Salem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem I.","family":"Assi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,10,19]]},"reference":[{"key":"1467_CR1","first-page":"1369","volume":"20","author":"E L\u00f3pez-Bonet","year":"2008","unstructured":"L\u00f3pez-Bonet E, Alonso-Ruano M, Barraza G, Vazquez-Martin A, Bernad\u00f3 L, Menendez J. Solid neuroendocrine breast carcinomas: Incidence, clinico-pathological features and immunohistochemical profiling. Oncol Rep. 2008;20:1369\u201374.","journal-title":"Oncol Rep."},{"key":"1467_CR2","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/tbj.12121","volume":"19","author":"Y Zhu","year":"2013","unstructured":"Zhu Y, Li Q, Gao J, He Z, Sun R, Shen G, et al. Clinical features and treatment response of solid neuroendocrine breast carcinoma to adjuvant chemotherapy and endocrine therapy. Breast J. 2013;19:382\u20137.","journal-title":"Breast J."},{"key":"1467_CR3","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1111\/his.12463","volume":"66","author":"PH Tan","year":"2015","unstructured":"Tan PH, Schnitt SJ, van de Vijver MJ, Ellis IO, Lakhani SR. Papillary and neuroendocrine breast lesions: the WHO stance. Histopathology. 2015;66:761\u201370.","journal-title":"Histopathology."},{"key":"1467_CR4","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1155\/2014\/408459","volume":"2014","author":"DL Wachter","year":"2014","unstructured":"Wachter DL, Hartmann A, Beckmann MW, Fasching PA, Hein A, Bayer CM, et al. Expression of neuroendocrine markers in different molecular subtypes of breast carcinoma. Biomed Res Int. 2014;2014:408\u201359.","journal-title":"Biomed Res Int."},{"key":"1467_CR5","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1046\/j.1365-2559.2002.01336.x","volume":"40","author":"A Miremadi","year":"2002","unstructured":"Miremadi A, Pinder SE, Lee AH, Bell JA, Paish EC, Wencyk P, et al. Neuroendocrine differentiation and prognosis in breast adenocarcinoma. Histopathology. 2002;40:215\u201322.","journal-title":"Histopathology."},{"key":"1467_CR6","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.breast.2003.11.008","volume":"13","author":"C Krimpen van","year":"2004","unstructured":"van Krimpen C, Elferink A, Broodman CA, Hop WC, Pronk A, Menke M. The prognostic influence of neuroendocrine differentiation in breast cancer: results of a long-term follow-up study. Breast. 2004;13:329\u201333.","journal-title":"Breast."},{"key":"1467_CR7","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.breast.2013.11.005","volume":"23","author":"RW Adams","year":"2014","unstructured":"Adams RW, Dyson P, Barthelmes L. Neuroendocrine breast tumours: breast cancer or neuroendocrine cancer presenting in the breast? Breast. 2014;23:120\u20137.","journal-title":"Breast."},{"key":"1467_CR8","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1136\/jcp.2004.020792","volume":"58","author":"T Adegbola","year":"2005","unstructured":"Adegbola T, Connolly CE, Mortimer G. Small cell neuroendocrine carcinoma of the breast: a report of three cases and review of the literature. J Clin Pathol. 2005;58:775\u20138.","journal-title":"J Clin Pathol."},{"key":"1467_CR9","first-page":"354","volume":"31","author":"QD Ge","year":"2012","unstructured":"Ge QD, Lv N, Cao Y, Wang X, Tang J, Xie ZM, et al. A case report of primary small cell carcinoma of the breast and review of the literature. Chin J Cancer. 2012;31:354\u20138.","journal-title":"Chin J Cancer."},{"key":"1467_CR10","doi-asserted-by":"crossref","first-page":"663","DOI":"10.2147\/OTT.S60782","volume":"7","author":"J Jiang","year":"2014","unstructured":"Jiang J, Wang G, Lv L, Liu C, Liang X, Zhao H. Primary small-cell neuroendocrine carcinoma of the male breast: a rare case report with review of the literature. Onco Targets Ther. 2014;7:663\u20136.","journal-title":"Onco Targets Ther."},{"key":"1467_CR11","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1097\/00000478-200009000-00006","volume":"24","author":"SJ Shin","year":"2000","unstructured":"Shin SJ, DeLellis RA, Ying L, Rosen PP. Small cell carcinoma of the breast: a clinicopathologic and immunohistochemical study of nine patients. Am J Surg Pathol. 2000;24:1231\u20138.","journal-title":"Am J Surg Pathol."},{"key":"1467_CR12","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s40064-015-0913-y","volume":"4","author":"F Hare","year":"2015","unstructured":"Hare F, Giri S, Patel JK, Hahn A, Martin MG. A population-based analysis of outcomes for small cell carcinoma of the breast by tumor stage and the use of radiation therapy. Springerplus. 2015;4:138.","journal-title":"Springerplus."},{"key":"1467_CR13","first-page":"186","volume":"120","author":"G Bussolati","year":"1985","unstructured":"Bussolati G, Gugliotta P, Sapino A, Eusebi V, Lloyd RV. Chromogranin-reactive endocrine cells in argyrophilic carcinomas (\u201ccarcinoids\u201d) and normal tissue of the breast. Am J Pathol. 1985;120:186\u201392.","journal-title":"Am J Pathol."},{"issue":"Suppl 1","key":"1467_CR14","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S1743-9191(13)60023-0","volume":"11","author":"F Rovera","year":"2013","unstructured":"Rovera F, Lavazza M, Rosa SL, Fachinetti A, Chiappa C, Marelli M, et al. Neuroendocrine breast cancer: retrospective analysis of 96 patients and review of literature. Int J Surg. 2013;11 Suppl 1:79\u201383.","journal-title":"Int J Surg."},{"key":"1467_CR15","doi-asserted-by":"crossref","first-page":"4463","DOI":"10.1002\/cncr.25352","volume":"116","author":"B Wei","year":"2010","unstructured":"Wei B, Ding T, Xing Y, Wei W, Tian Z, Tang F, et al. Invasive neuroendocrine carcinoma of the breast: a distinctive subtype of aggressive mammary carcinoma. Cancer. 2010;116:4463\u201373.","journal-title":"Cancer."},{"key":"1467_CR16","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.canrad.2015.04.003","volume":"19","author":"J Feki","year":"2015","unstructured":"Feki J, Fourati N, Mnif H, Khabir A, Toumi N, Khanfir A, et al. Primary neuroendocrine tumors of the breast: a retrospective study of 21 cases and literature review. Cancer Radiother. 2015;19:308\u201312.","journal-title":"Cancer Radiother."},{"issue":"Suppl 2","key":"1467_CR17","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/annonc\/12.suppl_2.S115","volume":"12","author":"A Sapino","year":"2001","unstructured":"Sapino A, Papotti M, Righi L, Cassoni P, Chiusa L, Bussolati G. Clinical significance of neuroendocrine carcinoma of the breast. Ann Oncol. 2001;12 Suppl 2:115\u20137.","journal-title":"Ann Oncol."},{"key":"1467_CR18","first-page":"691","volume":"23","author":"G Bigotti","year":"2004","unstructured":"Bigotti G, Coli A, Butti A, del Vecchio M, Tartaglione R, Massi G. Primary small cell neuroendocrine carcinoma of the breast. J Exp Clin Cancer Res. 2004;23:691\u20136.","journal-title":"J Exp Clin Cancer Res."},{"key":"1467_CR19","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.humpath.2010.11.014","volume":"42","author":"Z Tian","year":"2011","unstructured":"Tian Z, Wei B, Tang F, Wei W, Gilcrease MZ, Huo L, et al. Prognostic significance of tumor grading and staging in mammary carcinomas with neuroendocrine differentiation. Hum Pathol. 2011;42:1169\u201377.","journal-title":"Hum Pathol."},{"key":"1467_CR20","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s10549-016-3867-z","volume":"158","author":"B McCullar","year":"2016","unstructured":"McCullar B, Pandey M, Yaghmour G, Hare F, Patel K, Stein M, et al. Genomic landscape of small cell carcinoma of the breast contrasted to small cell carcinoma of the lung. Breast Cancer Res Treat. 2016;158:195\u2013202.","journal-title":"Breast Cancer Res Treat."},{"key":"1467_CR21","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/path.2407","volume":"216","author":"B Weigelt","year":"2008","unstructured":"Weigelt B, Horlings HM, Kreike B, Hayes MM, Hauptmann M, Wessels LF, et al. Refinement of breast cancer classification by molecular characterization of histological special types. J Pathol. 2008;216:141\u201350.","journal-title":"J Pathol."},{"key":"1467_CR22","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1634\/theoncologist.2015-0309","volume":"21","author":"A Inno","year":"2016","unstructured":"Inno A, Bogina G, Turazza M, Bortesi L, Duranti S, Massocco A, et al. Neuroendocrine carcinoma of the breast: current evidence and future perspectives. Oncologist. 2016;21:28\u201332.","journal-title":"Oncologist."},{"key":"1467_CR23","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.breast.2004.06.007","volume":"13","author":"A Berruti","year":"2004","unstructured":"Berruti A, Saini A, Leonardo E, Cappia S, Borasio P, Dogliotti L. Management of neuroendocrine differentiated breast carcinoma. Breast. 2004;13:527\u20139.","journal-title":"Breast."},{"key":"1467_CR24","first-page":"887","volume":"2","author":"Y Yildirim","year":"2011","unstructured":"Yildirim Y, Elagoz S, Koyuncu A, Aydin C, Karadayi K. Management of neuroendocrine carcinomas of the breast: A rare entity. Oncol Lett. 2011;2:887\u201390.","journal-title":"Oncol Lett."},{"key":"1467_CR25","first-page":"5079","volume":"32","author":"R Watrowski","year":"2012","unstructured":"Watrowski R, Jager C, Mattern D, Horst C. Neuroendocrine carcinoma of the breast--diagnostic and clinical implications. Anticancer Res. 2012;32:5079\u201382.","journal-title":"Anticancer Res."},{"key":"1467_CR26","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.1524-4741.2010.00974.x","volume":"16","author":"N Latif","year":"2010","unstructured":"Latif N, Rosa M, Samian L, Rana F. An unusual case of primary small cell neuroendocrine carcinoma of the breast. Breast J. 2010;16:647\u201351.","journal-title":"Breast J."}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-017-1467-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,18]],"date-time":"2017-10-18T08:17:42Z","timestamp":1508314662000},"score":1,"resource":{"primary":{"URL":"http:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-017-1467-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,19]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1467"],"URL":"https:\/\/doi.org\/10.1186\/s13256-017-1467-0","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,19]]},"article-number":"290"}}