{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:14:32Z","timestamp":1740147272205,"version":"3.37.3"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T00:00:00Z","timestamp":1572307200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T00:00:00Z","timestamp":1572307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n              <jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Infertility continues to be an enigmatic and emerging problem. Although <jats:italic>in vitro<\/jats:italic> fertilization has proved to be revolutionary and immensely beneficial to many people, it is far from perfect, and many women experience recurrent <jats:italic>in vitro<\/jats:italic> fertilization failures. There can be a multitude of factors involved in recurrent <jats:italic>in vitro<\/jats:italic> fertilization failures. The aim of this report was to explore the role of hysteroscopy in determining potential causes of <jats:italic>in vitro<\/jats:italic> fertilization failure and how the relevant hysteroscopic findings can address the issue of infertility in terms of a subsequent successful <jats:italic>in vitro<\/jats:italic> fertilization.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 37-year-old white Arab woman with a history of eight <jats:italic>in vitro<\/jats:italic> fertilization failures and one curettage performed for a blighted ovum presented to our hospital because of inability to conceive. Her past medical history was significant for hypothyroidism and positive factor V Leiden. She underwent hystero contrast sonography, which revealed a normal uterine cavity with irregular fillings in the right corner. To explore this further, hysteroscopy was performed, which showed dense adhesions in the right upper corner and first-degree adhesions in the lower half of the uterus. After undergoing adhesiolysis and a cycle of estradiol valerate and progesterone, the patient successfully conceived twins.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Hysteroscopy may play an important role before or in conjunction with assisted reproductive techniques to help infertile women and couples achieve their goals of pregnancy and live birth of a child.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-019-2247-9","type":"journal-article","created":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T20:44:07Z","timestamp":1572468247000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful pregnancy for primary amenorrhea and recurrent implantation failure and the role of hysteroscopic adhesiolysis: a case report"],"prefix":"10.1186","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6870-7019","authenticated-orcid":false,"given":"Zakwan","family":"Khrait","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,10,29]]},"reference":[{"issue":"5","key":"2247_CR1","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/j.fertnstert.2012.03.017","volume":"97","author":"AS Penzias","year":"2012","unstructured":"Penzias AS. Recurrent IVF failure: other factors. Fertil Steril. 2012;97(5):1033\u20138.","journal-title":"Fertil Steril"},{"key":"2247_CR2","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1046\/j.1469-0705.1997.10010059.x","volume":"10","author":"G Ayida","year":"1997","unstructured":"Ayida G, Chamberlain P, Barlow D, Kennedy S. Uterine cavity assessment prior to in vitro fertilization: comparison of transvaginal scanning, saline contrast hysterosonography and hysteroscopy. Ultrasound Obstet Gynecol. 1997;10:59\u201362.","journal-title":"Ultrasound Obstet Gynecol"},{"key":"2247_CR3","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1016\/S1472-6483(10)61108-X","volume":"8","author":"A Demirol","year":"2004","unstructured":"Demirol A, Gurgan T. Effect of treatment of intrauterine pathologies with office hysteroscopy in patients with recurrent IVF failure. 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Results of in vitro fertilization for endometriosis. Contrib Gynecol Obstet. 1987;16:328\u201331.","journal-title":"Contrib Gynecol Obstet"},{"issue":"2","key":"2247_CR11","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/s00404-012-2627-5","volume":"287","author":"P Cenksoy","year":"2013","unstructured":"Cenksoy P, Ficicioglu C, Y\u0131ld\u0131r\u0131m G, Yesiladali M. Hysteroscopic findings in women with recurrent IVF failures and the effect of correction of hysteroscopic findings on subsequent pregnancy rates. Arch Gynecol Obstet. 2013;287(2):357\u201360.","journal-title":"Arch Gynecol Obstet"},{"key":"2247_CR12","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1056\/NEJMoa1808737","volume":"380","author":"S Lensen","year":"2019","unstructured":"Lensen S, Wilkinson J, Sadler L. A randomized trial of endometrial scratching before in vitro fertilization [letter]. 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No animals were involved or harmed in the study.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The author declares that he has no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"321"}}