{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T17:05:34Z","timestamp":1792861534868,"version":"4.5.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,3,28]],"date-time":"2021-03-28T00:00:00Z","timestamp":1616889600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,3,28]],"date-time":"2021-03-28T00:00:00Z","timestamp":1616889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Vulvar Paget\u2019s disease (VPD) is a rare malignant disorder originating in the external genitalia. It occasionally invades into urethral or vaginal mucosa of female, making surgical treatment more complicating. In case of urethral invasion of Paget\u2019s cells, systematic mapping biopsy of urethral mucosa is the standard of care to determine the range of surgical resection. Resection of urethral mucosa and simple skin grafting often result in urethral stricture after surgery, which severely deteriorates patient\u2019s quality of life.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We applied a new technique of advancement urethral meatoplasty using buccal mucosa, in two Japanese cases of VPD with urethral invasion. After broad resection of vulvar skin together with the urethral mucosa, buccal mucosa was implanted between advanced urethral mucosa and skin graft. In both cases, we could prevent urethral stricture one year and two years after surgery, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This technique prevented urethral stricture after surgery and could be a useful technique as part of urethroplasty for VPD.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-02729-1","type":"journal-article","created":{"date-parts":[[2021,3,28]],"date-time":"2021-03-28T00:02:57Z","timestamp":1616889777000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Novel operative technique of advancement urethral meatoplasty utilizing buccal mucosa for Vulvar Paget\u2019s disease with urethral invasion: two\u00a0case reports"],"prefix":"10.1186","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7473-3325","authenticated-orcid":false,"given":"Masaki","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Hakozaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohei","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Makino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taketo","family":"Kawai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motofumi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Omatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanobu","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuto","family":"Hoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruki","family":"Kume","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiko","family":"Igawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,28]]},"reference":[{"key":"2729_CR1","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.critrevonc.2016.03.008","volume":"101","author":"M van der Linden","year":"2016","unstructured":"van der Linden M, Meeuwis KA, Bulten J, Bosse T, van Poelgeest MI, de Hullu JA. Paget disease of the vulva. Crit Rev Oncol Hematol. 2016;101:60\u201374.","journal-title":"Crit Rev Oncol Hematol."},{"issue":"8","key":"2729_CR2","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1111\/j.1442-2042.2004.00870.x","volume":"11","author":"T Chin","year":"2004","unstructured":"Chin T, Murakami M, Hyakusoku H. Extramammary Paget\u2019s disease of the vulva subclinically extending to the bladder neck: correct staging obtained with endoscopic urethral biopsy. Int J Urol. 2004;11(8):689\u201391.","journal-title":"Int J Urol."},{"issue":"1","key":"2729_CR3","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.ucl.2010.12.008","volume":"38","author":"N Rosenblum","year":"2011","unstructured":"Rosenblum N, Nitti VW. Female urethral reconstruction. Urol Clin North Am. 2011;38(1):55\u201364, vi.","journal-title":"Urol Clin North Am."},{"issue":"6","key":"2729_CR4","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1016\/j.urology.2011.01.017","volume":"77","author":"FF Onol","year":"2011","unstructured":"Onol FF, Antar B, Kose O, Erdem MR, Onol SY. Techniques and results of urethroplasty for female urethral strictures: our experience with 17 patients. Urology. 2011;77(6):1318\u201324.","journal-title":"Urology."},{"issue":"5","key":"2729_CR5","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.urology.2005.12.010","volume":"67","author":"RK Berglund","year":"2006","unstructured":"Berglund RK, Vasavada S, Angermeier K, Rackley R. Buccal mucosa graft urethroplasty for recurrent stricture of female urethra. Urology. 2006;67(5):1069\u201371.","journal-title":"Urology."},{"issue":"1","key":"2729_CR6","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.urpr.2016.02.002","volume":"4","author":"CR Powell","year":"2017","unstructured":"Powell CR, Daniels D. Dorsal onlay buccal urethroplasty in the female is associated with high quality of life using validated lower urinary tract symptom instruments. Urol Pract. 2017;4(1):48\u201353.","journal-title":"Urol Pract."},{"key":"2729_CR7","volume-title":"General rules for clinical and pathological studies on malignant neoplasms of the skin","author":"The Japanese Skin Cancer Society","year":"2002","unstructured":"The Japanese Skin Cancer Society. General rules for clinical and pathological studies on malignant neoplasms of the skin. 1st ed. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no conflict of interest to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"136"}}