{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T08:49:33Z","timestamp":1775638173021,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Hidradenoma papilliferum is a rare benign neoplasm arising from apocrine glands. It occurs commonly on the anogenital region of middle-aged women. It usually presents as a slow growing, solitary asymptomatic, skin colored or red nodule less than 1 cm in diameter.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>The case is a 38-year-old, white woman who presented with a painful nodule occurring within a month in the himenal region of the posterior vaginal introitus. The nodule was excisied and the histology revealed a hidradenoma papilliferum. The diagnosis and treatment of hidradenoma papilliferum is possible with surgical removal and histopathological evaluation of nodules.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>When an adult woman presents with a noduler lesion in the anogenital area, sexually transmitted diseases and other benign and malignant vulvar lesions, as well as malignant transformation is very rare but,should be kept in mind; however because it has been reported and long-term clinical follow-up is suggested<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-02786-6","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T23:04:22Z","timestamp":1618268662000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Hidradenoma papilliferum of the hymen: a case report"],"prefix":"10.1186","volume":"15","author":[{"given":"Ozer","family":"Birge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Sait","family":"Bak\u0131r","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ceyda","family":"Karadag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zivar","family":"Eldarova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayup","family":"Simsek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"key":"2786_CR1","doi-asserted-by":"publisher","first-page":"S20","DOI":"10.1067\/mjd.2003.125","volume":"48","author":"M Tanaka","year":"2003","unstructured":"Tanaka M, Shimizu S. Hidradenoma papilliferum occurring on the chest of a man. J Am Acad Dermatol. 2003;48:S20\u20131.","journal-title":"J Am Acad Dermatol"},{"key":"2786_CR2","first-page":"616","volume":"45","author":"A Virgili","year":"2000","unstructured":"Virgili A, Marzola A, Corazza M. Vulvar hidradenoma papilliferum. A review of 10.5-year\u2019s experience. J Reprod Med. 2000;45:616\u20138.","journal-title":"J Reprod Med"},{"key":"2786_CR3","first-page":"790","volume":"29","author":"Y Handa","year":"2003","unstructured":"Handa Y, Yamanaka N, Inagaki H, Tomita Y. Large ulcerated perianal hidradenoma papilliferum in a young female. Dermatol Surg. 2003;29:790\u20132.","journal-title":"Dermatol Surg"},{"key":"2786_CR4","doi-asserted-by":"publisher","first-page":"153","DOI":"10.4048\/jbc.2011.14.2.153","volume":"14","author":"YJ Kim","year":"2011","unstructured":"Kim YJ, Lee JW, Choi SJ, Kim SJ, Kim YJ, Jeon YS, et al. Ectopic hidradenoma papilliferum of the breast: ultrasound finding. 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J Am Acad Dermatol. 1999;41:115\u20138.","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"2786_CR7","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1111\/ced.13669","volume":"44","author":"V Alegr\u00eda-Landa","year":"2019","unstructured":"Alegr\u00eda-Landa V, Jo-Velasco M, Requena L. Perianal nodule in a young woman. Clin Exp Dermatol. 2019;44(1):96\u20138.","journal-title":"Clin Exp Dermatol"},{"issue":"8\u20139","key":"2786_CR8","first-page":"537","volume":"146","author":"Spindler L, Pommaret E, Barracco MM, Fathallah N, Plantier F, Duchatelle, de Parades V","year":"2019","unstructured":"Spindler L, Pommaret E, Barracco MM, Fathallah N, Plantier F, Duchatelle, de Parades V. Anal and vulvar hidradenoma papilliferum are similar: a study of 14 cases. Ann Dermatol Venereol. 2019;146(8\u20139):537\u201341.","journal-title":"Ann Dermatol Venereol"},{"issue":"5","key":"2786_CR9","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1080\/01443615.2017.1284186","volume":"37","author":"C Hern\u00e1ndez-Angeles","year":"2017","unstructured":"Hern\u00e1ndez-Angeles C, Nadal A, Castelo-Branco C. Hidradenoma papilliferum of the vulva in a postpartum woman: a case report. J Obstet Gynaecol. 2017;37(5):683\u20134.","journal-title":"J Obstet Gynaecol"},{"key":"2786_CR10","doi-asserted-by":"publisher","first-page":"7","DOI":"10.5826\/dpc.0603a03","volume":"6","author":"G Theodosiou","year":"2016","unstructured":"Theodosiou G, Zafeiriadou V, Papageorgiou M, Mandekou-Lefaki I. An unusual lesion in the right place. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"162"}}