{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:12:52Z","timestamp":1777363972978,"version":"3.51.4"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T00:00:00Z","timestamp":1622160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T00:00:00Z","timestamp":1622160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Hydatid cysts are fluid-filled sacs containing immature forms of parastic tapeworms of the genus <jats:italic>Echinococcus<\/jats:italic>. The most prevalent and serious complication of hydatid disease is intrabiliary rupture, also known as cystobiliary fistulae. In this study, a sporadic case of biliary obstruction, cholangitis, and septicemia is described secondary to hydatid cyst rupture into the common bile duct and intraperitoneal cavity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 21-year-old Iranian man was admitted to the emergency ward with 5 days of serious sickness and a history of right upper quadrant abdominal pain, fatigue, fever, icterus, vomiting, and no appetite. In the physical examination, abdominal tenderness was detected in all four quadrants and in the scleral icterus. Abdominal ultrasound revealed intrahepatic and extrahepatic biliary duct dilation. Gallbladder wall thickening was normal but was very dilated, and large unilocular intact hepatic cysts were detected in segment IV and another one segment II which had detached laminated membranes and was a ruptured or complicated liver cyst.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Intrabiliary perforation of the liver hydatid cyst is an infrequent event but has severe consequences. Therefore, when patients complain of abdominal pain, fever, peritonitis, decreased appetite, and jaundice, a differential diagnosis of hydatid disease needs to be taken into consideration. Early diagnosis of complications and aggressive treatments, such as endoscopic retrograde cholangiopancreatography and surgery, are vital.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-02822-5","type":"journal-article","created":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T15:07:02Z","timestamp":1622214422000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Intrabiliary and abdominal rupture of hepatic hydatid cyst leading to biliary obstruction, cholangitis, pancreatitis, peritonitis and septicemia: a case report"],"prefix":"10.1186","volume":"15","author":[{"given":"Manouchehr","family":"Aghajanzadeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Taghi","family":"Ashoobi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Hemmati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pirooz","family":"Samidoust","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Sadegh Esmaeili","family":"Delshad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousha","family":"Pourahmadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,28]]},"reference":[{"key":"2822_CR1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3126\/ijls.v8i4.10893","volume":"8","author":"M Aghajanzadeh","year":"2014","unstructured":"Aghajanzadeh M, Asgary MR, Foumani AA, Alavi SE, Rimaz S, Banihashemi Z, et al. Surgical management of pleural complications of lung and liver hydatid cysts in 34 patients. Int J Life Sci. 2014;8:15\u20139.","journal-title":"Int J Life Sci"},{"key":"2822_CR2","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1177\/021849230801600510","volume":"16","author":"M Aghajanzadeh","year":"2008","unstructured":"Aghajanzadeh M, Safarpoor F, Amani H, Alavi A. One-stage procedure for lung and liver hydatid cysts. Asian Cardiovasc Thorac Ann. 2008;16:392\u20135.","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"2822_CR3","first-page":"245","volume":"13","author":"Z Sp\u00e2rchez","year":"2004","unstructured":"Sp\u00e2rchez Z, Osian G, Onica A, B\u0103rb\u00e2nt\u0103 C, Tan\u0163\u0103u M, Pascu O. Ruptured hydatid cyst of the liver with biliary obstruction: presentation of a case and review of the literature. Rom J Gastroenterol. 2004;13:245\u201350.","journal-title":"Rom J Gastroenterol"},{"key":"2822_CR4","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1001\/archsurg.136.11.1249","volume":"136","author":"M Atli","year":"2001","unstructured":"Atli M, Kama NA, Yuksek YN, Doganay M, Gozalan U, Kologlu M, et al. Intrabiliary rupture of a hepatic hydatid cyst: associated clinical factors and proper management. Arch Surg. 2001;136:1249\u201355.","journal-title":"Arch Surg"},{"key":"2822_CR5","doi-asserted-by":"publisher","first-page":"6455","DOI":"10.1186\/1757-1626-2-6455","volume":"2","author":"S Avcu","year":"2009","unstructured":"Avcu S, \u00dcnal \u00d6, Arslan H. Intrabiliary rupture of liver hydatid cyst: a case report and review of the literature. Cases J. 2009;2:6455.","journal-title":"Cases J"},{"key":"2822_CR6","first-page":"81","volume":"23","author":"HE S\u0131kar","year":"2017","unstructured":"S\u0131kar HE, Kaptano\u011flu L, Kement M. An unusual appearance of complicated hydatid cyst: necrotizing pancreatitis. Ulus Travma Acil Cerrahi Derg. 2017;23:81\u20133.","journal-title":"Ulus Travma Acil Cerrahi Derg"},{"key":"2822_CR7","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/0720-048X(90)90099-W","volume":"11","author":"WN von Sinner","year":"1990","unstructured":"von Sinner WN. Ultrasound, CT and MRI of ruptured and disseminated hydatid cysts. Eur J Radiol. 1990;11:31\u20137.","journal-title":"Eur J Radiol"},{"key":"2822_CR8","doi-asserted-by":"publisher","first-page":"15253","DOI":"10.3748\/wjg.v20.i41.15253","volume":"20","author":"K Dolay","year":"2014","unstructured":"Dolay K, Akbulut S. Role of endoscopic retrograde cholangiopancreatography in the management of hepatic hydatid disease. World J Gastroenterol. 2014;20:15253\u201361.","journal-title":"World J Gastroenterol"},{"key":"2822_CR9","doi-asserted-by":"publisher","first-page":"W84","DOI":"10.2214\/AJR.07.2068","volume":"189","author":"A Erden","year":"2007","unstructured":"Erden A, Ormeci N, Fitoz S, Erden I, Tanju S, Gen\u00e7 Y. Intrabiliary rupture of hepatic hydatid cysts: diagnostic accuracy of MR cholangiopancreatography. AJR Am J Roentgenol. 2007;189:W84\u20139.","journal-title":"AJR Am J Roentgenol"},{"key":"2822_CR10","doi-asserted-by":"publisher","first-page":"e15","DOI":"10.1016\/j.jemermed.2017.09.009","volume":"54","author":"F Ufuk","year":"2018","unstructured":"Ufuk F, Duran M. Intrabiliary rupture of hepatic hydatid cyst leading to biliary obstruction, cholangitis, and septicemia. J Emerg Med. 2018;54:e15\u20137.","journal-title":"J Emerg Med"},{"key":"2822_CR11","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1002\/bjs.1800770940","volume":"77","author":"M Akoglu","year":"1990","unstructured":"Akoglu M, Hilmioglu F, Balay AR, Sahin B, Davidson BR. Endoscopic sphincterotomy in hepatic hydatid disease open to the biliary tree. Br J Surg. 1990;77:1073.","journal-title":"Br J Surg"},{"key":"2822_CR12","first-page":"55","volume":"24","author":"S Agarwal","year":"2005","unstructured":"Agarwal S, Sikora SS, Kumar A, Saxena R, Kapoor VK. Bile leaks following surgery for hepatic hydatid disease. Indian J Gastroenterol. 2005;24:55\u20138.","journal-title":"Indian J Gastroenterol"},{"key":"2822_CR13","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1001\/archsurg.1980.01380070035007","volume":"115","author":"I Sayek","year":"1980","unstructured":"Sayek I, Yalin R, Sana\u00e7 Y. Surgical treatment of hydatid disease of the liver. Arch Surg. 1980;115:847\u201350.","journal-title":"Arch Surg"},{"key":"2822_CR14","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/S0001-706X(02)00217-6","volume":"85","author":"J El-On","year":"2003","unstructured":"El-On J. Benzimidazole treatment of cystic echinococcosis. Acta Trop. 2003;85:243\u201352.","journal-title":"Acta Trop"},{"key":"2822_CR15","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/S0001-706X(96)00640-7","volume":"64","author":"RJ Horton","year":"1997","unstructured":"Horton RJ. Albendazole in treatment of human cystic echinococcosis: 12 years of experience. Acta Trop. 1997;64:79\u201393.","journal-title":"Acta Trop"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-02822-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-021-02822-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-02822-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T15:09:31Z","timestamp":1622214571000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-021-02822-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,28]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["2822"],"URL":"https:\/\/doi.org\/10.1186\/s13256-021-02822-5","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,28]]},"assertion":[{"value":"21 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Ethics Committee of Guilan University of Medical Sciences approved the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"311"}}