{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:14:46Z","timestamp":1740147286025,"version":"3.37.3"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T00:00:00Z","timestamp":1620777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T00:00:00Z","timestamp":1620777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Brown-S\u00e9quard syndrome often occurs in spinal cord injury, and few myelitis patients present with Brown-S\u00e9quard syndrome.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 33-year-old  Han man was admitted with neck pain plus numbness in the right limbs for 2 days and weakness in the left limbs for 1 day. Examination was significant for left limbs with grade 4 muscle power, positive left Babinski sign, diminished vibration sensation in the left limbs and decreased pain below the right clavicle dermatome. The cerebrospinal fluid (CSF) cell count was 24\u2009\u00d7\u200910<jats:sup>6<\/jats:sup>\/L, and the protein count was 185\u00a0mg\/L. Cervical magnetic resonance imaging (MRI) indicated abnormal swelling signals in the medulla-cervical cord long segment and enhanced signals in the C2-3 region. In the second case, a 47-year-old Han woman was admitted with weakness in the right lower limb and numbness in the left lower limb for more than 20\u00a0days. Examination was significant for the right lower limb with grade 4 muscle power, left knee hyperreflexia, positive left Babinski sign, diminished vibration sensation in the right lower limb and decreased pain below the right T2 dermatome. Cervical MRI indicated hyperintense and enhanced signals in the C7-T2 region. In these two cases, CSF culture, oligoclonal band (OB)  and aquaporin 4 (AQP4) antibody\u00a0were negative. Brain MRI was normal. Their symptoms and MRI results improved after treatment with methylprednisolone.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Myelitis can present as Brown-S\u00e9quard syndrome, providing an extended reference in terms of the differential diagnosis for clinical physicians.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-02834-1","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T23:21:42Z","timestamp":1620775302000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Idiopathic myelitis presenting as Brown-S\u00e9quard syndrome: two case reports and a review of the\u00a0literature"],"prefix":"10.1186","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5020-2792","authenticated-orcid":false,"given":"Xi","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0606-561X","authenticated-orcid":false,"given":"Liang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,12]]},"reference":[{"key":"2834_CR1","volume-title":"Brown Sequard Syndrome","author":"S Shams","year":"2019","unstructured":"Shams S, Arain A. 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J Family Med Prim Care. 2019;8(6):2161\u20134.","journal-title":"J Family Med Prim Care"},{"issue":"5","key":"2834_CR11","doi-asserted-by":"publisher","first-page":"282","DOI":"10.5692\/clinicalneurol.cn-001261","volume":"59","author":"M Yamamoto","year":"2019","unstructured":"Yamamoto M, Satoi H, Matsumoto S. Acute myelitis with Brown-Sequard syndrome complicated with subjective sudomotor laterality and ileocecal abscess without right abdominal pain. 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The patient approved participation in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patients for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"233"}}