{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:34:13Z","timestamp":1767832453472,"version":"3.49.0"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T00:00:00Z","timestamp":1627948800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T00:00:00Z","timestamp":1627948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Epignathus is a rare, benign, congenital teratoma of the hard palate with an estimated incidence of 1 in 200,000 live births. Epignathus frequently leads to a high mortality (80\u2013100%) due to airway obstruction in the neonatal period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>We report a case of successful management of a rare oropharyngeal teratoma in a African newborn girl who was referred to our institute with a large protruding intraoral mass, combined with cleft palate, causing some respiratory compromise. The palatal mass was removed on the fifth day after birth, and a palatoplasty performed on day 30.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Epignathus is a life-threatening condition at the time of delivery. Appropriate management begins with securing the airway, followed by complete resection of the tumor.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s13256-021-03007-w","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T03:42:33Z","timestamp":1627962153000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Congenital epignathus associated with a cleft palate: a case report"],"prefix":"10.1186","volume":"15","author":[{"given":"Fabrice","family":"Lele Mutombo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Nzanzu Kikuhe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"No\u00e9","family":"Kasereka Mwanamolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc H.","family":"Erickson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Wetzig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e9dard","family":"Kabuyaya Kakule","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,8,3]]},"reference":[{"issue":"2","key":"3007_CR1","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1051\/mbcb\/2011109","volume":"17","author":"M Omezzine","year":"2011","unstructured":"Omezzine M, Bouslama S, Nouri S, Moatamri R, Khochtali H. Tumeurs cong\u00e9nitales de la cavit\u00e9 buccale et fente palatine: pr\u00e9sentation de 2 cas. Med Buccale Chir Buccale. 2011;17(2):167\u20139. https:\/\/doi.org\/10.1051\/mbcb\/2011109.","journal-title":"Med Buccale Chir Buccale"},{"issue":"251","key":"3007_CR2","doi-asserted-by":"crossref","first-page":"2013008735","DOI":"10.1136\/bcr-2013-008735","volume":"2013","author":"V Kundal","year":"2013","unstructured":"Kundal V, Gajdhar M, Sharma C, Kundal R. Intraoral teratoma in a newborn presenting as severe respiratory distress. BMJ Case Rep. 2013;2013(251):2013008735\u20132013008735.","journal-title":"BMJ Case Rep"},{"issue":"4","key":"3007_CR3","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1051\/mbcb\/2012039","volume":"18","author":"M Meziane","year":"2012","unstructured":"Meziane M, Eabdenbitsen A, Boulaadas M, Essakalli L, Kzadri M. Double t\u00e9ratome de la cavit\u00e9 buccale? Med Buccale Chir Buccale. 2012;18(4):383\u20135. https:\/\/doi.org\/10.1051\/mbcb\/2012039.","journal-title":"Med Buccale Chir Buccale"},{"issue":"1","key":"3007_CR4","doi-asserted-by":"publisher","first-page":"e97","DOI":"10.1097\/SCS.0b013e3182798f25","volume":"24","author":"A Al-Mahdi","year":"2013","unstructured":"Al-Mahdi A, Al-Khurrhi LE, Atto GZ, Dhaher A. Giant epignathus teratoma involving the palate, tongue, and floor of the mouth. J Craniofac Surg. 2013;24(1):e97\u20139.","journal-title":"J Craniofac Surg"},{"key":"3007_CR5","doi-asserted-by":"publisher","DOI":"10.5935\/1676-2444.20150055","author":"MP Menezes Filho","year":"2015","unstructured":"Menezes Filho MP, Simao NMMS. Giant epignathus of the palate: a case report. J Bras Patol Med Lab. 2015. https:\/\/doi.org\/10.5935\/1676-2444.20150055.","journal-title":"J Bras Patol Med Lab"},{"issue":"1","key":"3007_CR6","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1186\/s13000-018-0776-y","volume":"13","author":"M Kirishima","year":"2018","unstructured":"Kirishima M, Yamada S, Shinya M, Onishi S, Goto Y, Kitazono I, Hiraki T, Higashi M, Hida AI, Tanimoto A. An autopsy case of epignathus (immature teratoma of the soft palate) with intracranial extension but without brain invasion: case report and literature review. Diagn Pathol. 2018;13(1):99.","journal-title":"Diagn Pathol"},{"key":"3007_CR7","doi-asserted-by":"publisher","first-page":"2809","DOI":"10.1016\/j.joms.2012.01.028","volume":"70","author":"C Bonet","year":"2012","unstructured":"Bonet C, Pe\u00f1arrocha-Oltra D, Minguez JM, Vera-Sierra B, Pe\u00f1arrochaDiago M, Pe\u00f1arrocha-Diago M. Oral teratomas: a report of 5 cases. J Oral Maxillofac Surg. 2012;70:2809\u201313.","journal-title":"J Oral Maxillofac Surg"},{"key":"3007_CR8","first-page":"128","volume":"16","author":"P Fister","year":"2007","unstructured":"Fister P, Volavsek M, Novosel S, Jazbec J. A newborn baby with a tumor protruding from the mouth. Diagnosis: congenital gingival granular cell tumor. Acta Dermatovenerol Alp Panon Adriat. 2007;16:128\u201330.","journal-title":"Acta Dermatovenerol Alp Panon Adriat"},{"issue":"1","key":"3007_CR9","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.bjoms.2007.12.015","volume":"47","author":"R Benson","year":"2009","unstructured":"Benson R, Fabbroni G, Russel J. A large teratoma of the hard palate: a case report. Br J Oral Maxillofac Surg. 2009;47(1):46\u20139.","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"3","key":"3007_CR10","first-page":"56","volume":"1","author":"S Kumar","year":"2011","unstructured":"Kumar S, Shrilkrishna U, Shetty S, Sitaram A. 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A copy of the written consent is available for the review of the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The author(s) declare no potential conflicts of interest with respect to the research, authorship, and\/or publication of this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"422"}}