{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:14:14Z","timestamp":1740147254026,"version":"3.37.3"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T00:00:00Z","timestamp":1631577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T00:00:00Z","timestamp":1631577600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100008793","name":"Universidad del Rosario","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008793","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Cluster headache is a primary condition characterized by severe headache accompanied by trigeminal autonomic signs. By definition, it is not attributed to underlying etiologies; however, under certain clinical characteristics, secondary etiologies must be ruled out.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We present the case of a 48-year-old Hispanic man with a history of episodic right orbital pain, lasting 30\u00a0minutes, associated with ipsilateral tearing, who prior to the onset of his symptoms reported loss of appetite, weight loss, and paresthesias in the right chin region. After work-up studies, high-grade lymphoma with infiltration to the right submental nerve was diagnosed, in which numb chin syndrome was the initial presentation. Despite initiation of treatment, the patient died 3\u00a0weeks after the diagnosis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>In the study of cluster headache, underlying etiologies must be considered when there are atypical clinical manifestations. Within these etiologies, metastases to pericranial nerves must be included, which, besides generating localized symptoms, can activate the trigeminal vascular system simulating headaches of primary etiology.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-03016-9","type":"journal-article","created":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T23:04:59Z","timestamp":1631574299000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Secondary cluster headache and numb chin syndrome as initial manifestation of high-grade B-lymphoma: a case report"],"prefix":"10.1186","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3318-9351","authenticated-orcid":false,"given":"Joe","family":"Munoz-Cer\u00f3n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"D\u00edaz-Forero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Buitrago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Chinchilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,9,14]]},"reference":[{"key":"3016_CR1","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1111\/j.1468-2982.2008.01567.x","volume":"28","author":"J Kim","year":"2008","unstructured":"Kim J, Lee S, Choi S, Park M, Kim B, Kim M, et\u00a0al. Spontaneous vertebral artery dissection mimicking cluster headache. Cephalalgia. 2008;28:671\u20133.","journal-title":"Cephalalgia"},{"key":"3016_CR2","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1111\/j.1468-2982.2006.01126.x","volume":"26","author":"M Volcy","year":"2006","unstructured":"Volcy M, Tepper SJ. Cluster-like headache secondary to idiopathic intracranial hypertension. Cephalalgia. 2006;26:883\u20136.","journal-title":"Cephalalgia"},{"key":"3016_CR3","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1046\/j.1468-2982.1989.904265.x","volume":"9","author":"J Hannerz","year":"1989","unstructured":"Hannerz J. A case of parasellar meningioma mimicking cluster headache. Cephalalgia. 1989;9:265\u20139.","journal-title":"Cephalalgia"},{"key":"3016_CR4","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5850286","author":"M Branco","year":"2018","unstructured":"Branco M, Rodrigues R, Lopes M, Ruano L. Case report cluster-like headache secondary to sphenoid sinus mucocele. Case Rep Neurol Med. 2018. https:\/\/doi.org\/10.1155\/2018\/5850286.","journal-title":"Case Rep Neurol Med."},{"key":"3016_CR5","doi-asserted-by":"crossref","unstructured":"The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1\u2013211.","DOI":"10.1177\/0333102417738202"},{"issue":"1","key":"3016_CR6","doi-asserted-by":"publisher","first-page":"e0208728","DOI":"10.1371\/journal.pone.0208728","volume":"14","author":"J Munoz-Ceron","year":"2019","unstructured":"Munoz-Ceron J, Marin-Careaga V, Pe\u00f1a L, Mutis J, Ortiz G. Headache at the emergency room: etiologies, diagnostic usefulness of the ICHD 3 criteria, red and green flags. PLoS ONE. 2019;14(1):e0208728.","journal-title":"PLoS ONE"},{"key":"3016_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2193-1801-3-1","volume":"3","author":"B Edvardsson","year":"2014","unstructured":"Edvardsson B. Symptomatic cluster headache\u202f: a review of 63 cases. SpringerPlus. 2014;3:1\u20138.","journal-title":"SpringerPlus."},{"key":"3016_CR8","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1111\/ejh.12763","volume":"97","author":"MF Zahid","year":"2016","unstructured":"Zahid MF, Khan N, Hashmi SK, Kizilbash SH, Barta SK. Central nervous system prophylaxis in diffuse large B-cell lymphoma. Eur J Haematol. 2016;97:108\u201320.","journal-title":"Eur J Haematol"},{"key":"3016_CR9","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1016\/j.jfma.2017.07.002","volume":"116","author":"S Lu","year":"2017","unstructured":"Lu S, Huang S, Chen Y. Numb chin with mandibular pain or masticatory weakness as indicator for systemic malignancy\u2014a case series study. J Formos Med Assoc. 2017;116:897\u2013906.","journal-title":"J Formos Med Assoc"},{"key":"3016_CR10","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1111\/j.1526-4610.2009.01456.x","volume":"49","author":"G Lambru","year":"2009","unstructured":"Lambru G, Castellini P, Manzoni GC, Torelli P. Post-traumatic cluster headache: from the periphery to the central nervous system? Headache. 2009;49:1059\u201372.","journal-title":"Headache"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03016-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-021-03016-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03016-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T00:04:49Z","timestamp":1631577889000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-021-03016-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,14]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["3016"],"URL":"https:\/\/doi.org\/10.1186\/s13256-021-03016-9","relation":{},"ISSN":["1752-1947"],"issn-type":[{"type":"electronic","value":"1752-1947"}],"subject":[],"published":{"date-parts":[[2021,9,14]]},"assertion":[{"value":"16 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All information has been appropriately deidentified. This report was approved by Medical Ethic Committee of Rosario University (DVO 1179 CV1252).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declared no potential conflicts of interest with respect to the research, authorship, and\/or publication of this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"468"}}